Annals of Human Biology最新文献

Nanopore sequencing technology in forensic science: status quo and tendency. 纳米孔测序技术在法医学中的应用：现状与趋势。

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-06-11 DOI: 10.1080/03014460.2026.2679464

Tianzhen Gao, Wang He, Xin Feng, Bing Long, Deming Zhang

{"title":"Nanopore sequencing technology in forensic science: status quo and tendency.","authors":"Tianzhen Gao, Wang He, Xin Feng, Bing Long, Deming Zhang","doi":"10.1080/03014460.2026.2679464","DOIUrl":"10.1080/03014460.2026.2679464","url":null,"abstract":"Context: Next-generation sequencing (NGS) is widely used in forensics for high throughput but limited by short reads and high non-batch testing costs. Third-generation sequencing (TGS), especially Oxford Nanopore Technologies (ONT) nanopore sequencing, with ultra-long reads, portability, real-time sequencing and amplification-free detection, addresses NGS's forensic technical bottlenecks.Objective: This study systematically reviews nanopore sequencing's current status in forensic genetics, explores its potential applications, clarifies its advantages and optimisation directions, and discusses practical challenges, to provide a comprehensive reference for its widespread forensic adoption.Methods: Bibliometric analysis was conducted on English literature retrieved from PubMed, Web of Science and Scopus using keywords like \"nanopore sequencing + forensic\" (retrieval up to February 2026). Relevant literature was also summarised for technical principles, performance, applications and challenges.Results: Nanopore sequencing has unique forensic advantages (ultra-long reads for haplotype analysis, direct methylation/RNA detection, portability). Bibliometric analysis showed staged research development, with the Netherlands leading, Europe as the collaboration core, and hotspots shifting to frontier applications. Technical optimisations improved accuracy, but bottlenecks like low-input sample processing and standardisation remain.Conclusion: Nanopore sequencing supplements traditional forensic sequencing with broad prospects. With hardware/bioinformatics optimisation, multi-laboratory validation and unified standards, it is expected to be widely used in routine forensics in 3-5 years, supporting judicial justice.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2679464"},"PeriodicalIF":1.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148220301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Shorter maternal body height increases the risk of emergency caesarean section in a population with a high standard of prenatal care. 在产前护理水平较高的人群中，产妇身高较短增加了紧急剖腹产的风险。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-01-06 DOI: 10.1080/03014460.2025.2603208

R Rungger, B Hartmann, S Kirchengast

{"title":"Shorter maternal body height increases the risk of emergency caesarean section in a population with a high standard of prenatal care.","authors":"R Rungger, B Hartmann, S Kirchengast","doi":"10.1080/03014460.2025.2603208","DOIUrl":"10.1080/03014460.2025.2603208","url":null,"abstract":"Caesarean sections (CS) are the most common surgical procedures performed on women of reproductive age. They should only be performed when medically indicated or in case of acute birth complications. Assessing risk factors that could necessitate a CS is therefore of great interest. The aim of this retrospective medical record-based study was to analyse the significance of maternal height as a risk factor for emergency CS using a data set of 11,110 term births in Vienna, Austria. The emergency CS rate was 8.2%. Mothers experiencing emergency CS were significantly older, shorter, but heavier and more likely to be first-time mothers than women experiencing spontaneous vaginal childbirth. Very short mothers (< 156 cm) had the significantly highest (p < 0.001) emergency CS rate, while women with a height of > 175 cm had the lowest. Maternal height was an independent risk factor for emergency CS. For every centimetre decrease in height, the risk of an emergency CS increased significantly by 6.7%. Maternal height should therefore be considered a risk factor for birth complications that could require an emergency CS, even in a population with a very high standard of prenatal care.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2603208"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between CHRNA5 polymorphisms and Parkinson's disease in Northern Chinese Han population: a case-control study. 中国北方汉族人群CHRNA5多态性与帕金森病的关系：一项病例对照研究

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-06-22 DOI: 10.1080/03014460.2026.2682270

Wenke Xian, Xiaohui Sun, Yue Wang, Xiaohui Sun, Jing Zhang, Kunpeng Qin, Yuting Zhou, Qiqing He, Yaqing Li, Anmu Xie, Binghui Hou

{"title":"Association between CHRNA5 polymorphisms and Parkinson's disease in Northern Chinese Han population: a case-control study.","authors":"Wenke Xian, Xiaohui Sun, Yue Wang, Xiaohui Sun, Jing Zhang, Kunpeng Qin, Yuting Zhou, Qiqing He, Yaqing Li, Anmu Xie, Binghui Hou","doi":"10.1080/03014460.2026.2682270","DOIUrl":"10.1080/03014460.2026.2682270","url":null,"abstract":"Background: Parkinson's disease (PD) is a complex neurodegenerative disorder characterised by the progressive loss of dopaminergic neurons in the substantia nigra, resulting in motor symptoms such as bradykinesia, resting tremor, rigidity, and postural instability.Aim: This study investigated the association between two single nucleotide polymorphisms of the nicotinic choline receptors α5 (CHRNA5), and the likelihood of developing PD among individuals from the Northern Han Chinese community.Subjects and methods: A retrospective case-control study included 400 PD patients and 400 age- and sex-matched healthy controls. We detected CHRNA5 variants using polymerase chain reaction-restriction fragment length polymorphism and analysed the data with R(4.2.0).Results: The rs680244 TT genotype was associated with an increased risk of PD (OR = 1.801, 95% CI: 1.050-3.089, nominal p = 0.031), with a similar association observed under the recessive model (OR = 1.786, 95% CI: 1.056-3.080, nominal p = 0.033). In the male subgroup (198 PD cases and 220 controls), the T allele was also associated with increased PD risk (OR = 1.356, 95% CI: 1.025-1.854, nominal p = 0.040). However, none of these associations remained statistically significant after multiple testing correction using the Bonferroni method. No statistically significant associations were observed for rs495090 in any of the analyses performed.Conclusion: The CHRNA5 rs680244 T allele showed a suggestive association with sporadic PD susceptibility in the Northern Han Chinese population. However, these findings should be interpreted with caution and require validation in larger cohorts across different ethnic populations and clinical settings, ideally with smoking-related data available.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2682270"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Limited efficacy of low-volume ice slurry ingestion on physiological heat strain in Japanese outdoor workers during summer. 低剂量冰浆摄入对夏季日本户外工作者生生性热应激的有限效果。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-07-30 DOI: 10.1080/03014460.2026.2705279

Hiroki Mani, Fumitsugu Io, Keiichi Ohba, Yasuhiro Sonoda

{"title":"Limited efficacy of low-volume ice slurry ingestion on physiological heat strain in Japanese outdoor workers during summer.","authors":"Hiroki Mani, Fumitsugu Io, Keiichi Ohba, Yasuhiro Sonoda","doi":"10.1080/03014460.2026.2705279","DOIUrl":"10.1080/03014460.2026.2705279","url":null,"abstract":"Background: Occupational heat exposure is a growing public health concern in Japan, where hot, humid summers contribute to heat-related illnesses (HRIs).Aim: To characterise the thermophysiological responses of Japanese outdoor workers to summer heat exposure and explore the effect of a practical pre-cooling approach.Subjects and methods: Two field-based experiments were conducted in August-September. In Experiment 1, heart rate (HR) and core body temperature (CT) were continuously monitored under routine working conditions. In Experiment 2, workers performed their duties after pre-work ingestion of a 100 g carbohydrate-electrolyte ice slurry. HR and CT were assessed using non-invasive wearable sensors, and subjective thermal perception was recorded during the workday.Results: Under high environmental heat stress (maximum Wet Bulb Globe Temperature: 30.2 ± 2.4 °C and 29.4 ± 2.1 °C), both CT and HR increased significantly during midday and afternoon periods. No significant differences were observed between the conditions in terms of HR, CT, or subjective thermal perception.Conclusion: Japanese outdoor workers exhibited a sustained elevation in thermo-physiological strain during summer. A low-volume pre-cooling strategy did not measurably modify these responses, indicating a limited physiological impact under real-world conditions.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2705279"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148622279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growth and adiposity patterns in Argentine children with Prader-Willi syndrome without growth hormone treatment or individualised very low energy diets. 未经生长激素治疗或个体化极低能量饮食的阿根廷普瑞德-威利综合征儿童的生长和肥胖模式

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-10-07 DOI: 10.1080/03014460.2026.2739501

Silvia Caino, Carolina Caminiti, Rocio Rabosto Moleón, Gabriela Krochik, Mariana Del Pino

{"title":"Growth and adiposity patterns in Argentine children with Prader-Willi syndrome without growth hormone treatment or individualised very low energy diets.","authors":"Silvia Caino, Carolina Caminiti, Rocio Rabosto Moleón, Gabriela Krochik, Mariana Del Pino","doi":"10.1080/03014460.2026.2739501","DOIUrl":"https://doi.org/10.1080/03014460.2026.2739501","url":null,"abstract":"Background: Children with Prader-Willi syndrome (PWS) show distinctive patterns of growth and body composition. Although growth hormone (GH) therapy is widely used, many patients continue to be monitored without treatment, making anthropometric data from untreated populations valuable for clinical follow-up. We previously developed Argentine references for height and body segments in GH-untreated children with PWS.Aim: To extend that work by characterising patterns of adiposity using weight, body mass index (BMI), and skinfold thickness measurements in children with PWS who had not received GH therapy or individualised very low energy diets.Subjects and methods: Anthropometric data were obtained from clinically and genetically confirmed patients followed at a tertiary paediatric hospital. Measurements included weight, BMI, and triceps, bicipital, suprailiac, and subscapular skinfolds. Age and sex specific curves were generated using the LMS method. A total of 167 children were included (82 males, 85 females) with a total of 1,119 weight, 1,009 BMI, 815 triceps skinfold, 643 biceps skinfold and 615 suprailiac skinfold measurements.Results: Weight and BMI centiles showed an early upward shift after the second year of life, with the greatest divergence occurring in early childhood. Skinfold thicknesses were consistently elevated across ages, including in infants and young children, indicating early alterations in body composition.Conclusion: Together with previously published Argentine linear growth references, these findings provide a more comprehensive framework for evaluating growth and body composition, particularly adiposity trajectories in children with PWS.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2739501"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Nick Norgan Award 2025. 2025年尼克·诺根奖。

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-02-09 DOI: 10.1080/03014460.2026.2623696

引用次数: 0

Observation of the therapeutic effect of flunarizine capsules combined with the Epley manoeuvre in the treatment of benign paroxysmal positional vertigo. 氟桂利嗪胶囊联合Epley手法治疗良性阵发性位置性眩晕的疗效观察。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-05-28 DOI: 10.1080/03014460.2026.2669064

Yongjun Zhu, Hao Zhou, Dachuan Fan, Xiaobo Li, Jianming Yang

{"title":"Observation of the therapeutic effect of flunarizine capsules combined with the Epley manoeuvre in the treatment of benign paroxysmal positional vertigo.","authors":"Yongjun Zhu, Hao Zhou, Dachuan Fan, Xiaobo Li, Jianming Yang","doi":"10.1080/03014460.2026.2669064","DOIUrl":"10.1080/03014460.2026.2669064","url":null,"abstract":"Background: The Epley manoeuvre is the standard treatment for benign paroxysmal positional vertigo (BPPV) and flunarizine shows potential in vertigo-related disorders, however, evidence on their combined use remains limited.Aim: This retrospective study aimed to observe the therapeutic effect of flunarizine capsules plus Epley manoeuvre in patients with benign paroxysmal positional vertigo.Subjects and methods: Eighty BPPV patients were divided into the control group (only the Epley manoeuvre) and the study group (flunarizine hydrochloride capsules alongside it). The therapeutic effects were observed after two weeks-treatment. The clinical treatment effective rates, DHI, VSI, BBS, cerebral blood flow velocities, and vestibular function test were compared. Patients were followed for one year to record recurrence and adverse events. Total effective rate included markedly effective and effective cases.Results: The study group had a higher overall response rate (p < 0.05). Repeated-measures ANOVA showed significant post-treatment improvements in DHI, VSI, and BBS scores, with significant time × group interaction effects (p < 0.001). Cerebral blood flow velocities improved post-treatment, with significant time × group interactions (p < 0.05). Vestibular function improved post-treatment, but the main effect and time × group interaction did not reach statistical significance (p > 0.05). Recurrence was lower in the study group (p < 0.05).Conclusion: Flunarizine plus Epley manoeuvre is associated with better efficacy, symptom relief, cerebral blood flow, vestibular compensation, and lower recurrence in BPPV, with no increase in adverse events.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2669064"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148058215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective association of the ELMO1 rs741301 variant against diabetes mellitus and diabetic nephropathy: a systematic meta-analysis of case-control studies. ELMO1 rs741301变异与糖尿病和糖尿病肾病的保护性关联：一项病例对照研究的系统荟萃分析

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-09-02 DOI: 10.1080/03014460.2026.2723114

Sheena Mariam Thomas, Anu Shibi Anilkumar, Ramakrishnan Veerabathiran

{"title":"Protective association of the ELMO1 rs741301 variant against diabetes mellitus and diabetic nephropathy: a systematic meta-analysis of case-control studies.","authors":"Sheena Mariam Thomas, Anu Shibi Anilkumar, Ramakrishnan Veerabathiran","doi":"10.1080/03014460.2026.2723114","DOIUrl":"10.1080/03014460.2026.2723114","url":null,"abstract":"Context: Diabetes mellitus (DM), an endocrine disorder, is characterised by persistently elevated blood glucose levels due to inadequate insulin production. Diabetic nephropathy (DN), is a critical complication associated with DM, often leading to end-stage renal failure and increased mortality.Objective: This meta-analysis aimed to evaluate the association between the ELMO1 rs741301 polymorphism and susceptibility to DN among individuals with diabetes.Method: A systematic literature search was conducted for studies published between 2014 and 2024 using Embase, Google Scholar, and PubMed. Eligible case-control studies investigating the association between ELMO1 rs741301 and DN among individuals with DM were selected according to predefined inclusion criteria. Nine case-control studies comprising 880 individuals with DM and 1008 individuals with DN were included in the meta-analysis.Results: The pooled analysis demonstrated a significant protective association between the ELMO1 rs741301 polymorphism and DN under the allelic model (OR = 0.77, 95% CI: 0.67-0.88), recessive model (OR = 0.74, 95% CI: 0.61-0.90), and dominant model (OR = 0.68, 95% CI: 0.53-0.88). In contrast, no statistically significant association was observed under the over-dominant model.Conclusion: The findings suggest that the ELMO1 rs741301 polymorphism may be associated with a reduced susceptibility to DN among individuals with DM. These findings provide evidence for a potential genetic contribution of ELMO1 to DN susceptibility and may help improve understanding of the genetic factors underlying diabetic complications. Further well-designed studies in diverse populations are warranted to validate this association.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2723114"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between low-carbohydrate-diet score and osteoporosis in hypertensive patients: a cross-sectional study. 高血压患者低碳水化合物饮食评分与骨质疏松症的相关性：一项横断面研究。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-04-06 DOI: 10.1080/03014460.2026.2649751

Xi Liu, Haixia Ying, Qunxiang Wang, Sisi Liao, Bin Xu

{"title":"Association between low-carbohydrate-diet score and osteoporosis in hypertensive patients: a cross-sectional study.","authors":"Xi Liu, Haixia Ying, Qunxiang Wang, Sisi Liao, Bin Xu","doi":"10.1080/03014460.2026.2649751","DOIUrl":"10.1080/03014460.2026.2649751","url":null,"abstract":"Background: The low-carbohydrate diet (LCD) score reflects the relative intake of carbohydrates, protein, and fat. However, the association between LCD score and osteoporosis (OP) in hypertensive adults remains unclear.Subjects and methods: This cross-sectional study included hypertensive adults from the National Health and Nutrition Examination Survey (NHANES) 2005-2018. The LCD score was calculated based on participants' dietary intake. Logistic regression analysis was performed to evaluate the association between LCD score and OP. Restricted cubic spline (RCS) analysis was used to explore the dose-response relationship, and subgroup analyses were conducted to assess potential effect modification.Results: A total of 7,493 hypertensive adults were included in the study. After adjustment for covariates, each one-unit increase in LCD score was associated with a 2.1% lower odds of OP (OR = 0.979, 95% CI = 0.960-0.999). Compared with participants in the lowest quartile of LCD score, those in the highest quartile had significantly lower odds of OP (OR = 0.571, 95% CI = 0.388-0.840). RCS analysis showed a significant linear inverse association between LCD score and OP. Subgroup analyses showed that physical activity significantly modified this association.Conclusion: Higher LCD scores were inversely associated with OP in hypertensive adults. These findings suggest a potential role of dietary patterns in bone health management in this population.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2649751"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A method for the 3D quantification of enthesis rugosity. 一种内植性的三维量化方法。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-10-07 DOI: 10.1080/03014460.2026.2739497

Erin Marie Williams-Hatala, Allison J Rutledge, Michael L Collyer, Noah Bettinger, Lucas Tavares Naief, Karyne N Rabey, Angel Zeininger, Daniel Schmitt, Caley M Orr, Kevin G Hatala

{"title":"A method for the 3D quantification of enthesis rugosity.","authors":"Erin Marie Williams-Hatala, Allison J Rutledge, Michael L Collyer, Noah Bettinger, Lucas Tavares Naief, Karyne N Rabey, Angel Zeininger, Daniel Schmitt, Caley M Orr, Kevin G Hatala","doi":"10.1080/03014460.2026.2739497","DOIUrl":"https://doi.org/10.1080/03014460.2026.2739497","url":null,"abstract":"Introduction: Many methods for evaluating enthesis rugosity are qualitative or fail to capture the entire entheseal surface. Here we present a new 3D method quantifying rugosity across the entire entheseal surface and test it by measuring and comparing the rugosity of the opponens pollicis enthesis to a non-enthesis region on the same bone in a sample of great apes.Methods: To quantify rugosity, the enthesis area is isolated on high-resolution 3D models and deviations are measured between a best-fit surface and the 3D point cloud representing the enthesis.Results: We demonstrate that this method quantifies entheseal rugosity and is resilient to interobserver differences in defining entheseal boundaries. It is also sufficiently sensitive to detect intergeneri differences. In Gorilla, Homo, and Pan the magnitude of entheseal rugosity is significantly greater than non-entheseal rugosity. In Pongo, there are no significant differences between the two regions or between the entheseal region of Pongo and the non-entheseal regions of the other genera, indicating a unique pollical metacarpal morphology among great apes.Discussion: The results support the validity and repeatability of the method for measuring rugosity. The observed pattern of enthesis rugosity reaffirms a complex relationship among entheses, muscle anatomy, and behaviour.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2739497"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0