Annals of Human Biology最新文献_第2页

To be or not to be bitter? The knowns, and unknowns, of the genetics of phenylthiocarbamide perception. 苦还是不苦？苯硫甲酰胺感知遗传学的已知与未知。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-08-15 DOI: 10.1080/03014460.2024.2379900

Davide Risso, Dennis Drayna

引用次数: 0

Forensic parameters and population analysis of 21 autosomal STR loci in the Wuhu Han population from Anhui Province, East China. 华东安徽芜湖汉族人群 21 个常染色体 STR 位点的法医参数和人群分析。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-01-22 DOI: 10.1080/03014460.2023.2298470

Yanyan Yang, Qianqian Li, Xinrui Yang, Ziwei Zhang, Yongliang Hu, Yue Zhang, Fang He

{"title":"Forensic parameters and population analysis of 21 autosomal STR loci in the Wuhu Han population from Anhui Province, East China.","authors":"Yanyan Yang, Qianqian Li, Xinrui Yang, Ziwei Zhang, Yongliang Hu, Yue Zhang, Fang He","doi":"10.1080/03014460.2023.2298470","DOIUrl":"10.1080/03014460.2023.2298470","url":null,"abstract":"Background: At present, there are no available genetic data on the AGCU EX22 Kit from the Wuhu Han population.Aim: This study investigates the applicability of the AGCU EX22 kit, designed for the Chinese population for forensic analysis and population genetics of the Wuhu Han population.Subjects and methods: Bloodstains from 1565 unrelated healthy individuals in Wuhu city, Anhui Province, were collected for analysis. The AGCU EX22 kit was used for amplification, and capillary electrophoresis was used to separate the amplification products. Allele frequencies and forensic parameters were determined. The Wuhu Han population was compared to 10 reference populations through genetic distance, a phylogenetic neighbor-joining tree and principal component analysis.Results: In total, 281 alleles and 1187 genotypes were observed. No significant deviations from Hardy-Weinberg equilibrium at any locus were found after Bonferroni's correction. The 21 autosomal short tandem repeat (STR) genetic markers exhibited high informativeness and polymorphism. The cumulative power of discrimination and power of exclusion were 0.999999999999999999999999913380 and 0.999999996752339, respectively. Population comparisons revealed a genetic affinity between Wuhu Han and southern Han populations, except for the Guangdong Han population, which aligned with the traditional geographical division in China.Conclusion: The AGCU EX22 Kit, containing 21 STR loci, is suitable for forensic application and population genetics studies in the Wuhu Han population.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"1-6"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic polymorphism analysis and forensic application evaluation of 57 insertion/deletion polymorphisms from Yi ethnic group in Yunnan. 云南彝族 57 个插入/缺失多态性的遗传多态性分析和法医应用评估。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-01-22 DOI: 10.1080/03014460.2023.2294743

Kuo Zeng, Dong Zhao

{"title":"Genetic polymorphism analysis and forensic application evaluation of 57 insertion/deletion polymorphisms from Yi ethnic group in Yunnan.","authors":"Kuo Zeng, Dong Zhao","doi":"10.1080/03014460.2023.2294743","DOIUrl":"10.1080/03014460.2023.2294743","url":null,"abstract":"Background: As a new kind of diallelic genetic marker, insertion/deletion (InDel) polymorphisms have recently been used in forensic science. However, there are relatively few studies on the forensic evaluation of InDel genetic polymorphisms from different populations.Aim: The aim of the present work is to assess the genetic polymorphism and forensic applicability of 57 InDels from the Yi ethnic group and explore the genetic background of this group.Subjects and methods: A total sample of 122 unrelated individuals of Yi group from the Yunnan province were genotyped by the AGCU indel 60 Kit. Multiplex population genetic analyses on the same 57 InDels were carried out among the Yunnan Yi group and 29 reference populations.Results: The average allele frequency of these loci in the Yi ethnic group was 0.485. Heterozygosity, polymorphism information content, and the power of discrimination were 0.477, 0.362, and 0.612, respectively. The combined power of discrimination and the combined power of exclusion reached to 0.99999999999999999669 and 0.999962965, respectively. The results showed that 57 InDels polymorphisms have high genetic polymorphisms in the Yi ethnic group.Conclusions: The 57 InDels could be used for forensic individual identification, paternity testing, and intercontinental population discrimination, with the potential for use in biogeographic ancestry inference.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139514158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic variants in BDNF (rs6265 and rs11030119) and stroke susceptibility: a case-control analysis in South India. BDNF 基因变异（rs6265 和 rs11030119）与中风易感性：南印度的病例对照分析。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-11-04 DOI: 10.1080/03014460.2024.2415984

Anushree Muraleedharan Nair, Chandrasudan Ramamoorthi, Madhushri Arumugam Senthilkumar, Remasri Kanniyapillai, Praveen Kumar Chandra Sekar, Akram Husain Rehman Syed Rasheed, Subramaniyan Kannaian, Ramakrishnan Veerabathiran

{"title":"Genetic variants in BDNF (rs6265 and rs11030119) and stroke susceptibility: a case-control analysis in South India.","authors":"Anushree Muraleedharan Nair, Chandrasudan Ramamoorthi, Madhushri Arumugam Senthilkumar, Remasri Kanniyapillai, Praveen Kumar Chandra Sekar, Akram Husain Rehman Syed Rasheed, Subramaniyan Kannaian, Ramakrishnan Veerabathiran","doi":"10.1080/03014460.2024.2415984","DOIUrl":"https://doi.org/10.1080/03014460.2024.2415984","url":null,"abstract":"Background: Stroke occurs when the blood supply to part of the cerebral cortex is blocked, depriving it of oxygen and glucose, leading to cell death. It is a multifactorial disorder influenced by genetic, vascular, and environmental factors.Aim: This study investigated the association between two polymorphisms of the brain-derived neurotrophic factor (BDNF) gene, rs6265 and rs11030119, and stroke risk in a South Indian population.Subjects and methods: The study included 163 stroke cases and 160 healthy controls. Genomic DNA was extracted, and genotyping of rs6265 and rs11030119 polymorphisms was done using ARMS-PCR. Allelic and genotype frequencies were calculated, and odds ratios (OR) with 95% confidence intervals (CI) were determined using SPSS version 21.0.Results: The rs6265 polymorphism was significantly associated with stroke risk, with the GG genotype more frequent in controls (OR 1.79, 95% CI 1.05-1.76, p = 0.01). The rs11030119 polymorphism showed a positive association, with the AA genotype more prevalent in cases (OR 2.70, 95% CI 1.34-5.44, p = 0.003).Conclusion: This study suggests an association between BDNF polymorphisms (rs6265, rs11030119) and stroke risk in a South Indian population. Further research in larger populations is necessary to confirm these findings and explore the mechanisms involved.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2415984"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between dietary inflammation index and frailty in patients with osteoarthritis. 骨关节炎患者饮食炎症指数与虚弱之间的关系。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-07-09 DOI: 10.1080/03014460.2024.2369274

Feng Zhao, Fang Pan, Jian Li

{"title":"Relationship between dietary inflammation index and frailty in patients with osteoarthritis.","authors":"Feng Zhao, Fang Pan, Jian Li","doi":"10.1080/03014460.2024.2369274","DOIUrl":"https://doi.org/10.1080/03014460.2024.2369274","url":null,"abstract":"Background: Osteoarthritis (OA) is a common chronic joint disease that significantly affects an individual's quality-of-life and frailty has become one of the common complications in OA patients as the disease progresses. The relationship between dietary patterns is not clear.Methods: All participants are from the National Health and Nutrition Examination Survey (NHANES) and have been diagnosed with OA. The dietary inflammation index (DII) is calculated based on the dietary intake reported by the participants. Logistic regression analysis is used to investigate the relationship between DII and frailty. Restricted cubic splines are utilised to explore their nonlinear relationship. Mediation analysis is conducted to explore the role of inflammation in this relationship.Results: A total of 2,530 OA patients were included in the study, with an average age of 64.46 (12.67) years. After adjusting for covariates, for each one standard deviation increase in DII, the risk of frailty increased by 15% (OR = 1.15, 95% CI = 1.03-1.28). Compared to patients with DII < -1, patients with DII > 1 had a significantly higher risk of frailty (OR = 1.50, 95% CI = 1.05-2.14).Conclusions: The findings of this study indicate a positive association between DII and the risk of frailty in OA patients. These results underscore the potential impact of dietary interventions in improving the quality-of-life for OA patients.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2369274"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141560276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Worldwide distribution of genetic factors related to severity of COVID-19 infection. 与 COVID-19 感染严重程度有关的遗传因素在全球的分布情况。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-07-16 DOI: 10.1080/03014460.2024.2366248

María Esther Esteban, Débora Pino, Alicia Romero-Lorca, Apolonia Novillo, María Gaibar, José A Riancho, Augusto Rojas-Martínez, Carlos Flores, Pablo Lapunzina, Ángel Carracedo, Georgios Athanasiadis, Ana Fernández-Santander

{"title":"Worldwide distribution of genetic factors related to severity of COVID-19 infection.","authors":"María Esther Esteban, Débora Pino, Alicia Romero-Lorca, Apolonia Novillo, María Gaibar, José A Riancho, Augusto Rojas-Martínez, Carlos Flores, Pablo Lapunzina, Ángel Carracedo, Georgios Athanasiadis, Ana Fernández-Santander","doi":"10.1080/03014460.2024.2366248","DOIUrl":"https://doi.org/10.1080/03014460.2024.2366248","url":null,"abstract":"Background: Genome-wide association studies of COVID-19 severity have been carried out mostly on European or East Asian populations with small representation of other world regions. Here we explore the worldwide distribution and linkage disequilibrium (LD) patterns of genetic variants previously associated with COVID-19 severity.Methods: We followed up the results of a large Spanish genome-wide meta-analysis on 26 populations from the 1000 Genomes Project by calculating allele frequencies and LD scores of the nine most significant SNPs. We also used the entire set of summary statistics to compute polygenic risk scores (PRSs) and carried out comparisons at the population and continental level.Results: We observed the strongest differences among continental regions for the five top SNPs in chromosome 3. European, American, and South Asian populations showed similar LD patterns. Average PRSs in South Asian and American populations were consistently higher than those observed in Europeans. While PRS distributions were similar among South Asians, the American populations showed striking differences among them.Conclusions: Considering the caveats of PRS transferability across ethnicities, our analysis showed that American populations present the highest genetic risk score, hence potentially higher propensity, for COVID-19 severity. Independent validation is warranted with additional summary statistics and phenotype data.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2366248"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico. 墨西哥尤卡坦州农村玛雅儿童的出生体重及其与心脏代谢风险参数的关系。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-03-13 DOI: 10.1080/03014460.2024.2323037

Julio Lara-Riegos, Hugo Azcorra, Juan Carlos Salazar-Rendón, Víctor Arana-Argáez, María Teresa Castillo-Burguete, Nina Mendez-Dominguez

{"title":"Birthweight and its association with cardiometabolic risk parameters in rural Maya children from Yucatan, Mexico.","authors":"Julio Lara-Riegos, Hugo Azcorra, Juan Carlos Salazar-Rendón, Víctor Arana-Argáez, María Teresa Castillo-Burguete, Nina Mendez-Dominguez","doi":"10.1080/03014460.2024.2323037","DOIUrl":"10.1080/03014460.2024.2323037","url":null,"abstract":"Background: Knowledge about the influence of early developmental factors on cardiometabolic health in the Maya is limited.Aim: To analyse the relationship between birthweight (BW) and cardiometabolic parameters in a sample of rural Maya children from Yucatan, Mexico.Subjects and methods: We took anthropometric measurements and obtained data on BW and fasting blood samples in a sample of 75 children aged 5-14 years. Dependent variables were: fat mass index (FMI), body mass index (BMI), glucose (G), triglycerides (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL), low-density lipoprotein cholesterol (LDL), LDL/HDL and TC/HDL ratios and metabolic index (TGxG/HDL2). Outcomes were transformed to y = 100 log(e)x and the resulting estimates are interpreted as symmetrical percentage differences. The main independent variable was BW z-score. Multiple linear regression analyses were used to assess the relationship between BW and outcomes.Results: An increase of one standard deviation in BW predicted 6.6% (95% CI [-11.6, -1.6]) decrease in HDL and 11% (95% CI [3.7, 18.4]), 7.8% (95% CI [2.3, 13.2]) and 19.6% (95% CI [3.1, 36]) increases in LDL/HDL, TC/HDL and metabolic index, respectively.Conclusion: Higher birthweights were associated with adverse levels of biochemical parameters in this sample of rural Maya children.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2323037"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual burden of infectious and chronic disease in low-resource U.S. communities: examining relationships between infection, adiposity, and inflammation. 美国低资源社区传染病和慢性病的双重负担：研究感染、肥胖和炎症之间的关系。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-06-27 DOI: 10.1080/03014460.2024.2368851

Theresa E Gildner, Samuel S Urlacher, Katherine L Nemeth, Jade A Beauregard, Marcela Pfaff Nash, Angela Zhang, Sophie Waimon, Tara J Cepon-Robins

{"title":"Dual burden of infectious and chronic disease in low-resource U.S. communities: examining relationships between infection, adiposity, and inflammation.","authors":"Theresa E Gildner, Samuel S Urlacher, Katherine L Nemeth, Jade A Beauregard, Marcela Pfaff Nash, Angela Zhang, Sophie Waimon, Tara J Cepon-Robins","doi":"10.1080/03014460.2024.2368851","DOIUrl":"https://doi.org/10.1080/03014460.2024.2368851","url":null,"abstract":"Background: Rising global obesity rates are linked with inflammation and associated morbidities. These negative outcomes are generally more common in low-resource communities within high-income countries; however, it is unclear how frequent infectious disease exposures in these settings may influence the relationship between adiposity and inflammation.Aim: We test associations between adiposity measures and distinct forms of inflammation among adults (n = 80) living in low-resource U.S. communities experiencing high levels of obesity and pathogen exposure.Subjects and methods: Adiposity measures included BMI and percent body fat. Inflammation measures included systemic inflammation (C-reactive protein [CRP]) and localised intestinal inflammation (faecal calprotectin [FC]). The relationship between a condition characterised by elevated inflammation (Helicobacter pylori infection) and adiposity was also considered.Results: Adiposity was not significantly related to FC concentration. However, both adiposity measures were positively related with odds of CRP elevation and H. pylori infection was associated with significantly lower adiposity measures (all p < 0.05).Conclusion: For this disadvantaged U.S. sample, the association between adiposity and inflammation varies by the systemic/localised nature of inflammation and the likely underlying cause of inflammation. Defining these associations will improve understanding of how rising obesity rates shape long-term health inequities, with implications for more effective intervention design.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2368851"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Childhood developmental environment affects adult intestinal inflammation levels: preliminary evidence from older adults in the United States. 儿童发育环境影响成人肠道炎症水平：来自美国老年人的初步证据。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-12-05 DOI: 10.1080/03014460.2024.2427593

Courtney Manthey, Meg Super, Tara J Cepon-Robins

{"title":"Childhood developmental environment affects adult intestinal inflammation levels: preliminary evidence from older adults in the United States.","authors":"Courtney Manthey, Meg Super, Tara J Cepon-Robins","doi":"10.1080/03014460.2024.2427593","DOIUrl":"https://doi.org/10.1080/03014460.2024.2427593","url":null,"abstract":"Background: The Old Friends Hypothesis suggests limited exposure to symbionts during development leads to immune system dysregulation (e.g. allergies, autoimmunity) and inflammatory conditions (e.g. inflammatory bowel disease), with likely sex-specific variation based on exposure risk and sex hormones. Limited research documents how variation in childhood exposures affect older adult health.Aim: We tested relationships between current intestinal inflammation and childhood environment in 84 older adults (51-88 years) living in Colorado, USA.Subjects and methods: Faecal calprotectin (FC), a biomarker of intestinal inflammation, was measured from stool samples. Structured interviews assessed farm animal exposure during childhood and childhood environments (urban, suburban, rural) at different age periods (0 to 5, 5 to 10, 10 to 20 years).Results and conclusions: Farm animal exposure was not significantly associated with FC. Females who grew up in suburban environments, especially between the ages of 5 and 10, had higher FC than females from urban or rural environments (p < 0.05). Males living in urban environments between the ages of 10 and 20 had the lowest FC compared to both other environments (p < 0.05). We found mixed, age- and sex-specific support for the idea that childhood exposures alter risk of inflammatory disease later in life.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2427593"},"PeriodicalIF":1.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Health status and public health needs in a Togolese child health care centre modelled after the Dutch system. 多哥儿童医疗保健中心的健康状况和公共卫生需求仿照荷兰的系统。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2024-02-01 Epub Date: 2024-05-03 DOI: 10.1080/03014460.2024.2342529

Paula van Dommelen, Cécile Schat-Savy, Arjan Huizing, Symone Detmar, Leonhard A Bakker, Paul H Verkerk

{"title":"Health status and public health needs in a Togolese child health care centre modelled after the Dutch system.","authors":"Paula van Dommelen, Cécile Schat-Savy, Arjan Huizing, Symone Detmar, Leonhard A Bakker, Paul H Verkerk","doi":"10.1080/03014460.2024.2342529","DOIUrl":"https://doi.org/10.1080/03014460.2024.2342529","url":null,"abstract":"Background: The charity foundation Association Soutien Enfants Togo started a child health care (CHC) centre in Togo that was modelled after the Dutch high-quality CHC system to improve child health.Aim: To describe health care data of children who visited the centre.Subjects and methods: Data were routinely collected between October 2010-July 2017. Outcomes were completed vaccinations, growth, development, lifestyle, physical examination, and laboratory testing results.Results: In total, 8,809 children aged 0-24 years were available. Half (47.5%) of children aged 0-4 years did not receive all eligible free vaccinations from the government. The proportions of stunted children (all) or with a developmental delay (0-4 years) were 10.1% and 9.5%, respectively. In total, 40-50% of all children did not wash their hands with soap after toilet or before eating, or did not use clean drinking water. Furthermore, 5.1-6.6% had insufficient vision, high eye pressure or hearing loss. Sickle cell disease was detected in 5.3%.Conclusion: A large group of children in need of prevention and early treatment were detected, informed and treated by the centre. Further research is needed to confirm if this strategy can improve children's health in Sub-Saharan Africa. Our data are available for further research.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"51 1","pages":"2342529"},"PeriodicalIF":1.7,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0