Annals of Human Biology最新文献

{"title":"Effects of orthodontic treatment on masticatory muscles activity: a meta-analysis.","authors":"Yuxiang Zhan,&nbsp;Minjie Yang,&nbsp;Shuoqiu Bai,&nbsp;Siqin Zhang,&nbsp;Yunqin Huang,&nbsp;Fansheng Gong,&nbsp;Xiaolin Nong","doi":"10.1080/03014460.2023.2271840","DOIUrl":"https://doi.org/10.1080/03014460.2023.2271840","url":null,"abstract":"<p><p><b>Context:</b> A comprehensive meta-analysis was carried out to investigate the impact of orthodontics on masticatory muscles.<b>Methods:</b> A thorough search of various databases, including CNKI, Wan Fang, VIP, CBM, MEDLINE, PubMed, Cochrane Library, EMBASE, Web of Science, and Google Scholar, was performed to identify relevant studies on patients undergoing orthodontics or functional corrections. Six case-control studies were finally included in this analysis, which specifically examined the effect of orthodontic treatment on masticatory muscle function.<b>Results:</b> The results revealed that the mean masticatory muscle voltage in patients treated with orthodontics was found to be higher after treatment compared to before treatment [odds ratio (OR)=1.57, 95% confidence interval (CI) (0.57, 2.57), <i>p</i> = 0.002], which could potentially have an impact on masticatory muscle function, particularly in individuals with Class II Division 1 malocclusion.<b>Conclusion:</b> These findings contribute to our understanding of the effects of orthodontic interventions on masticatory muscles, further highlighting the importance of orthodontics in optimising masticatory function.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71488504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between cadmium and cognition in the elderly: a systematic review.","authors":"Xueke Yang,&nbsp;Lijing Xi,&nbsp;Zhaoyan Guo,&nbsp;Li Liu,&nbsp;Zhiguang Ping","doi":"10.1080/03014460.2023.2168755","DOIUrl":"https://doi.org/10.1080/03014460.2023.2168755","url":null,"abstract":"<p><p><b>Context:</b> The relationship between cadmium (Cd) and the cognition of the elderly is indistinct.<b>Objective:</b> To summarise the studies on the relationship between the cognition of the elderly and Cd.<b>Methods:</b> Literatures were searched in PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Wan fang database on April 25, 2022. The entries in the STROBE statement were used to evaluate the literature quality; all the quantitative studies that met the requirements were systematically summarised.<b>Results:</b> Blood Cd was negatively correlated with the cognitive ability of the elderly, corresponding to different cognitive ability assessment methods, the regression coefficients were: -0.11 (-0.20, -0.03), -0.46 (-0.71, -0.21), -0.54 (-0.90, -0.17), -0.19 (-0.37, -0.01), and -2.29 (-3.41, -1.16). The regression coefficients between urinary Cd level and cognition score were -1.42 (-2.38, -0.46), and 0.76 (-1.28, -0.23). When dietary Cd increased by 1 μg/kg, the composite z-score decreased by 3.64 (<i>p</i> = 0.001). There was no significant correlation between drinking water Cd, fingernail Cd and cognition (<i>p</i> > 0.05).<b>Conclusion:</b> We concluded that blood Cd (including whole blood and plasma), urine Cd and dietary Cd were negatively correlated with the cognition of the elderly, but the relationship between Cd in drinking water and fingernails and cognition was not statistically significant.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9332007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of body size and training environment on the physical performance of adolescent basketball players: the INEX study.","authors":"Eduardo Guimarães,&nbsp;Adam D G Baxter-Jones,&nbsp;A Mark Williams,&nbsp;Fernando Tavares,&nbsp;Manuel A Janeira,&nbsp;José Maia","doi":"10.1080/03014460.2023.2169759","DOIUrl":"https://doi.org/10.1080/03014460.2023.2169759","url":null,"abstract":"<p><strong>Background: </strong>Although adolescent basketballers differ in body size, shape, and composition, less is known about how these factors interact during physical development.</p><p><strong>Aim: </strong>We used ontogenetic allometry to identify the optimal body size and shape characteristics associated with physical performance in adolescent basketball players, and investigated the effects of training experience, training volume, maturity status, and club characteristics on physical performance development.</p><p><strong>Subjects and methods: </strong>Two hundred and sixty-four male basketballers, from five age-cohorts (11-15 years of age), were followed consecutively over three years. Three physical performance components, anthropometrics, training information, and biological maturation were assessed bi-annually. Longitudinal multiplicative allometric models were developed.</p><p><strong>Results: </strong>Players with a physique that had a dominant ectomorphic component performed better in all physical performance components. When adjusting for confounders other than size, the development of running speed was independent of body size. Players advanced in maturation were physically fitter. Training data had no significant effect on developmental trajectories of running speed or lower body explosive strength. Club characteristics had no significant association with any physical performance trajectories.</p><p><strong>Conclusion: </strong>Leaner players have advantages in physical performance and individual characteristics play an important role, over and beyond club structure, in developing physical performance.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10673387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep phenotyping of pubertal development in Norwegian children: the Bergen Growth Study 2.","authors":"Petur B Juliusson,&nbsp;Ingvild S Bruserud,&nbsp;Ninnie Helen Bakken Oehme,&nbsp;Andre Madsen,&nbsp;Ingvild H Forthun,&nbsp;Melissa Balthasar,&nbsp;Karen Rosendahl,&nbsp;Kristin Viste,&nbsp;Astanand Jugessur,&nbsp;Lawrence M Schell,&nbsp;Robert Bjerknes,&nbsp;Mathieu Roelants","doi":"10.1080/03014460.2023.2174272","DOIUrl":"https://doi.org/10.1080/03014460.2023.2174272","url":null,"abstract":"<p><strong>Background: </strong>The Bergen Growth Study 2 (BGS2) aims to characterise somatic and endocrine changes in healthy Norwegian children using a novel methodology.</p><p><strong>Subjects and methods: </strong>A cross-sectional sample of 1285 children aged 6-16 years was examined in 2016 using novel objective ultrasound assessments of breast developmental stages and testicular volume in addition to the traditional Tanner pubertal stages. Blood samples allowed for measurements of pubertal hormones, endocrine disruptive chemicals, and genetic analyses.</p><p><strong>Results: </strong>Ultrasound staging of breast development in girls showed a high degree of agreement within and between observers, and ultrasound measurement of testicular volume in boys also showed small intra- and interobserver differences. The median age was 10.4 years for Tanner B2 (pubertal onset) and 12.7 years for menarche. Norwegian boys reached a pubertal testicular volume at a mean age of 11.7 years. Continuous reference curves for testicular volume and sex hormones were constructed using the LMS method.</p><p><strong>Conclusions: </strong>Ultrasound-based assessments of puberty provided novel references for breast developmental stages and enabled the measurement of testicular volume on a continuous scale. Endocrine <i>z</i>-scores allowed for an intuitive interpretation of changing hormonal levels during puberty on a quantitative scale, which, in turn, provides opportunities for further analysis of pubertal development using machine-learning approaches.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9695405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of malnutrition among Samoan children aged 5 to 11 years in 2019-2020.","authors":"Courtney C Choy, Vaimoana Filipo Lupematasila, Maria Siulepa Arorae, Faatali Tafunaina, Folla Unasa, Christina Soti-Ulberg, Muagututia S Reupena, Rachel L Duckham, Kima Faasalele-Savusa, Take Naseri, Nicola L Hawley","doi":"10.1080/03014460.2023.2197298","DOIUrl":"10.1080/03014460.2023.2197298","url":null,"abstract":"<p><strong>Background: </strong>Globally, rapid economic development, urbanisation, and nutrition transitions have led to rising levels of malnutrition in all forms.</p><p><strong>Aim: </strong>The study objective was to document the prevalence of overweight/obesity, underweight, stunting, and anaemia among Samoan children in 2019-2020.</p><p><strong>Subjects and methods: </strong>Children from the <i>Ola Tuputupua'e</i> \"Growing Up\" in Samoa study at ages 5-11 years with complete physical assessments were included. Overweight/obesity, underweight, and stunting were classified using World Health Organisation Z-scores for body mass index-for-age (BMIZ> +1), weight-for-age (WAZ< -2SD), and height-for-age (HAZ< -2SD), respectively. Anaemia was defined as haemoglobin concentration <11.5 g/dL. Prevalence was compared by child age, sex, and census region of residence (representing urbanicity and exposure to nutrition transition) using Wilcoxon two-sample, Chi-square, or Fisher's exact tests.</p><p><strong>Results: </strong>The prevalence of overweight/obesity, underweight, stunting, and anaemia was 36.2%, 0.5%, 1.6%, and 31.6%, respectively. Overweight/obesity in children was positively associated with age and highly prevalent in periurban and urban regions. While children living in the rural region with the lowest exposure to nutrition transition had the highest prevalence of mild-to-moderate stunting, anaemia prevalence was lower compared to those in the urban region. No sex differences in malnutrition were observed.</p><p><strong>Conclusion: </strong>Moderate-to-high levels of overweight/obesity and anaemia call for comprehensive intervention strategies.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10214481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10292616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic association in <i>CYP3A4</i> and <i>CYP3A5</i> genes elevate the risk of prostate cancer.","authors":"Sm Faysal Bellah,&nbsp;Md Abdus Salam,&nbsp;S M Saker Billah,&nbsp;Md Rezaul Karim","doi":"10.1080/03014460.2023.2171122","DOIUrl":"https://doi.org/10.1080/03014460.2023.2171122","url":null,"abstract":"<p><strong>Background: </strong><i>CYP3A4</i> and <i>CYP3A5</i> are biologically potential genes responsible for prostate cancer.</p><p><strong>Aim: </strong>We aimed to analyse the expression and association of <i>CYP3A4</i> and <i>CYP3A5</i> genes in prostate cancer.</p><p><strong>Subjects and methods: </strong>Web-based bioinformatics tools were used to assess the association of <i>CYP3A4</i> and <i>CYP3A5</i> genes with prostate cancer risks. A case-control study of 210 prostate cancer cases and 207 controls was also approved to determine the allelic variants of the <i>CYP3A4</i> gene- rs2740574 (<i>CYP3A4*1B</i>) and the variant of <i>CYP3A5</i> gene-rs776746 (<i>CYP3A5*3</i>) using Polymerase Chain Reaction-Restriction Fragment Length Polymorphism (PCR-RFLP). The risk of prostate cancer was estimated as odds ratio (OR) and 95% confidence interval (CI) using unrestricted logistic regression models.</p><p><strong>Results: </strong>Our <i>in silico</i> data confirmed that both <i>CYP3A4</i> and <i>CYP3A5</i> genes are significantly associated with higher prostate cancer risks. In the case of <i>CYP3A4*1B</i> polymorphism, the heterozygote (*1 A/*1B), mutant (*1B/*1B), and combined heterozygote plus mutant (*1A/*1B+*1B/*1B) genotypes showed 3.52-fold, 3.90-fold, and 3.67-fold increased risk of prostate cancer, respectively. In the case of <i>CYP3A5*3</i> polymorphism, the heterozygote (*1/*3), mutant (*3/*3), and combined (*1/*3+*3/*3) genotypes were found to be significantly associated with 5.11-, 5.49-, and 5.28-fold greater risk of prostate cancer, respectively.</p><p><strong>Conclusion: </strong>Our results indicate that <i>CYP3A4*1B</i> and <i>CYP3A5*3</i> are significantly associated with increased prostate cancer risk.KEY MESSAGESBioinformatics tools were used and concluded that the <i>CYP3A4</i> and <i>CYP3A5</i> genes were significantly associated with the development and progression of prostate cancer.<i>CYP3A4</i> and <i>CYP3A5</i> polymorphisms were significantly associated with an increased risk of prostate cancer.Polymerase Chain Reaction (PCR)-Restriction Fragment Length Polymorphism (RFLP) was used to estimate polymorphisms of prostate cancer progression in the Bangladeshi population.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9161492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial: EAA and ISGA congress Vilnius 2022.","authors":"Noël Cameron","doi":"10.1080/03014460.2023.2259241","DOIUrl":"10.1080/03014460.2023.2259241","url":null,"abstract":"","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41162702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urbanisation and its associated factors affecting human gut microbiota: where are we heading to?","authors":"Farhat Abjani,&nbsp;Priya Madhavan,&nbsp;Pei Pei Chong,&nbsp;Karuthan Chinna,&nbsp;Charles Anthony Rhodes,&nbsp;Yvonne Ai Lian Lim","doi":"10.1080/03014460.2023.2170464","DOIUrl":"https://doi.org/10.1080/03014460.2023.2170464","url":null,"abstract":"<p><strong>Context: </strong>The continuous rise in urbanisation and its associated factors has been reflected in the structure of the human gut ecosystem.</p><p><strong>Objective: </strong>The main focus of this review is to discuss and summarise the major risk factors associated with urbanisation that affect human gut microbiota thus affecting human health.</p><p><strong>Methods: </strong>Multiple medical literature databases, namely PubMed, Google, Google Scholar, and Web of Science were used to find relevant materials for urbanisation and its major factors affecting human gut microbiota/microbiome. Both layman and Medical Subject Headings (MeSH) terms were used in the search. Due to the scarcity of the data, no limitation was set on the publication date. Relevant materials in the English language which include case reports, chapters of books, journal articles, online news reports and medical records were included in this review.</p><p><strong>Results: </strong>Based on the data discussed in the review, it is quite clear that urbanisation and its associated factors have long-standing effects on the human gut microbiota that result in alterations of gut microbial diversity and composition. This is a matter of serious concern as chronic inflammatory diseases are on the rise in urbanised societies.</p><p><strong>Conclusion: </strong>A better understanding of the factors associated with urbanisation will help us to identify and implement new biological and social approaches to prevent and treat diseases and improve health globally by deepening our understanding of these relationships and increasing studies across urbanisation gradients.HIGHLIGHTSHuman gut microbiota have been linked to almost every important function, including metabolism, intestinal homeostasis, immune system, biosynthesis of vitamins, brain processes, and behaviour.However, dysbiosis i.e., alteration in the composition and diversity of gut microbiota is associated with the pathogenesis of many chronic conditions.In the 21st century, urbanisation represents a major demographic shift in developed and developing countries.During this period of urbanisation, humans have been exposed to many environmental exposures, all of which have led to the dysbiosis of human gut microbiota.The main focus of the review is to discuss and summarise the major risk factors associated with urbanisation and how it affects the diversity and composition of gut microbiota which ultimately affects human health.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9209130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population data and phylogenetic analysis of 37 Y-STR loci in the Hui population from Yunnan Province, Southwest China.","authors":"Xiufeng Zhang,&nbsp;Kunya Li,&nbsp;Yifan Duan","doi":"10.1080/03014460.2023.2188258","DOIUrl":"https://doi.org/10.1080/03014460.2023.2188258","url":null,"abstract":"<p><strong>Background: </strong>Previous studies of the genetic polymorphism of the Y-chromosomal short tandem repeat (Y-STR) of Huis were focussed on the northwest of China. However, the population genetic characteristics of Chinese Hui residing in Yunnan province, Southwest China, remain unclear.</p><p><strong>Aim: </strong>To provide genetic data for 37 Y-STRs in the Chinese Hui population of Yunnan province, as well as to investigate population genetic relationships between the Chinese Hui and another 26 populations from China and neighbouring countries.</p><p><strong>Subjects and methods: </strong>In total, 326 unrelated healthy male individuals were genotyped using the Goldeneye^TM Y Plus PCR Amplification Kit. Genetic relationships between different populations were analysed using YHRD's AMOVA tools.</p><p><strong>Results: </strong>A total of 279 haplotypes were detected, out of which 244 were unique. The overall haplotype diversity (HD) and discrimination capacity (DC) were 0.9989 and 0.8611, respectively. The gene diversity (GD) ranged from 0.0544 (DYS645) to 0.9656 (DYS385).</p><p><strong>Conclusions: </strong>The population comparison indicated that Muslim populations (Hui, Salar and Uighur) showed significantly more genetic affinity than other populations. Our results could be applied in forensic practice and population genetic studies.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9853931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic analysis of 23 Y-STR loci in the Va population from Yunnan Province, Southwest China.","authors":"Jing Yuan,&nbsp;Lei Huang,&nbsp;Yuan Yin,&nbsp;Xiufeng Zhang","doi":"10.1080/03014460.2023.2197654","DOIUrl":"https://doi.org/10.1080/03014460.2023.2197654","url":null,"abstract":"<p><strong>Background: </strong>Y-chromosomal short tandem repeat (Y-STR) polymorphisms are widely used in forensic DNA analysis. However, there is a lack of information about the Chinese Va population in the Y-STR Haplotype Reference Database.</p><p><strong>Aim: </strong>To establish the Y-chromosome Haplotype Reference Database of the Yunnan Va population and investigate the population genetic relationships with other geographically adjacent groups.</p><p><strong>Subjects and methods: </strong>In total, 23 Y-STR loci were genotyped with the PowerPlex Y23 Kit in 368 unrelated healthy Va males from Yunnan Province, Southwest China. Genetic polymorphism was analysed using the YHRD's AMOVA tools and the MEGA 6.0 software.</p><p><strong>Results: </strong>The gene diversity (GD) of the 23 Y-STR loci ranged from 0.3092 (DYS19) to 0.7868 (DYS385a/b). According to haplotype analysis, 204 different haplotypes were obtained, out of which 144 were unique. The haplotype diversity (HD) and discrimination capacity (DC) were 0.9852 and 0.5543, respectively. By comparing the Yunnan Va group with the other 22 referential groups, the results revealed that Yunnan Va was isolated from other groups.</p><p><strong>Conclusions: </strong>The 23 Y-STR loci were highly polymorphic and informative in the Yunnan Va population, and the results enriched the basic genetic information for forensic investigation and population genetic studies.</p>","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":null,"pages":null},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}