Annals of Human Biology最新文献_第10页

The Nick Norgan Award 2023. 2023 年尼克-诺根奖

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 Epub Date: 2024-01-10 DOI: 10.1080/03014460.2023.2298113

Rachel Deevey

引用次数: 0

Cadmium exposure is associated with chronic kidney disease in a superfund site lead smelter community in Dallas, Texas. 在德克萨斯州达拉斯市的一个铅冶炼厂社区，镉暴露与慢性肾病有关。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 DOI: 10.1080/03014460.2023.2236017

Bert B Little, Giang T Vu, Brad Walsh

{"title":"Cadmium exposure is associated with chronic kidney disease in a superfund site lead smelter community in Dallas, Texas.","authors":"Bert B Little, Giang T Vu, Brad Walsh","doi":"10.1080/03014460.2023.2236017","DOIUrl":"https://doi.org/10.1080/03014460.2023.2236017","url":null,"abstract":"Background: The study was conducted in a Dallas lead smelter community following an Environmental Protection Agency (EPA) Superfund Cleanup project. Lead smelters operated in the Dallas community since the mid-1930s.Aim: To test the hypothesis that cadmium (Cd) exposure is associated with chronic kidney disease (CKD) ≥ stage 3.Subjects and methods: Subjects were African American residents aged ≥19 to ≤ 89 years (n=835). CKD ≥ stage 3 was predicted by blood Cd concentration with covariates.Results: In logistic regression analysis, CKD ≥ stage 3 was predicted by age ≥ 50 years (OR = 4.41, p < 0.0001), Cd level (OR = 1.89, p < .05), hypertension (OR = 3.15, p < 0.03), decades living in the community (OR = 1.34, p < 0.003) and T2DM (OR = 2.51, p < 0.01). Meta-analysis of 11 studies of Cd and CKD ≥ stage 3 yielded an ORRANDOM of 1.40 (p < 0.0001). Chronic environmental Cd exposure is associated with CKD ≥ stage 3 in a Dallas lead smelter community controlling covariates.Conclusion: Public health implications include screening for heavy metals including Cd, cleanup efforts to remove Cd from the environment and treating CKD with newer renal-sparing medications (e.g., SGLT-2 inhibitors, GLP-1s).","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"360-369"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10442624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The association between daytime sleep and general obesity risk differs by sleep duration in Iranian adults. 在伊朗成年人中，白天睡眠与一般肥胖风险之间的关系因睡眠时长而异。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 DOI: 10.1080/03014460.2023.2213479

Noushin Mohammadifard, Firoozeh Sajjadi, Fahimeh Haghighatdoost, Soraya Masoodi, Masoumeh Sadeghi, Hamidreza Roohafza, Maryam Maghroun, Hassan Alikhasi, Farzaneh Zamaneh, Parisa Zakeri, Simin Karimi, Nizal Sarrafzadegan

{"title":"The association between daytime sleep and general obesity risk differs by sleep duration in Iranian adults.","authors":"Noushin Mohammadifard, Firoozeh Sajjadi, Fahimeh Haghighatdoost, Soraya Masoodi, Masoumeh Sadeghi, Hamidreza Roohafza, Maryam Maghroun, Hassan Alikhasi, Farzaneh Zamaneh, Parisa Zakeri, Simin Karimi, Nizal Sarrafzadegan","doi":"10.1080/03014460.2023.2213479","DOIUrl":"https://doi.org/10.1080/03014460.2023.2213479","url":null,"abstract":"Background: Sleep duration and daytime napping and obesity are related to adiposity; however, it is not clear whether the association between daytime napping and adiposity measures can differ by sleep duration.Aim: To clarify the association between daytime napping and general and abdominal obesity based on sleep duration of participants.Subjects and methods: This cross-sectional study was conducted on 1,683 individuals (837 men and 846 women) aged ≥ 35 years. Height, weight and waist circumference (WC) were measured according to the standard protocols. Body mass index (BMI) was calculated. Self-reported sleep duration (in a 24-hour cycle) was recorded. The odds of general and abdominal obesity were compared between nappers and non-nappers, stratified by their sleep duration (≤ 6 h, 6-8 h, ≥ 8 h).Results: The mean (SD) age of participants was 47.48 ± 9.35 years. Nappers with a short sleep duration (≤ 6 h) had greater BMI and higher risk for overweight/obesity compared with counterpart non-nappers after adjustment for potential confounders (OR = 1.61, 95% CI = 1.07-2.41). In subjects with moderate sleep duration (6-8 h), nappers had a tendency towards higher BMI in comparison with non-nappers (28.04 ± 0.25 vs. 26.93 ± 0.51 kg/m2; p = 0.05), however, no significant difference was observed for the risk of obesity. Daytime napping was not related to the risk of obesity in long sleepers. No significant association was observed for abdominal obesity measures.Conclusions: Daytime napping is associated with increased risk of overweight/obesity in short sleepers. However, in subjects with longer sleep duration, it is not related to the risk of overweight/obesity.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"211-218"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9574499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Haplotypic polymorphisms and forensic applications in Chinese Hunan Han population based on a series of Y-STR loci: a perspective of paternal inheritance. 基于一系列Y-STR位点的中国湖南汉族人群单倍型多态性及其法医学应用:父系遗传的视角

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 DOI: 10.1080/03014460.2023.2171120

Ming Zhao, Wei Cui, Yunying Zhang, Qiong Lan, Bofeng Zhu

{"title":"Haplotypic polymorphisms and forensic applications in Chinese Hunan Han population based on a series of Y-STR loci: a perspective of paternal inheritance.","authors":"Ming Zhao, Wei Cui, Yunying Zhang, Qiong Lan, Bofeng Zhu","doi":"10.1080/03014460.2023.2171120","DOIUrl":"https://doi.org/10.1080/03014460.2023.2171120","url":null,"abstract":"Background: Hunan, a multinational province in China, possesses more than fifty ethnic groups, such as the Han, Yao, Tujia, Miao, and so on.Aims: To evaluate the forensic efficiency of the novel panel and investigate the genetic relationships between Hunan Han population and 12 other reference populations from China.Subjects and methods: Haplotypic data of 153 unrelated males of Hunan Han population were investigated using the AGCU Y SUPP Plus amplification system containing 27 Y-chromosomal short tandem repeat (STR) loci. Forensic parameters were calculated to evaluate the application efficiency of this panel in Hunan Han population.Results: Haplotype diversity, discrimination capability, and match probability values were 0.9999999977, 1.0000, and 0.0065, respectively. Pairwise fixation index values demonstrated that the minimal genetic differentiation (0.0073) was found between Hunan Han population and Hunan Yao group, while the maximal genetic differentiation (0.0651) was observed between Hunan Han and Guangxi Yao group from the perspective of the patrilineal DNA analysis.Conclusions: The haplotype distributions of 27 Y-STR loci in Hunan Han population exhibited remarkable polymorphisms. Moreover, this panel has potential advantages for the forensic applications regarding family investigations, paternity testing of the paternal line, and population genetics.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"52-55"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10855147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic polymorphisms and phylogenetic characteristics of Tibeto-Burman-speaking Lahu population from southwest China based on 41 Y-STR loci. 基于41个Y-STR位点的中国西南藏缅语系拉祜族群体遗传多态性及系统发育特征

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 DOI: 10.1080/03014460.2023.2171123

Chongchong Xu, Wei Wei, Mingxin Zuo, Wu Zuo, Kuan Li, Xinqing Lian, Shixu Wang, Xuemei Zhou, Xiufeng Zhang, Shurong Zhong

{"title":"Genetic polymorphisms and phylogenetic characteristics of Tibeto-Burman-speaking Lahu population from southwest China based on 41 Y-STR loci.","authors":"Chongchong Xu, Wei Wei, Mingxin Zuo, Wu Zuo, Kuan Li, Xinqing Lian, Shixu Wang, Xuemei Zhou, Xiufeng Zhang, Shurong Zhong","doi":"10.1080/03014460.2023.2171123","DOIUrl":"https://doi.org/10.1080/03014460.2023.2171123","url":null,"abstract":"Background: Male sex-linked Y-chromosome short tandem repeats (Y-STRs) have been widely used in forensic cases and population genetics research. At present, the forensic-related Y-STR data in the Chinese Lahu population are still poorly understood.Aim: To enrich the available Y-STR data of this Chinese minority population and investigate its phylogenetic relationships with other reported populations.Subjects and methods: The genetic polymorphisms of 41 Y-STR loci were analysed in 299 unrelated healthy Lahu male individuals from Southwest China. Phylogenetic analyses were performed by multidimensional scaling analysis and neighbor-joining phylogenetic tree construction.Results: A total of 379 alleles were observed at the 41 Y-STR loci. The allele frequencies ranged from 0.0033 to 0.9666. The genetic diversity values ranged from 0.0653 to 0.9072. A total of 254 different haplotypes of the 41 Y-STR loci were observed in 299 individuals. The values of haplotype diversity, haplotype match probability, and discrimination capacity were 0.9987, 0.0047, and 0.8495, respectively. The phylogenetic analysis indicated that the Tibeto-Burman-speaking Lahu population showed a close genetic relationship with the Yunnan Yi population.Conclusions: The haplotype data of the present study can enrich the forensic databases of this Chinese minority population and will be useful for population genetics and forensic DNA application.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"75-81"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10855149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Unveiling genetic diversity and forensic utility of SureID® human DNA identification kits: a comprehensive analysis of 44 autosomal STR loci in English and Irish populations. 揭示SureID®人类DNA鉴定试剂盒的遗传多样性和法医实用性：对英国和爱尔兰人群中44个常染色体STR基因座的综合分析。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 Epub Date: 2023-10-10 DOI: 10.1080/03014460.2023.2265814

Sasitaran Iyavoo, Jessica Perry, Simon Knights, Michalis Mavrommatis, Tatiana Petrova, Abigail Bevan, Stephen Cummings, Sharlize Pedroza Matute, Danlu Song, Thomas Haizel

{"title":"Unveiling genetic diversity and forensic utility of SureID® human DNA identification kits: a comprehensive analysis of 44 autosomal STR loci in English and Irish populations.","authors":"Sasitaran Iyavoo, Jessica Perry, Simon Knights, Michalis Mavrommatis, Tatiana Petrova, Abigail Bevan, Stephen Cummings, Sharlize Pedroza Matute, Danlu Song, Thomas Haizel","doi":"10.1080/03014460.2023.2265814","DOIUrl":"10.1080/03014460.2023.2265814","url":null,"abstract":"Background: Human identification and kinship testing in forensic science rely on Short Tandem Repeat (STR) multiplex kits, typically containing loci recommended by standard sets. However, complementary kits with additional STR loci can be valuable in complex cases. Allele frequency databases specific to the population are essential for accurate forensic analysis.Aim: This study aimed to generate allele frequencies and population genetic data for 44 autosomal STR loci from SureID® PanGlobal and 27comp kits in English and Irish populations for forensic casework, human identification, and kinship testing.Subjects and methods: Buccal swab samples from 645 White Caucasians (365 English, 280 Irish) were collected. DNA was extracted and amplified using the mentioned kits. Quality control, statistical analysis, and genetic distance calculations were performed.Results: Both kits demonstrated robustness with no significant deviations from Hardy-Weinberg Equilibrium (HWE). Variant alleles and minor discordances between kits were observed. Syntenic STR pairs were identified but showed no significant linkage. A close genetic relationship was found between English and Irish populations, allowing for combined databases.Conclusions: The SureID® PanGlobal and 27comp kits showed high discriminatory power and reliability in the English and Irish populations. Care is needed when handling variant alleles, discordances, and syntenic loci. Combining data from both populations is feasible for a comprehensive database. Further studies are required to explore their effectiveness in diverse populations.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"399-406"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41184101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioinformatics analysis of the potential mechanisms of Alzheimer's disease induced by exposure to combined triazine herbicides. 接触三嗪类除草剂诱发阿尔茨海默病潜在机制的生物信息学分析。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 Epub Date: 2023-10-11 DOI: 10.1080/03014460.2023.2259242

Jianan Li, Ling Qi, Yuxin Chen, Haoming Lv, Haoran Bi

{"title":"Bioinformatics analysis of the potential mechanisms of Alzheimer's disease induced by exposure to combined triazine herbicides.","authors":"Jianan Li, Ling Qi, Yuxin Chen, Haoming Lv, Haoran Bi","doi":"10.1080/03014460.2023.2259242","DOIUrl":"10.1080/03014460.2023.2259242","url":null,"abstract":"Background: The development of Alzheimer's disease (AD) is promoted by a combination of genetic and environmental factors. Notably, combined exposure to triazine herbicides atrazine (ATR), simazine (SIM), and propazine (PRO) may promote the development of AD, but the mechanism is unknown.Aim: To study the molecular mechanism of AD induced by triazine herbicides.Methods: Differentially expressed genes (DEGs) of AD patients and controls were identified. The intersectional targets of ATR, SIM, and PRO for possible associations with AD were screened through network pharmacology and used for gene ontology (GO) and Kyoto Encyclopaedia of Genes and Genomes (KEGG) enrichment analysis. The binding potentials between the core targets and herbicides were validated by molecular docking and molecular dynamics.Results: A total of 1,062 DEGs were screened between the AD patients and controls, which identified 148 intersectional targets of herbicides causing AD that were screened by network pharmacology analysis. GO and KEGG enrichment analysis revealed that cell cycling and cellular senescence were important signalling pathways. Finally, the core targets EGFR, FN1, and TYMS were screened and validated by molecular docking and molecular dynamics.Conclusion: Our results suggest that combined exposure to triazine herbicides might promote the development of AD, thereby providing new insights for the prevention of AD.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"442-451"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of orthodontic treatment on masticatory muscles activity: a meta-analysis. 正畸治疗对咀嚼肌活动的影响：一项荟萃分析。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 Epub Date: 2023-11-06 DOI: 10.1080/03014460.2023.2271840

Yuxiang Zhan, Minjie Yang, Shuoqiu Bai, Siqin Zhang, Yunqin Huang, Fansheng Gong, Xiaolin Nong

{"title":"Effects of orthodontic treatment on masticatory muscles activity: a meta-analysis.","authors":"Yuxiang Zhan, Minjie Yang, Shuoqiu Bai, Siqin Zhang, Yunqin Huang, Fansheng Gong, Xiaolin Nong","doi":"10.1080/03014460.2023.2271840","DOIUrl":"https://doi.org/10.1080/03014460.2023.2271840","url":null,"abstract":"Context: A comprehensive meta-analysis was carried out to investigate the impact of orthodontics on masticatory muscles.Methods: A thorough search of various databases, including CNKI, Wan Fang, VIP, CBM, MEDLINE, PubMed, Cochrane Library, EMBASE, Web of Science, and Google Scholar, was performed to identify relevant studies on patients undergoing orthodontics or functional corrections. Six case-control studies were finally included in this analysis, which specifically examined the effect of orthodontic treatment on masticatory muscle function.Results: The results revealed that the mean masticatory muscle voltage in patients treated with orthodontics was found to be higher after treatment compared to before treatment [odds ratio (OR)=1.57, 95% confidence interval (CI) (0.57, 2.57), p = 0.002], which could potentially have an impact on masticatory muscle function, particularly in individuals with Class II Division 1 malocclusion.Conclusion: These findings contribute to our understanding of the effects of orthodontic interventions on masticatory muscles, further highlighting the importance of orthodontics in optimising masticatory function.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"465-471"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71488504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Population genetic analysis of 12 X-STR markers in Slovakia. 斯洛伐克12个X-STR标记的群体遗传分析。

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 Epub Date: 2023-10-09 DOI: 10.1080/03014460.2023.2264769

Zdenko Červenák, Filip Červenák, Andrej Choma, Marián Baldovič, Soňa Masnicová

{"title":"Population genetic analysis of 12 X-STR markers in Slovakia.","authors":"Zdenko Červenák, Filip Červenák, Andrej Choma, Marián Baldovič, Soňa Masnicová","doi":"10.1080/03014460.2023.2264769","DOIUrl":"10.1080/03014460.2023.2264769","url":null,"abstract":"Background: During the last 20 years, X-chromosomal STR markers have become widely used in forensic genetics and paternity testing. Nevertheless, to exploit their full potential in any given population, a reliable reference dataset needs to be established. Since no relevant studies concerning these markers have been performed on the Slovak population so far, we decided to analyse several commonly used markers in this population.Aim: To create an informative set of Slovak population data concerning X-STR markers.Subjects and methods: We genotyped 378 individuals and analysed 12 loci (DXS10148, DX10135, DXS8378, DXS7132, DXS10079, DXS10074, DXS10103, HPRTB, DXS10101, DXS10146, DXS10134 and DXS742) localised in four distinct linkage groups.Results: Our analysis showed that the most informative marker is DXS10135 (PIC = 0,927) and the most informative linkage group (LG) is LG1 with 149 different haplotypes. This analysis also confirmed linkage disequilibrium for two pairs of markers (DX10101-DX10103 and DX10101-HPRTB) within LG3 in female samples. No statistically significant departure from HWE was observed for any locus. Moreover, the interpopulation comparison of 8 European populations based on haplotype frequencies showed no statistically significant FST values in any LG, except for LG2 in comparison with the German population.Conclusion: We created a haplotype database for forensic analyses and kinship testing in Slovakia, as well as the CE dataset which can be used to further increase the decision power in similar analyses in the future.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"431-435"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41168761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Forensic characterisation and polymorphism analysis of 16 X-chromosomal STRs in the Jining Han population in Eastern China. 中国东部济宁汉族人群16个x染色体STRs的法医学特征及多态性分析

IF 1.7 4区医学

Annals of Human Biology Pub Date : 2023-02-01 DOI: 10.1080/03014460.2023.2213478

Yequan Wang, Ao Gao, Xiudi Hou, Qi Liu, Dan Wang, Zhen Dang

{"title":"Forensic characterisation and polymorphism analysis of 16 X-chromosomal STRs in the Jining Han population in Eastern China.","authors":"Yequan Wang, Ao Gao, Xiudi Hou, Qi Liu, Dan Wang, Zhen Dang","doi":"10.1080/03014460.2023.2213478","DOIUrl":"https://doi.org/10.1080/03014460.2023.2213478","url":null,"abstract":"Background: X-chromosomal short tandem repeats (X-STRs) are a useful supplementary approach to analysing autosomal markers in forensics and kinship studies; such markers are not well-characterised in many populations.Aim: To investigate population genetic polymorphism and forensic characterisation of 16 X-STRs in the Jining Han population, and analyse genetic relationships with other Chinese populations.Subjects and methods: Allele frequencies for 16 X-STR loci were obtained from a sample set of 527 unrelated individuals from the Jining Han population. Population genetic analyses of Jining Han and another 10 reference populations were conducted using phylogenetic tree, principal component analysis and multidimensional scaling.Results: We detected 149 alleles, with frequencies ranging from 0.0013 to 0.8242. The combined powers of discrimination in males and females were 0.999999997194774 and 0.999999999999995, respectively. The combined mean exclusion change (MEC)Krüger, MECKishida, MECDesmarais, and MECDesmarais Duos values were 0.999974632649096, 0.999999976997582, 0.999999977013201, and 0.999993755768423, respectively. We detected relatively high genetic homogeneity in populations with similar ethnic or geographic origins, and a close relationship between the Jining Han and Beijing Han populations.Conclusions: The present findings indicate that the 16 X-STR loci examined are highly polymorphic in the Han population of Jining, providing useful information for forensic science and population genetics studies.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"50 1","pages":"351-355"},"PeriodicalIF":1.7,"publicationDate":"2023-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10158685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0