Annals of Human Biology最新文献_第4页

Associations between growth, maturation and non-contact injury risk in Scottish male academy football: a prospective multi-academy study. 苏格兰男子足球学院的成长、成熟和非接触性损伤风险之间的关系：一项前瞻性的多学院研究。

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-06-02 DOI: 10.1080/03014460.2026.2673847

Steven Curnyn, Mark Leslie, Sean Cumming, Debbie Palmer, Sean Williams

{"title":"Associations between growth, maturation and non-contact injury risk in Scottish male academy football: a prospective multi-academy study.","authors":"Steven Curnyn, Mark Leslie, Sean Cumming, Debbie Palmer, Sean Williams","doi":"10.1080/03014460.2026.2673847","DOIUrl":"10.1080/03014460.2026.2673847","url":null,"abstract":"Background: Biological maturation significantly influences injury risk in youth footballers, yet evidence from male Scottish academies remains limited. Variability in maturity timing means players do not reach peak height velocity (PHV) at the same chronological age, potentially creating disparities in injury vulnerability within age-grouped squads.Aim: To investigate the relationship between biological maturation, growth, and non-contact injury risk in male academy football players.Subjects and methods: A prospective cohort study was conducted across five Club Academy Scotland (CAS) academies during the 2024-2025 season, including 392 male players aged 9-17 years (U10-U18). Anthropometric assessments were performed quarterly to estimate growth rate and biological maturity status (pre-, circa-, and post-PHV) and timing (early-, on-time-, and late-maturing) using percentage of predicted adult height (%PAH). Non-contact injury incidence (per 1000 h) and burden (days lost per 1000 h) were recorded throughout the season.Results: Injury incidence was highest in post-PHV players, as well as in early- and late-maturing individuals. A non-linear relationship was observed between %PAH and injury incidence, with dual peaks at approximately 90% and 100% PAH, corresponding to circa- and post-PHV periods. Growth velocity was positively associated with injury incidence, with a marked increase observed at rates exceeding 10 cm/year.Conclusions: These findings highlight the importance of monitoring growth and maturation in academy football and support the implementation of individualised, maturity-informed approaches to load management to mitigate injury risk.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2673847"},"PeriodicalIF":1.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The challenges of optimising the treatment of children diagnosed with idiopathic short stature. 优化特发性矮小儿童治疗的挑战。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-02-06 DOI: 10.1080/03014460.2026.2621718

Christopher J Romero, Robert Rapaport

引用次数: 0

Association between body roundness index and asthma in children and adolescents: findings from NHANES 1999-2020. 儿童和青少年身体圆度指数与哮喘之间的关系：NHANES 1999-2020的研究结果

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-08-06 DOI: 10.1080/03014460.2026.2705281

Tingqiaonan Chen, Shujing Cai, Huiqin Wang

{"title":"Association between body roundness index and asthma in children and adolescents: findings from NHANES 1999-2020.","authors":"Tingqiaonan Chen, Shujing Cai, Huiqin Wang","doi":"10.1080/03014460.2026.2705281","DOIUrl":"https://doi.org/10.1080/03014460.2026.2705281","url":null,"abstract":"Background: Childhood and adolescent asthma remains a major public health concern, and obesity may contribute through mechanical and inflammatory pathways. The Body Roundness Index (BRI), derived from waist circumference and height, may better reflect central adiposity than general body-size measures.Aim: To investigate the association between BRI and asthma in children and adolescents.Subjects and methods: A total of 28,789 National Health and Nutrition Examination Survey (NHANES) 1999-2020 participants aged 6-20 years were included. Current asthma was identified using questionnaire data. BRI, calculated from waist circumference and height, was used as the primary exposure. Weighted multivariable logistic regression models were used to examine the association between BRI and current asthma, and restricted cubic spline (RCS) models were applied to assess potential nonlinear associations. Subgroup and sensitivity analyses were performed to assess the robustness of the findings. Weighted receiver operating characteristic (ROC) analyses were used to compare the predictive abilities of BRI and Body Mass Index (BMI) z-score in fully adjusted models.Results: Higher BRI was associated with higher odds of current asthma (OR = 1.233, 95% CI:1.158-1.313, p < 0.001). RCS analysis suggested a nonlinear association between BRI and current asthma. In fully adjusted analyses, BRI and BMI z score showed comparable discriminative performance, with no significant difference in the area under the curve.Conclusions: Higher BRI was positively associated with current asthma among children and adolescents. Future prospective studies are warranted to clarify the temporal relationship and underlying biological mechanisms.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2705281"},"PeriodicalIF":1.8,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148681034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body composition phenotyping of obesity in children aged 6-18 years: multi-strategy clustering and interpretable machine learning. 6-18岁儿童肥胖的身体成分表型：多策略聚类和可解释的机器学习。

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-06-03 DOI: 10.1080/03014460.2026.2661592

Yuhang Wang, Shuang Shi, Jin Cai

{"title":"Body composition phenotyping of obesity in children aged 6-18 years: multi-strategy clustering and interpretable machine learning.","authors":"Yuhang Wang, Shuang Shi, Jin Cai","doi":"10.1080/03014460.2026.2661592","DOIUrl":"10.1080/03014460.2026.2661592","url":null,"abstract":"Background: Body composition heterogeneity in childhood obesity is not fully captured by BMI, motivating operational phenotyping using non-invasive measures.Aim: To identify body composition-based phenotypes of obesity in children aged 6-18 years using complementary clustering approaches and characterise their discriminative structure through interpretable machine learning.Subjects and methods: We enrolled 78 obese children (6-18 years) from a single-centre outpatient clinic in a cross-sectional design. Thirteen BIA-derived indices were Z-standardised and analysed using parallel unsupervised strategies (PCA-K-means, HCPC, UMAP-DBSCAN). Cluster quality, stability, and agreement were evaluated by mean silhouette, Jaccard bootstrap (100 resamples), and adjusted Rand index (ARI). Separability was assessed with a random forest classifier using five-fold cross-validation (out-of-fold accuracy; macro/micro AUC), with SHAP for interpretability.Results: Four phenotypes were consistently supported: low-fat/high-muscle, balanced, high-fat/low-muscle, and mixed high-fat/high-muscle. Cross-validated performance was 85.9% accuracy, macro AUC 0.953, and micro AUC 0.965. Structural metrics were silhouette 0.41 and ARI 0.94, with cluster-wise Jaccard 0.789/0.812/0.835/0.858 (range 0.78-0.86). SHAP prioritised fat mass and BMI; BIA-derived basal metabolic indices contributed as device-estimated outputs, while lean mass and skeletal muscle mass showed opposing contributions.Conclusions: This exploratory, single-centre framework is hypothesis-generating and requires external validation with outcome-linked markers and imaging before any clinical applicability is considered.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2661592"},"PeriodicalIF":1.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular epidemiology of the MTHFR C677T polymorphism and its association with type 2 diabetes mellitus at the University of Gondar Comprehensive Specialized Hospital. 贡达尔大学综合专科医院MTHFR C677T多态性的分子流行病学及其与2型糖尿病的关系

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2026-12-01 Epub Date: 2026-03-16 DOI: 10.1080/03014460.2026.2632816

Genetu Kassahun Berie, Mequanente Dagnaw, Meera Indracanti, Muluken Dejen, Nega Berhane

{"title":"Molecular epidemiology of the MTHFR C677T polymorphism and its association with type 2 diabetes mellitus at the University of Gondar Comprehensive Specialized Hospital.","authors":"Genetu Kassahun Berie, Mequanente Dagnaw, Meera Indracanti, Muluken Dejen, Nega Berhane","doi":"10.1080/03014460.2026.2632816","DOIUrl":"10.1080/03014460.2026.2632816","url":null,"abstract":"Background: Type 2 diabetes mellitus (T2DM) is marked by chronic hyperglycemia from impaired insulin secretion and action. The MTHFR C677T variant, affecting folate metabolism and homocysteine, has been linked to T2DM, though evidence is inconsistent, especially in Ethiopia.Aim: The objective of this study was to investigate the association of MTHFR C677T gene polymorphism and the risk of T2DM among patients treated at the University of Gondar Comprehensive Specialized Hospital.Subjects and methods: A comparative cross-sectional study of 140 T2DM patients and 140 controls used non-random purposive sampling. Data included sociodemographic and lifestyle factors, clinical exams, and PCR-RFLP detection of the MTHFR C677T polymorphism. Analysis used chi-square and logistic regression. Results are reported as OR with 95% CI; p < 0.05 was significant.Results: Individuals aged 30-44 and 45-59 had higher T2DM odds than those 18-29. Other risks were high blood pressure, family history, alcohol use, and smoking. Underweight showed higher but non-significant risk. MTHFR C677T was associated, with CT and TT increasing susceptibility vs CC. Vegetable intake and physical activity were not significant.Conclusion: The study highlights integrating genetic profiling with targeted risk reduction. At-risk patients should adopt healthy lifestyles, undergo individualized T2DM screening, and avoid smoking and excess alcohol. Health facilities should strengthen screening and genetic counseling, with support from policymakers, researchers, NGOs, and community groups.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"53 1","pages":"2632816"},"PeriodicalIF":1.3,"publicationDate":"2026-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The wintertime brown adipose tissue thermogenesis of New York City residents amidst climate change. 气候变化下纽约市居民的冬季棕色脂肪组织产热。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2025-12-01 Epub Date: 2025-02-12 DOI: 10.1080/03014460.2025.2455685

Stephanie B Levy, Shelby Pirtle, Ruthbernick Bastien, Kandra Cruz, Jahnae Vernon

{"title":"The wintertime brown adipose tissue thermogenesis of New York City residents amidst climate change.","authors":"Stephanie B Levy, Shelby Pirtle, Ruthbernick Bastien, Kandra Cruz, Jahnae Vernon","doi":"10.1080/03014460.2025.2455685","DOIUrl":"10.1080/03014460.2025.2455685","url":null,"abstract":"Background: The built environment buffers residents of large cities, such as New York (NYC), from exposure to low temperatures. Furthermore, average winter temperatures are rising in NYC due to climate change. The degree to which NYC residents exhibit metabolic adaptations to cold stress is currently unclear.Aim: This study quantified variation in brown adipose tissue (BAT), energy expenditure (EE), and ambient temperature among NYC residents.Subjects and methods: We recruited 46 adults (31 females; 15 males) and quantified anthropometrics, change in EE, and BAT thermogenesis after a cooling condition in the lab. A subsample of 21 participants wore temperature loggers for three days in order to quantify ambient temperature exposure.Results: BAT thermogenesis was not significantly associated with change in EE. Participants that were exposed to lower average temperatures exhibited greater BAT thermogenesis (p = 0.013). Change in EE, however, was not significantly associated with time spent outside nor average temperature exposure.Conclusion: Our study provides mixed evidence for the role of BAT thermogenesis in metabolic adaptations to cold stress among NYC residents. Many young adults in NYC are exposed to minimal amounts of cold stress, and this trend is likely to be exacerbated by climate change.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2455685"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pliocene climatic change and the origins of Homo at Ledi-Geraru, Ethiopia. 上新世气候变化与埃塞俄比亚勒迪-杰拉鲁人属的起源。

IF 1.2 4区医学

Annals of Human Biology Pub Date : 2025-12-01 Epub Date: 2025-02-27 DOI: 10.1080/03014460.2025.2462255

Irene E Smail, Amy L Rector, Joshua R Robinson, Kaye E Reed

{"title":"Pliocene climatic change and the origins of Homo at Ledi-Geraru, Ethiopia.","authors":"Irene E Smail, Amy L Rector, Joshua R Robinson, Kaye E Reed","doi":"10.1080/03014460.2025.2462255","DOIUrl":"10.1080/03014460.2025.2462255","url":null,"abstract":"Background: Long-term cooling and aridification are associated with the spread of grassland habitats and the appearance of new hominin adaptations starting in the late Miocene. However, limited fossil data during critical periods limits our ability to examine these climatic correlations further.Aim: We set out to reconstruct potential habitat and climate conditions at the origin of our genus Homo.Subjects and methods: Mammalian faunal lists and species trait data were collected for Ledi-Geraru localities dated from ∼2.78 to <2.59 million years ago (Ma). These were compared to a modern comparative dataset of mammal communities across Africa with known habitat and climate conditions, as well as to other fossil mammal data from eastern Africa in the time period leading up to and following shortly after the earliest known appearance of Homo at ∼2.78 Ma.Results: Early Homo is associated with ongoing aridification and increasing seasonality in the Afar Depression. While climate trends in eastern Africa parallel global models, local environmental variation persisted across fossil-bearing regions.Conclusion: Climatic change (aridification and increasing seasonality) continues to be supported as a possible factor in the origins of our genus, although other fossil hominins continued to persist in these conditions.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2462255"},"PeriodicalIF":1.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Human biology, climate change and sustainability. 人类生物学，气候变化和可持续性。

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2025-12-01 Epub Date: 2025-09-02 DOI: 10.1080/03014460.2025.2544447

Noël Cameron

引用次数: 0

Whose health? Whose truth? Navigating the "Make America Healthy Again" - public health divide. 他健康吗?谁的真理?引导“让美国再次健康”——公共卫生鸿沟。

IF 1.3 4区医学

Annals of Human Biology Pub Date : 2025-12-01 Epub Date: 2025-10-05 DOI: 10.1080/03014460.2025.2565489

Nicola L Hawley

引用次数: 0

Ambient temperature and wet bulb globe temperature outperform heat index in predicting hydration status and heat perception in a semi-arid environment. 环境温度和湿球温度优于热指数在预测水化状态和热感知在半干旱环境。

IF 1.8 4区医学

Annals of Human Biology Pub Date : 2025-12-01 Epub Date: 2025-02-24 DOI: 10.1080/03014460.2025.2456152

Lilian Baker, Hannah Jacobson, Amanda McGrosky, Elena Hinz, Faith Wambua, Alison Sherwood, Tiffany-Chrissy Mbeng, Rosemary Nzunza, David R Braun, Emmanuel Ndiema, Herman Pontzer, Asher Y Rosinger

{"title":"Ambient temperature and wet bulb globe temperature outperform heat index in predicting hydration status and heat perception in a semi-arid environment.","authors":"Lilian Baker, Hannah Jacobson, Amanda McGrosky, Elena Hinz, Faith Wambua, Alison Sherwood, Tiffany-Chrissy Mbeng, Rosemary Nzunza, David R Braun, Emmanuel Ndiema, Herman Pontzer, Asher Y Rosinger","doi":"10.1080/03014460.2025.2456152","DOIUrl":"10.1080/03014460.2025.2456152","url":null,"abstract":"Background: Climate change is increasing temperatures, frequency of heatwaves, and erratic rainfall, which threatens human biology and health, particularly in already extreme environments. Therefore, it is important to understand how environmental heat stress measures are tied to human water needs and thermoregulation under increasingly hot conditions.Aim: To test how ambient temperature, heat index, and wet bulb globe temperature (WBGT) relate to hydration status and thermal heat perception in a hot, semi-arid environment.Subjects and methods: Urine samples, perceived heat stress, and anthropometrics were collected among Daasanach semi-nomadic pastoralists (n = 187 children, n = 231 adults) in northern Kenya. Environmental heat stress measures were recorded at sample collection; samples' urine specific gravity (USG) was measured.Results: Multiple linear and logistic regressions indicate that all environmental heat stress measures were associated with USG, odds of dehydration, and heat perception. Ambient temperature performed marginally better than WBGT, and both performed better than heat index. These associations were stronger among children than adults.Conclusion: In a hot, semi-arid climate, ambient temperature and WBGT accurately predict human water needs and heat stress, with children more vulnerable to dehydration. To mitigate consequences of extreme heat, local bioculturally-appropriate hydration (e.g. tea) and cooling (e.g. shade) strategies should be encouraged.","PeriodicalId":50765,"journal":{"name":"Annals of Human Biology","volume":"52 1","pages":"2456152"},"PeriodicalIF":1.8,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869389/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0