{"title":"A Mini Review on the Effects of Experimental Design, Including Variations in Participant Baseline Performance, When Testing the Efficacy of Polyphenol Consumption to Enhance Mood and Cognitive Function in Humans from a New Researcher Perspective","authors":"Duaa Altuwairki, Kirsten Brandt","doi":"10.3390/proceedings2023091344","DOIUrl":"https://doi.org/10.3390/proceedings2023091344","url":null,"abstract":"","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"255 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140448538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Evaluation of the Possibility of Using Buckwheat Hulls as an Addition to Bread","authors":"J. Klepacka, Marta Czarnowska-Kujawska","doi":"10.3390/proceedings2023091347","DOIUrl":"https://doi.org/10.3390/proceedings2023091347","url":null,"abstract":"","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"4 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139958246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sofia Tsitsou, E. Cholongitas, Triada Bali, Antonia Neonaki, K. Poulia, E. Papakonstantinou
{"title":"Effects of Time-Restricted Hypocaloric Mediterranean Diet in Patients with Non-Alcoholic Fatty Liver Disease: Preliminary Data from the CHRONO-NAFLD Project","authors":"Sofia Tsitsou, E. Cholongitas, Triada Bali, Antonia Neonaki, K. Poulia, E. Papakonstantinou","doi":"10.3390/proceedings2023091359","DOIUrl":"https://doi.org/10.3390/proceedings2023091359","url":null,"abstract":"","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"12 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139958265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xin Liu, Junqi Li, Jiawen Xie, Guoqing Ma, Kun Xu, Jiaomei Yang
{"title":"The Association between Body Fluid Rate with Plasma Lipid Profile, Independent of Adiposity in Young Adults","authors":"Xin Liu, Junqi Li, Jiawen Xie, Guoqing Ma, Kun Xu, Jiaomei Yang","doi":"10.3390/proceedings2023091355","DOIUrl":"https://doi.org/10.3390/proceedings2023091355","url":null,"abstract":"","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"37 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140449275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Grace O’Donovan, Daniel Allen, Thandile Nkosi-Gondwe, Kenneth Anujuo, Mubarek Abera, Amir Kirolos, C. Opondo, L. Olga, Debbie Thompson, A. Koulman, N. Lelijveld, Amelia C. Crampin, Marko Kerac, Change Study Collaborators Group CHANGE Study Collaborators Group
{"title":"Weight Gain among Children with Severe Malnutrition in Therapeutic Feeding Programmes: A Systematic Review and Meta-Analysis","authors":"Grace O’Donovan, Daniel Allen, Thandile Nkosi-Gondwe, Kenneth Anujuo, Mubarek Abera, Amir Kirolos, C. Opondo, L. Olga, Debbie Thompson, A. Koulman, N. Lelijveld, Amelia C. Crampin, Marko Kerac, Change Study Collaborators Group CHANGE Study Collaborators Group","doi":"10.3390/proceedings2023091338","DOIUrl":"https://doi.org/10.3390/proceedings2023091338","url":null,"abstract":": Background: Although 45 million children under five are wasted, the optimal rate of weight gain during treatment for severe malnutrition is unknown. Historically, inpatient treatment programmes focused on rapid weight gain (WG), with the rationale that this would optimise outcomes. However, recent evidence suggests that too rapid WG might be associated with higher cardiometabolic risk. Our objectives are as follows: describe WG in different programme types (e.g., inpatient, outpatient); explore any association between WG, average length of stay, and mortality/recovery; describe heterogeneity in WG reporting. Methods: For this systematic review and meta-analysis, we searched three databases: Embase (1947–2023), Global Health (1910–2023), and Medline (1946–2023), running the final search on 2nd May 2023. Papers were included if they re-ported average WG of children aged 6–59 months with severe malnutrition undergoing treatment. Non-English language and grey literature were excluded, except Emergency Nutrition Network Field Exchange articles. Summary data were extracted, and quality appraisal was done using a NICE Quality Appraisal Checklist. We conducted meta-analysis to describe pooled mean WG by programme type. We conducted meta-regression to investigate potential associations of WG with length of stay and programme outcomes. This study is registered with PROSPERO (CRD42023266472). Results: Our search yielded 3001 papers. We reviewed 307 full texts, identifying 127 eligible papers. Of these, 105 papers, with over 240,000 participants in total, reported WG as grams per kilogram per unit time and were eligible for meta-analysis. Mean rate of WG was 9.1 g/kg/d (95%CI 7.9, 10.3) across 19 inpatient programmes, and 3.9 g/kg/d (95%CI 3.5, 4.3) across 58 outpatient programmes. Faster WG was associated with shorter length of stay ( p < 0.001), but this was moderated by programme type. There was no association between WG and mortality/recovery in unadjusted analyses. There was high heterogeneity between studies. Lastly, 17% of papers did not report WG as grams per kilogram per unit time. Conclusions: Slower WG can be expected in outpatient programmes, compared to","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"32 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Vičič, Petra Pavlič, Valentina Rok, Saša Kugler, Andreja Kukec, Ruža Pandel Mikuš
{"title":"Assessment of Vitamin D Intake and Status in Slovenian Premenopausal and Postmenopausal Women","authors":"V. Vičič, Petra Pavlič, Valentina Rok, Saša Kugler, Andreja Kukec, Ruža Pandel Mikuš","doi":"10.3390/proceedings2023091333","DOIUrl":"https://doi.org/10.3390/proceedings2023091333","url":null,"abstract":"Presented","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140451655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cécile Gladine, N. Schebb, M. Touvier, A. Astrup, Philip Calder, A. Szuba, John W Newman
{"title":"Potential of Plasma Oxylipin Signature to Better Understand the Relationships between Diet, Fatty Acids and Oxylipins in Healthy Individuals: New Insights from Two Independent Cohort Studies","authors":"Cécile Gladine, N. Schebb, M. Touvier, A. Astrup, Philip Calder, A. Szuba, John W Newman","doi":"10.3390/proceedings2023091335","DOIUrl":"https://doi.org/10.3390/proceedings2023091335","url":null,"abstract":". Abstract: Eicosanoids and other oxylipins represent a superfamily of bioactive lipids involved in the regulation of crucial biological processes such as inflammation, blood clotting or endothelial reactivity. Oxylipins are generated from polyunsaturated fatty acids (PUFAs) through various enzymatic and free-radical-mediated reactions. Interestingly, each metabolic step (PUFA availability, enzyme activity and oxidative stress) can be influenced by diet. Oxylipins could therefore be important mediators of the effects of diet on human health. To provide new insights into the relationships between oxylipins, fatty acids (FAs) and diet, we conducted two independent cohort studies nested in the Polish branch of the PURE international cohort and in the French Nutrinet-Sant é cohort, respectively. The selected participants (n = 318) were healthy and fully characterized for their dietary intake. Our first objective was to determine if a healthy diet was associated with a specific oxylipin signature. Our secondary objective was to comprehensively investigate the relationships between diet, FAs and oxylipins. Participants were distributed into two groups according to the quality of their diet (based on the Alternative Healthy Eating Index (AHEI)). Targeted lipidomics was performed to comprehensively quantify plasma oxylipins and FAs. The association between oxylipins, FAs and the quality of the diet was modeled using conditional logistic regression. The relationships between oxylipins, FAs and diet were investigated using an unsupervised multiblock analysis (Multiblock Factorial Analysis (MFA)). We generated a unique database revealing unsuspected associations between diet, FAs and oxylipins. Validation studies are now required to further explore the potential of oxylipins to monitor the health effects of diet.","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"41 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140452128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. G. Duarte, Tushar More, C. M. Donado-Pestana, Rosa Maria Cerdeira Barros, Elias da Silva Araújo, Karsten Hiller, J. Fiamoncini
{"title":"Markers of Dysmetabolism Revealed Using a Dietary Challenge and Dry Blood Spots in a Remotely Executed Clinical Trial","authors":"S. G. Duarte, Tushar More, C. M. Donado-Pestana, Rosa Maria Cerdeira Barros, Elias da Silva Araújo, Karsten Hiller, J. Fiamoncini","doi":"10.3390/proceedings2023091339","DOIUrl":"https://doi.org/10.3390/proceedings2023091339","url":null,"abstract":"","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"18 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139958389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dietary Habits as Acne Trigger","authors":"Esma Karahmet Farhat, Ines Banjari, Tamara Jovović Sadiković","doi":"10.3390/proceedings2023091340","DOIUrl":"https://doi.org/10.3390/proceedings2023091340","url":null,"abstract":": Acne is the most common skin disease in the world and reason to visit a dermatologist. It affects more than 95% of adolescents, 3% of men and 12% of adult women. Exposure to stress, fast lifestyles, hormonal imbalances, gut dysbiosis, associated diseases, and eating habits can significantly contribute to the worsening of acne. The modern concept of acne treatment is holistic","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"141 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140451688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Harry Stevens, Francesco Piluso, Paolo Gasparini, Y. Mavrommatis, L. Pilic, C. Graham, M. P. Concas
{"title":"The Genetics of Sweet Taste: Perception, Feeding Behaviours, and Health","authors":"Harry Stevens, Francesco Piluso, Paolo Gasparini, Y. Mavrommatis, L. Pilic, C. Graham, M. P. Concas","doi":"10.3390/proceedings2023091342","DOIUrl":"https://doi.org/10.3390/proceedings2023091342","url":null,"abstract":": Background: Sweet taste is partly modified by genetics. The rs35874116 single-nucleotide polymorphism (SNP) in taste receptor type 1 member 2 (TAS1R2) reduces the availability of a G protein-coupled receptor (GPCR), which binds to ‘sweet’ molecules. This might alter sweet taste perception, diet choices, and health outcomes. However, these findings, and other genes and pathways involved in sweet taste are yet to be identified. Therefore, a candidate gene study on TAS1R2 and a genome-wide association study (GWAS) exploring these outcomes were performed. Methods: TAS1R2 rs35874116, sweet perception, liking, diet, and health were investigated in two age-and sex-matched European cohorts (UK, n = 50/Italy, n = 235). Linear models were used to explore associations. The GWAS was performed with 2555 Italian participants. Associations with sweet food liking, food adventurousness (FA), reward dependence (RD), and health were explored. Results: The wildtype of TAS1R2 was associated with increased sweet taste and food liking ( p = 0.049, β = 0.62, p = 0.038, β = 0.45), increased fibre consumption ( p = 0.006, β = 7.95), and decreased HDL cholesterol ( p = 0.025, β = − 3.56). The GWAS identified rs58931966 in the regulator of G-protein signalling 9 (RGS9) gene. The minor allele was associated with decreased sweet food liking ( p = 7.05 × 10 – 9, β = 0.3), a higher BMI ( p = 0.007, β = 0.391), serum glucose ( p = 0.013, β = 1.211), lower FA ( p = 0.049, β = − 0.065), and RD ( p = 0.011, β = − 3.840). Discussion: The TAS1R2 results show that taste receptor variations are associated with preference, diet, and health-related outcomes. TAS1R2 not reaching significance in the GWAS shows that sweet food liking is modified by pathways besides taste reception. RSG9 is expressed in the striatum, which is involved in the mesolimbic reward pathway, which is activated by sweet taste. RGS9 rs58931966 may moderate dopaminergic signalling in response to sweet foods via the negative regulation of G-protein signalling. This might explain why the minor allele was associated with reduced RD. The lower FA might decrease preference for bitter-tasting vegetables, which could explain the higher BMI and serum glucose. The FA and RD results provide evidence that food choice depends on psychological/biological interplay. These results show that sweet taste is modified by multiple pathways and genes, and variations can modify taste, diet, and health outcomes.","PeriodicalId":507355,"journal":{"name":"The 14th European Nutrition Conference FENS 2023","volume":"25 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}