Behavioural Neurology最新文献_第8页

Sex Modified the Association between Sleep Duration and worse Cognitive Performance in Chinese Hypertensive Population: Insight from the China H-Type Hypertension Registry Study. 性别改变了中国高血压人群睡眠时间与认知能力差之间的关系:来自中国h型高血压登记研究的见解

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-06-24 eCollection Date: 2022-01-01 DOI: 10.1155/2022/7566033

Xinlei Zhou, Junpei Li, Chao Yu, Wangsheng Fang, Yanyou Xie, Li Wang, Si Shen, Wei Zhou, Lingjuan Zhu, Tao Wang, Xiao Huang, Huihui Bao, Jianglong Tu, Xiaoshu Cheng

{"title":"Sex Modified the Association between Sleep Duration and worse Cognitive Performance in Chinese Hypertensive Population: Insight from the China H-Type Hypertension Registry Study.","authors":"Xinlei Zhou, Junpei Li, Chao Yu, Wangsheng Fang, Yanyou Xie, Li Wang, Si Shen, Wei Zhou, Lingjuan Zhu, Tao Wang, Xiao Huang, Huihui Bao, Jianglong Tu, Xiaoshu Cheng","doi":"10.1155/2022/7566033","DOIUrl":"https://doi.org/10.1155/2022/7566033","url":null,"abstract":"Objectives: Cognitive decline could be seen as the sign of preclinical phase of dementia, which was found to be sex differentiated. Previous studies had discovered that there might be some link between abnormal sleep duration and cognitive performance. Additionally, hypertension was found to be one of the important risk factors for cognitive decline and abnormal sleep duration was also a significant risk factor for hypertension. Therefore, the purpose of this study was to investigate sex differences in the association of sleep duration with cognitive performance and to further explore potential effect modifiers that may exist.Methods: Data analyzed in this study was from the China H-type Hypertension Registry Study. Sleep duration was assessed with a sleep questionnaire and categorized as <5 hours, 5-8 hours, and ≥8 hours. Cognitive performance was evaluated with the Mini-Mental State Examination (MMSE).Result: A total of 9527 subjects were included. The average age was 63.7 ± 9.8 years. Linear regression analyses showed that the association between long sleep duration (≥8 h) and MMSE score adjusting for pertinent covariables was stronger in female (β = -0.95, 95% CI: -1.23 to -0.68, P < 0.001) than in male (β = -0.29, 95% CI: -0.53 to -0.06, P = 0.013). Furthermore, there was a significant interaction between sleep duration and age on cognitive performance only in female.Conclusion: In summary, this study found that long sleep duration (≥8 h) was associated with poorer cognitive performance. Furthermore, this association was more pronounced in female than in male, especially in older female.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40468370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exercise Improves Spatial Learning and Memory Performance through the Central GLP-1 Receptors. 运动通过中枢GLP-1受体改善空间学习和记忆表现。

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-06-21 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2900628

Majid Taati, Peyman Esmaeili Fard Barzegar, Abbas Raisi

{"title":"Exercise Improves Spatial Learning and Memory Performance through the Central GLP-1 Receptors.","authors":"Majid Taati, Peyman Esmaeili Fard Barzegar, Abbas Raisi","doi":"10.1155/2022/2900628","DOIUrl":"https://doi.org/10.1155/2022/2900628","url":null,"abstract":"The glucagon-like peptide 1 (GLP-1) is a hormone which is produced in the enteroendocrine L-cells in the ileum and the neurons of nucleus tractus solitarius (NTS) in the brain which has numerous metabolic effects. The central GLP-1R's role in cognitive functioning is well known. On the contrary, it has been shown that exercise has positive effects on brain function. So, we decided to elucidate whether the central GLP-1 has a role in memory and learning. Thirty-two rats were used in this experiment in 4 groups. After anesthetizing the rats, the right lateral ventricle was detected, and a cannula was directed to the ventricle. Ten micrograms of exendin-3 or sterile saline, according to the group, was injected via ICV once daily for seven days. The rats in the exercise group considered an exercise period of one hour each day (17 meters per minute) for seven consecutive days. To evaluate the performance of memory and learning, a standard Morris water maze (MWM) tank was utilized. According to the results, the TE-exendin group showed a statistically significant difference from the TE-SAL group in both parameters of latency and time in the zone. In summary, memory and learning were improved by GLP-1R in the exercise group, but not in the sedentary group, which we can hypothesize that exercise can affect memory and learning through this pathway.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9239811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40550759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Association between Physical Activity and Cognitive Function: Data from the China Health and Nutrition Survey. 体育活动与认知功能的关系:来自中国健康与营养调查的数据。

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-06-20 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3438078

Qiankun Huang, Jing Zhao, Weiqing Jiang, Wenfeng Wang

{"title":"The Association between Physical Activity and Cognitive Function: Data from the China Health and Nutrition Survey.","authors":"Qiankun Huang, Jing Zhao, Weiqing Jiang, Wenfeng Wang","doi":"10.1155/2022/3438078","DOIUrl":"https://doi.org/10.1155/2022/3438078","url":null,"abstract":"Background: Decreased cognitive function is a common problem in the old adults, which has high risk of progression to Alzheimer's diseases (AD) and other dementias. This study was aimed at finding out the association between physical activity and cognitive function.Methods: In total, 1514 participants with the age ≥ 55 years old registered in the China Health and Nutrition Survey (CHNS) database were selected in this study. The association between physical activity and cognitive function was analyzed via the generalized additive model. The association between the variables and the cognitive function score was expressed as β coefficient with 95% confidence intervals (CIs).Results: After adjusting age, ethnicity, stratum, marital status, education, memory status, and memory changes, the cognitive function score was increased by 0.011 points for every 1-point increase in domestic score (β = 0.011, P = 0.043). Subgroup analysis indicated that in the female group, for every 1-point increase in the domestic score, the cognitive function score increased by 0.019 points (β = 0.019, P = 0.017). In people with good memory status, each 1-point increase in domestic score increased the cognitive function score of 0.020 points (β = 0.020, P = 0.017).Conclusions: The decreased cognitive function was correlated with decreased domestic physical activity. The increased domestic physical activity was associated with an increased cognitive function in females and people with good memory status. The findings might offer a reference for deep understanding of the association between physical activity and cognitive function.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9236826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40409696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Prophylactic Zinc Administration Combined with Swimming Exercise Prevents Cognitive-Emotional Disturbances and Tissue Injury following a Transient Hypoxic-Ischemic Insult in the Rat 锌的预防性给药与游泳运动相结合预防大鼠短暂性缺氧缺血性损伤后的认知情绪障碍和组织损伤

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-05-20 DOI: 10.1155/2022/5388944

A. Aguilar-Peralta, Alejandro González-Vázquez, Constantino Tomás-Sanchez, Victor M Blanco-Alvarez, D. Martínez-Fong, J. González-Barrios, I. D. Limón, Lourdes Millán-Pérez Peña, G. Flores, Guadalupe Soto-Rodriguez, E. Brambila, J. Cebada, Viridiana Vargas-Castro, B. A. Leon-Chavez

{"title":"Prophylactic Zinc Administration Combined with Swimming Exercise Prevents Cognitive-Emotional Disturbances and Tissue Injury following a Transient Hypoxic-Ischemic Insult in the Rat","authors":"A. Aguilar-Peralta, Alejandro González-Vázquez, Constantino Tomás-Sanchez, Victor M Blanco-Alvarez, D. Martínez-Fong, J. González-Barrios, I. D. Limón, Lourdes Millán-Pérez Peña, G. Flores, Guadalupe Soto-Rodriguez, E. Brambila, J. Cebada, Viridiana Vargas-Castro, B. A. Leon-Chavez","doi":"10.1155/2022/5388944","DOIUrl":"https://doi.org/10.1155/2022/5388944","url":null,"abstract":"Exercise performance and zinc administration individually yield a protective effect on various neurodegenerative models, including ischemic brain injury. Therefore, this work was aimed at evaluating the combined effect of subacute prophylactic zinc administration and swimming exercise in a transient cerebral ischemia model. The prophylactic zinc administration (2.5 mg/kg of body weight) was provided every 24 h for four days before a 30 min common carotid artery occlusion (CCAO), and 24 h after reperfusion, the rats were subjected to swimming exercise in the Morris Water Maze (MWM). Learning was evaluated daily for five days, and memory on day 12 postreperfusion; anxiety or depression-like behavior was measured by the elevated plus maze and the motor activity by open-field test. Nitrites, lipid peroxidation, and the activity of superoxide dismutase (SOD) and catalase (CAT) were assessed in the temporoparietal cortex and hippocampus. The three nitric oxide (NO) synthase isoforms, chemokines, and their receptor levels were measured by ELISA. Nissl staining evaluated hippocampus cytoarchitecture and Iba-1 immunohistochemistry activated the microglia. Swimming exercise alone could not prevent ischemic damage but, combined with prophylactic zinc administration, reversed the cognitive deficit, decreased NOS and chemokine levels, prevented tissue damage, and increased Iba-1 (+) cell number. These results suggest that the subacute prophylactic zinc administration combined with swimming exercise, but not the individual treatment, prevents the ischemic damage on day 12 postreperfusion in the transient ischemia model.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46280662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of the NMDA Receptor in the Anticonvulsant Effect of Ellagic Acid in Pentylenetetrazole-Induced Seizures in Male Mice NMDA受体在Ellagic酸对戊四唑诱导的雄性小鼠癫痫发作的抗惊厥作用中的作用

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-05-11 DOI: 10.1155/2022/9015842

Mohammad Rahimi-Madiseh, Z. Lorigooini, Shakiba Nasiri Boroujeni, Marziyeh Taji, H. Amini-khoei

引用次数: 2

Neuropsychiatric Symptoms in Clinically Defined Parkinson's Disease: An Updated Review of Literature 临床定义帕金森病的神经精神症状:最新文献综述

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-05-09 DOI: 10.1155/2022/1213393

Paloma Macías-García, Raúl Rashid-López, Á. J. Cruz-Gómez, Elena Lozano-Soto, Florencia Sanmartino, R. Espinosa-Rosso, J. González-Rosa

{"title":"Neuropsychiatric Symptoms in Clinically Defined Parkinson's Disease: An Updated Review of Literature","authors":"Paloma Macías-García, Raúl Rashid-López, Á. J. Cruz-Gómez, Elena Lozano-Soto, Florencia Sanmartino, R. Espinosa-Rosso, J. González-Rosa","doi":"10.1155/2022/1213393","DOIUrl":"https://doi.org/10.1155/2022/1213393","url":null,"abstract":"Background Neuropsychiatric symptoms (NPS) are a common and potentially serious manifestation of Parkinson's disease (PD) but are frequently overlooked in favor of a focus on motor symptomatology. Here, we conducted a literature review of the prevalence and type of NPS experienced by PD patients with a clinically defined course of their illness. Methods We identified reports of NPS in patients with PD and mean disease duration over 3 years. Three databases—PubMed, Scopus, and Dialnet—were searched for relevant literature published between 2010 and 2020. Predefined exclusion criteria were applied prior to a descriptive analysis of the literature base. Results In all, 87 unique reports were identified and 30 met inclusion and exclusion criteria. These included 7142 patients with PD (male: 67.3%; mean age: 66.2 years; mean disease duration: 6.7 years). The most frequent NPS were mood disorders (apathy, depression, and anxiety), psychosis, and impulse control disorders (ICD). Treatment with dopamine agonists was identified as an important risk factor for ICD. Co-occurrence of NPS and cognitive dysfunction was also evidenced in a number of studies. Patients with more significant cognitive deficits and higher levels of NPS appeared to be of older age with a longer disease duration and to have more severe motor symptoms. Conclusions NPS, most commonly mood disorders (apathy, depression, and anxiety), psychosis, and ICDs are frequent manifestations of PD. The results of this review reflect the need to develop unified validated assessment protocols for NPS in PD, as well as to improve their management in clinical practice.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45302098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Shared Etiology in Autism Spectrum Disorder and Epilepsy with Functional Disability 自闭症谱系障碍和癫痫伴功能障碍的共同病因

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-04-27 DOI: 10.1155/2022/5893519

Aqeela Zahra, YunFu Wang, Qun Wang, Jianping Wu

引用次数: 6

The Mental Status Examination Handbook. 精神状态检查手册。

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-04-27 DOI: 10.1097/WNN.0000000000000306

H. Kirshner

引用次数: 3

Protective Effect of Melatonin on Nonylphenol-Induced Reproductive and Behavioral Disorders in First-Generation Adult Male Rats 褪黑素对壬基酚诱导的第一代成年雄性大鼠生殖和行为障碍的保护作用

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-04-26 DOI: 10.1155/2022/1877761

Mahsa Tavakoli, A. Moghadamnia, F. Pourabdolhossein, M. Asghari, S. Kazemi

{"title":"Protective Effect of Melatonin on Nonylphenol-Induced Reproductive and Behavioral Disorders in First-Generation Adult Male Rats","authors":"Mahsa Tavakoli, A. Moghadamnia, F. Pourabdolhossein, M. Asghari, S. Kazemi","doi":"10.1155/2022/1877761","DOIUrl":"https://doi.org/10.1155/2022/1877761","url":null,"abstract":"Methods Pregnant Wistar rats were randomly assigned into five groups: control, NP (25 mg/kg), NP (25 mg/kg)+MLT (10 mg/kg), NP (25 mg/kg)+MLT (20 mg/kg), and MLT (20 mg/kg). The duration of treatment was 21 days from gestation time. Morris water maze was used to assess learning and memory. NP concentrations of serum and testicular tissue were measured by HPLC. Histological analysis of testicular tissues was done by H&E staining. Results Behavioral study showed that NP does not impair learning and memory in first-generation rats. Histomorphometric results showed that NP can significantly reduce the cross-sectional area of the seminiferous tubules and the epithelium, the diameter and number of seminiferous tubules, the thickness of the epithelium, and the number of spermatocytes and spermatogonia compared to other groups. MLT reversed the NP-induced histomorphometric. Also, it changes and increased the activity of superoxide dismutase (SOD), total antioxidant capacity (TAC), and catalase (CAT). The level of malondialdehyde (MDA) significantly decreased in MLT-treated groups compared with the NP group. Conclusion Our finding showed that MLT enhanced the learning process and reduced NP-induced testicular tissue damage through its antioxidants and cytoprotective effects.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42951634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Graph Theoretical Analysis of Semantic Fluency in Patients with Parkinson's Disease 帕金森病患者语义流畅性的图论分析

IF 2.8 4区医学

Behavioural Neurology Pub Date : 2022-04-23 DOI: 10.1155/2022/6935263

Guanyu Zhang, Jinghong Ma, P. Chan, Zheng Ye

{"title":"Graph Theoretical Analysis of Semantic Fluency in Patients with Parkinson's Disease","authors":"Guanyu Zhang, Jinghong Ma, P. Chan, Zheng Ye","doi":"10.1155/2022/6935263","DOIUrl":"https://doi.org/10.1155/2022/6935263","url":null,"abstract":"Semantic fluency is the ability to name items from a given category within a limited time, which relies on semantic memory, working memory, and executive function. Semantic disfluency is a common problem in Parkinson's disease (PD) and Alzheimer's disease (AD). We demonstrated a graph theoretical analysis of semantic fluency in patients with PD (N = 86), patients with AD (N = 40), and healthy controls (HC, N = 88). All participants completed a standard animal fluency test. Their verbal responses were recorded, transcripted, and transformed into directed speech graphs. Patients with PD generated fewer correct words than HC and more correct words than patients with AD. Patients with PD showed higher density, shorter diameter, and shorter average shortest path length than HC, but lower density, longer diameter, and longer average shortest path length than patients with AD. It suggests that patients with PD produced relatively smaller and denser speech graphs. Moreover, in PD, the densities of speech graphs correlated with the severity of non-motor symptoms, but not the severity of motor symptoms. The graph theoretical analysis revealed new features of semantic disfluency in patients with PD.","PeriodicalId":50733,"journal":{"name":"Behavioural Neurology","volume":null,"pages":null},"PeriodicalIF":2.8,"publicationDate":"2022-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45011986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2