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The association between neighborhood disadvantage and patient-reported outcomes in burn survivors 烧伤幸存者的邻里劣势与患者报告结果之间的关系
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.06.013
Arushi Biswas , Zachary H. Zamore , Zohra Aslami , Rafael Felix P. Tiongco , Ayman Ali , Carisa M. Cooney , Mark D. Fisher , Julie A. Caffrey , Sheera F. Lerman
{"title":"The association between neighborhood disadvantage and patient-reported outcomes in burn survivors","authors":"Arushi Biswas ,&nbsp;Zachary H. Zamore ,&nbsp;Zohra Aslami ,&nbsp;Rafael Felix P. Tiongco ,&nbsp;Ayman Ali ,&nbsp;Carisa M. Cooney ,&nbsp;Mark D. Fisher ,&nbsp;Julie A. Caffrey ,&nbsp;Sheera F. Lerman","doi":"10.1016/j.burns.2024.06.013","DOIUrl":"10.1016/j.burns.2024.06.013","url":null,"abstract":"<div><h3>Background</h3><div>Burns can cause long-term complications including pain and poor physical function. While neighborhood disadvantage is associated with burn severity, its effect on long-term complications has not been investigated. We hypothesized that patients from areas of higher area of deprivation index (ADI) will report poorer long-term outcomes.</div></div><div><h3>Methods</h3><div>We linked patient data from the Burn Model System with ADI state decile (1 = least, 10 = most disadvantaged) using year and residence at time of injury. We performed bivariate analyses to identify associations between ADI and patient and burn characteristics and multivariate regressions to determine whether ADI was associated with PROMIS-29 pain and physical function 6- and 24-months post-burn.</div></div><div><h3>Results</h3><div>We included 780 patients; 69 % male, median age = 46 years, median ADI = 6, and median TBSA = 8 %. Multivariate regressions adjusting for TBSA, race, age, sex, anxiety, depression, and pain interference demonstrated that higher ADI was a significant predictor of higher pain intensity 6- (p = 0.001) and 24-months (p = 0.037) post-burn but not worse physical function 24-months post-burn (p = 0.089).</div></div><div><h3>Conclusions</h3><div>Higher neighborhood disadvantage was associated with higher long-term pain intensity post-burn. This study highlights the importance of socioeconomic factors that may impact long-term outcomes and the use of aggregate markers to identify patients at risk for worse outcomes.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107196"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141577607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome comparison of the most commonly employed wound coverage techniques in patients with massive burns ≥50% TBSA – A systematic review and meta-analysis 大面积烧伤(TBSA ≥50%)患者最常采用的伤口覆盖技术的效果比较 - 系统综述与荟萃分析
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.07.014
Valentin Haug , Christian Tapking , Adriana C. Panayi , Anamika Veeramani , Samuel Knoedler , Bianief Tchiloemba , Obada Abdulrazzak , Nikita Kadakia , Bastian Bonaventura , Derek Culnan , Ulrich Kneser , Gabriel Hundeshagen
{"title":"Outcome comparison of the most commonly employed wound coverage techniques in patients with massive burns ≥50% TBSA – A systematic review and meta-analysis","authors":"Valentin Haug ,&nbsp;Christian Tapking ,&nbsp;Adriana C. Panayi ,&nbsp;Anamika Veeramani ,&nbsp;Samuel Knoedler ,&nbsp;Bianief Tchiloemba ,&nbsp;Obada Abdulrazzak ,&nbsp;Nikita Kadakia ,&nbsp;Bastian Bonaventura ,&nbsp;Derek Culnan ,&nbsp;Ulrich Kneser ,&nbsp;Gabriel Hundeshagen","doi":"10.1016/j.burns.2024.07.014","DOIUrl":"10.1016/j.burns.2024.07.014","url":null,"abstract":"<div><h3>Introduction</h3><div>Early wound coverage is one of the most essential factors influencing the survival of extensively burned patients, especially those with a total body surface area (TBSA) burned greater than 50 %. In patients with limited donor sites available for autografting, techniques such as the Meek micrograft procedure or cultured epidermal allografts (CEA) have proven to be viable alternatives. In this systematic review and meta-analysis, we analyzed the outcomes of different wound coverage techniques in patients with massive burn injuries ≥ 50 % TBSA in the past 17 years.</div></div><div><h3>Methods</h3><div>The EMBASE, PUBMED, Google Scholar and MEDLINE databases were searched from inception to December 2022 for studies investigating major burn reconstruction (&gt;50 % TBSA) with the use of one of: a) autografts, b) allografts, c) cell-based therapies, and d) Meek micrografting. The review was conducted in accordance with the PRISMA guidelines. The outcomes evaluated were mortality, length of hospital stay, graft take and number of operations performed.</div></div><div><h3>Results</h3><div>Following a two-stage review process, 30 studies with 1369 patients were identified for analysis. Methods of coverage comprised the original autografting, and the newer Meek micrografting, CEA autografting, and allografting. Pooled mean age of the entire cohort was 32.5 years ( ± SE 3.6) with mean burn size of 66.1 % ( ± 2.5). After pooling the data, advantages in terms of mortality rate, length of stay, graft take and number of required surgeries were seen for the Meek and CEA groups. Mortality was highest in patients treated with autografts (50 %) and lowest with cell-based therapy (11 %). Length of stay was longest with cell-based therapy (91 ± 16 days) and shortest with Meek micrografting (50 ± 24 days). Graft take was highest with autografts (96 ± 2 %) and lowest with cell-based therapy (72 ± 9 %). Average number of operations was highest with cell-based therapy (9 ± 4) and lowest with Meek micrografting (4 ± 2).</div></div><div><h3>Conclusions</h3><div>Comparison of the four techniques highlighted differences in terms of all outcomes assessed, and each technique was associated with different advantages. Interestingly autografting, the option with the highest graft take rate, was also associated with the highest mortality. This study not only serves to provide the first comparison of the most commonly used techniques in major burn reconstruction, but also highlights the need for prospective studies that directly compare the efficacy of the different techniques to ultimately establish whether a true superior option exists.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107210"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141839604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
National Academy of Burns India (NABI) online tutorials: Pursuit of excellence in burns education 印度国家烧伤学院 (NABI) 在线教程:追求卓越的烧伤教育
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.07.027
Veena Kumari Singh , Sanjeev Uppal , Raj Manas , Sameek Bhattacharya
{"title":"National Academy of Burns India (NABI) online tutorials: Pursuit of excellence in burns education","authors":"Veena Kumari Singh ,&nbsp;Sanjeev Uppal ,&nbsp;Raj Manas ,&nbsp;Sameek Bhattacharya","doi":"10.1016/j.burns.2024.07.027","DOIUrl":"10.1016/j.burns.2024.07.027","url":null,"abstract":"<div><h3>Introduction</h3><div>The COVID-19 pandemic led to a sudden halt in the academic activities of many medical professionals including burns and plastic surgery. Worldwide, this led to many societies switching over to various virtual platforms like Google Meet and Zoom for teaching and training. In India, as the other plastic surgery societies started their educational webinars, the National Academy of Burns India (NABI) also geared up for its web journey for imparting burn education to doctors and the general population.</div></div><div><h3>Methodology</h3><div>Webinars were conducted in four series – acute burn care, post-burn reconstructions, video demonstrations of burn procedures, and research in burns. The first series included a specialist from an allied department. To reach the public and non-medical population, the burn tutorials for general awareness were live-streamed on social media, and the teaching was done in the form of a panel discussion between the speakers and moderators.</div></div><div><h3>Results</h3><div>A total of 54 webinars including 29 for professionals and 25 for the public were conducted between October 2020 to December 2023 in four series. The participation of professionals on the virtual platform was comparable to a burns conference and an extremely encouraging response was received to the NABI tutorials conducted on social media for the public.</div></div><div><h3>Conclusion</h3><div>NABI webinars showed that education in burns is possible on a virtual platform under special circumstances like the COVID-19 pandemic and can be used as an adjunct to regular teaching and training. The public awareness webinars also served as readily available resource material for the general population.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107223"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141846957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dental health concerns for patients suffering from facial, peri-oral burns, and inhalation injury: A persistent yet underappreciated challenge 面部、口周烧伤和吸入性损伤患者的牙科健康问题:一个长期存在但未被重视的挑战
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.07.028
Hans-Oliver Rennekampff , Isabelle Rennekampff , Mayer Tenenhaus
{"title":"Dental health concerns for patients suffering from facial, peri-oral burns, and inhalation injury: A persistent yet underappreciated challenge","authors":"Hans-Oliver Rennekampff ,&nbsp;Isabelle Rennekampff ,&nbsp;Mayer Tenenhaus","doi":"10.1016/j.burns.2024.07.028","DOIUrl":"10.1016/j.burns.2024.07.028","url":null,"abstract":"<div><div>Demographic data reveal a correlative relationship between facial burns and profoundly impaired dental health, while inhalation injury correlates with a high Periodontal Screening and Recording Index, both of which significantly reduce quality of life for the burn injury patient. Despite these facts, few if any burn centers surveyed in the U.S. or Germany enlist specialized services and well-defined follow-up protocols for patients who might well be at risk.</div><div>Facial burns represent a severe injury, the consequence of which may tragically lead to significant and long lasting functional, esthetic, and psychological sequelae such as perioral scarring, deformity and microstomia. Inhalation injury from inhaled heated air, gas, and chemical exposure are well-known causes of early as well as late airway injury, morbidity, and death. Thermal injury patterns to perioral-related and dental structures is increasingly being recognized.</div><div>This review delineates current burn-related dental health pathology and when available the underlying causation. These findings may help guide future research as well as therapeutic strategies to improve dental health and outcome for our patients.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107224"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhancing the evaluation of burn scar quality 加强烧伤疤痕质量评估。
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.08.009
Hojat Eftekhari
{"title":"Enhancing the evaluation of burn scar quality","authors":"Hojat Eftekhari","doi":"10.1016/j.burns.2024.08.009","DOIUrl":"10.1016/j.burns.2024.08.009","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107243"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized, controlled, within-patient, single-blinded pilot study to evaluate the efficacy of 12-weeks of endermotherapy with adult burn survivors 对成年烧伤幸存者进行为期 12 周的内皮疗法疗效评估的随机对照单盲试点研究。
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.09.008
Bernadette Nedelec , Zoë Edger-Lacoursière , Nathalie Gauthier , Elisabeth Marois-Pagé , Stéphanie Jean
{"title":"Randomized, controlled, within-patient, single-blinded pilot study to evaluate the efficacy of 12-weeks of endermotherapy with adult burn survivors","authors":"Bernadette Nedelec ,&nbsp;Zoë Edger-Lacoursière ,&nbsp;Nathalie Gauthier ,&nbsp;Elisabeth Marois-Pagé ,&nbsp;Stéphanie Jean","doi":"10.1016/j.burns.2024.09.008","DOIUrl":"10.1016/j.burns.2024.09.008","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Vacuum massage, or endermotherapy, is applied to scar tissue with the primary therapeutic goal of promoting structural or physiological changes. These changes are intended to enhance pliability, enabling the skin to possess the strength and elasticity required for normal mobility. The advantage of vacuum massage compared to therapist-generated manual massage is that it provides a standardized dosage using rollers and suction valves to mobilize the tissue. However, research documenting and supporting its impact on post-burn hypertrophic scar is lacking. Thus, this study was designed to objectively characterize the changes in scar elasticity, erythema, melanin, thickness, and transepidermal water loss immediately after a vacuum massage session and after a 12-week course of treatment compared to intra-individual matched control scars.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;We conducted a prospective, randomized, controlled, within-patient, single-blinded clinical trial, initially designed as a fully-powered study but limited to a pilot study due to COVID-19 restrictions. Nineteen burn survivors consented to participate and 16 completed the study. Two homogeneous, intra-individual scars were randomized to usual care control or vacuum massage therapy plus usual care. Vacuum massage interventions were provided by a certified massage therapist three times per week for 12 weeks. Scar characteristics were evaluated every four weeks immediately before and after mechanical massage treatment. The evaluations included measurements of elasticity (Cutometer), erythema and melanin (Mexameter), transepidermal water loss (TEWL) (Tewameter), and thickness (high-frequency ultrasound). Linear mixed-model analyses were performed to test for immediate and long-term treatment effects.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;The ANOVA analyses revealed a non-significant time:treatment interaction for elasticity, erythema, melanin, thickness, or TEWL. There was a significant increase in elasticity and erythema and a decrease in TEWL in both the control and treatment sites over time with consistent standard care. However, there was no statistically significant immediate or long-term treatment effect for any of the skin characteristics. Nonetheless, the mean participant satisfaction was 4/5 (SD = 1.5) and the mean participant perception of effectiveness was 8/10 (SD = 1.9).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;This pilot study did not find a treatment benefit of vacuum massage therapy for elasticity, erythema, melanin, thickness or TEWL, but it did find an improvement with time in elasticity, erythema and TEWL. Despite the lack of objective improvement of the treated scar site, participants were satisfied with the results and believed vacuum massage was very effective. Further high-quality research is required to better inform clinicians patient education and treatment decisions for this costly, burdensome treatment approach that has high partici","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107269"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The prognostic relevance of full-thickness burns on ABSI 全层烧伤对 ABSI 预后的影响
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.07.001
J. Gorenflo , B. Reichert , German Burn Registry , S. Reif , I.-F. Megas , M. Billner
{"title":"The prognostic relevance of full-thickness burns on ABSI","authors":"J. Gorenflo ,&nbsp;B. Reichert ,&nbsp;German Burn Registry ,&nbsp;S. Reif ,&nbsp;I.-F. Megas ,&nbsp;M. Billner","doi":"10.1016/j.burns.2024.07.001","DOIUrl":"10.1016/j.burns.2024.07.001","url":null,"abstract":"<div><h3>Introduction</h3><div>The Abbreviated Burn Severity Index (ABSI) by Tobiasen, which is commonly used to estimate the mortality risk of severely burned patients, calculates an additional point for the existence of full-thickness (third-degree) burns. [1] However, the score does not consider the extent of the body surface affected by third-degree burns. To understand whether there is a way to improve ABSI prediction power, this study aims to determine the influence of full-thickness burns on survival rates and how it affects the predictive precision of the ABSI.</div></div><div><h3>Material and methods</h3><div>In this study, the statistical evaluation of 2538 patients collected prospectively in the context of the German Burn Registry was carried out. A linear regression analysis was carried out to show the prognostic relevance of full-thickness burns. Age, sex, total body surface area burned (TBSA), and the presence of inhalation injury were also observed as further influencing factors.</div></div><div><h3>Results</h3><div>Among the 2538 patients meeting our inclusion criteria, full-thickness burns were found in 1233 patients. In patients with a TBSA below 20 %, the extent of full-thickness burns is not relevant to the prognosis in terms of survival probability (p = 0.124). With more than 20 % TBSA, the extent of third-degree burns is of significant relevance (p = 0.000). In patients without full-thickness burns and calculated ABSI values ≥ 12 the survival rate of 46 % was noticeably better than the predicted survival rate of &lt; 10 % according to the ABSI Score, whereas the predicted survival rate in patients with third-degree burns (&lt; 10 %), closely matched the observed survival rate of 11 %.</div></div><div><h3>Conclusion</h3><div>For patients with a TBSA &lt; 20 %, the presence of full-thickness burns is not relevant for survival. In contrast to this observation, the percentage of full-thickness burns is of crucial prognostic importance for patients with a TBSA of &gt; 20 %. By adjusting the ABSI and taking into account the exact percentage of third-degree burns, an improvement in the prognostic precision of the score could be achieved.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107197"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Scholarly knowledge fundamentals and dynamic research hotspots in the field of burns and immunology: A bibliometric analysis 烧伤和免疫学领域的学术知识基础和动态研究热点:文献计量分析
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.07.024
Luofeng Jiang , Yushu Zhu , Wei Zhang , Sujie Xie , Minjuan Wu , Dayuan Xu , Siqiao Wang , Shuyuan Xian , Jianyu Lu , Xirui Tong , Yifan Liu , Jie Huang , Xinya Guo , Minyi Gu , Shuxin Jin , Yicheng Ma , Runzhi Huang , Shizhao Ji , Zhaofan Xia
{"title":"Scholarly knowledge fundamentals and dynamic research hotspots in the field of burns and immunology: A bibliometric analysis","authors":"Luofeng Jiang ,&nbsp;Yushu Zhu ,&nbsp;Wei Zhang ,&nbsp;Sujie Xie ,&nbsp;Minjuan Wu ,&nbsp;Dayuan Xu ,&nbsp;Siqiao Wang ,&nbsp;Shuyuan Xian ,&nbsp;Jianyu Lu ,&nbsp;Xirui Tong ,&nbsp;Yifan Liu ,&nbsp;Jie Huang ,&nbsp;Xinya Guo ,&nbsp;Minyi Gu ,&nbsp;Shuxin Jin ,&nbsp;Yicheng Ma ,&nbsp;Runzhi Huang ,&nbsp;Shizhao Ji ,&nbsp;Zhaofan Xia","doi":"10.1016/j.burns.2024.07.024","DOIUrl":"10.1016/j.burns.2024.07.024","url":null,"abstract":"<div><h3>Background</h3><div>An estimated 180,000 burn deaths occur each year, and the immune system plays a vital role in wound healing and burn complications, including inflammatory reactions and oxidative stress. This paper aims to explore the basic knowledge and dynamic hotspots in burns and immunology research with bibliometric methods.</div></div><div><h3>Methods</h3><div>Through systematic retrieval, we ensured all the documents complied with our retrieval strategy and were included in the Science Citation Index-Expanded of the Web of Science Core Collection. Using bibliometric methodologies, the general information was delineated; and foundational knowledge, as well as dynamic research hotspots, were ascertained through VOSviewer, CiteSpace, and R-bibliometrix.</div></div><div><h3>Results</h3><div>8758 publications were identified from January 1st, 2000, to June 17th, 2024. The most productive and collaborative country was the USA; Harvard University was the most productive affiliation; and the most productive author was David N. Herndon. According to source analysis, the highest-impact journal is <em>Burns</em>. Historically, “expression” was the most frequently occurring word. “Delivery” was the most frequently occurring word in recent years.</div></div><div><h3>Conclusion</h3><div>The domain of burns and immunology has reached a zenith, with a modest decline in publication output over the past two years, yet it continues to evolve robustly. The focal points of inquiry have evolved from the initial appraisal of immunotherapeutic interventions for critical burn injuries to the elucidation of immune cell mechanisms in burn patients. Future research trajectory is poised to innovate therapeutic modalities, encompassing anti-inflammatory, antioxidant, and targeted drug delivery systems, to enhance precision in immune modulation.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107220"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Has the energy poverty crisis fuelled a rise in hot water bottle burn injuries within the United Kingdom? 能源贫困危机是否加剧了英国热水瓶烫伤事件的增加?
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.09.014
Mr. Howard Chu , Laveena Yarlagadda , Mr. Christopher Wearn
{"title":"Has the energy poverty crisis fuelled a rise in hot water bottle burn injuries within the United Kingdom?","authors":"Mr. Howard Chu ,&nbsp;Laveena Yarlagadda ,&nbsp;Mr. Christopher Wearn","doi":"10.1016/j.burns.2024.09.014","DOIUrl":"10.1016/j.burns.2024.09.014","url":null,"abstract":"<div><h3>Introduction</h3><div>There are an estimated 10 million hot water bottles (HWB) currently in use within the United Kingdom (UK), and HWB related burn injuries represent a significant resource burden to UK Burns Services. These injuries can be caused through a variety of mechanisms including scalds sustained when filling the bottle or scalds from leaking or rupture. The fuel poverty crisis started in February 2022 leading to an estimated six-fold increase in alternative sources of heating, in particular hot water bottles. In this study, we wish to understand the impact that this may have had upon burn injuries sustained by these products.</div></div><div><h3>Methods</h3><div>All hot water bottle (HWB)-related injuries sustained January 2014 - February 2023 were retrieved from the UK International Burn Injury Database (IBID). Data were collected on patient demographics, injury mechanism, anatomical location, and clinical outcomes. The data were collated and analysed; statistical analysis was performed using R StudioTM. Patient levelling costs were also incorporated to enable translation of these data into healthcare costs.</div></div><div><h3>Results</h3><div>A total of 5944 HWB-related burn injuries were recorded in the IBID database in England and Wales, from 2014 to 2023, with a mean of 594 (SD 146.2) burn injuries annually, costing an estimated £ 12.7 million. There were 423 burn injuries sustained from HWB in winter 2022 compared to 295 in winter 2021, representing a 43.4 % increase over one year, with a corresponding increase of 43.1 % in the number of patients managed in an outpatient setting. The largest increase in burn incidence between winter 2021 and winter 2022 was seen in children (0–16 years old) and older adults (greater than 65 years old) with a rise of 60.3 % (n = 41) and 68.5 % (n = 37) respectively.</div></div><div><h3>Conclusion</h3><div>Our epidemiological study on hot water bottle (HWB)-related burn injuries within the United Kingdom has shown that the dramatic rise in fuel prices, which sparked the fuel poverty crises, has coincided with a 43.4 % increase in HWB burns incidence on the health service in that year alone. This alarming rise in HWB-related injuries highlights the continued need for targeted public awareness campaigns to ensure a safe and proper use of these devices.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107275"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interaction between long non-coding RNA and micro RNA in hypertrophic scar formation 长非编码 RNA 与微 RNA 在肥厚性瘢痕形成中的相互作用
IF 3.2 3区 医学
Burns Pub Date : 2024-12-01 DOI: 10.1016/j.burns.2024.08.005
Hojat Eftekhari
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