Burns最新文献_第7页

World burn care and the multidisciplinary team 世界烧伤护理和多学科团队

IF 3.2 3区医学

Burns Pub Date : 2025-03-11 DOI: 10.1016/j.burns.2025.107453

Yangmyung Ma, Gemma Stewart, Elizabeth Chipp, Sarah Bache

引用次数: 0

Suprathel’s usability and effectiveness for the treatment of paediatric partial thickness burns: a 10-year retrospective cohort study Suprathel治疗小儿部分厚度烧伤的可用性和有效性：一项10年回顾性队列研究

IF 3.2 3区医学

Burns Pub Date : 2025-03-11 DOI: 10.1016/j.burns.2025.107451

Milly S van de Warenburg , Selafa El Yadari , Stefan Hummelink , Dietmar JO Ulrich , MLAW Vehmeijer-Heeman

{"title":"Suprathel’s usability and effectiveness for the treatment of paediatric partial thickness burns: a 10-year retrospective cohort study","authors":"Milly S van de Warenburg , Selafa El Yadari , Stefan Hummelink , Dietmar JO Ulrich , MLAW Vehmeijer-Heeman","doi":"10.1016/j.burns.2025.107451","DOIUrl":"10.1016/j.burns.2025.107451","url":null,"abstract":"<div><div>Suprathel has been introduced in our centre since 2014 for superficial to deep partial thickness burns. To evaluate healing outcomes and usability of Suprathel in our paediatric population, we conducted a retrospective cohort study, including all paediatric patients treated with Suprathel for burn wounds since its introduction. The studied population consisted of 92 patients, with a mean age of 4 years [3 months −17 years]. The median wound healing time for the entire cohort was 12.5 days, with no significant differences between the age groups. If wounds were found to be colonized during treatment, the majority of pathogens were Staphylococcus aureus (55.8 %). Seven percent of the patients required a split-thickness skin graft after approximately ten days. The use of Suprathel as epidermal dressing for treatment of partial thickness burns in the paediatric population demonstrates favourable adherence to the wound bed, and reduces the need for frequent dressing changes; the lack of increased wound infections underscore its benefits in paediatric burn care. Our findings suggest no significant differences in outcomes based on the timing of application, wound location, or wound bed preparation, and confirms its efficacy in mobile areas such as the hands.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 4","pages":"Article 107451"},"PeriodicalIF":3.2,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Confounders of the skin microbiome and wound healing in burn patients 烧伤患者皮肤微生物群与伤口愈合的混杂因素

IF 3.2 3区医学

Burns Pub Date : 2025-03-10 DOI: 10.1016/j.burns.2025.107450

Alireza Pourali, Shahab Aali, Amirhosein Kamrava

引用次数: 0

Have the recent advancements in wound repair and scar management technology improved the quality of life in burn patients? 最近伤口修复和疤痕管理技术的进步是否改善了烧伤患者的生活质量？

IF 3.2 3区医学

Burns Pub Date : 2025-03-07 DOI: 10.1016/j.burns.2025.107443

Bishara Atiyeh, Tarek F. El Hachem, Rawad Chalhoub, Saif E. Emsieh

{"title":"Have the recent advancements in wound repair and scar management technology improved the quality of life in burn patients?","authors":"Bishara Atiyeh, Tarek F. El Hachem, Rawad Chalhoub, Saif E. Emsieh","doi":"10.1016/j.burns.2025.107443","DOIUrl":"10.1016/j.burns.2025.107443","url":null,"abstract":"<div><h3>Background</h3><div>The negative physical and psychosocial impact of scars, in particular burn scars, has been well documented. Altered personal appearance together with impaired function related to pain, heat intolerance, and contracture formation may last a lifetime and eventually can lead to low self-esteem and poor social and psychological adjustments. Though most patients recover within the first years and many report generally good life satisfaction and moderate quality of life (QoL), some severely burned patients continue to report impaired QoL almost 10 years after injury. It is repeatedly mentioned in the literature that patients’ QoL and health-related quality of life (HRQoL) can be improved by improving wound healing and burn scar quality. Determining whether advances in burn wound healing and scar management modalities are positively impacting the lives of surviving patients is the aim of this review.</div></div><div><h3>Methods</h3><div>A systematic literature review was used to identify studies measuring QoL of patients surviving severe burn injuries following various interventions to improve burn wound healing and scar quality.</div></div><div><h3>Results</h3><div>A limited number of studies was identified. Given the limited available data, a narrative review approach including qualitative studies and reviews in addition to identifying common themes, trends, and gaps in the existing literature was deemed more appropriate for a comprehensive analysis.</div></div><div><h3>Conclusion</h3><div>The assumption that progress made in recent decades to improve burn wound healing and scar quality would improve QoL remains largely hypothetical. Except for functional release of burn scar contractures, improved scar aesthetic quality does not necessarily translate into improved QoL of surviving patients. Well-designed comparative studies are largely lacking.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 4","pages":"Article 107443"},"PeriodicalIF":3.2,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of lncRNA biomarkers for keloid diagnosis and functional characterization of CPEB2-AS1 用于瘢痕疙瘩诊断和CPEB2-AS1功能表征的lncRNA生物标志物鉴定

IF 3.2 3区医学

Burns Pub Date : 2025-03-05 DOI: 10.1016/j.burns.2025.107448

Shengjing Xu , Yali Jiang , Xianggong Zhu , Yanting Rao , Min Zhang , Yan Lu

{"title":"Identification of lncRNA biomarkers for keloid diagnosis and functional characterization of CPEB2-AS1","authors":"Shengjing Xu , Yali Jiang , Xianggong Zhu , Yanting Rao , Min Zhang , Yan Lu","doi":"10.1016/j.burns.2025.107448","DOIUrl":"10.1016/j.burns.2025.107448","url":null,"abstract":"<div><h3>Background</h3><div>Keloids are pathological scars marked by excessive tissue growth, and their diagnosis currently depends on clinical observation, lacking objective biomarkers. Although the regulatory role of long non-coding RNAs (lncRNAs) in various diseases has drawn attention, their function in keloids remains unclear.</div></div><div><h3>Methods</h3><div>This study employed high-throughput sequencing, bioinformatics analysis and machine learning algorithms to identify differentially expressed lncRNAs in keloid tissues and to construct a diagnostic model. The relationship between these lncRNAs and immune responses, as well as gene expression regulation, was explored through immune signature analysis and co-expression networks. The role of CPEB2-AS1 in keloids was investigated through expression validation, pan-cancer analysis and functional experiments.</div></div><div><h3>Results</h3><div>Four key differentially expressed lncRNAs were identified, enabling the development of an effective diagnostic model that distinguishes keloid tissues from healthy controls. Immune signature analysis revealed a positive correlation between CPEB2-AS1 and immune cell activity. Co-expression networks and functional enrichment analysis suggested that these lncRNAs may regulate RNA processing and nucleic acid binding. Expression validation and pan-cancer analysis confirmed their abnormal expression in keloids. Functional experiments demonstrated that CPEB2-AS1 significantly influences cell proliferation, migration, invasion and apoptosis.</div></div><div><h3>Conclusion</h3><div>This study identifies new molecular markers for the early diagnosis of keloids and highlights the potential role of CPEB2-AS1 in keloid progression, offering insights for future therapeutic strategies.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 4","pages":"Article 107448"},"PeriodicalIF":3.2,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143642454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Shah Suit – A bespoke dressing for paediatric patients with non-burn skin loss 沙阿套装-为非烧伤皮肤损失的儿科患者定制的敷料

IF 3.2 3区医学

Burns Pub Date : 2025-03-05 DOI: 10.1016/j.burns.2025.107441

Katherine Radcliffe, Adrian Karangura, Clare Rivers, Mamta Shah

引用次数: 0

Lateral thinking: different perspectives on burn care 横向思维：烧伤护理的不同观点

IF 3.2 3区医学

Burns Pub Date : 2025-03-04 DOI: 10.1016/j.burns.2025.107446

Muhammad Adil Abbas Khan, Yangmyung Ma

引用次数: 0

Dermatological diseases in conflict areas: A neglected crisis 冲突地区的皮肤病：被忽视的危机。

IF 3.2 3区医学

Burns Pub Date : 2025-03-04 DOI: 10.1016/j.burns.2025.107447

Suela Këlliçi, Entela Puca, Monika Fida, Edmond Puca, Najada Çomo

引用次数: 0

Coagulation abnormalities in major burn patients: Insights and future considerations 重大烧伤患者凝血异常：见解和未来的考虑

IF 3.2 3区医学

Burns Pub Date : 2025-02-28 DOI: 10.1016/j.burns.2025.107445

Amirhosein Kamrava , Shahab Aali

引用次数: 0

Preparation and assessment of polylactic acid-curcumin nanofibrous wound dressing containing silver nanoparticles for burn wound treatment 含纳米银聚乳酸-姜黄素纳米纤维创面敷料的制备及评价

IF 3.2 3区医学

Burns Pub Date : 2025-02-27 DOI: 10.1016/j.burns.2025.107442

Mehri Moayedi , Tahmineh Ahmadi , Vahid Nekouie , Majid Taghian Dehaghani , Shahrokh Shojaei , Soheila Zamalui Benisi , Hamid Reza Bakhsheshi-Rad

{"title":"Preparation and assessment of polylactic acid-curcumin nanofibrous wound dressing containing silver nanoparticles for burn wound treatment","authors":"Mehri Moayedi , Tahmineh Ahmadi , Vahid Nekouie , Majid Taghian Dehaghani , Shahrokh Shojaei , Soheila Zamalui Benisi , Hamid Reza Bakhsheshi-Rad","doi":"10.1016/j.burns.2025.107442","DOIUrl":"10.1016/j.burns.2025.107442","url":null,"abstract":"<div><div>This study aims to produce and evaluate nanofibrous wound dressings through the electrospinning method, utilizing polylactic acid (PLA), curcumin (Cur), and silver nanoparticles (AgNPs). For this purpose, five types of wound dressings with PLA, PLA+Cur, PLA+Cur+ 1 %AgNPs, PLA+Cur+ 2 %AgNPs and PLA+Cur+ 3 %AgNPs were produced using the electrospinning method. Analysis of the Fourier transform infrared spectroscopy and scanning electron microscopic observations indicated successful fabrication, with nanometer diameters achieved in all electrospun samples. Examination of water absorption of wound dressings revealed that over 40 h the electrospun samples had variable water absorption between 0 % and 0.25 %. The results of the curcumin release test over one week showed that the nanofibers with PLA+Cur+ 2 %AgNPs exhibited the lowest release rate, while those with PLA+Cur+ 3 %AgNPs showed the highest release. Assessment of mechanical properties revealed that the tensile strength of the nanofibers increased by adding curcumin to polylactic acid, while the addition of a high content of AgNPs led to a decrease in tensile strength. Also, the PLA+Cur dressing demonstrated 84.06 % and the PLA+Cur+ 3 %AgNPs dressing exhibited 99.12 % antibacterial properties. The cell culture test demonstrated that the incorporation of curcumin and AgNPs increasedboth the growth and proliferation, as well as the adhesion on the nanofibrous wound dressing. Thus, the PLA+Cur+ 1 %AgNPs nanofibrous scaffold, as a multipurpose dressing, presented considerable promise for wound healing and burn treatment.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 4","pages":"Article 107442"},"PeriodicalIF":3.2,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143619305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0