{"title":"Stigma and discrimination in healthcare: Challenges faced by burn patients in India","authors":"Pratishtha Singh , Jagnoor Jagnoor , Mohammed Fahud Khurram , Brijesh Mishra , Vikash Ranjan Keshri","doi":"10.1016/j.burns.2025.107566","DOIUrl":"10.1016/j.burns.2025.107566","url":null,"abstract":"<div><h3>Background</h3><div>Burn injuries are a significant global public health concern, particularly in low- and- middle-income countries like India. These patients often face economic hardships, vocational limitations, and social exclusion even before sustaining their injuries. The resulting disfigurement, disability, and scarring from burns lead to increased social stigma and discrimination, exacerbating mental health concerns among survivors. However, we could not find any existing research exploring this phenomenon in health facility settings. This study aims to investigate the presence and manifestations of stigma and discrimination experienced by burn patients in healthcare institutions in India.</div></div><div><h3>Methods</h3><div>A qualitative inquiry was conducted in Uttar Pradesh, India, between June and December 2023. A total of 18 face-to-face in-depth interviews were conducted with participants, including seven burn patients, eight healthcare providers, and three legal professionals who work for the welfare of burn survivors. Participants were selected through purposive sampling. The data was analysed in NVivo using thematic analysis.</div></div><div><h3>Results</h3><div>Three key themes were identified. The first theme, ‘Health system factors contributing to stigma’ highlights institutional barriers such as an overburdened health system, resource constraints, and the absence of guidelines. The second theme of ‘Patient experiences of stigma in health facilities’ delves into patient-provider interactions, instances of physical and mental abuse, and stigma intersectionality. Lastly, the third theme, ‘Possible ways for promoting inclusivity and reducing stigma’ discusses multistakeholder sensitization and policy reforms for discrimination-free care. In addition, we also use the Health Stigma and Discrimination framework to interpret stigma around burns, its outcome, and impact.</div></div><div><h3>Conclusion</h3><div>This study provides crucial insights into the multifaceted challenges of stigma and discrimination faced by burn patients within healthcare facilities. Our findings suggest an urgent need for reform within the health systems by developing policies and guidelines around discrimination-free healthcare--strengthening public-sector burn care, enhancing rehabilitation services, raising awareness of burns, and improving the social reintegration of survivors.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107566"},"PeriodicalIF":3.2,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144213399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From cadaveric donation to cryopreserved total skin allografts: Transforming the Chilean skin donation model","authors":"Marcelo Fonseca , Aldo Cañete , Luana Mandriaza , Jennifer Gómez , Jaume Masiá , Katherine Marcelain , Dino Ibaceta , Cristian Erazo , Brenda Gámez , Carolina Soto , Cristóbal Valdés","doi":"10.1016/j.burns.2025.107563","DOIUrl":"10.1016/j.burns.2025.107563","url":null,"abstract":"<div><h3>Background</h3><div>The clinical utility of skin allografts (SA) is well established. However, the donation and procurement of cadaveric skin—historically the primary source of SA—remain limited in many countries. A skin donation model based on the use of excess surgical tissue from body contouring procedures was introduced and compared with the traditional cadaveric donation model.</div></div><div><h3>Methods</h3><div>A retrospective review of skin donations in Chile was conducted over two periods (2017–2019 and 2022–2024), analyzing the performance and characteristics of two donation pathways: cadaveric and living donors.</div></div><div><h3>Results</h3><div>During the first period (2017–2019), four cadaveric donors provided a total of 10,959 cm² of skin. In the second period (2022–2024), 353 donors contributed 153,585 cm² of skin, of which 348 were living donors (131,997 cm²) and five were cadaveric (21,588 cm²).</div></div><div><h3>Conclusions</h3><div>Initially conceived as a complementary strategy, the living donor model has evolved to become the primary source of skin allografts in Chile. This approach significantly increases the availability of SA, broadens therapeutic indications, and promotes the concept of transforming excess surgical tissue into valuable therapeutic resources. Moreover, it enables the production of cryopreserved full-thickness skin allografts (CTSA), which serve not only as temporary wound coverage but also as dermal regenerative scaffolds, particularly beneficial in the treatment of burns affecting functionally and aesthetically critical areas. This new paradigm supports a more accessible and sustainable culture of skin donation while offering promising benefits for regenerative burn care.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107563"},"PeriodicalIF":3.2,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144213465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-24DOI: 10.1016/j.burns.2025.107560
Noora-Ilona Lahdenperä , Andrew Lindford , Hannu Kautiainen , Jyrki Vuola , Jussi P. Repo
{"title":"Long-term health-related quality of life after a deep second- or third-degree burn treated with skin grafting","authors":"Noora-Ilona Lahdenperä , Andrew Lindford , Hannu Kautiainen , Jyrki Vuola , Jussi P. Repo","doi":"10.1016/j.burns.2025.107560","DOIUrl":"10.1016/j.burns.2025.107560","url":null,"abstract":"<div><h3>Background</h3><div>As burns are known to have a negative impact on the burn victim’s quality of life, the health-related quality of life (HRQoL) is a key outcome in the evaluation of burn treatment. In recent years there has been increasing interest in the use of HRQoL instruments after burn injury. The aim of this study was to assess whether there is a correlation between the HRQoL and the total body surface area (TBSA)% burned and also to assess correlation between the SCAR-Q scores and the TBSA% burned in deep burns requiring skin grafting.</div></div><div><h3>Methods</h3><div>Participants were adult burn patients treated in the Helsinki Burn Centre between 2006 and 2017 with skin grafting after deep second- or third-degree burns. Participants completed the general HRQoL 15D instrument and the patient-reported scar outcome measure SCAR-Q.</div></div><div><h3>Results</h3><div>194 participants were divided into three groups according to the burn TBSA%: small burns (<10 %), moderate burns (10–20 %) and large burns (>20 %). The total HRQoL score after small burns did not differentiate from the reference population, even though there was a statistically significant difference in two domains (depression and distress). HRQoL measured with the 15D instrument was worse for moderate burns in half of the domains and for large burns in most of the domains (11/15) in comparison with the reference population. Small burns scored the best and large burns the worst in every SCAR-Q subscale.</div></div><div><h3>Conclusion</h3><div>There is a negative correlation between both the HRQoL and SCAR-Q scores in relation to the burn size in deep second- and third-degree burns. Small deep burns did not appear to affect the total HRQoL, but with moderate and large deep burns the HRQoL was impaired.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107560"},"PeriodicalIF":3.2,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144166656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-22DOI: 10.1016/j.burns.2025.107552
Shraddha Namdeo , Monika Vishwakarma , Tanweer Haider , Sushil K. Kashaw , Vandana Soni
{"title":"Repurposing verapamil hydrochloride with niosomal gel technology: Enhanced efficacy and skin penetration in hypertrophic scars","authors":"Shraddha Namdeo , Monika Vishwakarma , Tanweer Haider , Sushil K. Kashaw , Vandana Soni","doi":"10.1016/j.burns.2025.107552","DOIUrl":"10.1016/j.burns.2025.107552","url":null,"abstract":"<div><div>Hypertrophic scars arising from abnormal wound healing after burns, trauma, or surgery present challenges for their effective treatment. Verapamil hydrochloride (VHCl), a calcium channel blocker primarily used in cardiovascular diseases, has been proposed as a niosomal gel for topical hypertrophic scar treatment. VHCL stimulates procollagenase synthesis, induces actin filament depolymerization, and reduces fibrous tissue production, thus making it a promising candidate for scar therapy. Prior to formulation, FT-IR spectroscopy was performed to assess drug and excipient compatibility. VHCl niosomes were prepared using the thin-film hydration technique with Span-40 and cholesterol in a 7:3 molar ratio. The characterization included entrapment efficiency (%EE), vesicle size, and surface morphology. Optimized niosomes were incorporated into a gel, and in <em>in-vitro</em> drug release and stability studies were conducted. An <em>in-vivo</em> study was conducted using a rabbit model to assess formulation efficacy. Optimized VHCl niosomal formulations with high entrapment efficiency (%EE) of 71.62 % and a small vesicle size of 180 nm were used for characterization, <em>in-vitro</em> and <em>in-vivo</em> evaluations. The vesicles displayed a monodisperse distribution, spherical and irregular morphology under TEM, and good stability for 60 days at room and refrigerated temperatures. The lyophilized formulation incorporated into the silicone gel exhibited optimal pH, thixotropic rheological behavior, and sustained VHCl release for up to 48 h. <em>In-vivo</em> studies on a rabbit ear model revealed enhanced efficacy, reducing hypertrophic scar diameter from 7 mm to 1.9 mm after 28 days. The combination of VHCl-loaded niosomal gels demonstrated improved permeation and synergistic effects, enhancing the safety and efficacy of long-term VHCl treatment.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107552"},"PeriodicalIF":3.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-22DOI: 10.1016/j.burns.2025.107546
Martin Zielina , Dominika Matysková , Jiří Štětinský , Robert Zajíček , Jaroslava Raudenská , Alena Javůrková , Kristína Sakmárová , Martin Modrák
{"title":"Translation, adaptation, and psychometric evaluation of the Burn-Specific Pain Anxiety Scale (BSPAS) for Czech patients with burn injuries","authors":"Martin Zielina , Dominika Matysková , Jiří Štětinský , Robert Zajíček , Jaroslava Raudenská , Alena Javůrková , Kristína Sakmárová , Martin Modrák","doi":"10.1016/j.burns.2025.107546","DOIUrl":"10.1016/j.burns.2025.107546","url":null,"abstract":"<div><div>This study aimed to adapt the Burn-Specific Pain Anxiety Scale (BSPAS) for use in the Czech language and evaluate its validity and reliability. Conducted across three university hospitals in the Czech Republic—Prague, Brno, and Ostrava—from September 2022 to February 2024, the study involved 203 inpatients and outpatients from burn units who met inclusion criteria and consented to participate. The adaptation process included rigorous analysis of validity and reliability, employing language, content, and construct validity assessments. Language validity was ensured through back translation, whereas content validity was confirmed through expert evaluations. Exploratory factor analysis revealed at least a two-factor structure with satisfactory factor loading. Loading of factors to questions was consistent between BSPAS-9 and BSPAS-5. Confirmatory factor analysis further substantiated the model fit for both five- and nine-item versions (RMSEA 0.06 and 0.1 respectively). Internal consistency was assessed using item-total correlation, yielding acceptable results (range 0.63–0.82 for nine items and 0.71–0.82 for five items). Cronbach's alpha coefficients were 0.94 for the nine-item version and 0.91 for the five-item version. These findings indicate that the Czech version of the BSPAS is a valid and reliable tool for assessing pain-related anxiety in patients with burns. Additionally, we show that in our population, the information from the nine-item version is well captured by the five-item version and pain alone explains most of the variance in BSPAS scores.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107546"},"PeriodicalIF":3.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-22DOI: 10.1016/j.burns.2025.107558
Adi Maisel Lotan , Ofer Merin , Yaron Shoham , Ronen Toledano , David Ben Ari , Muhamad Jaber , Rachel Havivi , Eliran Jacobi , Subhi Hakrush , Michael Dubilet , Ron Gal , Yasin Mamdoh , Shai Schul , Njde Hambarchian , Greta Harutyunyan , Yoav Gronovich
{"title":"The Israeli mission to the 2023 Armenian burn mass casualty incident – Lessons learned","authors":"Adi Maisel Lotan , Ofer Merin , Yaron Shoham , Ronen Toledano , David Ben Ari , Muhamad Jaber , Rachel Havivi , Eliran Jacobi , Subhi Hakrush , Michael Dubilet , Ron Gal , Yasin Mamdoh , Shai Schul , Njde Hambarchian , Greta Harutyunyan , Yoav Gronovich","doi":"10.1016/j.burns.2025.107558","DOIUrl":"10.1016/j.burns.2025.107558","url":null,"abstract":"<div><h3>Background</h3><div>The Israeli mission to Armenia was deployed to assist in a mass casualty burn incident caused by an explosion in Nagorno-Karabakh County, Armenia. The explosion caused over 220 deaths and approximately 300 injured. The objective of this manuscript is to report the lessons learned from this mission.</div></div><div><h3>Methods</h3><div>An advance team of plastic surgeons was deployed to Armenia to assess local needs in preparation for the arrival of international mission groups: the quantity and location of patients, severity of injuries and availability of surgical and medical supplies. This team was to operate alongside other international burn teams.</div></div><div><h3>Results</h3><div>Patients were evacuated to local hospitals. Over 200 patients were hospitalized in five centers in Yerevan, including about half in the National Burn Center. Our teams performed forty-two surgeries in four days including debridement of burns, dressing changes and reconstructions with skin grafts and dermal substitutes. Finally, we helped define goals for future teams with stress on patient care and rehabilitation.</div></div><div><h3>Conclusion</h3><div>Burns require prolonged multidisciplinary treatment and resources. Facing a mass casualty event, it is important to prepare ahead, define relevant needs and make a game plan according to which patients will receive the best possible care relative to the situation.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107558"},"PeriodicalIF":3.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of social support perceived by parents of child burn victims on their care burden and anxiety","authors":"Mehmet Emin Düken , Ayşe Arıcıoğlu Sülün , Emriye Hilal Yayan , Mürşide Zengi̇n , Tekcan Sevgi̇","doi":"10.1016/j.burns.2025.107525","DOIUrl":"10.1016/j.burns.2025.107525","url":null,"abstract":"<div><h3>Purpose</h3><div>The aim of this study is to examine the effect of perceived social support on the caregiving burden and anxiety of parents of children with burn injuries.</div></div><div><h3>Material and Methods</h3><div>This is a correlational descriptive study. The study was conducted with parents of 52 children who were admitted and treated in a paediatric burn clinic at a university hospital between January and December, 2019. The Zarit Care Burden Scale, the Multidimensional Scale of Perceived Social Support, and the State Anxiety Scale were used in the study. Path analysis was performed with observed variables, and structural equation model (SEM) was constructed using Amos programme.</div></div><div><h3>Results</h3><div>The mean age of the parents was 30.94 ± 7.33 years. In the study, the cause of burns in 55.8 % of the children was contact with flame (oil, thinner, and gas) and it was found that 82.7 % of the children had third degree burns and 65.4 % had second degree burns. A positive significant correlation was found between anxiety and caregiving burden, but a negative correlation was found between anxiety and parental social support.</div></div><div><h3>Conclusions</h3><div>The study found that the level of anxiety and caregiving burden of parents of children with burns increased as their social support decreased. In line with the results of our study, it is seen that health professionals (doctors, nurses, psychologists, social workers) working in paediatrics can involve parents in care interventions by assessing their social support, caregiving burden, and anxiety.</div></div><div><h3>Practice Implications</h3><div>It has been observed that the care burden and anxiety levels of burned children increase as the social support they receive from their parents decreases. Healthcare professionals (doctors, nurses, psychologists, social workers) working in this clinic should provide social, emotional, and psychological support to parents and share the burden of care. It has been shown that as social support increases, caregiving and anxiety levels can improve significantly.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107525"},"PeriodicalIF":3.2,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-21DOI: 10.1016/j.burns.2025.107559
Mehdi Ayaz
{"title":"Addressing common reasons for rejection of burn research articles","authors":"Mehdi Ayaz","doi":"10.1016/j.burns.2025.107559","DOIUrl":"10.1016/j.burns.2025.107559","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107559"},"PeriodicalIF":3.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144154519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-21DOI: 10.1016/j.burns.2025.107548
Medha Vallurupalli , Nikhil D. Shah , Samhitha Yadalla , Raj M. Vyas
{"title":"Promoting patient health literacy in burn care through artificial intelligence language learning models: A study of text analysis and simplification","authors":"Medha Vallurupalli , Nikhil D. Shah , Samhitha Yadalla , Raj M. Vyas","doi":"10.1016/j.burns.2025.107548","DOIUrl":"10.1016/j.burns.2025.107548","url":null,"abstract":"<div><div>Health literacy is essential in patient care, especially in burn treatment, where understanding care information can significantly influence recovery outcomes. Despite national guidelines recommending that patient education materials be written at a 6th- to 8th-grade reading level, many resources exceed this complexity, exacerbating poor health literacy and patient outcomes. This study investigates the effectiveness of artificial intelligence language learning models in simplifying patient-facing burn care information to adhere to these readability standards. Fifteen excerpts from academic institutions' burn care materials were evaluated for readability using a traditional readability calculator and four AI models: ChatGPT 4o, Microsoft Copilot, Gemini, and Meta AI. The traditional readability calculator provided a baseline score, which was compared to the scores from the AI models. Results indicated that ChatGPT 4o and Microsoft Copilot had readability scores that were comparable to the readability scores provided by the traditional calculator. Additionally, when tasked with simplifying the texts, Microsoft Copilot, Gemini, and Meta AI reduced the readability scores to within the desired 6th to 8th-grade level. These findings suggest that AI models, particularly Microsoft Copilot, Gemini, and Meta AI, can effectively simplify medical texts, making them more accessible to patients. However, clinician oversight is necessary to ensure the accuracy and appropriateness of the simplified materials, promoting better health literacy and patient outcomes in burn care.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107548"},"PeriodicalIF":3.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144195099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BurnsPub Date : 2025-05-21DOI: 10.1016/j.burns.2025.107556
Márcia Pereira Silva , Joana Vala , João Sousa , Joana Ferreira Teixeira , Helga Rafael Henriques
{"title":"Incidence and delirium risk factors in burn patients: A prospective cohort study","authors":"Márcia Pereira Silva , Joana Vala , João Sousa , Joana Ferreira Teixeira , Helga Rafael Henriques","doi":"10.1016/j.burns.2025.107556","DOIUrl":"10.1016/j.burns.2025.107556","url":null,"abstract":"<div><h3>Background</h3><div>Delirium is a neurocognitive syndrome caused by systemic disturbances, leading to impaired attention, awareness, and/or cognition. It poses a significant risk of comorbidities, mortality, prolonged hospitalization, and increased healthcare costs. The challenges in delirium management, follow-up, and rehabilitation, arising from complex chronic conditions and long-term complications after severe burns, highlight the urgent need for more research in this area. Thus, this study aims to investigate the incidence of delirium and the risk factors specific to this population.</div></div><div><h3>Methods</h3><div>This analytical observational prospective cohort study was conducted between August 2022 and January 2024. Adults (18 years and older) admitted to a single burn unit with a confirmed burn injury were included, regardless of burn severity. Sociodemographic and clinical variables included age, sex, extent of burn, and prior health status. Delirium assessment was made using the CAM-ICU scale at least twice a day. The primary outcome was the incidence of delirium and its risk factors, with secondary outcomes including the onset and duration of delirium episodes.</div></div><div><h3>Results/Discussion</h3><div>The sample consisted of 50 patients, with a delirium incidence of 52 %. Burn patients admitted to the burn unit developed delirium an average of 11.81 days (95 % CI=7.09–16.52) after hospitalization, with an average duration of 11.5 days (95 % CI = 7.28–15.72). Age was the only predisposing risk factor that emerged (p = 0.0141). Five variables emerged as precipitating risk factors in bivariate analyses: total surface burn area (TSBA) (p = 0.026), surgery (p = 0.0438), mechanical ventilation (p < 0.001), opioid infusion use (p < 0.001), and infection (p < 0.001). However, in multivariate Cox regression analyses, only mechanical ventilation remained statistically significant as a risk factor for delirium (HR=8.017; 95 % CI = 1.926 – 33.368; p = 0.004).</div></div><div><h3>Conclusion</h3><div>This study highlights mechanical ventilation as a critical risk factor contributing to the high incidence of delirium among burn patients. Early identification and management of risk factors—mainly mechanical ventilation, but also TSBA, surgery, opioid infusion use, and infection—can guide targeted interventions to improve patient outcomes and mitigate the impact of delirium on recovery.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 6","pages":"Article 107556"},"PeriodicalIF":3.2,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144154527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}