Burns最新文献

{"title":"Cement burns among manual labourers in the UK: An urgent call for improved safety measures and education","authors":"Dana Elsalman , Omar Alnobani, Karl Walsh","doi":"10.1016/j.burns.2024.09.001","DOIUrl":"10.1016/j.burns.2024.09.001","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107262"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing thromboembolism prevention and management in burn patients","authors":"Mahta Moghaddam Ahmadi, Moein Moghaddam Ahmadi","doi":"10.1016/j.burns.2024.07.012","DOIUrl":"10.1016/j.burns.2024.07.012","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107208"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141707267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation of a standardized self-reported cost questionnaire specific for the severe burn injury population (BI-CoPaQ)","authors":"Maria-Eugenia Espinoza-Moya ,&nbsp;Maude Laberge ,&nbsp;Laurianne Bélanger ,&nbsp;Sue-Ling Chang ,&nbsp;Thomas G. Poder ,&nbsp;Véronique J. Moulin ,&nbsp;Lucie Germain ,&nbsp;Chanel Beaudoin Cloutier ,&nbsp;Jason Robert Guertin","doi":"10.1016/j.burns.2024.07.008","DOIUrl":"10.1016/j.burns.2024.07.008","url":null,"abstract":"<div><div>Severe burn injuries (SBIs) are known to pose a significant burden on patients, caregivers, and the healthcare system. Yet, scarce data on the short and long-term clinical and economic impacts of these injuries limit the development of evidence-informed strategies and policies to better care for these patients. To fill in this gap, we adapted a previously validated self-reported out-of-pocket cost measurement questionnaire, the Cost for Patients Questionnaire (CoPaQ), to the severe burn injury survivor context. We conducted one-on-one cognitive semi-structured interviews with burn injury survivors, their caregivers, and healthcare providers to identify elements of the CoPaQ’s structure and content that needed to be revised to adapt to the specific health care trajectory, service utilization, needs and expenses incurred by adult severe burn injury survivors and their caregivers. Summative content analysis was used to identify items needing to be modified, deleted, or added. Based on this information, a preliminary version of a Burn Injury Cost for Patients Questionnaire (BI-CoPaQ) was developed and subsequently pre-tested on a small sample of SBIs survivors. Further validation of this tool will be required before BI-CoPaQ can be used as the standard for the estimation of the financial burden of SBIs in this population.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107204"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141692268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between job satisfaction and motivation levels of nurses working in burn units","authors":"A. Kabuk ,&nbsp;P. Ongün","doi":"10.1016/j.burns.2024.07.015","DOIUrl":"10.1016/j.burns.2024.07.015","url":null,"abstract":"<div><h3>Background</h3><div>For nurses working in specialized units such as burn units, having adequate levels of job satisfaction and motivation is crucial for enhanced productivity in order to maintain quality nursing care.</div></div><div><h3>Methods</h3><div>A cross-sectional, descriptive, correlational design was used in the study. The study aimed to investigate the job satisfaction and motivation levels of nurses working in burn units, the relationship between job satisfaction and motivation levels, and the influencing factors. The study sample consisted of 73 nurse managers/clinicians who worked in burn services or intensive care units in September and December 2023. The data were collected with “Demographic and work characteristics form,” “Job Satisfaction Scale for Nurses (JSSN)”, “Nurse Job Motivation Scale (NJMS)”. Data were analyzed using Independent Samples T-test, One-Way ANOVA, and Mann-Whitney U tests to compare the descriptive characteristics of nurses and the scale scores. Correlation and regression analyses were conducted to reveal the relationship between the descriptive characteristics and scale scores of the nurses.</div></div><div><h3>Results</h3><div>The mean age of the nurses was 30.26 ± 7.99 years, and 60.3 % were bachelor's degree graduates. The nurses had an average of 8.64 ± 8.25 years of experience in the profession and an average of 4.77 ± 5.39 years in the burn unit. The total score average for the NJMS was found to be 66.49 ± 5.56, and the JSSN score average was 3.46 ± 0.58. A weak negative relationship was found between the JSSN subscale \"Suitable Support from Seniors\" and age (p &lt; 0.05), \"Perceived importance at the job\" and the working years in the burn unit (p &lt; 0.05).</div></div><div><h3>Conclusions</h3><div>A positive correlation was observed between job satisfaction and job motivation of the nurses. If older nurses cannot get support from their supervisors, their satisfaction will be decreased. In addition, if more experienced nurses in the burn unit do not feel importance on the job, their satisfaction will be decreased.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107211"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and timing of infectious complications from battlefield-related burn injuries","authors":"Matthew R. Geringer ,&nbsp;Laveta Stewart ,&nbsp;Faraz Shaikh ,&nbsp;M. Leigh Carson ,&nbsp;Dan Lu ,&nbsp;Leopoldo C. Cancio ,&nbsp;Jennifer M. Gurney ,&nbsp;David R. Tribble ,&nbsp;John L. Kiley","doi":"10.1016/j.burns.2024.07.004","DOIUrl":"10.1016/j.burns.2024.07.004","url":null,"abstract":"<div><h3>Background</h3><div>Infections are the most frequent complication and cause of mortality in burn patients. We describe the epidemiology and outcomes of infections among deployed U.S. military personnel with burns.</div></div><div><h3>Methods</h3><div>Military personnel who sustained a burn injury in Iraq or Afghanistan (2009–2014) and were admitted to the Burn Center at U.S. Army Institute of Surgical Research at Brooke Army Medical Center were included in the analysis.</div></div><div><h3>Results</h3><div>The study population included 144 patients who were primarily young (median 24 years) males (99 %) with combat-related burns (62 %) sustained via a blast (57 %), resulting in a median total body surface area burned (TBSA) of 6 % (IQR 3–14 %). Twenty-six (18 %) patients developed infections, with pneumonia being the predominant initial infection (= 16), followed by skin and soft-tissue infections (SSTI, = 6), bloodstream infections (BSI, = 3), and intra-abdominal infections (IAI, = 1). Initial infections were diagnosed at a median of 4 days (IQR 3–5) post-injury for pneumonia, 7 days (IQR 4–12) for SSTIs, 7 days (IQR 6–7) for BSI, and 17 days for IAI. Patients with infections were more severely injured with greater TBSA (median 31 % vs 5 %), more inhalation injury (38 % vs 12 %), and longer time to definitive surgical management (median of 34 days vs 9) compared to those who did not develop infections (p &lt; 0.001). Among patients with inhalation injury, a higher proportion developed pneumonia (42 %) compared to those without inhalation injury (5 %; p &lt; 0.001). Five patients developed an invasive fungal infection. Gram-negative bacilli were most frequently recovered, with 32 % of Gram-negative isolates being multidrug-resistant. Four patients died, of whom all had ≥ 4 infections.</div></div><div><h3>Conclusions</h3><div>Military personnel with burn injuries who developed infections were more severely injured with greater TBSA and inhalation injury. Improved understanding of risk factors for burn-related infections in combat casualties is critical for effective management.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107200"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141694257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Administration of Burns First Aid Treatment to Aboriginal and Torres Strait Islander children in community settings","authors":"Julieann Coombes ,&nbsp;Holger Möeller ,&nbsp;Sarah Fraser ,&nbsp;Hayley Williams ,&nbsp;Kate Hunter ,&nbsp;Rebecca Ivers ,&nbsp;Andrew JA Holland ,&nbsp;Tamara Mackean ,&nbsp;Patrick Sharpe ,&nbsp;Courtney Ryder","doi":"10.1016/j.burns.2024.07.023","DOIUrl":"10.1016/j.burns.2024.07.023","url":null,"abstract":"<div><h3>Objective</h3><div>This paper investigates Burn First Aid Treatment (BFAT) provided to Aboriginal and Torres Strait Islander children in Australia at the scene of injury using data from a population-based cohort study.</div></div><div><h3>Study Design</h3><div>The participants were 208 Aboriginal and Torres Strait Islander children aged &lt; 16 years who sustained a burns injury between 2015–2018, and their carers. The primary outcome measure was gold standard BFAT, (defined as at least 20 min of cool, running water within 3 h of the injury); additional measures included type of first aid, length of first aid provided, and carer's knowledge of first aid.</div></div><div><h3>Results</h3><div>Of the 208 caregivers, 168 provided open-ended responses that indicated first aid was applied to their child; however, only 34 received gold standard BFAT at the scene of the injury, 110 did not receive correct BFAT, and 24 were unsure what first aid was applied.</div></div><div><h3>Conclusion</h3><div>This study highlights an important need for communities to have access to appropriate evidence-based and co-designed BFAT education and training.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107219"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the heat source affect the risk of wound infection in children with scalds?","authors":"Matilda Karlsson ,&nbsp;Arthur Johnson ,&nbsp;Ingrid Steinvall ,&nbsp;Laura Pompermaier","doi":"10.1016/j.burns.2024.08.023","DOIUrl":"10.1016/j.burns.2024.08.023","url":null,"abstract":"<div><h3>Introduction</h3><div>Scalds are the leading cause of burns in children younger than 5 years of age with most being related to food preparation and consumption. Hot substances causing scalds have different degrees of viscosity varying from low (liquid substances, such as water), to high (semi-solids or solids, such as oils or grease). It is still underknown whether heat substances with different viscosities are associated with varying risks of developing burn wound infections (BWI). The aim of this study was to investigate the association between heat sources of different viscosities and development of BWI within the first week after injury in children with scalds.</div></div><div><h3>Method</h3><div>Children 5 years and younger of age admitted at the Linköping Burn Center for new scalds between 2015 and 2020 were included. Data source for the study population was the Burn Unit Database. BWI was defined as fulfilment of at least two ABA criteria at the time of systemic antibiotic therapy (AB) initiation between day 2–7 following scald. Medical record review was undertaken to identify the heat source causing the scald, BWI criteria, and the use of AB. Legal guardians were contacted in cases in which information was missing. Logistic regression was used to analyse the association between heat source and development of BWI.</div></div><div><h3>Result</h3><div>The study population consisted of 271 children, median age was 1.5 years, 61 % were boys, median burn size was 3.5 % of the total body surface area (TBSA), 10 (4 %) had a full thickness burn. BWI were identified in 69 (26 %) of the children. Most scalds were caused by contact with hot liquids (n=184), followed by semisolids (n=52) and solids (n=35). The logistic regression model showed that the size of the burn (TBSA) was associated with BWI, while type of heating agent was not.</div></div><div><h3>Conclusion</h3><div>Our results indicate that the viscosity of the heat source does not affect the risk of wound infection in children with scalds; only the size of the area burned was an independent factor for BWI.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107257"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential therapeutic effects of topical recombinant human erythropoietin on burn wound healing: A preliminary randomized double-blind controlled clinical trial","authors":"Fatemeh Saghafi ,&nbsp;Farhad Mohammadi ,&nbsp;Farahnaz Hoseinzade ,&nbsp;Maryam Jafarpoor ,&nbsp;Mohammad Jalili Manesh ,&nbsp;Adeleh Sahebnasagh","doi":"10.1016/j.burns.2024.09.004","DOIUrl":"10.1016/j.burns.2024.09.004","url":null,"abstract":"<div><h3>Background</h3><div>Burn injuries can cause significant mortality and morbidity. This study aimed to evaluate the efficiency of topical recombinant human erythropoietin (rhEPO) on enhancing burn wound healing.</div></div><div><h3>Methods</h3><div>In this randomized double-blind controlled clinical trial, we enrolled 40 participants aged 18 years and older who were referred to a burn center during the first 24 h of burning. The participants with no concurrent comorbidities had superficial and deep second-degree burns, no respiratory burns, no face and perineum burns, no keloid formation, or a healed, fully epithelialized, hypertrophic burn scar. Topical rhEPO or nitrofurazone/Vitamin A was administered every other day, and the patients were scheduled for follow-up visits to receive wound cleansing, debridement, and dressing changes. Burn wound healing response to treatment was measured as the study main outcome.</div></div><div><h3>Results</h3><div>At the second follow-up visit, all parameters were significantly lower in the rhEPO group compared with the control group except for itchiness. The results of the next two follow-up sessions were also the same. The total value of the modified Vancouver Scar Scale (VSS) at days 5, 7, and 14 was significantly lower in the rhEPO group compared with the routine of care group.</div><div>Trial Registry Date: 2022–03-02, Trial Registry number: IRCT20190810044500N23</div></div><div><h3>Conclusions</h3><div>The results of the present study suggested that topical rhEPO is a potential option in burn wounds and patient satisfaction, without causing intolerable side effects.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107265"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single-cell sequencing analysis and bulk-seq identify IGFBP6 and TNFAIP6 as novel differential diagnosis markers for postburn pathological scarring","authors":"Chi Zhong ,&nbsp;Ke Shi,&nbsp;Peiting Li,&nbsp;Xiaohui Qiu,&nbsp;Xianrui Wu,&nbsp;Shuyue Chen,&nbsp;Yang Liu,&nbsp;Fuying Li,&nbsp;Zitong Zhao,&nbsp;Jianda Zhou,&nbsp;Geao Liang,&nbsp;Dan Xu","doi":"10.1016/j.burns.2024.08.021","DOIUrl":"10.1016/j.burns.2024.08.021","url":null,"abstract":"<div><h3>Background</h3><div>If not accurately diagnosed and treated, postburn pathological scars, such as keloids and hypertrophic scars, can lead to negative clinical outcomes. However, differential diagnosis at the molecular level for postburn pathological scars remains limited. Using single-cell sequencing analysis, we investigated the genetic nuances of pathological scars at the cellular level. This study aimed to identify molecular diagnostic biomarkers to distinguish between postburn keloids and hypertrophic scars.</div></div><div><h3>Methods</h3><div>Single-cell sequencing, differential expression, and weighted co-expression network analyses were performed to identify potential key genes for discriminating between keloids and hypertrophic scars. Postburn clinical samples were collected from our centre to validate the expression levels of the identified key genes.</div></div><div><h3>Results</h3><div>Single-cell sequencing analysis unveiled 29 and 30 cell clusters in keloids and hypertrophic scars, respectively, predominantly composed of fibroblasts. Bulk differential gene analysis showed 96 highly expressed genes and 69 lowly expressed genes in keloids compared to hypertrophic scars. By incorporating previous research, Gene Set Enrichment Analysis was conducted to select fibroblasts as the focus of research. According to the single-cell data, 301 genes were stably expressed in fibroblasts from both types of pathological scars. Consistently, Weighted Gene Co-expression Network Analysis revealed that the blue module genes were mostly hub genes associated with fibroblasts. After intersecting fibroblast-related genes in single-cell data, Weighted Gene Co-expression Network Analysis-hub module genes, and bulk differential expression genes, insulin-like growth factor binding protein 6 and tumour necrosis factor alpha-induced protein 6 were identified as key genes to distinguish keloids from hypertrophic scars, resulting in diagnostic accuracies of 1.0 and 0.75, respectively. Immunohistochemical Staining and Quantitative Reverse Transcription PCR revealed that the expression levels of tumour necrosis factor alpha induced protein 6 and insulin-like growth factor binding protein 6 were significantly lower in postburn keloids than in hypertrophic scars-</div></div><div><h3>Conclusions</h3><div>Tumour necrosis factor alpha induced protein 6 and insulin-like growth factor binding protein 6, exhibiting high diagnostic accuracy, provide valuable guidance for the differential diagnosis and treatment of postburn pathological scars-</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107255"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resveratrol promotes diabetic wound healing by inhibiting ferroptosis in vascular endothelial cells","authors":"Kui Xiao ,&nbsp;Sisi Wang ,&nbsp;Gang Li ,&nbsp;Wenxin Chen ,&nbsp;Bin Chen ,&nbsp;Xiaojian Li","doi":"10.1016/j.burns.2024.07.002","DOIUrl":"10.1016/j.burns.2024.07.002","url":null,"abstract":"<div><h3>Background</h3><div>Diabetic wounds are a common complication of diabetes, with alarming disability and mortality rates. Ferroptosis plays an essential role in the occurrence and development of diabetes mellitus and its complications, suggesting that mitigating ferroptosis can be used as a potential therapeutic strategy. Resveratrol (RSV) can promote the angiogenesis of diabetic wounds, but its molecular mechanism is unclear, and RSV has a role in regulating ferroptosis. Therefore, we speculated that RSV could promote the angiogenesis of diabetic wounds and accelerate wound healing by regulating ferroptosis.</div></div><div><h3>Methods</h3><div>In this study, we investigated the effects of RSV on human umbilical vein endothelial cells (HUVECs) treated with advanced glycation end-products (AGEs), focusing primarily on cell proliferation and markers associated with ferroptosis. The methods employed included the CCK-8 assay for cell proliferation, ROS determination, Fe²⁺ measurement, scratch and tube formation assays, and transcriptome analysis. To evaluate the effectiveness of RSV in promoting wound healing, we established a type 2 diabetes rat model and created a skin injury model. Wound healing rates were assessed, and tissue samples were analyzed using hematoxylin and eosin (H&amp;E) staining, immunohistochemistry, immunofluorescence, and Western blotting. Additionally, levels of glutathione (GSH) and malondialdehyde (MDA) were measured to evaluate oxidative stress and lipid peroxidation.</div></div><div><h3>Result</h3><div>Upon treatment of HUVECs with AGEs, we observed a decrease in cell viability and induction of ferroptosis. RSV can alleviate ferroptosis in AGEs-treated HUVECs. Further investigation through transcriptome analysis and Western blotting revealed that RSV alleviates ferroptosis in AGE-treated HUVECs by modulating the activity of nuclear factor erythroid 2-related factor 2 (Nrf2). In vivo experiments using a diabetic rat skin injury model confirmed that both RSV and Ferrostatin-1 (Fer-1) enhance wound healing and angiogenesis. This effect was associated with the regulation of ferroptosis marker proteins including GPX4, SLC7A11, and ACSL4. Additionally, in the diabetic rat groups treated with RSV and Fer-1, we noted increased expression of Nrf2, vascular endothelial growth factor (VEGF), and CD31 proteins compared to the diabetic rat control group.</div></div><div><h3>Conclusion</h3><div>In diabetic wounds, AGEs can lead to ferroptosis in HUVECs. RSV can inhibit AGE-induced ferroptosis in HUVECs, further promoting angiogenesis in diabetic wounds, and ultimately accelerating wound healing.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"50 9","pages":"Article 107198"},"PeriodicalIF":3.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}