Burns最新文献

{"title":"A call for comprehensive protocols and strategies: Identifying pediatric non-accidental burns","authors":"Julia Bartkova , Aksharaa Gurubalasubramaniyan Iyer , Rei Ogawa","doi":"10.1016/j.burns.2025.107419","DOIUrl":"10.1016/j.burns.2025.107419","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107419"},"PeriodicalIF":3.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative use of nasal stents to prevent adhesive nasal deformities following facial burns","authors":"Chao Lian, Xue-Lei Li, Xiao-Jun Liu, Xuan-Fen Zhang","doi":"10.1016/j.burns.2025.107505","DOIUrl":"10.1016/j.burns.2025.107505","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107505"},"PeriodicalIF":3.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nile tilapia skin in burn wound healing: A scoping review","authors":"Andrew Laurie Bustaman ,&nbsp;Peter Nugraha Soekmadji ,&nbsp;Ardo Sanjaya","doi":"10.1016/j.burns.2025.107503","DOIUrl":"10.1016/j.burns.2025.107503","url":null,"abstract":"<div><div>Burn wound management involves complex phases, with wound closure crucial for reducing mortality risk and achieving functional recovery. Though effective, traditional methods like skin grafting face limitations in extensive burns. Nile tilapia skin (NTS) has emerged as a promising alternative due to its high collagen content, biocompatibility, and moisture retention properties. A scoping review was conducted using EMBASE, Medline, and Cochrane Library databases. Inclusion criteria targeted studies using NTS in burn wound management across human and animal models. Outcomes analyzed included healing time, protein or gene expression changes, and cell proliferation. Articles were systematically screened and narratively synthesized. Of the 1035 articles retrieved, 13 met the inclusion criteria. Small-scale studies demonstrated that NTS accelerates wound healing, enhances re-epithelialization, and reduces pain compared to conventional treatments. Clinical trials highlighted faster recovery, decreased analgesic use, and fewer dressing changes in NTS-treated burns. However, these trials have marked limitations due to small study sample sizes, variability in application methods, and limited long-term outcome data. Mechanistically, NTS promotes cell migration, modulates inflammatory responses, and enhances angiogenesis. Its biocompatibility and antimicrobial properties further support its use. NTS represents a cost-effective, accessible alternative for burn wound management. However, standardizing protocols and conducting larger trials are essential for broader adoption. Addressing current treatment gaps can improve outcomes, particularly in low-resource environments. Further research is needed to standardize its use and optimize its therapeutic impact.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107503"},"PeriodicalIF":3.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating inter-and intra-rater reliability in the bronchoscopic grading of burn inhalation injury: The iBRONCH-BII study","authors":"Eleana T. Kumana ,&nbsp;Walton N. Charles ,&nbsp;Helena Milton-Jones ,&nbsp;Kaladerhan Agbontaen ,&nbsp;Sabri Soussi ,&nbsp;Ken Dunn ,&nbsp;Roger Davies ,&nbsp;Joanne Atkins ,&nbsp;Ceri Beynon ,&nbsp;Emmanuel Charbonney ,&nbsp;Dashiell Gantner ,&nbsp;Julian Giles ,&nbsp;Isabel Jones ,&nbsp;Niall Martin ,&nbsp;Oliver Pantet ,&nbsp;Odhran Shelley ,&nbsp;Alice Sisson ,&nbsp;Jagdish Sokhi ,&nbsp;Barclay T. Stewart ,&nbsp;Timothy Vorster ,&nbsp;Suveer Singh","doi":"10.1016/j.burns.2025.107502","DOIUrl":"10.1016/j.burns.2025.107502","url":null,"abstract":"<div><h3>Background</h3><div>The evidence that the severity of burn inhalation injury (BII) impacts clinical outcomes is inconsistent. This may be due to misclassification arising from the subjectivity in bronchoscopically grading BII using systems such as the Abbreviated Injury Score (AIS). This study aimed to evaluate inter- and intra-rater reliability in the grading of BII using the AIS.</div></div><div><h3>Methodology</h3><div>In a cohort study, specialist burns clinicians (n = 17) and novices (n = 10) graded sixteen BII bronchoscopic images using the AIS during an online meeting. Inter-rater reliability was evaluated using the Kappa statistic (k), with values &lt; 0.60 considered clinically inadequate. The grade rating process was repeated after seven days to evaluate intra-rater reliability. Evaluation of reliability in the grading of BII bronchoscopy reports was conducted as a sensitivity analysis.</div></div><div><h3>Results</h3><div>Amongst all raters, inter-rater reliability was low for grading images (k = 0.30, 95 % confidence interval (CI): 0.29–0.31). Intra-rater reliability was higher than inter-rater reliability, but was still low, with median image grade rate k = 0.45 (interquartile range [IQR]:0.24–0.53). Intensivists demonstrated the highest rater reliability.</div></div><div><h3>Conclusion</h3><div>Reliability in rating the grade of BII by bronchoscopic images was clinically inadequate. Strategies to improve the reliability of reporting the grade of BII are required.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107502"},"PeriodicalIF":3.2,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143903602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grading criteria on radionecrosis of skin (GCRNS) in adult patients: Insights from Delphi study and validation process","authors":"Meng-Yue Zhu ,&nbsp;Fei Yang ,&nbsp;Wei-Guo Xie ,&nbsp;Mao-Mao Xi ,&nbsp;Shu-Hua Liu ,&nbsp;Wei Zhang ,&nbsp;De-Yun Wang ,&nbsp;Wei-Dong Zhang ,&nbsp;Gang Yu ,&nbsp;Nan-Hong Jiang","doi":"10.1016/j.burns.2025.107473","DOIUrl":"10.1016/j.burns.2025.107473","url":null,"abstract":"<div><h3>Background</h3><div>Radionecrosis of skin (RNS) is the severe consequence of radiodermatitis (RD), which is a common complication experienced in up to 95 % of cancer patients after radiation therapy (RT). Recent publications revealed an absence of grading criteria for RNS and only crude forms for RD. However, treatments for RNS of different severity vary widely in terms of treatment difficulty and prognosis. This Delphi study aims to provide wound repair surgeons and oncologists a comprehensive guide for accurate RNS diagnosis, facilitating more effective surgical or operative interventions.</div></div><div><h3>Methods</h3><div>A three-round Delphi method was conducted between May and September 2022, involving 24 experts who specialize in the care or research of RNS. The process identified and weighted primary and secondary items to create a scale that reflects the severity of RNS. A receiver operating characteristic (ROC) curve was generated using the expert’s ratings (n = 15) as the benchmark to establish the grading criteria on RNS (GCRNS) with patient data (n = 64). To assess test-retest reliability, 32 physicians re-evaluate 64 patients’ files 2 weeks after their initial evaluation. The correlation between expert ratings and physician's re-evaluated grading was calculated to confirm concurrent validity.</div></div><div><h3>Results</h3><div>The final GCRNS consisted of 18 secondary items categorized under 6 primary items, including ulcer duration, peripheral skin, ulcer area, underlying disease, ulcer depth, and severe complications. Severity classification thresholds were proposed by ROC curve, defining severity levels as mild, moderate, and severe. Six primary items were positively correlated the severity of RNS with affirming its concurrent validity (r = 0.751, p &lt; 0.001). Good internal consistency (α=0.831) and test-retest reliability (r = 0.969, p &lt; 0.001) were demonstrated.</div></div><div><h3>Conclusions</h3><div>GCRNS is an expert-driven and comprehensive approach to RNS assessment for further wound repair. By improving diagnostic accuracy, particularly among junior surgeons, GCRNS with strong concurrent validity and reliability, enhances clinical decision-making and supports more effective treatment planning.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107473"},"PeriodicalIF":3.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Naringenin loaded nanomicelles effect on second-degree burn in Balb/c mice: A promising formulation for wound healing","authors":"Fatemeh Monzavipourbana ,&nbsp;Mahmoud Reza Jaafari ,&nbsp;Shima Afrasiabi ,&nbsp;Partow Mirzaee Saffari ,&nbsp;Javad Zarqi ,&nbsp;Gholamreza Hassanzadeh ,&nbsp;Seyyedeh Elaheh Mousavi ,&nbsp;Seyed Mahdi Rezayat ,&nbsp;Alireza Partoazar","doi":"10.1016/j.burns.2025.107494","DOIUrl":"10.1016/j.burns.2025.107494","url":null,"abstract":"<div><div>Burns can cause long-term complications and require immediate and effective treatment in patients. The therapeutic potential of naringenin (NG) is hampered by its hydrophobic nature. To improve the bioavailability and efficacy of NG in experimental burn wounds in mice, NG-loaded nanomicelles (NGMs) were prepared using the thin-film hydration method. The characterization of the formulation in different concentrations (0.3 %, 0.6 %, and 1.25 %) was carried out using HPLC, DLS, and TEM techniques. A second-degree burn was inflicted on the back of the mice for evaluation of NGM efficacy. The NGM formulation was evaluated topically on the treated mice for wound recovery, improvement of histological and immunohistochemical parameters, and <em>in vitro</em> antibacterial activity. The effect of NGMs on wound healing was evaluated by hematoxylin and eosin (H&amp;E) and Masson’s trichrome staining (MT), and expression of transforming growth factor-β (TGF-β) and nuclear factor-κB (NFκ-B) using immunohistochemistry (IHC). The characterization tests revealed nanosized micelles with dimensions around 7 nm and a high entrapment efficiency percentage of NG which had sustained release behavior. Wound healing was significantly faster in mice treated with NGMs (0.3 %) compared to other concentrations, silver sulfadiazine (SSD), and an untreated group. IHC analysis of mice receiving NGMs (0.3 %) showed a significant reduction in NFκ-B, while TGF-β1 was increased. In addition, NGMs exhibited significant bactericidal activity against <em>Staphylococcus aureus</em> and <em>Pseudomonas aeruginosa in vitro</em>. These findings show that NGMs accelerate the wound-healing process and lead to regeneration of the epidermis without the need for additional medication.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107494"},"PeriodicalIF":3.2,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding drivers of fire risk with people experiencing homelessness","authors":"Caitlin M. Orton ,&nbsp;Mark Gannon ,&nbsp;Aldina Mešić ,&nbsp;Mona Chambers ,&nbsp;Leslie Enzian ,&nbsp;Tam N. Pham ,&nbsp;Barclay T. Stewart","doi":"10.1016/j.burns.2025.107482","DOIUrl":"10.1016/j.burns.2025.107482","url":null,"abstract":"<div><div>Fire hazards affecting people who are unhoused span natural and built environments, social circumstances, and human behavior. Identifying key drivers of fire risk and burn injury can inform injury prevention and control initiatives. We conducted 12 key informant interviews with burn patients who were unhoused. Deductive and inductive strategies were used to code transcripts. Corcoran’s conceptual model of fire risk was applied in order to group factors into environmental, social, and behavioral categories. The most frequently used fire sources were propane, hand sanitizer, and other alcohol-based liquids. Unsafely contained open flames and improper propane tank storage were frequently identified hazards. Participants described the interplay of environmental, social, and behavioral factors that need to be accounted for when addressing fire hazards. For example, the use of propane heaters inside tents is common because it is effective in warming living spaces and limits the risk of having equipment stolen. This project identified specific environmental risks, socioeconomic risks, and their interplay with identified fire hazards as foundational to injury control for people experiencing homelessness. Injury prevention strategies need to be evaluated within the complex environments of homelessness (e.g., exposure to severe weather, unsafe and potentially violent living conditions, substance use, social marginalization, and limited access to injury prevention media).</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107482"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing new education standards in burns – A scoping review","authors":"Agnieszka Surowiecka ,&nbsp;Zofia Górecka ,&nbsp;Magdalena Kozicka ,&nbsp;Magdalena Staśkiewicz ,&nbsp;Sylwia Panek ,&nbsp;Marek Majewski ,&nbsp;Grzegorz Wilhelm ,&nbsp;Marcelina Podleśna ,&nbsp;Jerzy Strużyna ,&nbsp;Kamil Torres","doi":"10.1016/j.burns.2025.107493","DOIUrl":"10.1016/j.burns.2025.107493","url":null,"abstract":"<div><h3>Introduction</h3><div>This scoping review aimed to provide an overview of prospective new burn education requirements.</div></div><div><h3>Data source</h3><div>Three independent researchers (AS, ZG, MK) screened the articles in medical databases (PubMed, Scopus, Google Scholar).</div></div><div><h3>Study inclusion and exclusion criteria</h3><div>The inclusion filters were “education + burn” or “simulation + burns” and “Entrustable Professional Activity + burns”. Titles, abstracts and full texts in English were filtered to choose original articles and reviews describing novel methods in education in burns.</div></div><div><h3>Results</h3><div>The search strategy identified 2214 records. 24 studies were enrolled into the study.</div></div><div><h3>Conclusions</h3><div>Medical simulation in burns and Entrustable Professional Activities are promising tools in burn education. Skill-specific unified Entrustable Professional Activities should be established to improve burn team performance.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107493"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of concern about \"The use of silk dressings in the treatment of skin injuries: a systematic review\"","authors":"Linda L. Benskin","doi":"10.1016/j.burns.2025.107481","DOIUrl":"10.1016/j.burns.2025.107481","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107481"},"PeriodicalIF":3.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enablers and barriers to participation in physical activity programs while hospitalized after burn injury: The patient perspective","authors":"Anita Plaza ,&nbsp;Brooke Mulliss ,&nbsp;Julie Adsett ,&nbsp;Andrea McKittrick ,&nbsp;Allison Hill ,&nbsp;Prue McRae ,&nbsp;Alison Mudge","doi":"10.1016/j.burns.2025.107479","DOIUrl":"10.1016/j.burns.2025.107479","url":null,"abstract":"<div><h3>Background</h3><div>Physical activity is an essential component of burn rehabilitation; however, the patient experience of factors that contribute to physical activity participation while hospitalized after burn injury has not yet been described. This study aimed to identify enablers and barriers to participation in physical activity while hospitalized after burn injury from the patient perspective.</div></div><div><h3>Methods</h3><div>A qualitative descriptive study design was undertaken. Purposive sampling was used to recruit adults with burn injuries admitted to the burn center between February and July 2022. Semi-structured interviews were conducted by a research assistant not involved in clinical care, audio-recorded and transcribed verbatim. All de-identified transcripts were analyzed using an inductive thematic approach and organized into major themes.</div></div><div><h3>Results</h3><div>Twenty participants (18 males) with average age of 47 years and mean burn size of 13.8 % total body surface area were included. Factors which influenced patients’ ability to participate in physical activity were summarized into six major themes: 1) Burn injury factors; 2) Patient factors; 3) Staff support; 4) Family support; 5) Peer support; 6) Environmental factors. Pain, fear of causing further pain or harm and beliefs regarding the need for rest to achieve wound healing were identified as major barriers to physical activity performance. Family support and supportive care from staff were highly valued enablers.</div></div><div><h3>Conclusion</h3><div>This is the first study to describe the patient experience of physical activity participation while hospitalized after a burn injury. Understanding the patient perspective is integral to developing appropriate multi-component interventions to promote increased physical activity early after burn injury.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107479"},"PeriodicalIF":3.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}