Burns最新文献_第2页

The soldier in white: A guide to burn resuscitation? 白衣士兵：烧伤复苏指南？

IF 3.2 3区医学

Burns Pub Date : 2025-02-01 DOI: 10.1016/j.burns.2024.107342

T.S. Burge

引用次数: 0

DSM-5 acute stress disorder in hospitalized burn patients: The impact and interplay of pre- and peri-trauma psychological risk factors 住院烧伤患者的 DSM-5 急性应激障碍：创伤前后心理风险因素的影响和相互作用。

IF 3.2 3区医学

Burns Pub Date : 2025-02-01 DOI: 10.1016/j.burns.2024.107346

Yi-Jen Su

{"title":"DSM-5 acute stress disorder in hospitalized burn patients: The impact and interplay of pre- and peri-trauma psychological risk factors","authors":"Yi-Jen Su","doi":"10.1016/j.burns.2024.107346","DOIUrl":"10.1016/j.burns.2024.107346","url":null,"abstract":"<div><h3>Objective</h3><div>Burn injuries can be traumatic and lead to psychological sequelae, particularly acute stress disorder (ASD). Information regarding the prevalence and risk factors of ASD following <em>DSM-5</em> criteria is relatively limited among survivors of burn and other traumas. This study aimed to investigate the prevalence of probable ASD post-burn according to <em>DSM-5</em> criteria and explore the impact and interplay of pre- and peri-trauma psychological risk factors on <em>DSM-5</em> ASD symptomatology.</div></div><div><h3>Methods</h3><div>Between February 2017 and November 2020, 118 patients admitted to the largest burn center in Taiwan were enrolled, with 100 completing assessments within 30 days of injury during acute hospitalization. Most participants were men (73 %), with a mean age of 41.9<span><math><mo>±</mo></math></span>12.5 years. The average percentage of total body surface area (TBSA) burned was 15.1<span><math><mo>±</mo></math></span>11.5 %.</div></div><div><h3>Results</h3><div>Around 9 % of the hospitalized burn patients had probable <em>DSM-5</em> ASD. The most common ASD symptoms were intrusive memories, distress triggered by trauma reminders, and distressing dreams. Pre- and peri-trauma psychological risk factors uniquely accounted for 42.4 % of the variance in <em>DSM-5</em> ASD symptomatology post-burn after adjusting for covariates. Both peritraumatic emotions and peritraumatic dissociation emerged as strong predictors with medium-to-large effect sizes (semi-partial <em>r</em><sup><em>2</em></sup> =.13 and .09). Notably, prior depression severity significantly moderated the associations between peri-trauma psychological risk factors and ASD symptoms post-burn (incremental <em>R</em><sup><em>2</em></sup> = 5.6–8.8 %).</div></div><div><h3>Conclusion</h3><div>The findings underscore the interplay of pre- and peri-trauma psychological processes in susceptibility to ASD symptomatology post-burn.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 1","pages":"Article 107346"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cum Grano Salis - Irrigation of chemical burns? 化学烧伤的灌溉？

IF 3.2 3区医学

Burns Pub Date : 2025-02-01 DOI: 10.1016/j.burns.2024.107340

Jasmine Crane , Sirous Golchinheydari, Fatma Shariff, Timothy Burge

引用次数: 0

Construction of an instrument to evaluate the quality of hospital care provided in burns units in Brazil: A Delphi study 构建一种评估巴西烧伤医院护理质量的仪器：德尔菲研究。

IF 3.2 3区医学

Burns Pub Date : 2025-02-01 DOI: 10.1016/j.burns.2024.107316

Denise R. Rabelo Suzuki , Levy Aniceto Santana , Juliana Elvira H. Guerra Ávila , Fábio Ferreira Amorim , Vinicius Maldaner

{"title":"Construction of an instrument to evaluate the quality of hospital care provided in burns units in Brazil: A Delphi study","authors":"Denise R. Rabelo Suzuki , Levy Aniceto Santana , Juliana Elvira H. Guerra Ávila , Fábio Ferreira Amorim , Vinicius Maldaner","doi":"10.1016/j.burns.2024.107316","DOIUrl":"10.1016/j.burns.2024.107316","url":null,"abstract":"<div><h3>Background</h3><div>Providing excellent care to patients with acute burns can result in lower mortality and disability in the long-term. There are no specific instruments to evaluate the quality of care provided at this stage of treatment. This study aims to create an instrument to evaluate the quality of hospital care provided to patients with acute burns in Brazil.</div></div><div><h3>Methods</h3><div>The Delphi technique was used to obtain a consensus among experts on which constructs should be incorporated into the instrument. The sample comprised professionals experienced in treating burn victims and subscribed to the Brazilian Society of Burns mailing lists. Each statement was judged on a 5-point Likert scale. A percentage of agreement equal to or higher than 75 % was defined as a consensus. Data were analyzed using content analysis and descriptive summary statistics.</div></div><div><h3>Results</h3><div>The first round obtained responses from 34 experts, with a mean of 11.98 (SD 9.29) years of experience. After three rounds, 106 statements reached consensus for inclusion and served as the basis for the instrument.</div></div><div><h3>Conclusion</h3><div>Our study identified key terms, and consensus was reached on 106 statements; a need to define clear outcome evaluation methods was observed.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 1","pages":"Article 107316"},"PeriodicalIF":3.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hot water bottles – Could instructions be clearer for burns prevention? 热水瓶——预防烧伤的说明能更清楚吗？

IF 3.2 3区医学

Burns Pub Date : 2025-02-01 DOI: 10.1016/j.burns.2024.107333

Isabella Birkby (IB), Karl Walsh (KW)

引用次数: 0

A systematic review of advances in the use of spectral imaging in burn depth assessment

IF 3.2 3区医学

Burns Pub Date : 2025-01-30 DOI: 10.1016/j.burns.2025.107401

Poh Tan , Krishna Ravulapalli , Christopher J. Lewis

{"title":"A systematic review of advances in the use of spectral imaging in burn depth assessment","authors":"Poh Tan , Krishna Ravulapalli , Christopher J. Lewis","doi":"10.1016/j.burns.2025.107401","DOIUrl":"10.1016/j.burns.2025.107401","url":null,"abstract":"<div><h3>Background</h3><div>Accurate burn depth assessment is critical for determining appropriate treatment and optimizing patient outcomes. Conventional methods, such as clinical assessment and laser Doppler imaging, have limitations in terms of accuracy and timeliness. Spectral imaging, including multispectral imaging and hyperspectral imaging, has emerged as a promising non-invasive modality to improve burn depth evaluation. This systematic review aims to evaluate the advances in spectral imaging technologies for burn depth assessment, with a focus on diagnostic accuracy, the role of machine learning integration, and the quality of current evidence.</div></div><div><h3>Methods</h3><div>A comprehensive literature search was conducted in March 2024 using PubMed, Scottish Network, EMBASE, and Cochrane Library databases. Studies that evaluated spectral imaging for burn depth assessment and compared it to standard methods such as laser Doppler imaging, clinical assessment, or histological analysis were included. The quality of the included studies was assessed using the QUADAS tool.</div></div><div><h3>Results</h3><div>Seven studies from 1988 to 2023 met the inclusion criteria, evaluating a total of 167 patients with 269 burn sites. The pooled analysis revealed a combined sensitivity of 86 % (95 % CI [0.80; 0.90]) and specificity of 84 % (95 % CI [0.70; 0.93]. However, there was a large range of sensitivity identified from 61 % to 97.2 % and specificity from 45 % to 100 %. Notably, the integration of machine learning, particularly convolutional neural networks and support vector machines, improved classification accuracy, with some models achieving over 95 % sensitivity and specificity. Despite these promising results, significant variability in methodologies and a lack of standardized ground truthing were identified.</div></div><div><h3>Conclusion</h3><div>Spectral imaging, especially when combined with machine learning, shows strong potential as an effective tool for burn depth assessment, offering high diagnostic accuracy and reproducibility. Further research is needed to standardize protocols and validate these technologies across diverse patient populations, paving the way for clinical adoption and improved patient care.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 3","pages":"Article 107401"},"PeriodicalIF":3.2,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143377847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to “Survey about target temperature and thermal management in intensive care for severe thermal trauma in burn centres of Germany, Austria and Switzerland” [Burns 51 (2025) 107308]

IF 3.2 3区医学

Burns Pub Date : 2025-01-22 DOI: 10.1016/j.burns.2025.107388

Stefan Trojan , Friedemann Stein , Rolf Lefering , Thorsten Annecke , Frank Wappler , Ulrich Limper

引用次数: 0

Corrigendum to “Examination of the effects of kefir on healing factors in a mice burn model infected with E. coli, S. aureus and P. aeruginosa using qRT-PCR” [Burns 49 (2023) 425–431]

IF 3.2 3区医学

Burns Pub Date : 2025-01-22 DOI: 10.1016/j.burns.2024.107370

Songul Cetik Yildiz , Cemil Demir , Adnan Ayhanci

引用次数: 0

The effect of nitrile gloves on temperature perception during hot water immersion

IF 3.2 3区医学

Burns Pub Date : 2025-01-21 DOI: 10.1016/j.burns.2025.107392

David Cussons , Aude Perusseau-Lambert , Quentin Frew , David Barnes , Simon Myers , Peter Dziewulski

{"title":"The effect of nitrile gloves on temperature perception during hot water immersion","authors":"David Cussons , Aude Perusseau-Lambert , Quentin Frew , David Barnes , Simon Myers , Peter Dziewulski","doi":"10.1016/j.burns.2025.107392","DOIUrl":"10.1016/j.burns.2025.107392","url":null,"abstract":"<div><h3>Introduction</h3><div>Scalds account for 40 % of burn injuries in developed countries, with a subset occurring during caregiving activities, particularly when gloves are worn. Gloves, a standard precaution against infection and body fluid exposure, may impair sensory feedback critical for detecting temperature changes, potentially increasing the risk of burns during personal care tasks.</div></div><div><h3>Methods</h3><div>This study investigated the impact of glove use on heat perception. Twelve healthy participants (6 male, 6 female) immersed their index fingers in water baths set at 40°C, 45°C, 50°C, 55°C, and 60°C. Heat perception thresholds were assessed under three conditions: no gloves, single gloves, and double gloves. Participants withdrew their fingers upon feeling discomfort, and the withdrawal temperatures were recorded.</div></div><div><h3>Results</h3><div>Our trial showed that gloves significantly delayed heat discomfort detection, with the longest delays observed at 50°C and 55°C when double gloves were worn. Wearing a single glove raised the discomfort threshold by approximately 5°C, while double gloves increased it by 10°C. This logarithmic relationship between temperature and perception delay indicates a substantial sensory alteration, especially at higher temperatures.</div></div><div><h3>Conclusion</h3><div>The findings underscore the heightened risk of scald injuries in vulnerable individuals due to delayed heat detection caused by gloves. Awareness of altered temperature thresholds during glove use is essential to prevent burns during caregiving tasks, particularly in activities requiring precise temperature assessment, such as bathing or showering. Enhanced education and preventive measures are crucial for ensuring safety in these contexts.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 3","pages":"Article 107392"},"PeriodicalIF":3.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multi-omics analysis to explore the molecular mechanisms related to keloid

IF 3.2 3区医学

Burns Pub Date : 2025-01-21 DOI: 10.1016/j.burns.2025.107396

Hailin Xu , Keai Li , Xiaofeng Liang , Zhiyong Wang , Bin Yang

{"title":"Multi-omics analysis to explore the molecular mechanisms related to keloid","authors":"Hailin Xu , Keai Li , Xiaofeng Liang , Zhiyong Wang , Bin Yang","doi":"10.1016/j.burns.2025.107396","DOIUrl":"10.1016/j.burns.2025.107396","url":null,"abstract":"<div><h3>Background</h3><div>Keloid is a benign skin tumor that result from abnormal wound healing and excessive collagen deposition. The pathogenesis is believed to be linked to genetic predisposition and immune imbalance, although the precise mechanisms remain poorly understood. Current therapeutic approaches may not consistently yield satisfactory outcomes and are often accompanied by potential side effects and risks. The high recurrence rate and refractory nature of keloid nodules present significant challenges and uncertainties in their management. Given the lack of effective treatment strategies, it is essential to identify key molecular pathways and potential therapeutic targets for keloid.</div></div><div><h3>Objective</h3><div>This study aimed to identify the potential pathogenic mechanisms, hub genes, and immune cell involvement in keloid formation, with the goal of providing novel insights for targeted therapies.</div></div><div><h3>Methods</h3><div>We utilized a combination of bulk RNA sequencing to analyze gene expression profiles in keloid tissues. Differentially expressed genes (DEGs) were identified and subjected to pathway enrichment analysis to reveal key biological processes involved in keloid pathogenesis. Mendelian randomization was performed to investigate the causal relationship between genetic factors and keloid formation, identifying potential hub genes. Immune infiltration analysis was conducted to determine the role of specific immune cells in keloid development. Subsequently, Gene Set Enrichment Analysis (GSEA) and Gene Set Variation Analysis (GSVA) were performed to investigate the functional pathways associated with the hub genes. Network analysis was employed to identify transcription factors, miRNAs, and potential drugs in the Connectivity Map associated with the hub genes. Single-cell RNA sequencing was also used to identify cell-specific expression patterns of these genes.</div></div><div><h3>Results</h3><div>Pathway enrichment analysis highlighted the association of keloid pathogenesis with cell proliferation and division, providing insights into the molecular processes involved. Mendelian randomization revealed that DUSP1 acts as an inhibitor of keloid formation, while HOXA5 promotes keloid pathogenesis. Immune infiltration analysis suggested that mast cells and macrophages play critical roles in the disease's progression. Based on hub gene analysis, the IL17 signaling pathway emerged as a key pathway implicated in keloid development. Further drug prediction models identified 9-methyl-5H-6-thia-4, 5-diaza-chrysene-6, 6-dioxide, zebularine, temozolomide and valproic acid targeting these hub genes.</div></div><div><h3>Conclusion</h3><div>DUSP1 and HOXA5 are hub genes in keloid pathogenesis, with DUSP1 acting as an inhibitor and HOXA5 as a promoter of disease progression. Targeting the regulatory networks associated with these genes could provide novel therapeutic strategies. Mast cells and macrophages are identif","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 3","pages":"Article 107396"},"PeriodicalIF":3.2,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143059916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0