Burns最新文献

{"title":"Establishing new education standards in burns – A scoping review","authors":"Agnieszka Surowiecka ,&nbsp;Zofia Górecka ,&nbsp;Magdalena Kozicka ,&nbsp;Magdalena Staśkiewicz ,&nbsp;Sylwia Panek ,&nbsp;Marek Majewski ,&nbsp;Grzegorz Wilhelm ,&nbsp;Marcelina Podleśna ,&nbsp;Jerzy Strużyna ,&nbsp;Kamil Torres","doi":"10.1016/j.burns.2025.107493","DOIUrl":"10.1016/j.burns.2025.107493","url":null,"abstract":"<div><h3>Introduction</h3><div>This scoping review aimed to provide an overview of prospective new burn education requirements.</div></div><div><h3>Data source</h3><div>Three independent researchers (AS, ZG, MK) screened the articles in medical databases (PubMed, Scopus, Google Scholar).</div></div><div><h3>Study inclusion and exclusion criteria</h3><div>The inclusion filters were “education + burn” or “simulation + burns” and “Entrustable Professional Activity + burns”. Titles, abstracts and full texts in English were filtered to choose original articles and reviews describing novel methods in education in burns.</div></div><div><h3>Results</h3><div>The search strategy identified 2214 records. 24 studies were enrolled into the study.</div></div><div><h3>Conclusions</h3><div>Medical simulation in burns and Entrustable Professional Activities are promising tools in burn education. Skill-specific unified Entrustable Professional Activities should be established to improve burn team performance.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107493"},"PeriodicalIF":3.2,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expression of concern about \"The use of silk dressings in the treatment of skin injuries: a systematic review\"","authors":"Linda L. Benskin","doi":"10.1016/j.burns.2025.107481","DOIUrl":"10.1016/j.burns.2025.107481","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107481"},"PeriodicalIF":3.2,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enablers and barriers to participation in physical activity programs while hospitalized after burn injury: The patient perspective","authors":"Anita Plaza ,&nbsp;Brooke Mulliss ,&nbsp;Julie Adsett ,&nbsp;Andrea McKittrick ,&nbsp;Allison Hill ,&nbsp;Prue McRae ,&nbsp;Alison Mudge","doi":"10.1016/j.burns.2025.107479","DOIUrl":"10.1016/j.burns.2025.107479","url":null,"abstract":"<div><h3>Background</h3><div>Physical activity is an essential component of burn rehabilitation; however, the patient experience of factors that contribute to physical activity participation while hospitalized after burn injury has not yet been described. This study aimed to identify enablers and barriers to participation in physical activity while hospitalized after burn injury from the patient perspective.</div></div><div><h3>Methods</h3><div>A qualitative descriptive study design was undertaken. Purposive sampling was used to recruit adults with burn injuries admitted to the burn center between February and July 2022. Semi-structured interviews were conducted by a research assistant not involved in clinical care, audio-recorded and transcribed verbatim. All de-identified transcripts were analyzed using an inductive thematic approach and organized into major themes.</div></div><div><h3>Results</h3><div>Twenty participants (18 males) with average age of 47 years and mean burn size of 13.8 % total body surface area were included. Factors which influenced patients’ ability to participate in physical activity were summarized into six major themes: 1) Burn injury factors; 2) Patient factors; 3) Staff support; 4) Family support; 5) Peer support; 6) Environmental factors. Pain, fear of causing further pain or harm and beliefs regarding the need for rest to achieve wound healing were identified as major barriers to physical activity performance. Family support and supportive care from staff were highly valued enablers.</div></div><div><h3>Conclusion</h3><div>This is the first study to describe the patient experience of physical activity participation while hospitalized after a burn injury. Understanding the patient perspective is integral to developing appropriate multi-component interventions to promote increased physical activity early after burn injury.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107479"},"PeriodicalIF":3.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early ambulation following lower limb burn and surgery is associated with improved long-term functional outcome and reduced hospital length of stay: A longitudinal cohort study","authors":"Claudia J. Tatlow ,&nbsp;Dana A. Hince ,&nbsp;Chelsea K. Evans ,&nbsp;Piers Truter ,&nbsp;Pip C. Pienaar ,&nbsp;Fiona M. Wood ,&nbsp;Max Bulsara ,&nbsp;Aaron Berghuber ,&nbsp;Paul M. Gittings ,&nbsp;Dale W. Edgar","doi":"10.1016/j.burns.2025.107474","DOIUrl":"10.1016/j.burns.2025.107474","url":null,"abstract":"<div><h3>Introduction</h3><div>Ambulating early after lower limb burn surgery has been associated with a multitude of in-hospital and short-term benefits. However, long-term functional recovery following lower limb burns is poorly understood, especially if grafting surgery is required.</div></div><div><h3>Objectives</h3><div>This study aimed to explore the association between early ambulation following lower limb burn injury and surgery, long-term lower limb functional recovery and secondly, hospital length of stay (LOS).</div></div><div><h3>Methods</h3><div>This retrospective longitudinal cohort study reported data from 1718 adult patients treated by a tertiary hospital burn center in Western Australia between February 2011 and December 2019 following a lower limb burn injury.</div></div><div><h3>Results</h3><div>Comparable lower limb function outcomes were found at six weeks after injury regardless of burn severity or timing of ambulation. Early ambulation pathways were associated with the likelihood of achieving a better long-term functional recovery over the first year after burn. A positive association was also confirmed between early ambulation and hospital LOS. After adjustment, patients who ambulated early after burn and surgery had a LOS of 1.76 days less than patients who ambulated early after burn but late after surgery (IRR 1.22, 95 % CI:1.13–1.3, p &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>Early ambulation before the third day after lower limb burn injury and surgery was associated with improved long-term functional outcome trajectory to one year and reduced hospital LOS by of 1.76 days when patients ambulated early after surgery. Future investigations with larger, targeted samples of complex patients are warranted to explore the influence of early ambulation on the outcomes of multi-morbidity subgroups.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107474"},"PeriodicalIF":3.2,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143829046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxic shock syndrome (TSS) and burns: A structured triage pathway","authors":"Kin Seng Tong,&nbsp;Clare Thomas,&nbsp;Barbara Minto,&nbsp;Lisa Hyde,&nbsp;Yvonne Wilson,&nbsp;Federica D’Asta","doi":"10.1016/j.burns.2025.107480","DOIUrl":"10.1016/j.burns.2025.107480","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107480"},"PeriodicalIF":3.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143834131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of the potential role of PANoptosis-related genes in burns via bioinformatic analyses and experimental validation","authors":"Jiacong Chen ,&nbsp;Qin Zhou ,&nbsp;Yang Cao ,&nbsp;Xuexian Tang ,&nbsp;Yan Zhang ,&nbsp;Lin Wang ,&nbsp;Junxi Li ,&nbsp;Bing Liang","doi":"10.1016/j.burns.2025.107477","DOIUrl":"10.1016/j.burns.2025.107477","url":null,"abstract":"<div><h3>Background</h3><div>The treatment of burns is highly challenging due to their complex pathophysiological mechanisms. PANoptosis, as an important form of cell death, is suggested to play a crucial role in the inflammatory response and tissue damage following burns. However, the role of PANoptosis-related biomarkers in the pathophysiological processes of burns remains unclear. In this study, we aim to identify PANoptosis-related signature genes and validate them as biomarkers in burns</div></div><div><h3>Methods</h3><div>Burn-related datasets were obtained from the Gene Expression Omnibus（GEO） database. GSE37069 was used for bioinformatic analysis and machine learning, while GSE19743 was used specifically for external validation. A set of PANoptosis-associated genes was obtained from the GeneCards database. Three machine learning models (LASSO, RF, and SVM-RFE) and WGCNA were utilized to screen for signature genes. The diagnostic efficacy of the identified genes was assessed through receiver operating characteristic (ROC) curves. Gene Set Enrichment Analysis (GSEA) was performed to identify pathways associated with the signature genes, while single-sample gene set enrichment analysis (ssGSEA) was employed to investigate the immune landscape. Finally, Western blotting and RT-qPCR were employed to validate the signature genes.</div></div><div><h3>Results</h3><div>BCL-2, CCAR1, CERK, TRIAP1, S100A8, and SNHG1 were identified as signature genes. The biological processes involving these genes mainly include endocytosis, apoptosis, and ECM receptor interaction. Immune infiltration analysis revealed that neutrophils, eosinophils, M0 macrophages, and monocytes are significantly elevated in burn samples. Additionally, these signature genes showed significant correlations with multiple immune cell types. Finally, Western blotting and RT-qPCR analysis revealed that the expression levels of BCL2, CCAR1, CERK, and TRIAP1 were significantly down-regulated in the burn groups compared to the normal groups, with the exception of S100A8.</div></div><div><h3>Conclusion</h3><div>Our study has identified BCL-2, CCAR1, CERK, and TRIAP1 as reliable potential biomarkers for burn injuries. These genes play crucial roles in immune response, wound healing, and anti-apoptotic mechanisms, which are key pathological processes involved in the progression of burn injuries. Specifically, BCL-2, CCAR1, CERK, and TRIAP1 have been shown to significantly impact the regulation of inflammation, the efficiency of wound repair, and the prevention of cell apoptosis during burn injury.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107477"},"PeriodicalIF":3.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual reality in pediatric burn care: Optimizing pain assessment strategies","authors":"Seyed Javad Hosseini,&nbsp;Seyed Reza Hosseini,&nbsp;Mahbobeh Firooz","doi":"10.1016/j.burns.2025.107476","DOIUrl":"10.1016/j.burns.2025.107476","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107476"},"PeriodicalIF":3.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143899680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The health impact of South Africa’s loadshedding","authors":"Tshepang A. Motsepe","doi":"10.1016/j.burns.2025.107478","DOIUrl":"10.1016/j.burns.2025.107478","url":null,"abstract":"","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107478"},"PeriodicalIF":3.2,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and reliability study of 12 Item Pruritus Severity Scale for Turkish patients with burns","authors":"Handan Aktas ,&nbsp;Zahide Tuncbilek","doi":"10.1016/j.burns.2025.107475","DOIUrl":"10.1016/j.burns.2025.107475","url":null,"abstract":"<div><h3>Aim</h3><div>Itching sensation after burn injury has biological, psychological, and social effects on the patient. Objective assessment of itching in burn patients is a problem and one of the most important obstacles is the lack of adequate assessment criteria. This study was conducted to examine the validity and reliability of the “12 Item Pruritus Severity Scale” developed to assess the severity of itching in individuals with burn trauma for the Turkish population.</div></div><div><h3>Method</h3><div>The study data were collected between January and June 2019 at the burn outpatient clinic in the Burn Center of a city hospital. The study included 120 patients in the age group of 18–65 years who had suffered a burn injury since September 2018, whose pruritus severity was 1 or higher according to VAS, and who were followed up in the burn outpatient clinic after being discharged at least 15 days after the burn injury. The data of the study were collected with a “12Item Pruritus Severity Scale”. Language validity, content validity, convergent validity and internal consistency analysis were used for the validity and reliability study of the scale.</div></div><div><h3>Results</h3><div>The internal consistency reliability coefficient of the scale was found to be 0.79. The 7th item in the scale was not found to be correlated with the scale total score (p &gt; 0.05), while the other 11 items were positively correlated with the scale total score (p &lt; 0.0001). The concurrent validity of the scale was evaluated with VAS and the validity coefficient was found to be high (p &lt; 0.0001).</div></div><div><h3>Conclusion</h3><div>Based on the data obtained from the study, the “12 Item Pruritus Severity Scale” adapted for the Turkish population was found to be valid and reliable to be applied to individuals with burn trauma.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107475"},"PeriodicalIF":3.2,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143879251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of silk sheets derived from germ-free silkworms on wound healing of full-thickness epithelial defects","authors":"Ryo Tosaka ,&nbsp;Takanori Eguchi ,&nbsp;Tadatoshi Ishizuka ,&nbsp;Koji Kawaguchi ,&nbsp;Takayuki Nagashima ,&nbsp;Ryoko Nakayama ,&nbsp;Yoshiki Hamada","doi":"10.1016/j.burns.2025.107470","DOIUrl":"10.1016/j.burns.2025.107470","url":null,"abstract":"<div><div>Collagen is widely used as a scaffold for full-thickness epithelial defects but has poor biostability and often induces hypertrophic scarring. Silk, especially silk derived from germ-free silkworms (SGFS), has high biocompatibility and controllable durability. Therefore, SGFS is possibly for medicine. Herein, we evaluated the effects of SGFS as a scaffold in the wound healing of full-thickness epithelial defects. Epithelial defects were made in the dorsal skin of C57BL/6 J mice, and an SGFS or a collagen sheet was applied to each defect and compared. On days 1, 3, 7, and 14 after surgery, re-epithelialization, inflammatory responses, and granulation tissue formation of each wound were assessed and compared between the groups. Re-epithelialization was observed in the SGFS group on day 3 but no re-epithelialization occurred in the collagen group. Histopathological examination showed less granulation tissue formation in the SGFS group than in the collagen group. IL-6 expression was significantly higher in the SGFS group than in the collagen group on day 1. TGF-β1 expression in the SGFS group was significantly lower than that in the collagen sheet group on days 7 and 14. Based on these results, SGFS promoted re-epithelialization and reduced hypertrophic scarring in the wound healing process compared with collagen.</div></div>","PeriodicalId":50717,"journal":{"name":"Burns","volume":"51 5","pages":"Article 107470"},"PeriodicalIF":3.2,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143906647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}