Clinical ImagingPub Date : 2025-09-26DOI: 10.1016/j.clinimag.2025.110627
Stephanie El Omeiri , Karen I. Ramirez-Suarez , Joseph Stern , Hansel J. Otero , Yoav Dori , David M. Biko , Jordan B. Rapp , Fernando Escobar , Aaron Dewitt , Ganesh Krishnamurthy , Abhay Srinivasan , Christopher L. Smith
{"title":"Imaging of central lymphatics in children with Both Trisomy 21 and congenital heart disease","authors":"Stephanie El Omeiri , Karen I. Ramirez-Suarez , Joseph Stern , Hansel J. Otero , Yoav Dori , David M. Biko , Jordan B. Rapp , Fernando Escobar , Aaron Dewitt , Ganesh Krishnamurthy , Abhay Srinivasan , Christopher L. Smith","doi":"10.1016/j.clinimag.2025.110627","DOIUrl":"10.1016/j.clinimag.2025.110627","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the lymphatic imaging findings in patients with both Trisomy 21 and congenital heart disease and to depict the most common central lymphatic abnormalities in these patients.</div></div><div><h3>Materials and methods</h3><div>We conducted a single-center retrospective review of patients with a confirmed history of Trisomy 21 and congenital heart disease who presented for lymphatic imaging over a 7-year period. Clinical history and outcomes were extracted from the medical records. Lymphatic distribution and flow were evaluated by two pediatric radiologists from dynamic contrast-enhanced MR lymphangiography studies, which included T2-weighted and dynamic contrast-enhanced T1-weighted images, conventional lymphangiography studies were also evaluated.</div></div><div><h3>Results</h3><div>We identified 16 patients (12 male): 8 infants, 6 children, and 2 adults. 12 patients had cardiac surgery including Fontan (<em>n</em> = 5), hemi-Fontan (<em>n</em> = 1), Glenn (n = 1), and other cardiac surgeries (n = 5). Presenting symptoms included chylothorax, plastic bronchitis, chylous ascites, protein losing enteropathy, pericardial effusion, lymphedema, and anasarca. Two patients died (12 %) by the time of data collection. T2-weighted MR imaging demonstrated lymphatic edema in all patients. T1-weighted dynamic imaging revealed abnormal pulmonary and/or mesenteric lymphatic perfusion in 15 patients (88 %) across intranodal, intrahepatic, and intramesenteric access types. The thoracic duct was tortuous and/or dilated in most cases. Conventional lymphangiography confirmed thoracic duct obstruction.</div></div><div><h3>Conclusion</h3><div>This is a descriptive study of central lymphatic diseases in patients with Trisomy 21, congenital heart disease and clinical evidence of lymphatic dysfunction. Common findings in these patients include retrograde dermal lymphatic flow, pulmonary and mesenteric lymphatic perfusion as well as the presence of a dilated and tortuous duct.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110627"},"PeriodicalIF":1.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-25DOI: 10.1016/j.clinimag.2025.110628
Christine Lamoureux , Shwan Kim , Patrick McGaughey , Edward Callaway , Zeljko Velichkovich , Joshua Morais , Sloan Miller
{"title":"Quality improvement initiative to increase radiologist reporting of the Alberta stroke program early CT score (ASPECTS)","authors":"Christine Lamoureux , Shwan Kim , Patrick McGaughey , Edward Callaway , Zeljko Velichkovich , Joshua Morais , Sloan Miller","doi":"10.1016/j.clinimag.2025.110628","DOIUrl":"10.1016/j.clinimag.2025.110628","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110628"},"PeriodicalIF":1.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Multiparametric MRI and clinical factors for predicting early recurrence of breast cancer after modified radical mastectomy","authors":"Quan-hua Chen , Chongze Yang , Lan-hui Qin , Yan-ling Liang , Wei-wei Jiang , Jin-yuan Liao","doi":"10.1016/j.clinimag.2025.110625","DOIUrl":"10.1016/j.clinimag.2025.110625","url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether preoperative multiparametric MRI features and clinicopathological factors can predict early recurrence in breast cancer patients following modified radical mastectomy (MRM).</div></div><div><h3>Materials and methods</h3><div>This retrospective study included 132 patients who underwent MRM at two hospitals from January 2012 to December 2022. Patients were classified into early recurrence (disease-free survival ≤3 years, <em>n</em> = 86) or late recurrence (>3 years, <em>n</em> = 46). We collected preoperative MRI features (tumor size, morphology, enhancement patterns, apparent diffusion coefficient (ADC) values, early enhancement rate, time-signal intensity curves) and clinical/pathological factors (age, menstruation status, neoadjuvant chemotherapy, T/N/TNM stage, tumor grade, axillary nodal involvement, vascular/nerve/nipple/skin invasion, ER, PR, HER-2, Ki-67, molecular subtype, and adjuvant therapies). Univariate and multivariate analyses (binary logistic and Cox regression) identified independent predictors of early recurrence and their impact on disease-free survival. Predictive accuracy was assessed by ROC curves.</div></div><div><h3>Results</h3><div>Significant factors associated with early recurrence (<em>P</em> < 0.05) included tumor size, ADC value, early enhancement rate, axillary lymph node metastasis, T and TNM stage, vascular invasion, ER, PR, HER-2, molecular subtype, and endocrine therapy. Multivariate analysis identified early enhancement rate, lower ADC value, and larger tumor diameter as independent predictors (AUC = 0.899). These MRI factors, together with lack of endocrine therapy, also independently influenced disease-free survival.</div></div><div><h3>Conclusion</h3><div>Preoperative multiparametric MRI features, especially early enhancement rate and tumor size, combined with endocrine therapy status, can predict early recurrence, enhancing prognosis for patients undergoing MRM.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110625"},"PeriodicalIF":1.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-15DOI: 10.1016/j.clinimag.2025.110619
Ji Young Jeon , So Hyun Park , Hee Young Lee
{"title":"Corrigendum to “Critical radiology results in thoracic imaging; categorization by urgency and clinical outcome” [Clin Imaging volume 126 (October 2025)/110594]","authors":"Ji Young Jeon , So Hyun Park , Hee Young Lee","doi":"10.1016/j.clinimag.2025.110619","DOIUrl":"10.1016/j.clinimag.2025.110619","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110619"},"PeriodicalIF":1.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-15DOI: 10.1016/j.clinimag.2025.110622
Andrew Kim , Sara Strauss , Gayle Salama
{"title":"CT-guided paramaxillary glossopharyngeal nerve block: A novel and potentially safer approach for diagnostic confirmation and temporary treatment of glossopharyngeal neuralgia","authors":"Andrew Kim , Sara Strauss , Gayle Salama","doi":"10.1016/j.clinimag.2025.110622","DOIUrl":"10.1016/j.clinimag.2025.110622","url":null,"abstract":"<div><div>The glossopharyngeal nerve block is an interventional technique utilized for head and neck pain management in the setting of glossopharyngeal neuralgia, dental procedures, awake endotracheal intubations, and post-pharyngeal surgery. This procedure is traditionally performed with landmark technique or ultrasound-guided techniques, all of which are associated with potential risks and complications for the patient. We report the novel technique of a CT-guided paramaxillary approach glossopharyngeal nerve block, which has not been previously reported, eliminates the trans-parotid trajectory, and reduces potential risks and complications associated with other established techniques, particularly those related to the parotid gland, including intraparotid facial nerve injury.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110622"},"PeriodicalIF":1.5,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145097891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-09-13DOI: 10.1016/j.clinimag.2025.110616
Benjamin D Simon, Stephanie A Harmon, Baris Turkbey
{"title":"Reply to \"A critical appraisal and methodological inquiry into an automated multimodal deep learning model for predicting biochemical recurrence in prostate cancer\".","authors":"Benjamin D Simon, Stephanie A Harmon, Baris Turkbey","doi":"10.1016/j.clinimag.2025.110616","DOIUrl":"https://doi.org/10.1016/j.clinimag.2025.110616","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":" ","pages":"110616"},"PeriodicalIF":1.5,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Common applications of noncosmetic dermatologic sonography: A comprehensive overview","authors":"Mohammadreza Tahamtan , Shahriar Rahmani , Hadi Koohi , Faezeh Khorasanizadeh , Khadijeh Shirazkeytabar , Elnaz Pourgholi , Ximena Wortsman","doi":"10.1016/j.clinimag.2025.110608","DOIUrl":"10.1016/j.clinimag.2025.110608","url":null,"abstract":"<div><h3>Purpose</h3><div>This review aims to highlight the increasing role of ultrasound in dermatology, emphasizing its utility in assessing skin and nail lesions. It focuses on the technological advancements and research driving its adoption as a safe, cost-effective, and non-invasive diagnostic tool.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive review of the literature, focusing on the technical aspects of dermatologic ultrasound, including real-time visualization, color Doppler for vascularity detection, and high axial spatial resolution. The ultrasonographic patterns of common benign and malignant conditions, inflammatory diseases, vascular anomalies, and nail lesions were analyzed.</div></div><div><h3>Results</h3><div>Ultrasound provides detailed real-time imaging, enabling accurate diagnosis and treatment planning for various dermatologic conditions. Key findings include the identification of characteristic ultrasonographic patterns for skin neoplasms, inflammatory diseases, and vascular malformations, as well as its efficacy in evaluating nail lesions.</div></div><div><h3>Conclusions</h3><div>Dermatologic ultrasound is a valuable tool for early diagnosis and management of skin and nail conditions. Its ability to visualize structural and vascular features in real-time improves diagnostic accuracy, making it an essential addition to dermatologic practice. Knowledge of ultrasonographic patterns can significantly benefit patient care.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"127 ","pages":"Article 110608"},"PeriodicalIF":1.5,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145097889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}