Clinical ImagingPub Date : 2025-04-24DOI: 10.1016/j.clinimag.2025.110486
Russ Guidry , Dakota Williams , Matthew D. Raymond , Andrew J. Gunn , Yufeng Li , Aliaksei Salei
{"title":"Same day discharge versus overnight observation after transarterial embolization: a retrospective study on mortality and readmission rates","authors":"Russ Guidry , Dakota Williams , Matthew D. Raymond , Andrew J. Gunn , Yufeng Li , Aliaksei Salei","doi":"10.1016/j.clinimag.2025.110486","DOIUrl":"10.1016/j.clinimag.2025.110486","url":null,"abstract":"","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"122 ","pages":"Article 110486"},"PeriodicalIF":1.8,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143891832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-15DOI: 10.1016/j.clinimag.2025.110484
Nabih Nakrour , Rory L. Cochran , Nathaniel David Mercaldo , William Bradley , Leo L. Tsai , Priyanka Prajapati , Robert Grimm , Heinrich von Busch , Wei-Ching Lo , Mukesh G. Harisinghani
{"title":"Impact of artificial intelligence assisted lesion detection on radiologists' interpretation at multiparametric prostate MRI","authors":"Nabih Nakrour , Rory L. Cochran , Nathaniel David Mercaldo , William Bradley , Leo L. Tsai , Priyanka Prajapati , Robert Grimm , Heinrich von Busch , Wei-Ching Lo , Mukesh G. Harisinghani","doi":"10.1016/j.clinimag.2025.110484","DOIUrl":"10.1016/j.clinimag.2025.110484","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare prostate cancer lesion detection using conventional and artificial intelligence (AI)-assisted image interpretation at multiparametric MRI (mpMRI).</div></div><div><h3>Materials and methods</h3><div>A retrospective study of 53 consecutive patients who underwent prostate mpMRI and subsequent prostate tissue sampling was performed. Two board-certified radiologists (with 4 and 12 years of experience) blinded to the clinical information interpreted anonymized exams using the PI-RADS v2.1 framework without and with an AI-assistance tool. The AI software tool provided radiologists with gland segmentation and automated lesion detection assigning a probability score for the likelihood of the presence of clinically significant prostate cancer (csPCa). The reference standard for all cases was the prostate pathology from systematic and targeted biopsies. Statistical analyses assessed interrater agreement and compared diagnostic performances with and without AI assistance.</div></div><div><h3>Results</h3><div>Within the entire cohort, 42 patients (79 %) harbored Gleason-positive disease, with 25 patients (47 %) having csPCa. Radiologists' diagnostic performance for csPCa was significantly improved over conventional interpretation with AI assistance (reader A: AUC 0.82 vs. 0.72, <em>p</em> = 0.03; reader B: AUC 0.78 vs. 0.69, p = 0.03). Without AI assistance, 81 % (<em>n</em> = 36; 95 % CI: 0.89–0.91) of the lesions were scored similarly by radiologists for lesion-level characteristics, and with AI assistance, 59 % (26, 0.82–0.89) of the lesions were scored similarly. For reader A, there was a significant difference in PI-RADS scores (<em>p</em> = 0.02) between AI-assisted and non-assisted assessments. Signficant differences were not detected for reader B.</div></div><div><h3>Conclusion</h3><div>AI-assisted prostate mMRI interpretation improved radiologist diagnostic performance over conventional interpretation independent of reader experience.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"122 ","pages":"Article 110484"},"PeriodicalIF":1.8,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143854653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-10DOI: 10.1016/j.clinimag.2025.110481
Elliot K. Fishman , Philippe Soyer , David B. Hellmann , Linda C. Chu
{"title":"The radiologist and data: Do we add value or is data just data?","authors":"Elliot K. Fishman , Philippe Soyer , David B. Hellmann , Linda C. Chu","doi":"10.1016/j.clinimag.2025.110481","DOIUrl":"10.1016/j.clinimag.2025.110481","url":null,"abstract":"<div><div>Artificial intelligence in radiology critically depends on vast amounts of quality data, and there are controversies surrounding the topic of data ownership. In the current clinical framework, the secondary use of clinical data should be treated as a form of public good to benefit future patients. In this article, we propose that the physicians' input in data curation and interpretation adds value to the data and is crucial for building clinically relevant artificial intelligence models.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"122 ","pages":"Article 110481"},"PeriodicalIF":1.8,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-09DOI: 10.1016/j.clinimag.2025.110471
Jing Chen , Linlin Sun , Yinan Chen , Jueqian Shi , Yu Zhang , Lei Zhu , Bowen Ding , Chengyu Ding , Huiyuan Zhu , Li Zhu , Hong Yu
{"title":"Imaging features and preoperative diagnostic insights of esophageal schwannomas as a rare type","authors":"Jing Chen , Linlin Sun , Yinan Chen , Jueqian Shi , Yu Zhang , Lei Zhu , Bowen Ding , Chengyu Ding , Huiyuan Zhu , Li Zhu , Hong Yu","doi":"10.1016/j.clinimag.2025.110471","DOIUrl":"10.1016/j.clinimag.2025.110471","url":null,"abstract":"<div><h3>Purpose</h3><div>We aimed to analyze and summarize the key features of esophageal schwannomas to provide new insights into preoperative diagnosis and enhance clinical recognition.</div></div><div><h3>Methods</h3><div>Twenty-one consecutive patients with pathologically confirmed esophageal schwannoma who underwent surgical resection between January 2013 and January 2023 were enrolled. Imaging results from barium swallow, CT, MRI, <sup>18</sup>F-FDG PET-CT, esophagoscopy, and endoscopic ultrasound were compiled and analyzed.</div></div><div><h3>Results</h3><div>Our cohort comprised 10 males and 11 females, with mean age of 55.86 ± 9.09 years. The mean tumor size was 5.69 ± 1.32 cm, with tumors commonly located in the upper to middle esophagus. 83.3 % (10/12) presented smooth filling defects with intact canal walls in barium meal. Most tumors (71.4 %, 15/21) were oval-shaped, exhibiting intracavitary growth with well-defined borders. Mild enhancement was observed on CT with pre-contrast attenuation of 36.0 ± 53.87 HU and post-contrast enhancement of 52.75 ± 7.45 HU. Most lesions showed plateau dynamic enhancement on MRI (85.7 %, 6/7). Air crescent signs (95.2 %, 20/21) and fascicular signs (87.5 %, 7/8) were observed in most cases. Neither calcifications nor target signs were observed, and cystic changes were infrequent. All lesions showed high uptake on PET-CT (SUVmax: 11.19 ± 3.41). Endoscopic lesions typically exhibit smooth surfaces, soft textures, and colors ranging from normal to slightly lighter hues (94.7 %, 18/19). Endoscopic ultrasound indicated minimal blood flow within lesions (53.8 %, 7/13), and elastography displayed a blue-green pattern (100 %, 5/5).</div></div><div><h3>Conclusion</h3><div>Esophageal schwannomas exhibit distinct imaging characteristics. MRI provides additional diagnostic information for more accurate evaluation, while high metabolic activity on PET-CT may mimic malignancy.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"122 ","pages":"Article 110471"},"PeriodicalIF":1.8,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143844243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-07DOI: 10.1016/j.clinimag.2025.110470
Nina Nariman , Laura Avery
{"title":"On the forefront of worldly radiological innovation, education and mentorship – A tribute to Dr. Theresa McLoud","authors":"Nina Nariman , Laura Avery","doi":"10.1016/j.clinimag.2025.110470","DOIUrl":"10.1016/j.clinimag.2025.110470","url":null,"abstract":"<div><div>Dr. Theresa McLoud is a true pioneer in thoracic radiology. Her considerable involvement in numerous radiological societies is reflected by her many leadership positions and the esteemed awards she has received. By participating in prevalent conversations with other leaders in the field, Dr. McLoud has shown true devotion to the advancement of radiology across the globe. Her passion for mentorship has impacted the lives of many students, residents, and trainees. Dr. McLoud balances compassion with instruction by treating her trainees with kindness while ensuring high academic and professional standards. Dr. McLoud has shown steadfast dedication to the advancement of radiology in all aspects of her career; she is genuinely an extraordinary trailblazer in radiology.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"122 ","pages":"Article 110470"},"PeriodicalIF":1.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-01DOI: 10.1016/j.clinimag.2025.110469
Eitan Sosner , Bertin Mathai , Abraham Bordon , Kenny Ye , Renee M. Moadel , Linda B. Haramati , Matthew S. Lazarus
{"title":"Long-term mortality from imaging-diagnosed pulmonary embolism in women and men","authors":"Eitan Sosner , Bertin Mathai , Abraham Bordon , Kenny Ye , Renee M. Moadel , Linda B. Haramati , Matthew S. Lazarus","doi":"10.1016/j.clinimag.2025.110469","DOIUrl":"10.1016/j.clinimag.2025.110469","url":null,"abstract":"<div><div>Pulmonary embolism (PE) is a heterogeneous disease with variable severity. Risk factors and occurrence of PE differ in patients by gender, age, and comorbidity. Our goal was to determine long-term mortality in imaging diagnosed PE in men and women while accounting for differences in age and health status.</div><div>This was a retrospective study of adults imaged for PE with ventilation/perfusion scintigraphy or CT pulmonary angiography over a 7-year period at our multisite urban academic medical center. Electronic health records (EHR) were reviewed for patient data, including Charlson comorbidity index (CCI). Mortality at one-year was determined from EHR and National Death Index. Association between PE and survival was assessed using Cox proportional hazard model.</div><div>33,628 patients (55yo ± 19, 69 % women) were imaged for PE, 9.5 % of exams were positive. One-year mortality for the cohort was 9.9 % for women vs. 16.8 % for men, <em>p</em> < 0.001. Women with PE had higher increased one-year mortality (HR 2.75[2.48–3.06]) than men with PE (HR:1.38[1.21–1.58]). Women with PE also had higher hazard ratio after inclusion of age and CCI as covariates in the Cox proportional hazard model (women HR 1.68 [1.51–1.86] versus men HR 1.20 [1.05–1.36]). The higher impact of PE on the mortality of women yielded a similar one-year mortality for women and men with PE, 21.9 % vs. 21.5 %, respectively (<em>P</em> = 0.83).</div><div>Positive PE study was associated with significantly increased one-year mortality, however this effect was much stronger in women. This gender difference persists after accounting for age and comorbidities.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"122 ","pages":"Article 110469"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-01DOI: 10.1016/j.clinimag.2025.110466
Gary Gu Tianyu , Sarah Tham Zhuling , Tammy Hui Lin Moey , Ching Boon Chye , Ian Tay Wei Ming
{"title":"Lateral-arm approach decreases clip migration in stereotactic breast biopsies","authors":"Gary Gu Tianyu , Sarah Tham Zhuling , Tammy Hui Lin Moey , Ching Boon Chye , Ian Tay Wei Ming","doi":"10.1016/j.clinimag.2025.110466","DOIUrl":"10.1016/j.clinimag.2025.110466","url":null,"abstract":"<div><h3>Aim</h3><div>Stereotactic-guided vacuum-assisted biopsy (STVAB) is the standard of care to biopsy mammographically detected breast lesions without a sonographic correlate. It can be performed using the conventional (CBA) or lateral-arm biopsy approach (LABA). Tissue marker (clip) placement is routinely done post-biopsy. Clip migration is frequently encountered in STVAB and can result in higher rates of positive margins and re-excision in subsequent surgery. We sought to compare clip migration rates between CBA and LABA.</div></div><div><h3>Materials and methods</h3><div>We performed a retrospective review of 347 cases performed at an Asian institution from 2021 to 2024, on predominantly dense breasts. We compared clip migration rates between CBA and LABA. Other factors that were known to contribute to clip migration were also studied, including breast density and hematoma size. Statistical analysis was done using Fisher's exact test, Mann–Whitney <em>U</em> test and linear regression models.</div></div><div><h3>Results</h3><div>A total of 347 biopsies were performed. CBA was performed for 297 (85.6 %) patients and LABA was performed for 50 (14.4 %). LABA was found to significantly reduce clip migration rates compared to CBA (4 % versus 25.9 %, <em>p</em> < 0.001). Breast density (<em>p</em> = 0.55) andhematoma size (<em>p</em> = 0.662) were not found to significantly affect clip migration rates.</div></div><div><h3>Conclusion</h3><div>We recommend utilizing LABA over CBA whenever technically possible if we wish to minimize clip migration.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"121 ","pages":"Article 110466"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143768056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-04-01DOI: 10.1016/j.clinimag.2025.110468
Jesús David Brito-Mugno , Jairo Esteban Mahecha , María Camila Buitrago-Pedraza , Carlos Andrés Corredor-Silva , Felipe Aluja-Jaramillo
{"title":"Optimizing patellar imaging: What every radiologist should know","authors":"Jesús David Brito-Mugno , Jairo Esteban Mahecha , María Camila Buitrago-Pedraza , Carlos Andrés Corredor-Silva , Felipe Aluja-Jaramillo","doi":"10.1016/j.clinimag.2025.110468","DOIUrl":"10.1016/j.clinimag.2025.110468","url":null,"abstract":"<div><div>The patella, biggest of all sesamoid bones, is an integral part of knee biomechanical function. It is a pivot for the quadriceps, enabling them to stabilize and contract during motion. With its complex shape, comprising many stabilizing structures and significant parts of articulation, its evaluation and analysis become a challenging issue in radiology departments worldwide.</div><div>In this article, its evaluation with conventional radiography and Multidetector Computed Tomography, and its role in patellar pathology, have been discussed. In an extended discussion, key measurements, such as the trochlear groove angle, Merchant's congruence angle, and TT-TG distance, in diagnosing trochlear dysplasia, lateral patellar dislocation, and patellofemoral instability, have been discussed in detail.</div><div>Certain radiological report-enhancing techniques and standardization have been discussed, providing a pragmatic view for maximizing such a pathology's diagnosis and management. The intention of this article is not to prescribe definite methodologies but to introduce tools for a correct patellar pathology and its implications in a reliable manner.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"121 ","pages":"Article 110468"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical ImagingPub Date : 2025-03-31DOI: 10.1016/j.clinimag.2025.110467
Alan A. Sag , Ernest Barral , James Ronald , Jeremy Force , Nicole A. Larrier , Julia Visgauss , Charles Y. Kim
{"title":"Cryoablation of bone, soft tissue, and nerve in the setting of uninterrupted systemic cancer therapies","authors":"Alan A. Sag , Ernest Barral , James Ronald , Jeremy Force , Nicole A. Larrier , Julia Visgauss , Charles Y. Kim","doi":"10.1016/j.clinimag.2025.110467","DOIUrl":"10.1016/j.clinimag.2025.110467","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess safety of cryoablation in cancer patients receiving uninterrupted systemic cancer therapies with regard to wound healing.</div></div><div><h3>Materials and methods</h3><div>In this single-institution IRB-approved retrospective study, all patients (29/50 (58 %) female, mean age 61.9 +/− 11.3 years) undergoing cryoablation of bone, soft tissue, or nerve for symptomatic treatment while on uninterrupted systemic therapy between 2019 and 2022 were included for analysis. Charts were reviewed to identify post-cryoablation infection or wound healing complication within 90 days after cryoablation. All patients received routine prophylactic intraprocedural antibiotics; no patients were prescribed antibiotics post-procedure.</div></div><div><h3>Results</h3><div>Sixty-nine cryoablations of bone (42/69, 61 %), soft tissue (17/69, 25 %) and nerve (10/69,14 %) were performed without interrupting ongoing traditional chemotherapy, targeted therapy, immunotherapy, investigational clinical trial therapy, or hormone therapy in 32/69 (35 %), 26/69 (38 %), 14/69 (20 %), 5/69 (7 %) respectively. There were 3/69 (4 %) patients with neutropenia (defined as absolute neutrophil count <1500 cells/mL). Agents known to delay wound healing (such as VEGF/R, E/FGFR inhibitors) or chronic steroids were not interrupted in 9/69 (13 %) and 36/69 (52 %) respectively. Prior to cryoablation, the treatment zone was previously embolized in 8/69 (12 %) and irradiated in 34/69 (49 %). By mean clinical follow up of 41 days (range, 1–98 days post-cryoablation), no procedure-site infections nor wound healing complications occurred.</div></div><div><h3>Conclusion</h3><div>Wound healing abnormalities were not observed when performing percutaneous cryoablation with uninterrupted systemic therapies in this study, even in treatment zones that had received radiotherapy and embolization.</div></div>","PeriodicalId":50680,"journal":{"name":"Clinical Imaging","volume":"121 ","pages":"Article 110467"},"PeriodicalIF":1.8,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}