Clinical Implant Dentistry and Related Research最新文献

{"title":"Bone Morphogenetic Protein (BMP) 9 Outperforms BMP2 in Osteogenesis and Osseointegration: In Vitro and In Vivo","authors":"Hee-seung Han,&nbsp;Dong Woo Lee,&nbsp;Yu-Bin Kim,&nbsp;Sanghui Seok,&nbsp;Jeong Yeon Park,&nbsp;Sungtae Kim,&nbsp;Jue Yeon Lee,&nbsp;Yoon Jeong Park,&nbsp;Chong Pyung Chung,&nbsp;Young-Dan Cho","doi":"10.1111/cid.70135","DOIUrl":"10.1111/cid.70135","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study compared the osteogenic mechanisms and preclinical efficacy of bone morphogenetic protein 9 (BMP9) and BMP2 in vitro and in a beagle peri-implant defect model in vivo.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>In vitro, MC3T3-E1 preosteoblasts were treated with BMP2 or BMP9 to assess osteogenic gene expression (<i>Col1, Runx2, Alp, Ocn</i>) by real-time PCR, Smad1/5/9 phosphorylation by western blotting, and osteogenesis by alkaline phosphatase (ALP) and Alizarin Red S staining. In vivo, saddle-type peri-implant defects were created in beagle mandibles and treated with a collagenated xenograft matrix with or without BMP2 or BMP9 (150 μg/site). After 8 weeks, implant stability, micro-CT, histomorphometry, and osseointegration parameters were analyzed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>BMP9 significantly enhanced osteogenic gene expression, Smad1/5/9 phosphorylation, ALP activity, and mineralization compared to BMP2. In vivo, BMP9 yielded the highest implant stability values, greater defect fill, and higher bone volume fraction, bone mineral density, and bone-to-implant contact.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>BMP9 showed stronger osteoinductive potential than BMP2, resulting in improved bone regeneration and osseointegration. These findings suggest that BMP9 is a promising growth factor for improving dental implant outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12974554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonication-Assisted Sequential Chemical Removal of Mature Biofilm on Retrieved Titanium Healing Abutments","authors":"Eyşan Çetinsoy,&nbsp;Bülent Gökçe,&nbsp;Timur Köse,&nbsp;Ali Gürkan","doi":"10.1111/cid.70131","DOIUrl":"10.1111/cid.70131","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Potential effectiveness of ultrasonication (US) with different chemical solutions on the decontamination of titanium implant healing abutments (HAs) and their surface characteristics was investigated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Ninety-five HAs, representing two distinct brands/designs, were retrieved from patients after 4–6 weeks for the present study. They were precleaned by immersing in enzymatic detergent (ED) and randomized into five groups: autoclaving only (control), US in 40°C tap water and autoclaving, US in 40°C 1% sodium hypochlorite (SH) and autoclaving, US in 80°C citric + maleic + lactic acid (CA) solution and autoclaving, US in 40°C ED and autoclaving. HAs were stained and photographed from lateral and occlusal aspects before and after decontamination. Stained areas were calculated and scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) analyses were conducted to assess surface morphology and elemental composition.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Control group showed the lowest debridement potential (mean 54.4%) and highest residual contamination. SH almost entirely removed the debris (mean 99.7%, Brand1: 99.6%, Brand2: 99.9%) showing an outperforming cleansing efficacy among all groups (<i>p</i> &lt; 0.05). SEM and EDS analyses demonstrated that surface morphology and elemental composition of decontaminated surfaces in SH group was similar to that of unused HAs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>After precleaning HAs by soaking in ED, 1% SH, used in combination with US, can be preferred for decontaminating HAs due to its superior cleaning efficiency and minimal surface alteration regardless of HA macrogeometry. In cases where placing unused HAs is not feasible, this three-step protocol may present an efficient and cost-effective alternative for at least one reuse cycle.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147380006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peri-Implant Reconstruction With Autogenous Bone and Electrolytic Therapy: A Randomized Controlled Clinical Trial","authors":"Algirdas Puisys,&nbsp;Samuel Akhondi,&nbsp;Egle Vindasiute-Narbute,&nbsp;Tadas Zvirblis,&nbsp;German O. Gallucci,&nbsp;Ignacio Pedrinaci","doi":"10.1111/cid.70123","DOIUrl":"10.1111/cid.70123","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the efficacy of peri-implant reconstructive therapy using autogenous tuberosity bone grafts, with or without adjunctive electrolytic therapy, as part of surgical treatment for peri-implantitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This randomized controlled clinical trial included 31 patients diagnosed with peri-implantitis. Participants were assigned to either a control group receiving mechanical debridement and bone grafting or a test group undergoing additional electrolytic cleaning (EC). Clinical parameters assessed included probing pocket depth (PPD) at mesial, buccal, distal, and lingual sites, gingival index (GI), and bleeding on probing (BOP), with measurements taken at baseline and at 12 months post-treatment. Radiographic assessments were conducted at baseline and at the 1-year follow-up to evaluate bone defect fill at mesial and distal sites. Intraoperative bone fill was also assessed at mesial, buccal, distal, and lingual sites on the day of surgery and 6 months post-surgery.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both groups exhibited statistically significant PPD reductions at all sites and improvements in GI and BOP compared to baseline. No statistically significant differences between groups were found for these clinical parameters. Radiographically, the test group demonstrated significantly greater mean bone defect fill at the mesial site compared to the control group, with gains of 4.6 mm (±1.10 mm) versus 2.5 mm (±1.77 mm), respectively (<i>p</i> = 0.002). Intraoperatively, the distal site showed a mean gain of 4.7 mm (±1.41 mm) in the test group and 3.8 mm (±1.72 mm) in the control group after 6 months; however, this difference was not statistically significant (<i>p</i> = 0.069). Suppuration resolved completely in both groups after 1 year (<i>p</i> &lt; 0.001), with no significant differences between groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Peri-implant reconstructive therapy using autogenous bone grafts led to statistically significant clinical and radiographic improvements in both groups. The addition of electrolytic cleaning did not result in significant differences. The absence of histological data, which could not be obtained in this human trial, remains a limitation for confirming re-osseointegration.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic Occlusal Design Using Jaw Motion Data for Maxillary Full-Arch Implant Rehabilitation: A Retrospective Study","authors":"Liangfu Huang,&nbsp;Huiyu Yao,&nbsp;YanBin Sun,&nbsp;Qingyu Yu,&nbsp;Jiayan Li,&nbsp;Xi Ding,&nbsp;Jianjing Huang","doi":"10.1111/cid.70133","DOIUrl":"10.1111/cid.70133","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the clinical efficacy of prostheses designed using mandibular motion analysis in maxillary full-arch implant rehabilitation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty patients were assigned to a study group (<i>n</i> = 10), receiving prostheses designed with dynamic occlusal data from an electronic jaw motion analyzer (JMA), or a control group (<i>n</i> = 10) using conventional static digital workflows. Between-group differences in occlusal adjustment depth (MAE), area, and chairside time were analyzed by independent t-tests. Within the study group, the stability of mandibular movement paths (provisional vs. post-restoration) was assessed using paired t-tests. Oral health-related quality of life (OHRQoL) was evaluated using the OHIP-14 questionnaire. Effect sizes were calculated as Hedges’ <i>g</i>.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study group exhibited significantly lower occlusal adjustment depth (163.26 ± 31.42 μm vs. 213.99 ± 56.38 μm; <i>p</i> = 0.030, Hedges’ <i>g</i> = 1.06) and adjustment area (95.93 ± 30.27 mm² vs. 129.86 ± 25.82 mm²; <i>p</i> = 0.020, <i>g</i> = 1.16) compared to the control group. Chairside adjustment time was reduced by approximately 30% (23.8 ± 7.8 min vs. 33.8 ± 8.0 min; <i>p</i> = 0.074, <i>g</i> = 1.15). No significant changes in parameters of mandibular movement paths were observed within the study group post-restoration (all <i>p</i> &gt; 0.05). OHIP-14 scores were significantly better in the study group for “Meal interruption”, “Relaxation difficulty” (<i>p</i> = 0.041), reflecting improved OHRQoL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Integrating dynamic mandibular motion data into prosthesis design reduces clinical adjustments, improves OHRQoL, and preserves inherent movement patterns, demonstrating a promising approach to optimize functional outcomes in full-arch implant rehabilitation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>Integrating dynamic mandibular motion data into digital prosthesis design offers a clinically valuable strategy that minimizes occlusal adjustments, supports functional stability, and enhances patient-reported quality of life in full-arch implant rehabilitation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147350084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal Clinical Outcomes of Tissue-Level Dental Implants in a Periodontal Practice: A Retrospective Study","authors":"Hongmin Lai,&nbsp;Ming-Tsuen Lin,&nbsp;Ting-Yu Lin,&nbsp;Sam Li-Sheng Chen,&nbsp;Tony Hsiu-Hsi Chen,&nbsp;Amy Ming-Fang Yen","doi":"10.1111/cid.70132","DOIUrl":"10.1111/cid.70132","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This study aimed to evaluate the 28-year cumulative success and survival rates of tissue-level implants placed by a periodontist in Taiwan.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>In this retrospective cohort study, 685 tissue-level implants placed in 199 patients between 1996 and 2024 were analyzed. A success was defined as the absence of probing depth (PD) ≥ 5 mm nor implant loss—while survival referred to the presence and clinical function of the implant. Kaplan–Meier analysis was used to estimate cumulative rates at both implant and patient levels. Potential risk factors, including patient demographics, smoking status, implant characteristics, periodontal status, and frequency of maintenance visits, were examined using Cox proportional hazards regression models.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>At 28 years, the cumulative success rates were 71.00% at the implant level and 38.02% at the patient level, while the survival rates were 92.58% and 81.38%, respectively. Multivariable regression analysis identified male and severe periodontitis as significant predictors of peri-implant disease or implant loss. In contrast, more frequent maintenance visits were protective. Treatment outcomes for peri-implantitis were variable and difficult to predict.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Tissue-level implants demonstrated favorable long-term clinical performance in a Taiwanese population, with success and survival rates comparable to those reported in Western cohorts. These findings underscore the importance of periodontal health and regular maintenance care in sustaining implant longevity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12947611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147313466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicians' Stress Levels During Soft Tissue Augmentation Using Autogenous Connective Tissue Grafts: A Pilot Study","authors":"Anina N. Zuercher,&nbsp;Franz J. Strauss,&nbsp;Rawen Smirani,&nbsp;Ronald E. Jung,&nbsp;Reinhard Gruber,&nbsp;Daniel S. Thoma","doi":"10.1111/cid.70130","DOIUrl":"10.1111/cid.70130","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To quantify intraoperative stress responses in clinicians performing mucogingival surgery using subepithelial connective tissue grafts (SCTG) for mucosal thickening by combining physiological and psychological measures and to explore the feasibility of stress monitoring in this surgical context.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Eleven clinicians performed 14 SCTG procedures. Physiological stress was assessed using heart rate (HR) and salivary cortisol measured at multiple time points from morning baseline through the evening. Psychological stress and workload were evaluated using validated questionnaires, namely the short-form State–Trait Anxiety Inventory (STAI-6) and the Surgery Task Load Index (SURG-TLX). Data were analyzed with linear mixed-effects models to account for repeated measures in this exploratory pilot study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Heart rate showed a significant overall time effect (<i>p</i> &lt; 0.001), with transient increases during incision, flap preparation and graft harvesting, followed by recovery during suturing. Salivary cortisol levels decreased progressively throughout the day (<i>p</i> &lt; 0.01), consistent with normal diurnal variation and indicating the absence of sustained endocrine stress. Heart rate and cortisol patterns did not differ by clinician experience (&lt; 3 years or ≥ 3 years). STAI-6 scores remained stable over time, whereas SURG-TLX responses identified high mental demand and task complexity as the dominant contributors to perceived workload.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>SCTG procedures are associated with short-term physiological stress activation without concomitant increases in perceived anxiety, suggesting an adaptive stress and well-regulated responses among clinicians.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Clinical Significance</h3>\u0000 \u0000 <p>SCTG causes short-term physical stress, but clinicians appear to cope well and do not feel more anxious while performing them. Characterizing stress dynamics during mucogingival surgery may help inform future research on clinician performance, fatigue, and procedural safety in soft tissue augmentation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12937924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147291873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prosthetic Emergence Angles and Implant Outcomes: A Retrospective Study With at Least 5 Years of Follow-Up","authors":"Paolo Dellacasa,&nbsp;Lucia Schiavon,&nbsp;Maria Menini,&nbsp;Paolo Pesce,&nbsp;Cristiano Tomasi,&nbsp;Eriberto Bressan","doi":"10.1111/cid.70127","DOIUrl":"10.1111/cid.70127","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>The influence of prosthetic emergence angles on peri-implant tissue stability has become a topic of growing interest. While wide emergence angles have been associated with increased marginal bone loss (MBL) and peri-implantitis, available evidence is limited and largely based on studies using prefabricated abutments. This retrospective study aimed to evaluate the impact of customized implant-supported fixed dental prostheses (iFDPs) emergence angles on peri-implant MBL and peri-implant health after a minimum of 5 years of follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Patients rehabilitated with single or multiple iFDPs between 2010 and 2019 were retrospectively screened. Inclusion required a minimum follow-up of 5 years. Clinical parameters and radiographic marginal bone loss were assessed. Emergence angles (mesial, distal, buccal, palatal/lingual) were measured and categorized as &lt; 40°, 40°–59°, or ≥ 60°. Multivariable regression models adjusted for smoking and follow-up duration analyzed associations between emergence angles, MBL, and peri-implantitis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifty-two patients with 112 implants met the inclusion criteria. Mean emergence angles were: mesial 43.9°, distal 40.6°, buccal 49.5°, and palatal 45.8°. Overall, peri-implant tissues remained stable, with mean bone loss values ≤ 0.8 mm and mean PPD 1.8–3.9 mm over time. No significant correlation was found between emergence angle categories and MBL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Prosthetic emergence angle did not significantly influence peri-implant bone loss or peri-implantitis when customized abutments were used. Individualized abutments might mitigate risks associated with wide emergence angles.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 2","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12933279/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147286768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Materials in Implant-Supported Partial Fixed Dental Prostheses: A Randomized Controlled Trial","authors":"Jan Kowar,&nbsp;Alberto Turri,&nbsp;Victoria Stenport,&nbsp;Christina Stervik,&nbsp;Sargon Barkarmo","doi":"10.1111/cid.70129","DOIUrl":"10.1111/cid.70129","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This randomized controlled trial compared the clinical performances after 1 year of implant-supported, partial fixed dental prostheses (FDPs) fabricated from monolithic high-translucency zirconia, veneered high-translucency zirconia, and titanium-ceramic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Forty-nine adult participants who required posterior implant-supported FDPs were randomly assigned to three groups: monolithic zirconia (MZ, <i>n</i> = 23 FDPs), veneered zirconia (VZ, <i>n</i> = 20 FDPs), and veneered titanium (TC; <i>n</i> = 20 FDPs). Clinical and radiographical evaluations were performed at the 1-year follow-up, assessing prosthetic and implant survival, biological and technical complications, and marginal bone levels.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 59 FDPs were examined at follow-up (MZ, <i>n</i> = 21; VZ, <i>n</i> = 20; TC, <i>n</i> = 18). The overall prosthetic survival rate was 96.8%. One FDP in the VZ group failed due to a framework fracture, and one FDP in the TC group was replaced due to extensive chipping. Survival rates were 100% for MZ, 95% for VZ, and 95% for TC. Technical complications occurred in 6.8% of the FDPs, with chipping being the most frequent complication in the TC (11.1%) and VZ (5.0%) groups. Screw loosening occurred in one MZ FDP (4.8%). No chipping was observed in the MZ group. The overall implant survival rate was 99.2%. Biological complications were minimal, with peri-implant mucositis observed in 8.3% of the FDPs. There were no statistically significant differences in marginal bone level changes between the groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Short-span, implant-supported, partial FDPs composed of monolithic zirconia, veneered zirconia, and titanium-ceramic demonstrate high clinical survival rates at the 1-year follow-up in posterior regions. Longer-term studies are needed to confirm the long-term durability and clinical performance levels of these FDPs.</p>\u0000 \u0000 <p><b>Trial Registration:</b> https://clinicaltrials.gov/study/NCT05296291.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12894104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146168505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Five Osteotomy Protocols on Implant Stability and Postoperative Anxiety: A Randomized Controlled Trial","authors":"Rozerin Konuklu,&nbsp;Sercan Küçükkurt","doi":"10.1111/cid.70125","DOIUrl":"10.1111/cid.70125","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This randomized controlled clinical trial compared five implant osteotomy techniques—high-speed drilling (800 rpm), moderate-speed drilling (300 rpm), ultra-low-speed drilling (50 rpm), osseodensification, and bone condensation—with respect to insertion torque (IT), early implant stability quotient (ISQ) progression, and immediate postoperative VAS-anxiety during early osseointegration.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Materials and Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;One hundred healthy adults each received a single identical macrodesign implant and were randomly allocated to five osteotomy protocols (&lt;i&gt;n&lt;/i&gt; = 20/group). Insertion torque was recorded at placement. ISQ was measured at placement (T0), 1 week (T1), 1 month (T2), 2 months (T3), and 3 months (T4). Immediate postoperative patient-reported anxiety was assessed using a 10-cm visual analog scale (VAS). Sites exhibiting IT &lt; 25 Ncm were prespecified for submerged healing and excluded from longitudinal stability analyses. The primary endpoint was the change in ISQ from T0 to T4, with multiplicity controlled using Bonferroni-adjusted pairwise comparisons.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A total of 100 implants were included in the final analyzed cohort. Four additional implants exhibited IT &lt; 25 Ncm at placement and were therefore excluded from longitudinal ISQ analyses according to the predefined protocol. Across the analyzed implants, all groups achieved mean IT values exceeding 30 Ncm and baseline ISQ values &gt; 80. Moderate-speed drilling (300 rpm) demonstrated the most consistent ISQ increase over time and achieved the highest stability at T4 (adjusted &lt;i&gt;p&lt;/i&gt; &lt; 0.05). High-speed drilling (800 rpm) produced the highest initial IT, particularly in high-density bone. Osseodensification showed transient mid-healing ISQ gains, whereas bone condensation exhibited a progressive decline in ISQ values. Immediate postoperative VAS-anxiety decreased significantly in all groups (&lt;i&gt;p&lt;/i&gt; &lt; 0.001); osseodensification was associated with higher residual anxiety, while bone condensation demonstrated the greatest reduction (adjusted &lt;i&gt;p&lt;/i&gt; &lt; 0.05).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Osteotomy technique influenced both mechanical stability trajectories and immediate postoperative patient-reported VAS-anxiety. Moderate-speed drilling at 300 rpm provided the most balanced stability profile within the 3-month follow-up. Osteotomy selection should be individualized according to bone density, mechanical requirements, and patient-related factors.&lt;/p&gt;\u0000 \u0000 &lt;p&gt;&lt;b&gt;Trial Registration:&lt;/b&gt; ClinicalTrials.gov ident","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Bone Microstructure Derived From CBCT and Marginal Bone Loss in a Platform-Switched Implant System: A 1-to-8-Year Retrospective Study","authors":"Wenxi Dong,&nbsp;Xinrui Lang,&nbsp;Jie Xia,&nbsp;Ying Yang,&nbsp;Fan Yang,&nbsp;Linhong Wang","doi":"10.1111/cid.70124","DOIUrl":"10.1111/cid.70124","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the relationship between cone-beam computed tomography (CBCT)-derived bone microstructure parameters and marginal bone loss (MBL) around platform-switched subcrestal implants over 1–8 years.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis assessed 142 platform-switched implants in 100 patients. CBCT-based bone microstructure parameters—bone volume (BV), tissue volume (TV), bone volume fraction (BV/TV), bone surface (BS), bone surface fraction (BS/BV), trabecular thickness (Tb.Th), and trabecular separation (Tb.Sp)—were measured in peri-implant and cervical regions. Radiographic MBL was evaluated at baseline (T0: prosthetic insertion) and follow-ups (T1: 1–3 years post-loading, T2: 3–8 years post-loading). Associations between bone microstructure parameters and MBL were analyzed using Generalized estimating equations (GEE).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>GEE analysis of 142 implants from 100 patients, adjusting for covariates, linked baseline bone microstructure to MBL at T0, T1 and T2. No significant associations were found at T0 or T1 (<i>p</i> &gt; 0.05). At T2, cervical bone microstructure parameters were not significant. However, peri-implant parameters were predictive: BV/TV was protective (B = −1.028, <i>p</i> = 0.0125), while BS/BV (B = 0.008, <i>p</i> = 0.0384) and Tb.Sp (B = 1.214, <i>p</i> = 0.0270) were significant risk factors for long-term MBL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Peri-implant BV/TV, BS/BV and Tb.Sp might be critical predictors of long-term MBL progression in platform-switched subcrestal implants, while cortical bone thickness has limited impact. CBCT-based bone microstructure analysis could aid MBL risk prediction and clinical management.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>This study has been registered in the Chinese Clinical Trial Registry, with the registration number ChiCTR2500098567</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"28 1","pages":""},"PeriodicalIF":4.0,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}