Clinical Implant Dentistry and Related Research最新文献

{"title":"Three-Dimensional Hard and Soft Tissue Healing at Implants With A Modified Neck Design: An In Vivo Preclinical Study","authors":"David Palombo,&nbsp;Federico Rivara,&nbsp;Liebert Parreiras Nogueira,&nbsp;Fabio Vignoletti,&nbsp;Javier Sanz Esporrin,&nbsp;Håvard Jostein Haugen,&nbsp;Mariano Sanz","doi":"10.1111/cid.70065","DOIUrl":"https://doi.org/10.1111/cid.70065","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To evaluate the three-dimensional hard and soft tissue healing around a modified dental implant presenting a tissue level connection and a convergent transmucosal neck (test), compared with a conventional bone level implant (control).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Sixteen test and 16 control implants were placed in 8 experimental animals, following a random allocation sequence. Peri-implant bone volume and surface, 360° bone to implant contact (360-BIC), peri-implant soft tissue volume, and buccal and lingual peri-implant soft tissue thickness, were evaluated through Micro-CT and digital volumetric analysis at 4 and 12 weeks of healing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the most coronal mm of the implant surface apical to the implant platform, both at 4 and 12 weeks, 360-BIC was higher at test implants. At 4 weeks, it was approximately 4 times higher (+303.26%; <i>∆</i> = 39.83%; <i>p</i> = 0.05) and at 12 weeks, 2.50 times higher (+151.8%; <i>∆</i> = 43.23%; <i>p</i> = 0.03). In the same area of interest, a statistically non-significant trend towards a higher 360° peri-implant bone volume was also observed in the test group, both at 4 weeks (+ 272.72%; <i>∆</i> = 8.70 mm³; <i>p</i> = 0.07) and 12 weeks (+ 154.54%; <i>∆</i> = 8.32 mm³; <i>p</i> = 0.09), being statistically significant only for the lingual bone volume at 4 weeks (+246.47%; <i>∆</i> = 5.94 mm³; <i>p</i> = 0.02). No significant differences were observed when comparing the soft tissue volumes and thicknesses among the two groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Test implants demonstrate superior 360-BIC and bone volumes around the most coronal implant surface, below the implant platform, while no relevant differences in soft tissue volumes and thickness were observed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144574004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Carbonate Apatite and Bone Mixture on Bone and Soft Tissue Integration in a Rat Implant Model","authors":"Tingyu Xie,&nbsp;Ikiru Atsuta,&nbsp;Ikue Narimatsu,&nbsp;Bin Ji,&nbsp;Kiyoshi Koyano,&nbsp;Yasunori Ayukawa","doi":"10.1111/cid.70077","DOIUrl":"https://doi.org/10.1111/cid.70077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Achieving stable bone regeneration and soft tissue integration is critical for the success of dental implants, especially in patients with alveolar bone defects. Carbonate apatite (CO₃Ap), a synthetic bone substitute, has emerged as a promising alternative due to its excellent osteoconductivity and biocompatibility. However, CO₃Ap lacks osteoinductive capacity, which limits its effectiveness in promoting bone regeneration on its own.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study aimed to evaluate the effects of a CO₃Ap–autogenous bone (AB) mixture on bone regeneration and soft tissue integration in a rat maxillary implant model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>Sixty rats underwent extraction of their maxillary molars, followed by titanium implant placement. The extraction sockets were filled with three different materials: CO₃Ap, AB, or a CO₃Ap–AB mixture. In vivo bone tissue and soft tissue evaluations were performed at specified time points. Additionally, in vitro experiments were conducted to assess the osteogenic differentiation of mesenchymal stem cells when exposed to the CO₃Ap–AB mixture.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In vivo experiments showed that the CO₃Ap–AB mixture significantly enhanced bone volume and maintained high bone mineral density compared to CO3Ap and AB alone. Furthermore, the mixture promoted longer epithelial attachment, suggesting its potential for long-term soft tissue stabilization. In vitro, the CO₃Ap–AB mixture effectively promoted osteogenic differentiation of mesenchymal stem cells.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The combination of CO₃Ap and AB exhibited a synergistic effect, enhancing early bone regeneration, osseointegration, and soft tissue sealing, which are crucial for implant stability. The CO₃Ap–AB mixture shows great potential as a clinically effective bone substitute for dental implant treatment in patients with compromised bone conditions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Influence of diameter and length on primary stability in various implant site densities—An in vitro study in polyurethane blocks","authors":"","doi":"10.1111/cid.70073","DOIUrl":"https://doi.org/10.1111/cid.70073","url":null,"abstract":"<p>\u0000 <b>RETRACTION</b>: <span>J. Gottlow</span>, <span>L. Sennerby</span>, “ <span>Influence of diameter and length on primary stability in various implant site densities—An in vitro study in polyurethane blocks</span>,” <i>Clinical Implant Dentistry and Related Research</i> <span>26</span>, no. <span>2</span> (<span>2024</span>): <span>327</span>–<span>332</span>, https://doi.org/10.1111/cid.13290.\u0000 </p><p>The above article, published online on November 5, 2023, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by mutual agreement of the authors, Johan Gottlow, DDS, and Lars Sennerby, DDS, PhD; the journal's Editor-in-Chief, Prof. Philippe Hujoel; Prof. Hom-Lay Wang; and Wiley Periodicals LLC. This retraction has been issued due to the identification of unattributed overlap between this article and an unpublished study conducted by a former colleague of the authors during their student years. This finding was confirmed by an institutional investigation. Accordingly, the article has been retracted to maintain the integrity of the scientific record.</p>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144519866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study on the Accuracy of Implant Placement Using 3D-Printed and Milled Guides Without Metal Sleeves","authors":"Juan Ballesteros,&nbsp;Solange Vásquez,&nbsp;Marta Revilla-León,&nbsp;Miguel Gómez-Polo","doi":"10.1111/cid.70072","DOIUrl":"https://doi.org/10.1111/cid.70072","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The present study aims to evaluate whether differences in accuracy of the implant positions exist for static computer-aided implant placement based on the manufacturing process of surgical guides and the inclusion or not of metal sleeves.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Seventy-two implants (6 per model) were placed in 12 models simulating a partially edentulous maxilla using 12 dentally supported surgical guides anchored with 2 anchor pins. The surgical guides were divided into three groups: additive manufactured with a metal sleeve (Group PS), additive manufactured without a metal sleeve (Group PNS), and subtractive manufactured without a metal sleeve (Group MNS). The internal drilling diameter was standardized for all groups (4.85 mm). Deviations between the planned virtual implant positions and the scanned postoperative models were assessed in three parameters: 3D deviations at the crest, 3D deviations at the apex, and angular deviations in the implant insertion axis. The Shapiro–Wilk test was applied to analyze the normality of the sample distribution. Kruskal–Wallis and Mann–Whitney tests were used to analyze the deviations among the groups (&lt;i&gt;α&lt;/i&gt; = 0.05).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Statistical differences were reported among the groups in the parameters: 3D deviations at the crest, 3D deviations at the apex, and angular deviations in the implant insertion axis (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). At the crest, the smallest 3D deviation was recorded in the MNS group (0.498 ± 0.337 mm) followed by the PNS group (0.660 ± 0.572 mm) and the PS group (1.028 ± 0.424 mm) (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). At the apex, as well, the lowest deviation was observed in the MNS group (0.810 ± 0.544 mm) followed by the PNS group (0.840 ± 0.620) and the PS group (1.360 ± 0.990 mm) (&lt;i&gt;p&lt;/i&gt; &lt; 0.05). Regarding angular deviations, the best results were obtained by the PNS group (1.44° ± 1.57°) with statistically significant differences with both the MNS group (2.90° ± 2.35°) and the PS group (3.88° ± 2.85°) (&lt;i&gt;p&lt;/i&gt; &lt; 0.05).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The accuracy of the implant position was affected by the inclusion or absence of metal sleeves and the manufacturing method. Overall, non-sleeved guides deliver better accuracy by reducing crestal and apical deviations, as well as angular errors. Differences between the groups without metal sleeves, 3D printed and milled, were found in the implant angulation, where the 3D printed group obtained more accurate results.&lt;/p&gt;\u0000 &lt;/s","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 4","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70072","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144503140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting Implant Failure and Complications Using Cluster Analysis After Variable Selection: A Retrospective Study","authors":"Jinlin Zhang,&nbsp;Yufeng Gao,&nbsp;Yannan Cao,&nbsp;Zhuang Ding,&nbsp;Bo Chen,&nbsp;Fangyong Zhu","doi":"10.1111/cid.70063","DOIUrl":"https://doi.org/10.1111/cid.70063","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Uneven data distribution (due to rare outcomes) and repeated measurements (from multiple implants per patient) hinder the creation of a precise oral implant failure risk model.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The aim of this study was to explore variable selection methods suitable for oral implant data, assess risk factors of early failure and postoperative complications, and apply the two-step cluster analysis to establish a risk prediction model for oral implant failure, providing a reference for clinical practice.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Materials and Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This study was a retrospective analysis, with early failure and postoperative complications serving as the outcome indicators. Given the repeated measurements and uneven distribution in oral implant data, our study conducted a comparative analysis between GEE and GEE with Firth penalization. This study evaluated the influencing factors screened by a more suitable model and utilized them for subsequent risk prediction. A two-step cluster analysis was applied to identify different subgroups of early failure and postoperative complications; their clinical characteristics were compared, and relevant risk prediction models were developed.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Among a total of 677 patients and 1200 implants, 21 implants were lost prior to loading, and postoperative complications occurred in 74 patients involving 94 implants. The GEE model with Firth's penalty term indicated that non-submerged healing (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), shorter implant length (&lt;i&gt;p&lt;/i&gt; &lt; 0.001), and thinner diameter (&lt;i&gt;p&lt;/i&gt; = 0.007) were risk factors for early failure. The GEE model showed that non-submerged healing (&lt;i&gt;p&lt;/i&gt; = 0.039) was a protective factor against postoperative complications, whereas unhealed extraction sockets at the implant site (&lt;i&gt;p&lt;/i&gt; = 0.048), the use of bone substitutes (&lt;i&gt;p&lt;/i&gt; = 0.008), and a history of periodontal disease (&lt;i&gt;p&lt;/i&gt; = 0.009) were risk factors. Additionally, the use of bovine tendon-derived absorbable biomembranes (&lt;i&gt;p&lt;/i&gt; = 0.036) may elevate the risk of postoperative complications. The two-step cluster analysis identified two patient subgroups, categorized as high-risk and low-risk, and the prediction model demonstrated good discrimination ability.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Early failure data were highly imbalanced, and the incorporation of the Firth penalty term provided significant benefits. However, its effectiveness in managing postoperative complication dat","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144367314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 6-Year Randomized Controlled Trial on Different Implant Designs in Maxillary Overdenture Patients","authors":"Stefan Matthijs,&nbsp;Véronique Christiaens,&nbsp;Carine Matthys,&nbsp;Hugo De Bruyn,&nbsp;Maarten Glibert","doi":"10.1111/cid.70069","DOIUrl":"https://doi.org/10.1111/cid.70069","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Background&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In order to reduce crestal bone remodeling around the implant shoulder, different implant macrodesigns have been developed. The presence of microthreads at the coronal part of the implant, as well as platform-shifting using a conical internal abutment connection, is suggested to limit bone remodeling. However, long-term studies excluding confounding factors to confirm this are scarce.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Aim&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This randomized controlled trial aimed to assess the effect of implant neck design (microthreaded vs. non-microthreaded) as well as type of abutment connection (internal conical vs. external flat-to-flat) on long-term crestal bone remodeling and peri-implant health. Additionally, the clinical outcome of bar-retained maxillary overdentures on 4 implants is reported after at least 6 years of function.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Materials and Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Twenty-five patients were treated with a bar-retained maxillary overdenture. Each patient received 4 different implants, one of each of the 4 experimental designs, with respectively: internal connection and microthreads on the implant neck (I MT); internal connection without microthreads (I NMT); external connection with microthreads (E MT); and external connection without microthreads (E NMT). Other features, such as diameter, surface topography, extent of platform switch, as well as the surgical and prosthetic treatment protocol, were identical. The implants were randomly allocated to the sites (posterior right, anterior right, anterior left, and posterior left), based on a pre-randomized, fixed-order assignment generated by a randomization software. Radiographic crestal bone loss (CBL), plaque score (PS), bleeding on probing (BoP) and probing pocket depth (PPD) were determined after 1 and 6 function years.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Two implants in 2 patients were excluded because of protocol deviations, requiring the placement of a wider implant. Four out of 98 implants (4.1%) failed during the provisionalization process. These were replaced with the same type of implant after 3 months of healing and were included in further analysis. Due to the relatively small sample size and high drop-out rate, the effect of microthread design and connection on implant survival could only be reported descriptively. Twenty patients could be re-evaluated at the 1-year and 6-year time points, resulting in 78 examined implants. These showed a mean CBL of 0.39 mm (SD: 0.68; range: 0–3.42) after 1 year and 0.37 mm (SD: 0.61; range: −0.34—3.03) after 6 years. Between the 4 different study implants, no statisticall","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144367315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Free Gingival Graft Around Implants in Reconstructed Mandibles With Free Fibula Flaps or Iliac Bone Flaps","authors":"Jianfeng Liufu,&nbsp;Yanjun Ge,&nbsp;Xiancheng Zeng,&nbsp;Jiayun Dong,&nbsp;Yifan Kang,&nbsp;Yuru Hu,&nbsp;Ruifang Lu,&nbsp;Xiaofeng Shan,&nbsp;Zhigang Cai","doi":"10.1111/cid.70070","DOIUrl":"https://doi.org/10.1111/cid.70070","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To compare the efficacy of free gingival graft (FGG) around implants in reconstructed mandibles with free fibula flaps (FFFs) or iliac bone flaps (IBFs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>We included patients receiving mandibular reconstruction with FFFs or IBFs due to the removal of maxillofacial tumors who underwent implant and FGG placement prior to restoration. Clinical data were evaluated before (T0), immediately after (T1), 3 months after (T2), 6 months after (T3) and 1 year after (T4) FGG placement. We analyzed the keratinized mucosa width (KMW) gain and the shrinkage rate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 30 patients were enrolled in this study, including 15 patients with 48 implants in the FFFs group and 15 patients with 52 implants in the IBFs group. The buccal KMW gain and shrinkage rate in the FFFs group were not statistically significant compared with the IBFs group at T4. In the IBFs group, the buccal KMW gain and shrinkage rate remained relatively stable after 6 months. The lingual KMW gain in the FFFs group was significantly greater than that in the IBFs group at T4 (2.1 ± 0.2 mm vs. 1.5 ± 0.2 mm, <i>p</i> &lt; 0.05). The lingual shrinkage rate in the FFFs group was significantly smaller than that in the IBFs group at T4 (27.8% ± 5.5% vs. 47.3% ± 5.5%, <i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>FGG can reconstruct the keratinized mucosa effectively in a reconstructed mandible. The keratinized mucosa width gain decreases over time.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144367327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full-Zirconia Single Molar Implant-Supported Restorations With Angulated Screw Channel Abutments: 5-Year Results of a Prospective Case Series Study","authors":"Jantien H. W. de Beus,&nbsp;Henny J. A. Meijer,&nbsp;Christiaan W. P. Pol,&nbsp;Ulf Schepke,&nbsp;Gerry M. Raghoebar,&nbsp;Marco S. Cune","doi":"10.1111/cid.70068","DOIUrl":"https://doi.org/10.1111/cid.70068","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Full-zirconia (ZrO₂) restorations were introduced to address the most common complications in implant-supported restorations in the posterior region: fractures of the veneering. The aim of this prospective case series study was to evaluate full-ZrO₂ implant-supported restorations with angulated screw channel abutments (ASCs) in the molar region of the maxilla and mandible and their effect on hard and soft peri-implant tissues, and patient-related outcome measures (PROMs), during a 5-year follow-up period.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Material and Methods</h3>\u0000 \u0000 <p>Patients with a single missing molar in the maxilla or mandible with sufficient bone volume and an implant site free of infection were included. Thirty consecutive patients received a parallel-walled implant with conical connection. After 3 months, a full contour screw-retained ZrO₂ restoration with an ASC was fabricated and connected to the implant. Clinical and radiographic examinations were performed 1 month, 12 months, and 5 years after placement of the restoration. Implant success probability was calculated using Kaplan–Meier statistics, and confidence intervals were given over the results at 5 years. Patient-reported outcome measures (PROMs) were scored prior to treatment and at follow-up intervals. The primary outcome measure was the success of the restoration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All patients could be evaluated after 5 years. Success probability at 5 years was 73.0% (95% CI [57.0%; 89.0%]). Implant survival was 100% and restoration survival was 97%. The encountered technical complications were easily repairable (<i>n</i> = 12). From loading to the 5-years follow-up, the mean marginal bone loss was 0.30 mm (SD 0.52 mm). Mean scores for plaque, calculus, peri-implant mucosa, bleeding, and pocket probing depth were low, depicting healthy peri-implant conditions. PROMs had significantly improved, and the mean overall score was 9.1 ± 0.7 (scale 1–10).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Full-ZrO₂ implant-supported restorations with ASC abutments employed in this study, when applied in maxillary and mandibular posterior regions, show a 97% survival rate. However, a high incidence rate of technical complications (<i>n</i> = 12) was noted during the 5-year observation period.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144300394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consequence of Bisphosphonate Use on Dental Implant Removal in Osteoporotic Patient: A Nationwide Cohort Study","authors":"Jung-Hyun Park,&nbsp;Heon-Young Kim,&nbsp;Jae-Ryun Lee,&nbsp;Hyo-Jung Lee,&nbsp;Jin-Woo Kim","doi":"10.1111/cid.70062","DOIUrl":"https://doi.org/10.1111/cid.70062","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>This nationwide population-based cohort study aimed to investigate the relationship between bisphosphonate (BP) use and dental implant removal in patients with osteoporosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 389 226 individuals aged ≥ 65 years with osteoporosis who underwent dental implant surgery between 2014 and 2018 were included. Patients were classified into BP and control groups based on their prescription records. Implant removal was identified using the procedural codes from 2019 to 2020. Multivariate logistic regression analysis was performed to examine the association between BP and implant removal. Subgroup analyses evaluated the impact of the BP administration route (oral vs. intravenous), BP type, and cumulative defined daily dose (DDD) on the risk of implant removal.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The BP group demonstrated a modestly increased risk of implant removal compared to the control group (adjusted odds ratio [OR]: 1.09; 95% confidence interval [CI]: 1.05–1.15). Participants with periodontitis had a significantly higher risk of implant removal than participants without periodontitis (adjusted OR: 1.87; 95% CI: 1.63–2.15). Among BP users, the subgroup analysis revealed that intravenous BP administration was associated with a lower risk of implant removal than oral administration (adjusted OR: 0.87; 95% CI: 0.80–0.94). In addition, the risk of implant removal increased progressively with higher cumulative DDDs, highlighting the importance of total BP exposure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study underscores the critical role of cumulative BP exposure in the risk of implant removal, which challenges conventional assumptions regarding administration routes. Future research should explore strategies to optimize implant outcomes in patients with osteoporosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144256352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Marginal Bone Changes Around Tissue-Level Implants After Prosthesis Delivery: A Multicenter Prospective Study","authors":"Sergio Spinato,&nbsp;Fabio Bernardello,&nbsp;Claudio Stacchi,&nbsp;Carlo Maria Soardi,&nbsp;Marcello Messina,&nbsp;Antonio Rapani,&nbsp;Teresa Lombardi","doi":"10.1111/cid.70071","DOIUrl":"https://doi.org/10.1111/cid.70071","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Early marginal bone loss (EMBL) is a non-infective phenomenon occurring around the implant neck from placement to the first year of prosthetic function, being influenced by both surgical and prosthetic factors. This multi-center prospective study assesses the impact of different variables potentially influencing marginal bone stability during the period from crown delivery to 18 months of functional loading.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Forty-seven patients requiring a single posterior mandibular implant were selected according to specific criteria. Tissue-level implants were placed at different crestal bone levels based on vertical mucosal thickness and followed in an unsubmerged healing protocol, as described in a previous study evaluating peri-implant bone levels (PBL) from implant placement (T0) to crown delivery (T1). The present study continues this evaluation, focusing on MBL from T1 to 18 months post-loading (T2). Host-related factors (age, gender, smoking, history of periodontitis, vertical mucosal thickness) and specific prosthetic parameters, including crown mesio-distal dimension, emergence angle, and transmucosal collar height were recorded. Multiple linear regression analysis explored associations between MBL and prosthetic or patient-related factors, with significance set at <i>p</i> &lt; 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Marginal bone levels remained stable from T1 to T2, with no significant association between MBL and host-related factors or defined prosthetic variables. However, total MBL from T0 to T2 was significantly higher around implants with thin mucosa at T0 compared to medium and thick mucosa. Multivariate analysis (T0-T2) identified thin mucosa and smoking as significant MBL predictors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>From T1 to T2, marginal bone levels around tissue-level implants remain stable, with no significant influence from variables analyzed. Conversely, peri-implant bone resorption between T0 and T2 is significantly associated with thin mucosa (primarily affecting T0-T1) and smoking.</p>\u0000 \u0000 <p><b>Trial Registration:</b> www.clinicaltrials.gov: NCT05363306</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"27 3","pages":""},"PeriodicalIF":3.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.70071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144264530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}