Cognitive Affective & Behavioral Neuroscience最新文献_第9页

Leveraging a cross-species probabilistic reward task (PRT) in suicide research. A commentary on Luc and Kangas (2024). 在自杀研究中利用跨物种概率奖励任务（PRT）。对 Luc 和 Kangas（2024 年）的评论。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-04-01 Epub Date: 2024-03-12 DOI: 10.3758/s13415-024-01181-0

Steven J Lamontagne, Carlos A Zarate, Elizabeth D Ballard

引用次数: 0

Improving preclinical to clinical translation of cognitive function for aging-related disorders: the utility of comprehensive touchscreen testing batteries in common marmosets. 改善认知功能从临床前到临床的转化，治疗与衰老相关的疾病：普通狨猴综合触摸屏测试电池的效用。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-04-01 Epub Date: 2024-01-10 DOI: 10.3758/s13415-023-01144-x

Takeshi Murai, Lauren Bailey, Laura Schultz, Lauren Mongeau, Andrew DeSana, Afonso C Silva, Angela C Roberts, Stacey J Sukoff Rizzo

{"title":"Improving preclinical to clinical translation of cognitive function for aging-related disorders: the utility of comprehensive touchscreen testing batteries in common marmosets.","authors":"Takeshi Murai, Lauren Bailey, Laura Schultz, Lauren Mongeau, Andrew DeSana, Afonso C Silva, Angela C Roberts, Stacey J Sukoff Rizzo","doi":"10.3758/s13415-023-01144-x","DOIUrl":"10.3758/s13415-023-01144-x","url":null,"abstract":"Concerns about poor animal to human translation have come increasingly to the fore, in particular with regards to cognitive improvements in rodent models, which have failed to translate to meaningful clinical benefit in humans. This problem has been widely acknowledged, most recently in the field of Alzheimer's disease, although this issue pervades the spectrum of central nervous system (CNS) disorders, including neurodevelopmental, neuropsychiatric, and neurodegenerative diseases. Consequently, recent efforts have focused on improving preclinical to clinical translation by incorporating more clinically analogous outcome measures of cognition, such as touchscreen-based assays, which can be employed across species, and have great potential to minimize the translational gap. For aging-related research, it also is important to incorporate model systems that facilitate the study of the long prodromal phase in which cognitive decline begins to emerge and which is a major limitation of short-lived species, such as laboratory rodents. We posit that to improve translation of cognitive function and dysfunction, nonhuman primate models, which have conserved anatomical and functional organization of the primate brain, are necessary to move the field of translational research forward and to bridge the translational gaps. The present studies describe the establishment of a comprehensive battery of touchscreen-based tasks that capture a spectrum of domains sensitive to detecting aging-related cognitive decline, which will provide the greatest benefit through longitudinal evaluation throughout the prolonged lifespan of the marmoset.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11039501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139418484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rodent tests of depression and anxiety: Construct validity and translational relevance. 抑郁和焦虑的啮齿动物测试：结构有效性和转化相关性。

IF 2.9 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-04-01 Epub Date: 2024-02-27 DOI: 10.3758/s13415-024-01171-2

Sinem Gencturk, Gunes Unal

{"title":"Rodent tests of depression and anxiety: Construct validity and translational relevance.","authors":"Sinem Gencturk, Gunes Unal","doi":"10.3758/s13415-024-01171-2","DOIUrl":"10.3758/s13415-024-01171-2","url":null,"abstract":"Behavioral testing constitutes the primary method to measure the emotional states of nonhuman animals in preclinical research. Emerging as the characteristic tool of the behaviorist school of psychology, behavioral testing of animals, particularly rodents, is employed to understand the complex cognitive and affective symptoms of neuropsychiatric disorders. Following the symptom-based diagnosis model of the DSM, rodent models and tests of depression and anxiety focus on behavioral patterns that resemble the superficial symptoms of these disorders. While these practices provided researchers with a platform to screen novel antidepressant and anxiolytic drug candidates, their construct validity-involving relevant underlying mechanisms-has been questioned. In this review, we present the laboratory procedures used to assess depressive- and anxiety-like behaviors in rats and mice. These include constructs that rely on stress-triggered responses, such as behavioral despair, and those that emerge with nonaversive training, such as cognitive bias. We describe the specific behavioral tests that are used to assess these constructs and discuss the criticisms on their theoretical background. We review specific concerns about the construct validity and translational relevance of individual behavioral tests, outline the limitations of the traditional, symptom-based interpretation, and introduce novel, ethologically relevant frameworks that emphasize simple behavioral patterns. Finally, we explore behavioral monitoring and morphological analysis methods that can be integrated into behavioral testing and discuss how they can enhance the construct validity of these tests.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11039509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139984400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A translational approach to understanding anxiety: the limitations, strengths of differences. A commentary on Drzewiecki & Fox (2024). 理解焦虑的转化方法：差异的局限性和优势。对 Drzewiecki & Fox (2024) 的评论。

IF 2.9 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-04-01 Epub Date: 2024-03-19 DOI: 10.3758/s13415-024-01182-z

Felippe Espinelli Amorim, Morgane Colom, Amy L Milton

引用次数: 0

Texture congruence modulates perceptual bias but not sensitivity to visuotactile stimulation during the rubber hand illusion. 质地一致会调节感知偏差，但不会调节橡胶手幻觉中视觉触觉刺激的敏感性。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-02-01 Epub Date: 2024-01-23 DOI: 10.3758/s13415-024-01155-2

Renzo C Lanfranco, Marie Chancel, H Henrik Ehrsson

{"title":"Texture congruence modulates perceptual bias but not sensitivity to visuotactile stimulation during the rubber hand illusion.","authors":"Renzo C Lanfranco, Marie Chancel, H Henrik Ehrsson","doi":"10.3758/s13415-024-01155-2","DOIUrl":"10.3758/s13415-024-01155-2","url":null,"abstract":"The sense of body ownership is the feeling that one's body belongs to oneself. To study body ownership, researchers use bodily illusions, such as the rubber hand illusion (RHI), which involves experiencing a visible rubber hand as part of one's body when the rubber hand is stroked simultaneously with the hidden real hand. The RHI is based on a combination of vision, touch, and proprioceptive information following the principles of multisensory integration. It has been posited that texture incongruence between rubber hand and real hand weakens the RHI, but the underlying mechanisms remain poorly understood. To investigate this, we recently developed a novel psychophysical RHI paradigm. Based on fitting psychometric functions, we discovered the RHI resulted in shifts in the point of subjective equality when the rubber hand and the real hand were stroked with matching materials. We analysed these datasets further by using signal detection theory analysis, which distinguishes between the participants' sensitivity to visuotactile stimulation and the associated perceptual bias. We found that texture incongruence influences the RHI's perceptual bias but not its sensitivity to visuotactile stimulation. We observed that the texture congruence bias effect was the strongest in shorter visuotactile asynchronies (50-100 ms) and weaker in longer asynchronies (200 ms). These results suggest texture-related perceptual bias is most prominent when the illusion's sensitivity is at its lowest. Our findings shed light on the intricate interactions between top-down and bottom-up processes in body ownership, the links between body ownership and multisensory integration, and the impact of texture congruence on the RHI.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lateralization of self-control over the dorsolateral prefrontal cortex in decision-making: a systematic review and meta-analytic evidence from noninvasive brain stimulation. 决策中前额叶皮层背外侧自我控制的侧化：非侵入性脑部刺激的系统回顾和元分析证据。

IF 2.9 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-02-01 Epub Date: 2024-01-11 DOI: 10.3758/s13415-023-01148-7

Yongle Lin, Tingyong Feng

{"title":"Lateralization of self-control over the dorsolateral prefrontal cortex in decision-making: a systematic review and meta-analytic evidence from noninvasive brain stimulation.","authors":"Yongle Lin, Tingyong Feng","doi":"10.3758/s13415-023-01148-7","DOIUrl":"10.3758/s13415-023-01148-7","url":null,"abstract":"The dorsolateral prefrontal cortex (DLPFC) has been widely recognized as a crucial brain \"control area.\" Recently, its causal role in promoting deliberate decision-making through self-control and the asymmetric performance of the left and right DLPFC in control functions have attracted the interest of many researchers. This study was designed to investigate the role of DLPFC in decision-making behaviors and lateralization of its control function by systematically examining the effects of noninvasive brain stimulation (NIBS) over the DLPFC on intertemporal choice, risk decision-making, and social fairness-related decision-making tasks. Literature searches were implemented at PubMed, Embase, Cochrane, Web of Science, Wanfang Data, China Science and Technology Journal Database, and China National Knowledge Infrastructure until May 10, 2022. Meta-analytic results for included studies were estimated by random-effect models. A total of 33 eligible studies were identified, yielding 130 effect sizes. Our results indicated that compared to sham group, excitatory NIBS over the left DLPFC reduced delay discounting rate (standardized mean differences, SMD = -0.51; 95% confidence interval, 95% CI: [-0.81, -0.21]) and risk-taking performance (SMD = -0.39, 95% CI [-0.68, -0.10]), and inhibitory NIBS over the right DLPFC increased self-interested choice of unfair offers (SMD = 0.50, 95% CI [0.04, 0.97]). Finding of current work indicated that neural excitement of the DLPFC activation improve individuals' self-control during decision-makings, whereas neural inhibition results in impaired control. In addition, our analyses furnish causal evidence for the presence of functional lateralization in the left and right DLPFC in monetary impulsive decision-making and social decision-making, respectively.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain representations of space and time in episodic memory: A systematic review and meta-analysis. 情景记忆中空间和时间的大脑表征:系统回顾和荟萃分析。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-02-01 Epub Date: 2023-11-29 DOI: 10.3758/s13415-023-01140-1

César Torres-Morales, Selene Cansino

{"title":"Brain representations of space and time in episodic memory: A systematic review and meta-analysis.","authors":"César Torres-Morales, Selene Cansino","doi":"10.3758/s13415-023-01140-1","DOIUrl":"10.3758/s13415-023-01140-1","url":null,"abstract":"All experiences preserved within episodic memory contain information on the space and time of events. The hippocampus is the main brain region involved in processing spatial and temporal information for incorporation within episodic memory representations. However, the other brain regions involved in the encoding and retrieval of spatial and temporal information within episodic memory are unclear, because a systematic review of related studies is lacking and the findings are scattered. The present study was designed to integrate the results of functional magnetic resonance imaging and positron emission tomography studies by means of a systematic review and meta-analysis to provide converging evidence. In particular, we focused on identifying the brain regions involved in the retrieval of spatial and temporal information. We identified a spatial retrieval network consisting of the inferior temporal gyrus, parahippocampal gyrus, superior parietal lobule, angular gyrus, and precuneus. Temporal context retrieval was supported by the dorsolateral prefrontal cortex. Thus, the retrieval of spatial and temporal information is supported by different brain regions, highlighting their different natures within episodic memory.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827973/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Theory of mind in mild cognitive impairment and Parkinson's disease: The role of memory impairment. 轻度认知障碍和帕金森病的心理理论:记忆障碍的作用。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-02-01 Epub Date: 2023-12-04 DOI: 10.3758/s13415-023-01142-z

Gianpaolo Maggi, Chiara Giacobbe, Carmine Vitale, Marianna Amboni, Ignacio Obeso, Gabriella Santangelo

{"title":"Theory of mind in mild cognitive impairment and Parkinson's disease: The role of memory impairment.","authors":"Gianpaolo Maggi, Chiara Giacobbe, Carmine Vitale, Marianna Amboni, Ignacio Obeso, Gabriella Santangelo","doi":"10.3758/s13415-023-01142-z","DOIUrl":"10.3758/s13415-023-01142-z","url":null,"abstract":"Background: Social cognition is impaired in Parkinson's disease (PD). Whether social cognitive impairment (iSC) is a by-product of the underlying cognitive deficits in PD or a process independent of cognitive status is unknown. To this end, the present study was designed to investigate the weight of specific cognitive deficits in social cognition, considering different mild cognitive impairment subtypes of PD (PD-MCI).Methods: Fifty-eight PD patients underwent a neuropsychological battery assessing executive functions, memory, language, and visuospatial domains, together with social cognitive tests focused on theory of mind (ToM). Patients were divided into subgroups according to their clinical cognitive status: amnestic PD-MCI (PD-aMCI, n = 18), non-amnestic PD-MCI (PD-naMCI, n = 16), and cognitively unimpaired (PD-CU, n = 24). Composite scores for cognitive and social domains were computed to perform mediation analyses.Results: Memory and language impairments mediated the effect of executive functioning in social cognitive deficits in PD patients. Dividing by MCI subgroups, iSC occurred more frequently in PD-aMCI (77.8%) than in PD-naMCI (18.8%) and PD-CU (8.3%). Moreover, PD-aMCI performed worse than PD-CU in all social cognitive measures, whereas PD-naMCI performed worse than PD-CU in only one subtype of the affective and cognitive ToM tests.Conclusions: Our findings suggest that ToM impairment in PD can be explained by memory dysfunction that mediates executive control. ToM downsides in the amnesic forms of PD-MCI may suggest that subtle changes in social cognition could partly explain future transitions into dementia. Hence, the evaluation of social cognition in PD is critical to characterize a possible behavioral marker of cognitive decline.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138483371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Affective valence does not reflect progress prediction errors in perceptual decisions. 情感价位并不反映知觉决策中的进度预测误差。

IF 2.9 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-02-01 Epub Date: 2024-01-05 DOI: 10.3758/s13415-023-01147-8

Alan Voodla, Andero Uusberg, Kobe Desender

{"title":"Affective valence does not reflect progress prediction errors in perceptual decisions.","authors":"Alan Voodla, Andero Uusberg, Kobe Desender","doi":"10.3758/s13415-023-01147-8","DOIUrl":"10.3758/s13415-023-01147-8","url":null,"abstract":"Affective valence and intensity form the core of our emotional experiences. It has been proposed that affect reflects the prediction error between expected and actual states, such that better/worse-than-expected discrepancies result in positive/negative affect. However, whether the same principle applies to progress prediction errors remains unclear. We empirically and computationally evaluate the hypothesis that affect reflects the difference between expected and actual progress in forming a perceptual decision. We model affect within an evidence accumulation framework where actual progress is mapped onto the drift-rate parameter and expected progress onto an expected drift-rate parameter. Affect is computed as the difference between the expected and actual amount of accumulated evidence. We find that expected and actual progress both influence affect, but in an additive manner that does not align with a prediction error account. Our computational model reproduces both task behavior and affective ratings, suggesting that sequential sampling models provide a promising framework to model progress appraisals. These results show that although affect is sensitive to both expected and actual progress, it does not reflect the computation of a progress prediction error.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139106883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of task context on EEG correlates of mind-wandering. 任务情境对走神相关脑电图的影响。

IF 2.5 3区医学

Cognitive Affective & Behavioral Neuroscience Pub Date : 2024-02-01 Epub Date: 2023-11-29 DOI: 10.3758/s13415-023-01138-9

Rebecca J Compton, Danylo Shudrenko, Katelyn Mann, Emil Turdukulov, Erin Ng, Lucas Miller

{"title":"Effects of task context on EEG correlates of mind-wandering.","authors":"Rebecca J Compton, Danylo Shudrenko, Katelyn Mann, Emil Turdukulov, Erin Ng, Lucas Miller","doi":"10.3758/s13415-023-01138-9","DOIUrl":"10.3758/s13415-023-01138-9","url":null,"abstract":"This study was designed to examine how mind-wandering and its neural correlates vary across tasks with different attentional demands, motivated by the context regulation hypothesis of mind-wandering. Participants (n = 59 undergraduates) completed the sustained attention to response task (SART) and the Stroop selective attention task in counterbalanced order while EEG was recorded. The tasks included experience-sampling probes to identify self-reported episodes of mind-wandering, along with retrospective reports. Participants reported more mind-wandering during the SART than the Stroop and during whichever task was presented second during the session, compared with first. Replicating previous findings, EEG data (n = 37 usable participants) indicated increased alpha oscillations during episodes of mind-wandering, compared with on-task episodes, for both the SART and Stroop tasks. ERP data, focused on the P2 component reflecting perceptual processing, found that mind-wandering was associated with increased P2 amplitudes during the Stroop task, counter to predictions from the perceptual decoupling theory. Overall, the study found that self-report and neural correlates of mind-wandering are sensitive to task context. This line of research can further the understanding of how mechanisms of mind-wandering are adapted to varied tasks and situations.","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138464143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0