{"title":"Distortion of overlapping memories relates to arousal and anxiety.","authors":"Erin Morrow, David Clewett","doi":"10.3758/s13415-024-01229-1","DOIUrl":"10.3758/s13415-024-01229-1","url":null,"abstract":"<p><p>Everyday experiences often overlap, challenging our ability to maintain distinct episodic memories. One way to resolve such interference is by exaggerating subtle differences between remembered events, a phenomenon known as memory repulsion. Here, we tested whether repulsion is influenced by emotional arousal, when resolving memory interference is perhaps most needed. We adapted an existing paradigm in which participants repeatedly studied object-face associations. Participants studied two different-colored versions of each object: a to-be-tested \"target\" and its not-to-be-tested \"competitor\" pair mate. The level of interference between target and competitor pair mates was manipulated by making the object colors either highly similar or less similar, depending on the participant group. To manipulate arousal, the competitor object-face associations were preceded by either a neutral tone or an aversive and arousing burst of white noise. Memory distortion for the color of the target objects was tested after each study round to examine whether memory distortions emerge after learning. We found that participants with greater sound-induced pupil dilations, an index of physiological arousal, showed greater memory attraction of target colors towards highly similar competitor colors. Greater memory attraction was also correlated with greater memory interference in the last round of learning. Additionally, individuals who self-reported higher trait anxiety showed greater memory attraction when one of the overlapping memories was associated with something aversive. Our findings suggest that memories of similar neutral and arousing events may blur together after repeated exposures, especially in individuals who show higher arousal responses and symptoms of anxiety.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"154-172"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of spatial processing in verbal serial order working memory.","authors":"Yingxue Tian, Simon Fischer-Baum","doi":"10.3758/s13415-024-01240-6","DOIUrl":"10.3758/s13415-024-01240-6","url":null,"abstract":"<p><p>In a sequence, at least two aspects of information-the identity of items and their serial order-are maintained and supported by distinct working memory (WM) capacities. Verbal serial order WM is modulated by spatial processing, reflected in the Spatial Position Association of Response Codes (SPoARC) effect-the left-beginning, right-end positional association between space and serial position of verbal WM memoranda. We investigated the individual differences in this modulation with both behavioral and neurobiological approaches. We administered a battery of seven behavioral tasks with 160 healthy adults and collected resting-state fMRI data from a subset of 25 participants. With a multilevel mixed-effects modeling approach, we found that the SPoARC effect's magnitude predicts individual differences in verbal serial order WM capacity and is related to spatial item WM capacity. With a graph-theory-based analytic approach, this interaction between verbal serial order WM and spatial WM was corroborated in that the level of interaction between corresponding cortical regions (indexed by modularity) was predictive of the magnitude of the SPoARC effect. Additionally, the modularity of cortical regions associated with verbal serial order WM and spatial attention predicted the SPoARC effect's magnitude, indicating the involvement of spatial attention in this modulation. Together, our findings highlight multiple sources of the interplay between verbal serial order WM and spatial processing.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"210-239"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephanie E Rhoten, Michael J Wenger, Lisa A De Stefano
{"title":"Iron deficiency negatively affects behavioral measures of learning, indirect neural measures of dopamine, and neural efficiency.","authors":"Stephanie E Rhoten, Michael J Wenger, Lisa A De Stefano","doi":"10.3758/s13415-024-01241-5","DOIUrl":"10.3758/s13415-024-01241-5","url":null,"abstract":"<p><p>Iron deficiency (ID) is the most prevalent nutrient deficiency in the world, with a growing literature documenting the negative effects of ID on perception, attention, and memory. Animal models of ID suggest that dysregulation of dopamine is responsible for the deficits in memory. However, evidence that ID affects dopamine in humans is extremely limited. We report the results of a study involving college-aged women with and without ID learning two different category structures - a rule-based and an information-integration structure - selected based on the putative differential role of dopamine in learning these two structures. ID non-anemic (IDNA) and iron-sufficient (IS) women completed 1200 learning trials for each structure. EEG was collected to assess the effects of ID on features affected by dopaminergic state: error-related negativity (ERN) and positivity (Pe), feedback-related negativity (FRN), and task-related blink rate. In addition, we examined the EEG data for dynamics distinguishing IDNA from IS women, including a measure of neural efficiency. Both groups of women were able to learn both structures. However, IDNA women were initially slower and less accurate than IS women, specifically for the rule-based structure. There were large and persistent group differences in brain dynamics and neural efficiency measures. The results are discussed with respect to the selective impact of ID on initial rule-based learning and the persistent effect of ID on dopamine signaling and energetic efficiency.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"89-113"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhaoqi Zhang, Lieke L F van Lieshout, Olympia Colizoli, Haoqian Li, Tongxi Yang, Chao Liu, Shaozheng Qin, Harold Bekkering
{"title":"A cross-cultural comparison of intrinsic and extrinsic motivational drives for learning.","authors":"Zhaoqi Zhang, Lieke L F van Lieshout, Olympia Colizoli, Haoqian Li, Tongxi Yang, Chao Liu, Shaozheng Qin, Harold Bekkering","doi":"10.3758/s13415-024-01228-2","DOIUrl":"10.3758/s13415-024-01228-2","url":null,"abstract":"<p><p>Intrinsic motivational drives, like the autonomous feeling of control, and extrinsic motivational drives, like monetary reward, can benefit learning. Extensive research has focused on neurobiological and psychological factors that affect these drives, but our understanding of the sociocultural factors is limited. Here, we compared the effects of autonomy and rewards on episodic recognition memory between students from Dutch and Chinese universities. In an exploratory learning task, participants viewed partially obscured objects that they needed to subsequently remember. We independently manipulated autonomy, as volitional control over an exploration trajectory, as well as the chance to receive monetary rewards. The learning task was followed by memory tests for objects and locations. For both cultural groups, we found that participants learned better in autonomous than non-autonomous conditions. However, the beneficial effect of reward on memory performance was stronger for Chinese than for Dutch participants. By incorporating the sociocultural brain perspective, we discuss how differences in norms and values between Eastern and Western cultures can be integrated with the neurocognitive framework about dorsal lateral and ventral medial prefrontal cortex and dopaminergic reward modulations on learning and memory. These findings have important implications for understanding the neurocognitive mechanisms in which both autonomy and extrinsic rewards are commonly used to motivate students in the realm of education and urge more attention to investigate cultural differences in learning.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":"25-44"},"PeriodicalIF":2.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11805854/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction: Changes in the level of unitization moderate the impact of unitization on associative memory and its underlying processing.","authors":"Zejun Liu, Yajun Zhu, Xiuping Song","doi":"10.3758/s13415-025-01264-6","DOIUrl":"https://doi.org/10.3758/s13415-025-01264-6","url":null,"abstract":"","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kenneth W Carlson, Harry R Smolker, Louisa L Smith, Hannah R Snyder, Benjamin L Hankin, Marie T Banich
{"title":"Individual differences in intolerance of uncertainty is primarily linked to the structure of inferior frontal regions.","authors":"Kenneth W Carlson, Harry R Smolker, Louisa L Smith, Hannah R Snyder, Benjamin L Hankin, Marie T Banich","doi":"10.3758/s13415-024-01262-0","DOIUrl":"10.3758/s13415-024-01262-0","url":null,"abstract":"<p><p>Increased intolerance of uncertainty (IU), or distress felt when encountering situations with unknown outcomes, occurs transdiagnostically across various forms of psychopathology and is targeted in therapeutic intervention. Increased intolerance of uncertainty shows overlap with symptoms of internalizing disorders, such as depression and anxiety, including negative affect and anxious apprehension (worry). While neuroanatomical correlates of IU have been reported, previous investigations have not disentangled the specific neural substrates of IU above and beyond any overlapping relationships with aspects of internalizing psychopathology. The current study did so in a sample of 42 adults and 79 adolescents, who completed questionnaires assessing IU and internalizing symptoms, and underwent structural MRI. When controlling for internalizing symptoms, across adults and adolescents, specific associations of IU were found with the structure of the inferior frontal cortex and orbitofrontal cortex, regions implicated in cognitive control and emotional valuation/regulation. In addition, in adolescents, associations were observed with rostral middle frontal cortex and portions of the cingulate cortex. No associations were observed with threat-related regions, such as the amygdala. Potential cognitive/emotional mechanisms that might explain the association between individual differences in intolerance of uncertainty and morphology of the inferior frontal cortex are discussed.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mei Li, DengFang Tang, Wenbin Pan, Yujie Zhang, Jiachen Lu, Hong Li
{"title":"The influence of social status and promise levels in trust games: An Event-Related Potential (ERP) study.","authors":"Mei Li, DengFang Tang, Wenbin Pan, Yujie Zhang, Jiachen Lu, Hong Li","doi":"10.3758/s13415-024-01259-9","DOIUrl":"10.3758/s13415-024-01259-9","url":null,"abstract":"<p><p>Promises are widely used to increase trust in social status; yet how promise levels and social status influence trust behavior and its underlying neurophysiological mechanisms remain unclear. We used a modified trust game to investigate the effects of promise levels and social status on trust behavior. Participants, as investors paired with trustees of varying social status who were given the opportunity to promise to return different levels of money, were required to decide to whether trust the trustees. In Experiment 1, trustees promised to return high-, medium-, or low-level money to participants, and no return feedback was provided. In Experiment 2, trustees promised to return high- and low-level money to participants. Return feedback was provided and event-related potential (ERP) data were recorded. The behavioral results indicated that participants trusted high-status partners more than low-status partners, regardless of the promise level. The ERP results showed that with low-status partners, the N2 was more negative and the P3 was smaller under low-level promise conditions than under high-level promise conditions. However, with high-status partner, there were no differences in N2 and P3 between high- and low-level promise conditions. Our findings suggest that social status may affect the perception of potential risks across different promise levels in trust.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Attentional Inhibition Ability Predicts Neural Representation During Challenging Auditory Streaming.","authors":"Joan Belo, Maureen Clerc, Daniele Schon","doi":"10.3758/s13415-024-01260-2","DOIUrl":"https://doi.org/10.3758/s13415-024-01260-2","url":null,"abstract":"<p><p>Focusing on a single source within a complex auditory scene is challenging. M/EEG-based auditory attention detection (AAD) allows to detect which stream an individual is attending to within a set of multiple concurrent streams. The high interindividual variability in the auditory attention detection performance often is attributed to physiological factors and signal-to-noise ratio of neural data. We hypothesize that executive functions-in particular sustained attention, working memory, and attentional inhibition-may partly explain the variability in auditory attention detection performance, because they support the cognitive processes required when listening to complex auditory scenes. We chose a particularly challenging auditory scene by presenting dichotically polyphonic classical piano excerpts that lasted 1 min each. Two different excerpts were presented simultaneously, one in each ear. Forty-one participants, with different degrees of musical expertise, listened to these complex auditory scenes focusing on one ear while we recorded the EEG. Participants also completed several tasks assessing executive functions. As expected, EEG-based auditory attention detection was greater for attended than unattended stimuli. Importantly, attentional inhibition ability did explain 6% of the reconstruction accuracy and 8% of the classification accuracy. No other executive function was a significant predictor of reconstruction or classification accuracies. No clear effect of musical expertise was found on reconstruction and classification performance. In conclusion, cognitive factors seem to impact the robustness of the neural auditory representation and hence the performance of EEG-based decoding approaches. Taking advantage of this relation could be useful to improve next-generation hearing aids.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Stochastic decisions support optimal foraging of volatile environments, and are disrupted by anxiety.","authors":"Alex Lloyd, Ryan McKay, Nicholas Furl","doi":"10.3758/s13415-024-01256-y","DOIUrl":"https://doi.org/10.3758/s13415-024-01256-y","url":null,"abstract":"<p><p>Adolescence is a developmental period of relative volatility, where the individual experiences significant changes to their physical and social environment. The ability to adapt to the volatility of one's surroundings is an important cognitive ability, particularly while foraging, a near-ubiquitous behaviour across the animal kingdom. As adolescents experience more volatility in their surroundings, we predicted that this age group would be more adept than adults at using exploration to adjust to volatility. We employed a foraging task with a well-validated computational model to characterise the mechanisms of exploration in volatile environments, preregistering the hypothesis that adolescents (aged 16-17; N = 91) would exhibit more optimal adaptation of their learning rate to changes in environmental volatility compared with adults (aged 24+; N = 90). However, surprisingly, both adolescents and adults exhibited suboptimal adjustment of their learning rate to environmental volatility. In contrast to the learning rate, it was instead participants' stochasticity (i.e., decision variability) that better resembled the adjustment to volatility made by the optimal RL agent. Although heightened stochasticity in the volatile environment led participants to more often trial different responses that facilitated discovery of changes to the environment, we also found that anxiety impaired this adaptive ability. The finding of heightened stochasticity in volatile environments contradicts expectations that the learning rate is responsible for successful adaptation and motivates future work on the deleterious role that anxiety plays when adolescents manage periods of transition.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven J Granger, Elizabeth A Olson, Sylvie J Weinstein, Isabelle R Vratimos, Brian Lynch, Boyu Ren, Isabelle M Rosso
{"title":"Aberrant neural event segmentation during a continuous social narrative in trauma-exposed older adolescents and young adults.","authors":"Steven J Granger, Elizabeth A Olson, Sylvie J Weinstein, Isabelle R Vratimos, Brian Lynch, Boyu Ren, Isabelle M Rosso","doi":"10.3758/s13415-024-01252-2","DOIUrl":"https://doi.org/10.3758/s13415-024-01252-2","url":null,"abstract":"<p><p>Post-traumatic stress and major depressive disorders are associated with \"overgeneral\" autobiographical memory, or impaired recall of specific life events. Interpersonal trauma exposure, a risk factor for both conditions, may influence how symptomatic trauma-exposed (TE) individuals segment everyday events. The ability to parse experience into units (event segmentation) supports memory. Neural state transitions occur within a cortical hierarchy and play a key role in event segmentation, with regions like the occipital cortex, angular gyrus, and striatum involved in parsing event structure. We examined whether interpersonal trauma exposure was associated with alterations in the cortical hierarchy and striatal activity at neural state transitions in symptomatic TE versus healthy control (HC) individuals. Fifty older adolescents and young adults (29 TE, 21 HC) viewed the film \"Partly Cloudy\" during functional magnetic resonance imaging. A greedy-state boundary search algorithm assessed the optimal number of events, quality, and segmentation agreement of neural state transitions in the occipital cortex and angular gyrus. Striatal (nucleus accumbens, caudate, and putamen) activity was assessed at occipital and angular gyrus-evoked state transitions. Compared to HCs, TE participants displayed less occipital and greater angular gyrus-evoked optimal number of neural state transitions. TE participants also displayed lower quality of neural state segmentation solutions in occipital and angular cortices compared to HCs. Additionally, TE participants had less putamen activity at angular gyrus-evoked state transitions than HCs. This investigation provides neurobiological insights into aberrant event segmentation in symptomatic TE individuals, shedding light on mechanisms influencing overgeneral memory in trauma-related disorders.</p>","PeriodicalId":50672,"journal":{"name":"Cognitive Affective & Behavioral Neuroscience","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}