Colombia Medica最新文献

{"title":"Cerebelitis criptococócica en paciente VIH negativo","authors":"Fabricio Andres Lasso, T. Bastidas, J. A. García, Bairon Díaz Idrobo","doi":"10.25100/CM.V48I2.2289","DOIUrl":"https://doi.org/10.25100/CM.V48I2.2289","url":null,"abstract":"Abstract Introduction: Cryptococcosis is an opportunistic fungal infection whose etiology is Cryptococcus neofromans / C. gattii, complex which affects immunocompromised patients mainly. Meningeal infection is one of the most common presentations, but cerebellar affection is rare. Case Description: Male patient with 65 old years, from an area of subtropical climate with chronic exposure to poultry, without pathological antecedents, who presented clinical picture consistent with headache, fever, seizures and altered mental status. Clinical findings and diagnostic methods: Initially without menigeal signs or intracranial hypertension and normal neurological examination. Later, the patient developed ataxia, dysdiadochokinesia and limb loss. By lumbar punction and image of nuclear magnetic resonance (NMR) cerebellitis cryptococcal was diagnosticated. Treatment: Antifungal therapy with amphotericin B and fluconazole was performed, however the patient died. Clinical Relevance: The cryptococcosis has different presentations, it´s a disease whose incidence has been increasing since the advent of the HIV / AIDS pandemy, however the commitment of the encephalic parenchyma and in particular the cerebellum is considered rare. In this way we are facing the first case of cryptococcal cerebellitis in our midst.","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"65 1","pages":"94-97"},"PeriodicalIF":1.1,"publicationDate":"2017-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82363492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carta al editor sobre artículo titulado\" Afro-Colombian ethnicity, a paradoxical protective factor against dengue\"","authors":"A. Rengifo, María Alexandra Durán, Yamileth Ortíz, J. Rodríguez, M. L. Ospina","doi":"10.25100/CM.V48I2.2935","DOIUrl":"https://doi.org/10.25100/CM.V48I2.2935","url":null,"abstract":"","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"62 1","pages":"98-99"},"PeriodicalIF":1.1,"publicationDate":"2017-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79873513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Es Colombia un país violento","authors":"Andrés Fandiño-Losada, R. Guerrero","doi":"10.25100/CM.V48I1.2979","DOIUrl":"https://doi.org/10.25100/CM.V48I1.2979","url":null,"abstract":"","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"49 1","pages":"9-11"},"PeriodicalIF":1.1,"publicationDate":"2017-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85075781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoreporte de la calidad de vida en niños y adolescentes colombianos: Estudio FUPRECOL","authors":"Darío Fernando Gaitán-López, Jorge Enrique Correa-Bautista, S. Vinaccia, R. Ramírez-Vélez","doi":"10.25100/CM.V48I1.2071","DOIUrl":"https://doi.org/10.25100/CM.V48I1.2071","url":null,"abstract":"\"Describir por autorreporte la calidad de vida relacionada con la salud (CVRS) en una poblacion escolar de Bogota, Colombia, pertenecientes al estudio FUPRECOL.Metodos: Estudio descriptivo y transversal, en 3,245 ninos y 3,354 adolescentes, entre 9 y 17.9 anos de edad, de 24 instituciones educativas oficiales de Bogota, Colombia. Se aplico de manera automaticaadministrada del instrumento de CVRS infantil EQ-5D-Y proxy, version validada al castellano. Se analizaron los datos por medidas detendencia central y se realizo una comparacion de los observados en Colombia con estudios internacionales.Resultados: De la poblacion probada, el 58,3% (n = 3.848), fueron mujeres En general, se observaron observaciones elevadas en la CVRSen ninos y adolescentes de ambos sexos. Al comparar por genero, las dimensiones del proxy EQ-5D-Y “sentirse triste / preocupado o infeliz ”y“ tener dolor / malestar ”, exposicion la mayor frecuencia de respuesta en el grupo de las mujeres. Al comparar los resultados de este estudio, por grupos de edad, con trabajos internacionales de ninos y adolescentes, se realizan que las puntuaciones del proxy EQ-5D-Y fueron superiores a los reportados en Surafrica, Alemania e Italia.Conclusion:Los ninos acusan menor porcentaje de problemas en todas las dimensiones que los adolescentes. Las dimensiones relativasa \"\"dolor / malestar\"\" y \"\"sentirse triste / preocupado o infeliz\"\", fueron en las que se indican mas problemas. Se presentan valores de la CVRSsegun edad y sexo que pueden ser usados ??en la evaluacion de la salud percibida en el ambito escolar en Bogota, Colombia.Articulo originalAutoinforme de la calidad de vida relacionada con la salud en ninos y adolescentes de Bogota, Colombia. El estudio FUPRECOLAutor de la calidad de vida en ninos y adolescentes colombianos: Estudio FUPRECOLDario Fernando Gaitan-Lopez1Jorge Enrique Correa-Bautista1Stefano Vinaccia2Robinson Ramirez-Velez11Centro de Estudios en Medicion de la Actividad Fisica (CEMA), Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogota DC, Colombia. 2Universidad del Sinu, Facultad de Ciencias de la Salud. Programa de Psicologia. Monteria, Colombia.Gaitan-LopezDF, Correa-Bautista JE, Vinaccia E, Ramirez-Velez R. Autoinforme de calidad de vida relacionada con la salud en ninos y adolescentes de Bogota, Colombia. los Estudio FUPRECOL. Colomb Med (Cali). 2017; 48 (1): 12-8.© 2017 Universidad del Valle. Este es un articulo de acceso abierto distribuido bajo los terminos de la licencia de atribucion Creative Commons, que permite el uso sin restricciones,distribucion y reproduccion en cualquier medio, siempre que se acredite el autor original y la fuente.Colombia Medicacolombiamedica.univalle.edu.co\"","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"2 1","pages":"12-18"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86995322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Edición de genes para el tratamiento del cáncer de pulmón (CRISPR-Cas9).","authors":"A. Castillo","doi":"10.25100/CM.V47I4.2856","DOIUrl":"https://doi.org/10.25100/CM.V47I4.2856","url":null,"abstract":"In 2015, the journal Science chose CRISPR-Cas9 technology as the most important technological advance of science in the last years1. This magazine announced the beginning of a new era of biotechnology in which it would be possible to edit, correct and modify the genetic information of any cell in a feasible, fast and cheap way; and most importantly, with high precision. Its implementation in research laboratories in basic and applied sciences could help to develop therapeutic strategies for the health area with the main objective of healing diseases with a known genetic origin, and that until now have been impossible to cure.","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"54 1","pages":"178-180"},"PeriodicalIF":1.1,"publicationDate":"2016-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75276173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polimorfismos en el gen lipoproteína lipasa como marcadores genéticos para enfermedad cerebrovascular en la población colombiana: estudio de casos y controles","authors":"Leydi Carolina Velásquez Pereira, Clara Inés Vargas Castellanos, F. A. S. Sieger","doi":"10.25100/CM.V47I4.1683","DOIUrl":"https://doi.org/10.25100/CM.V47I4.1683","url":null,"abstract":"Objective:To analyze if there is an association between the presence of polymorphisms in the LPL gene (rs320, rs285 and rs328) with development of acute ischemic stroke in Colombian population.Methods:In a case control design, 133 acute ischemic stroke patients (clinical diagnosis and x-ray CT) and 269 subjects without stroke as controls were studied. PCR -RFLP technique was used to detect rs320, rs285 and rs328 polymorphisms in the LPL gene.Results:In the present research was not found any association between any of the LPL gene polymorphism and acute ischemic stroke in the population studied; the allele and genotypic frequencies of the studied polymorphisms were similar in cases and controls and followed the Hardy-Weinberg equilibrium. The study was approved by the IRB and each subject signed the informed consent.Conclusion:LPL gene polymorphisms are not genetic markers for the development of stroke in the Colombian sample used.","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"16 1","pages":"189-195"},"PeriodicalIF":1.1,"publicationDate":"2016-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74665872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin D (25(OH)D) in patients with chronic kidney disease stages 2-5.","authors":"César Augusto Restrepo Valencia, José Vicente Aguirre Arango","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To establish the impact the chronic kidney disease stage has in the native vitamin D levels in patients not undergoing dialysis treatment.</p><p><strong>Methods: </strong>A study performed in Manizales, Colombia, a city located 2,200 meters above sea level, without important stational variations. Patients with 18 years of age or more, with chronic kidney disease stages 2 to 5 and not undergoing dialysis treatment were recruited for this study. Demographic and anthropometric variations were evaluated as well as solar exposure, CKD etiology and laboratory variables related to bone and mineral diseases. For each CKD clinical stage, correlations were evaluated for vitamin D levels, laboratory results for bone and mineral diseases, solar exposure and ethnicity.</p><p><strong>Results: </strong>Three hundred thirty-three patients were evaluated with a median age of 71 years, most of them mestizo (71%), 173 were women. The main CKD etiology was hypertensive nephropathy (32.2%). 21.1% of patients had normal vitamin D levels, 70.1% were within insufficient range and 8.8% were in deficit. A negative correlation was found between the levels of vitamin 25 (OH) D and the values for: creatinine, phosphorous, calcium x phosphorous product, PTH, 24 hours urine protein and BMI. A positive relationship was found for calcium and albumin. Positive significant statistical correlation was found for vitamin 25(OH) D levels and solar exposure for stages 3b and 4 of CKD.</p><p><strong>Conclusions: </strong>It is common to find low levels of vitamin 25(OH) D in patients with CKD; these can contribute to the appearance of secondary hyperparathyroidism.</p><p><strong>Objetivo: </strong>Establecer el impacto del estadio clínico en los niveles de vitamina D nativa en pacientes con enfermedad renal crónica (ERC) sin diálisis.</p><p><strong>Métodos: </strong>Estudio realizado en Manizales, Colombia, una ciudad tropical ubicada a 2,200 metros de altura sobre el nivel del mar, sin variaciones estacionales importantes a lo largo del año. Se incluyeron pacientes mayores de 18 años, con enfermedad renal crónica estadio 2 a 5 sin tratamiento dialítico. En ellos se evaluaron variables demográficas, antropométricas, grado de exposición solar, etiología de la enfermedad, y variables de laboratorio relacionadas con desórdenes óseos y minerales. Para cada estadío clínico se evaluó la correlación entre los niveles de vitamina D y los resultados de las pruebas de laboratorio relacionadas con desordenes óseos y minerales, exposición solar y etnia.</p><p><strong>Resultados: </strong>Se evaluaron 331 pacientes, con una edad media de 71 años, la mayoría mestizos (71%), 173 mujeres. La principal etiología de ERC fue nefropatía hipertensiva (33.2%). El 21.1% de los pacientes tenían niveles normales de vitamina D, fueron insuficientes en 70.1% y 8.8% en déficit. Se detectó correlación negativa, entre los niveles de vitamina 25(OH)D y los valores de creatinina, fósforo","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"47 3","pages":"160-166"},"PeriodicalIF":1.1,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091275/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72211759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trauma Registry of the Pan-American Trauma Society: One year of experience in two hospitals in southwest Colombia.","authors":"Carlos A Ordoñez, Mónica Morales, Johanna Carolina Rojas-Mirquez, Francisco Javier Bonilla-Escobar, Marisol Badiel, Fernando Miñán Arana, Adolfo González, Luis Fernando Pino, Amadeus Uribe-Gómez, Mario Alain Herrera, Maria Isabel Gutiérrez-Martínez, Juan Carlos Puyana, Michael Abutanos, Rao R Ivatury","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Trauma information systems are needed to improve decision making and to identify potential areas of intervention.</p><p><strong>Objective: </strong>To describe the first year of experience with a trauma registry in two referral centers in southwest Colombia.</p><p><strong>Methods: </strong>The study was performed in two referral centers in Cali. Patients with traumatic injuries seen between January 1 and December 31, 2012, were included. The collected information included demographics, mechanism of trauma, injury severity score (ISS), and mortality. A descriptive analysis was carried out.</p><p><strong>Results: </strong>A total of 17,431 patients were registered, of which 67.8% were male with an average age of 30 (±20) years. Workplace injuries were the cause of emergency consultations in 28.2% of cases, and falls were the most common mechanism of trauma (37.3%). Patients with an ISS ≥15 were mostly found in the 18-35-year age range (6.4%). Most patients who suffered a gunshot wound presented an ISS ≥15. A total of 2.5% of all patients died, whereas the mortality rate was 54% among patients with an ISS ≥15 and a gunshot wound.</p><p><strong>Conclusion: </strong>Once the trauma registry was successfully implemented in two institutions in Cali, the primary causes of admission were identified as falls and workplace injuries. The most severely compromised patients were in the population range between 18 and 35 years of age. The highest mortality was caused by gunshot wounds.</p><p><strong>Introducción: </strong>Los sistemas de información en trauma son requeridos para mejorar la toma de decisiones e identificar potenciales áreas de intervención.</p><p><strong>Objetivo: </strong>Describir el primer año de experiencia del registro de trauma en dos centros de referencia de trauma del suroccidente Colombiano.</p><p><strong>Métodos: </strong>Estudio realizado en dos centros de referencia de Cali. Se incluyeron pacientes con trauma o lesiones externas entre el 1-Ene y el 31-Dic-2012. Se recolectó información demográfica, relacionada con mecanismos de trauma, severidad (ISS) y mortalidad. Se presenta un análisis descriptivo.</p><p><strong>Resultados: </strong>Se registraron 17,431 pacientes. El 67.8% de los pacientes eran de género masculino con edad promedio de 30 (±20) años. Las lesiones laborales fueron causa de consulta a urgencias en un 28.2%, y las caídas el mecanismo de trauma más frecuente (37.3%). Los pacientes con ISS ≥15 en su mayoría se encontraban en el rango de edad de 18-35 años (6.4%). El 28% de los pacientes que sufrieron lesión por arma de fuego presentaron un ISS ≥15. El 2.5% de los pacientes murieron y aquellos pacientes con ISS ≥15 y lesión por arma de fuego presentaron mortalidad del 54%.</p><p><strong>Conclusión: </strong>una vez se logró implementar el registro de trauma en dos instituciones en Cali, se identificó que la principal causa de ingreso fue secundaria a caídas y las lesiones laborales. Los p","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"47 3","pages":"148-154"},"PeriodicalIF":1.3,"publicationDate":"2016-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5091273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guía de práctica clínica para la prevención, diagnóstico, tratamiento y seguimiento de la diabetes mellitus tipo 2 en la población mayor de 18 años","authors":"P. Aschner, Oscar Mauricio Muñoz, D. Girón, Olga Milena García, D. F. Fernández Ávila, Luz Ángela Casas, Luisa Fernanda Bohorquez, Clara María Arángo T., L. Carvajal, Doris Amanda Ramírez, J. G. Sarmiento, Cristian Alejandro Colón, Nestor Fabián Correa G., Pilar Alarcón R., Alvaro Andrés Bústamante S.","doi":"10.25100/CM.V47I2.2207","DOIUrl":"https://doi.org/10.25100/CM.V47I2.2207","url":null,"abstract":"In Colombia, diabetes mellitus is a public health program for those \u0000responsible for creating and implementing strategies for prevention, \u0000diagnosis, treatment, and follow-up that are applicable at all care \u0000levels, with the objective of establishing early and sustained control \u0000of diabetes. A clinical practice guide has been developed following \u0000the broad outline of the methodological guide from the Ministry \u0000of Health and Social Welfare, with the aim of systematically \u0000gathering scientific evidence and formulating recommendations \u0000using the GRADE (Grading of Recommendations Assessment, \u0000Development and Evaluation) methodology. The current document \u0000presents in summary form the results of this process, including the \u0000recommendations and the considerations taken into account in \u0000formulating them. \u0000In general terms, what is proposed here is a screening process using the \u0000Finnish Diabetes Risk Score questionnaire adapted to the Colombian \u0000population, which enables early diagnosis of the illness, and an \u0000algorithm for determining initial treatment that can be generalized to \u0000most patients with diabetes mellitus type 2 and that is simple to apply \u0000in a primary care context. In addition, several recommendations \u0000have been made to scale up pharmacological treatment in those \u0000patients that do not achieve the objectives or fail to maintain them \u0000during initial treatment. These recommendations also take into \u0000account the evolution of weight and the individualization of glycemic \u0000control goals for special populations. Finally, recommendations have \u0000been made for opportune detection of micro- and macrovascular \u0000complications of diabetes.","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"37 1","pages":"109-130"},"PeriodicalIF":1.1,"publicationDate":"2016-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73671818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación de la diásquisis transcallosa en un modelo murino de isquemia cerebral focal","authors":"C. Arango-Dávila, B. Muñoz, D. M. Castaño, Laura Potes, John Umbarila","doi":"10.25100/CM.V47I2.2146","DOIUrl":"https://doi.org/10.25100/CM.V47I2.2146","url":null,"abstract":"","PeriodicalId":50667,"journal":{"name":"Colombia Medica","volume":"32 1","pages":"87-93"},"PeriodicalIF":1.1,"publicationDate":"2016-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82669901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}