{"title":"Disseminated tinea incognito due to Trichophyton violaceum in a healthy child.","authors":"Xiang-Dong Wang, Ze-Hu Liu","doi":"10.1016/j.ijid.2022.06.018","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.06.018","url":null,"abstract":"","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"368-372"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39992819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giancarlo Ceccarelli, Silvia Angeletti, Serena Vita, Antonio Crialesi, Marco Ciotti, Ornella Spagnolello, Laura Elena Pacifici, Sivia Fabris, Massimo Ciccozzi, Gabriella d'Ettorre
{"title":"Providing a simple and easily accessible diagnostic tool for HIV diagnosis does not always match success in screening campaigns addressed to migrant populations.","authors":"Giancarlo Ceccarelli, Silvia Angeletti, Serena Vita, Antonio Crialesi, Marco Ciotti, Ornella Spagnolello, Laura Elena Pacifici, Sivia Fabris, Massimo Ciccozzi, Gabriella d'Ettorre","doi":"10.1016/j.ijid.2022.06.015","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.06.015","url":null,"abstract":"","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"373-374"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39992820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Niyas Khalid Ottu Para, Sreya Vemuri, Georgey Koshy, Dima Ibrahim, Seema Oomen, Sudhakar V Reddappa, Mohammad Shoaib Nadaf, Raja Muhammad Irfan, Nicholas Wyon, Mohammed Zeki Ahmed, Supriya Sundaram
{"title":"Management of Cepacia syndrome in an immunocompetent non-cystic fibrosis adult patient.","authors":"Niyas Khalid Ottu Para, Sreya Vemuri, Georgey Koshy, Dima Ibrahim, Seema Oomen, Sudhakar V Reddappa, Mohammad Shoaib Nadaf, Raja Muhammad Irfan, Nicholas Wyon, Mohammed Zeki Ahmed, Supriya Sundaram","doi":"10.1016/j.ijid.2022.07.004","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.07.004","url":null,"abstract":"<p><p>Burkholderia cepacia complex (BCC) is nonfermenting, Gram-negative bacteria known to cause high morbidity and mortality. They commonly affect patients with cystic fibrosis (CF) and are often missed in those without, despite being fatal if left untreated. We report a case of cepacia syndrome in a 42-year-old, immunocompetent man without CF who initially presented with sepsis secondary to pneumonia. Multiple isolates from blood, synovial fluid, and wound swabs grew BCC. Treatment options and management strategies remain poorly understood for BCC in general and in cases without CF in specific. We successfully treated the patient using a combination of intravenous and inhalational antibiotics. This case report elaborates on the disease presentation, investigations, and management strategy employed to treat this rare infection.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"550-552"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40488814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Marie Nathan, Kai Ning Chong, Cindy Shuan Ju Teh, Shih Ying Hng, Kah Peng Eg, Jessie Anne de Bruyne, Anis Najwa Muhamad, Quraisiah Adam, Rafdzah Ahmad Zaki, Nuguelis Razali
{"title":"Colonization of the newborn respiratory tract and its association with respiratory morbidity in the first 6 months of life: A prospective cohort study.","authors":"Anna Marie Nathan, Kai Ning Chong, Cindy Shuan Ju Teh, Shih Ying Hng, Kah Peng Eg, Jessie Anne de Bruyne, Anis Najwa Muhamad, Quraisiah Adam, Rafdzah Ahmad Zaki, Nuguelis Razali","doi":"10.1016/j.ijid.2022.06.049","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.06.049","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to determine the association between newborn bacterial colonization and infant respiratory morbidity in the first 6 months of life.</p><p><strong>Methods: </strong>This prospective study included healthy newborn infants. Nasopharyngeal swabs performed within 72 hours of delivery were analyzed using polymerase chain reaction. We assessed cumulative respiratory morbidity of infants at 6 months.</p><p><strong>Results: </strong>A total of 426 mother-infant pairs were recruited. In 53.3% (n = 225) of newborns, Streptococcus pneumoniae (46%) and Staphylococcus aureus (7.3%) were isolated. None had Haemophilus influenzae nor Moraxella catarrhalis. At the age of 6 months, 50.7% of infants had experienced respiratory symptoms, 25% had unscheduled doctor visits, and 10% were treated with nebulizers. Colonization with S. pneumoniae was associated with reduced risk of any respiratory symptom (adjusted odds ratio [aOR] 0.39, 95% confidence interval [CI] 0.16, 0.50), unscheduled doctor visits (aOR 0.35; 95% CI 0.18, 0.67), and nebulizer treatment (aOR 0.23, 95% CI 0.07, 0.72) at 6 months. Pregnancy-induced hypertension was also associated with increased need for nebulizer treatment (aOR 9.11, 95% CI 1.43, 58.1).</p><p><strong>Conclusion: </strong>Colonization of the newborn respiratory tract occurred in 53% of infants. S. pneumoniae was the most common organism, and this was associated with a reduced risk for respiratory morbidity at 6 months of life.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"712-720"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40511121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeong Rae Yoo, Keun Hwa Lee, Misun Kim, Hyun Joo Oh, Sang Taek Heo
{"title":"Tocilizumab therapy for IL-6 increment in a patient with non-fatal severe fever with thrombocytopenia syndrome.","authors":"Jeong Rae Yoo, Keun Hwa Lee, Misun Kim, Hyun Joo Oh, Sang Taek Heo","doi":"10.1016/j.ijid.2022.06.058","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.06.058","url":null,"abstract":"<p><p>We report the administration of an anti-interleukin (IL)-6 antibody in a case of severe fever with thrombocytopenia syndrome (SFTS) with an increase in IL-6. On the day of admission, SFTS viral load and IL-6 concentration were 93 831 copies/ml and 5.4 pg/ml, respectively, and tocilizumab was administered. SFTS viral load decreased to 17 821.1 copies/ml on the 3<sup>rd</sup> day of admission, while IL-6 levels increased to 104.9 pg/ml; SFTS viral load and IL-6 levels had decreased to 2876.4 copies/ml and 48.2 pg/ml on 7<sup>th</sup> day of admission, respectively. The patient fully recovered no tocilizumab adverse events.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"656-658"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40571635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical features and prognostic predictors in patients with rheumatic diseases complicated by Pneumocystis pneumonia.","authors":"Yi-Min Huang, Cheng-Hsun Lu, Chiao-Feng Cheng, Chieh-Yu Shen, Song-Chou Hsieh, Ko-Jen Li, Jung-Yien Chien, Po-Ren Hsueh","doi":"10.1016/j.ijid.2022.07.070","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.07.070","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the clinical outcomes and risk factors of mortality in patients with rheumatic diseases complicated by Pneumocystis pneumonia (PCP).</p><p><strong>Methods: </strong>Between November 2015 and April 2021, patients with rheumatic diseases with PCP in a tertiary referral hospital were retrospectively enrolled. The diagnosis of PCP requires the fulfillment of clinical, radiographic, and microbiological criteria. Factors associated with in-hospital, 30-day, and 90-day mortality were evaluated.</p><p><strong>Results: </strong>A total of 128 patients with rheumatic diseases who had a positive quantitative polymerase chain reaction assay for Pneumocystis jirovecii were screened, and 72 patients were included in the final analysis. The median (interquartile range [IQR]) pneumonia severity index (PSI) was 101.5 (77.0-132.0). The median (IQR) adjunctive corticosteroid dosage was 0.6 (0.4-0.9) mg/kg/day prednisolone equivalent. The receiver operating characteristic curve analysis showed that the optimal cutoff point of median adjunctive corticosteroid dosage was 0.6 mg/kg/day to predict in-hospital, 30-day, and 90-day mortality. In the multivariable logistic regression analysis, median adjunctive corticosteroid dosage ≥0.6 mg/kg/day and PSI >90 were independent factors of in-hospital, 30-day, and 90-day mortality.</p><p><strong>Conclusion: </strong>A median adjunctive corticosteroid dosage of ≥0.6 mg/kg/day might be associated with mortality in patients with rheumatic diseases complicated by PCP.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"1018-1025"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40676206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tingting Yue, Quanquan Zhang, Ting Cai, Ming Xu, Haizhen Zhu, Mahmoud Reza Pourkarim, Erik De Clercq, Guangdi Li
{"title":"Trends in the disease burden of HBV and HCV infection in China from 1990-2019.","authors":"Tingting Yue, Quanquan Zhang, Ting Cai, Ming Xu, Haizhen Zhu, Mahmoud Reza Pourkarim, Erik De Clercq, Guangdi Li","doi":"10.1016/j.ijid.2022.06.017","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.06.017","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to reveal the 30-year dynamics of hepatitis B virus (HBV) and hepatitis C virus (HCV) disease burden in China from 1990-2019.</p><p><strong>Methods: </strong>HBV/HCV data were retrieved from the Global Burden of Disease database. Joinpoint regression was used to examine temporal trends. Age-period-cohort models were applied to evaluate effects of patient age, period, and cohort on HBV/HCV-associated mortality and incidences.</p><p><strong>Results: </strong>A dramatic decrease in the disease burden of HBV was found from 1990-2019, but the disease burden of HCV has remained stable since 2000. Patient age, period, and cohort exerted a significant effect on the diseases burden of HBV and HCV infection. Compared with women, men had a higher risk of HBV/HCV infections as well as HBV/HCV-associated mortality and liver cancer. Overweight, alcohol, tobacco, and drug use were important risk factors associated with HBV/HCV-associated liver cancer. The incidences of HBV- and HCV-associated liver cancer from 2019-2044 are expected to decrease by 39.4% and 33.3%, respectively.</p><p><strong>Conclusion: </strong>The disease burden of HBV/HCV infection has decreased in China over the past 30 years, but HBV incidences remain high, especially in men. Effective management of HBV and HCV infections is still needed for high-risk populations.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"476-485"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40086928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Omadacycline in first-line combination therapy for pulmonary Mycobacterium abscessus infection: a case series.","authors":"Marylene Duah, Melissa Beshay","doi":"10.1016/j.ijid.2022.06.061","DOIUrl":"https://doi.org/10.1016/j.ijid.2022.06.061","url":null,"abstract":"<p><p>Mycobacterium abscessus complex (MABSC) represents the second most common cause of nontuberculous mycobacterial pulmonary disease, associated with up to 17% of cases. Treatment of MABSC disease is complex, lengthy, and involves multidrug regimens due to high rates of intrinsic antimicrobial resistance; cure rates remain poor. There are currently no approved treatments for MABSC, and only limited data are available to guide treatment decisions for individual patients. Omadacycline, a tetracycline class-derived aminomethylcycline that is not approved for treatment of nontuberculous mycobacterial pulmonary infections, has been granted orphan drug designation by the US Food and Drug Administration. Here, we describe three cases using omadacycline as part of a first-line treatment regimen for patients with MABSC pulmonary infections, based on multiple factors, including resistance profile, toxicity, minimizing use of intravenous therapy, and expert recommendation. The clinical improvements of these patients, together with promising in vitro and early clinical development data, indicate that omadacycline warrants further investigation as a potential first-line option for incorporating into MABSC pulmonary disease treatment regimens.</p>","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"953-956"},"PeriodicalIF":8.4,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40578819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Lucero, A J Lagomarcino, J P Torres, P Roessler, N Mamani, S George, N Huerta, M Gonzalez, M O'Ryan
{"title":"Corrigendum to \"Helicobacter pylori, clinical, laboratory, and noninvasive biomarkers suggestive of gastric damage in healthy school-aged children: A case-control study\" [Int. J. Infect. Dis. 103 (2021) 423-430].","authors":"Y Lucero, A J Lagomarcino, J P Torres, P Roessler, N Mamani, S George, N Huerta, M Gonzalez, M O'Ryan","doi":"10.1016/j.ijid.2021.05.046","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.05.046","url":null,"abstract":"","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"125"},"PeriodicalIF":8.4,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.05.046","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38984859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rhino-orbital Entomophthoromycosis.","authors":"Yanling Liu, Ying Zhang, Jing Ye, Danqing Yan","doi":"10.1016/j.ijid.2021.05.081","DOIUrl":"https://doi.org/10.1016/j.ijid.2021.05.081","url":null,"abstract":"","PeriodicalId":505767,"journal":{"name":"International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases","volume":" ","pages":"522-523"},"PeriodicalIF":8.4,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.ijid.2021.05.081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39080771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}