Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

{"title":"Echocardiographic Nomogram Model: A Tool for Assessing Cardiac Involvement in Patients With Systemic Amyloidosis.","authors":"Qiongwen Lin, Xiaoshan Li, Zekun Tan, Ruixue Xu, Hongwen Fei, Oudi Chen","doi":"10.1111/echo.70252","DOIUrl":"https://doi.org/10.1111/echo.70252","url":null,"abstract":"<p><strong>Objectives: </strong>Cardiac involvement is significantly relevant to a poor prognosis in patients with systemic amyloidosis, often leading to adverse outcomes. The objective of this study was to develop a diagnostic model for cardiac amyloidosis (CA) in primary light chain amyloidosis (pAL) to facilitate early detection and improve prognostic evaluation.</p><p><strong>Methods: </strong>In this retrospective study involving 72 patients with primary pAL amyloidosis (51 with cardiac involvement), we systematically employed cardiac magnetic resonance imaging (CMR) for cardiac assessment. CA diagnosis was confirmed histologically via noncardiac tissue biopsy, positive for light chain systemic amyloidosis. To dissect the risk factors for cardiac involvement, we applied both univariate logistic regression and a random forest algorithm. Subsequently, the findings from these analyses informed the construction of a predictive nomogram. We rigorously evaluated the nomogram's performance using receiver operating characteristic curve analysis, calibration curve assessment, and decision curve analysis.</p><p><strong>Results: </strong>The nomogram model included relative wall thickness (RWT), the ratio of mitral peak flow velocity in early diastolic (E wave) to the pulsed tissue Doppler imaging-derived early diastolic peak velocity (e' wave) at the interventricular septal mitral annulus (E/e' sep), ejection fraction to peak systolic global longitudinal strain ratio (EFSR) and right ventricular fractional area change (RV FAC). The model exhibited good diagnostic performance, with an area under the ROC curve of 0.85 (95% CI, 0.75-0.92), a sensitivity of 80.4% (95% CI, 66.9%-90.2%), and a specificity of 85.7% (95% CI, 63.7%-97.0%).</p><p><strong>Conclusions: </strong>The nomogram provided a noninvasive and effective means of assessing cardiac involvement in systemic amyloidosis, offering a valuable aid for clinical decision-making and patient management.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":"e70252"},"PeriodicalIF":1.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silent Invader: A Rare Right Ventricular Lipoma Resolved With Multimodal Imaging","authors":"Jie Wang,&nbsp;Ping Hu,&nbsp;Huan Yuan,&nbsp;Hong Yan,&nbsp;Xiao-Jing Ma","doi":"10.1111/echo.70230","DOIUrl":"https://doi.org/10.1111/echo.70230","url":null,"abstract":"<div>\u0000 \u0000 <p>A 36-year-old female with bilateral thyroid cancer was incidentally found to have a 5.6×4.3 cm right ventricular (RV) mass, confirmed by TTE and cardiac CT as a fat-density lesion. Multimodal imaging, including Myocardial contrast echocardiography (MCE), CT, and CMR, helped diagnose the mass as a cardiac lipoma and guided surgical planning, which successfully removed the tumor and restored RV dimensions. This case highlights the critical role of multimodal imaging in diagnosing and managing rare cardiac tumors.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144716841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sound Waves Versus Pressure Waves: The Increasing Role of Echocardiography and Noninvasive Vasoreactivity Testing in Pediatric Pulmonary Hypertension Management","authors":"John T. Wren Jr.,&nbsp;Kamel Shibbani","doi":"10.1111/echo.70254","DOIUrl":"https://doi.org/10.1111/echo.70254","url":null,"abstract":"&lt;p&gt;Pediatric pulmonary hypertension (PH) is a complex disease with significant morbidity and mortality and affects patients from infancy to adolescence. Although defined simply as an elevation in pulmonary artery pressure (PAP) [&lt;span&gt;1&lt;/span&gt;], an understanding of the precise etiology is needed to target appropriate management strategies. This understanding can be derived from Ohm's law, which states that the voltage across two points is a function of flow of electric charge multiplied by resistance (&lt;i&gt;V&lt;/i&gt; = &lt;i&gt;I&lt;/i&gt; x &lt;i&gt;R&lt;/i&gt;). When modified for physiology, this posits that the pressure difference across an organ is a function of the flow of blood into that organ multiplied by resistance (Δ&lt;i&gt;P&lt;/i&gt; = &lt;i&gt;Q&lt;/i&gt; x &lt;i&gt;R&lt;/i&gt;). If the organ of interest is the lung, the formula then becomes PAP - pulmonary capillary wedge pressure (PCWP) = pulmonary vascular resistance (PVR) x pulmonary blood flow (PBF), or when rearranged PAP = (PVR x PBF) + PCWP. Elevated PVR, increased PBF, or increased PCWP can all independently lead to PH. The preponderance of pediatric PH is due to elevated PVR and is also known as precapillary hypertension or pulmonary arterial hypertension (PAH) [&lt;span&gt;2&lt;/span&gt;]. However, left to right shunts driving excess PBF or diastolic dysfunction causing elevated PCWP will both raise PAP as well and are frequently encountered in neonates and children [&lt;span&gt;2, 3&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Elucidating these phenotypes and guiding management in pediatric patients requires frequent hemodynamic assessments. The gold standard for this remains right heart catheterization (RHC) and acute vasoreactivity testing (AVT) [&lt;span&gt;2, 4&lt;/span&gt;]. However, this procedure is significantly more limited in the pediatric population owing to clinical instability, need for general anesthesia, absence of standardized guidelines, and subspecialty provider availability [&lt;span&gt;5, 6&lt;/span&gt;]. In its place, transthoracic echocardiography (TTE) provides a significantly more accessible and noninvasive modality to assess pulmonary hemodynamics [&lt;span&gt;7&lt;/span&gt;]. There is a paucity of data, however, regarding the key determination of vasoreactivity responsiveness (and its implications for management and prognostication) in pediatric PH via TTE.&lt;/p&gt;&lt;p&gt;In this edition of &lt;i&gt;Echocardiography&lt;/i&gt;, Simpkin et al. [&lt;span&gt;8&lt;/span&gt;] compare simultaneous TTE- and RHC-based measures of hemodynamics under both baseline and maximal vasodilatory conditions (oxygen and inhaled nitric oxide [iNO]). Although important to benchmark noninvasive metrics with a gold standard, the true value in this study lies in its identification of three noninvasive TTE markers that can predict invasive AVT responsiveness [&lt;span&gt;8&lt;/span&gt;]. This has implications for both the neonatal and pediatric populations.&lt;/p&gt;&lt;p&gt;Neonatal PH is a particularly complex disease process owing to the confounding effects of prematurity, rapid changes in PVR, and the presence of shunts. Unfortunately, the diagnostic power of RHC and AVT","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70254","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144716842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Athlete's Heart and Left Ventricular Strain: The Answer or a New Question?","authors":"Gonzalo Diaz Babio","doi":"10.1111/echo.70250","DOIUrl":"https://doi.org/10.1111/echo.70250","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144688049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Cholesterol Remnants and Cardiac Structure and Function: The Copenhagen City Heart Study","authors":"Emilie S. Galatius,&nbsp;Mats C. Højbjerg Lassen,&nbsp;Kristoffer Grundtvig Skaarup,&nbsp;Niklas Dyrby Johansen,&nbsp;Søren Galatius,&nbsp;Gorm Boje Jensen,&nbsp;Peter Schnohr,&nbsp;Rasmus Møgelvang,&nbsp;Tor Biering-Sørensen","doi":"10.1111/echo.70249","DOIUrl":"https://doi.org/10.1111/echo.70249","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Aims&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;A causal relationship between ischemic heart disease and cholesterol remnants (CR) has been suggested by genetic studies. We studied whether CR are associated with alterations in cardiac structure and function, as evaluated by sensitive echocardiographic measures in individuals without known heart disease.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;All participants from the 5th Copenhagen City Heart Study without known heart disease underwent a comprehensive echocardiography including two-dimensional speckle tracking analysis. CR levels were calculated from lipid analyses in non-fasting venous blood samples.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The study included 3792 participants. Mean age was 55 years and 42% were male. In multivariable analyses adjusted for age, sex, body mass index, hypertension, diabetes and smoking status, increasing levels of CR were significantly associated with alterations in cardiac function, demonstrated as decreasing left ventricular ejection fraction (stand. &lt;i&gt;β&lt;/i&gt;-coef. = −0.060, &lt;i&gt;p&lt;/i&gt; = 0.001), a decreasing global longitudinal strain (stand. &lt;i&gt;β&lt;/i&gt;-coef. = −0.045, &lt;i&gt;p&lt;/i&gt; = 0.014), and a decreasing E/A ratio (stand. &lt;i&gt;β&lt;/i&gt;-coef. = −0.110, &lt;i&gt;p&lt;/i&gt; &lt; 0.001). This association was significantly stronger than the association with cardiac alterations and LDL levels. Additionally, increasing levels of CR were associated with alterations in cardiac structure in the univariable analysis, but these associations were attenuated after multivariable adjustment.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;In a general population sample without known heart disease both impaired systolic and diastolic function were present with increasing levels of CR. This association was stronger than the association between cardiac alterations and LDL-cholesterol levels. The findings support the need for additional research in the potential effect of CR on cardiac health.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Summary&lt;/h3&gt;\u0000 \u0000 &lt;div&gt;\u0000 &lt;ul&gt;\u0000 \u0000 &lt;li&gt;This study investigates the association between cholesterol remnants and cardiac structure and function in 3792 individuals without known heart disease.&lt;/li&gt;\u0000 \u0000 &lt;li&gt;Utilizing sensitive echocardiographic measures, we observed a significant association between increasing cholesterol remnant levels and compromised cardiac function, including reduced left ventricular ejection fraction, global longitudinal strain, and E/A ratio.&lt;/li&gt;\u0000 \u0000 &lt;li&gt;This as","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apical Hypertrophic Cardiomyopathy: A Clinical & Multimodality Imaging Assessment","authors":"Izhan Hamza,&nbsp;Esosa Odigie-Okon,&nbsp;Tianrong Xie,&nbsp;Masood Ahmad","doi":"10.1111/echo.70235","DOIUrl":"https://doi.org/10.1111/echo.70235","url":null,"abstract":"<div>\u0000 \u0000 <p>Apical Hypertrophic Cardiomyopathy (ApHCM) is a distinct phenotypic variant of hypertrophic cardiomyopathy, defined by localized thickening of the left ventricular (LV) apex ≥15 mm in end-diastole. It presents unique diagnostic and management challenges, with clinical presentations ranging from asymptomatic individuals to those experiencing angina, dyspnea, or arrhythmias. Transthoracic echocardiography remains the first-line imaging modality but is often limited by suboptimal apical visualization. Contrast-enhanced echocardiography is recommended to improve diagnostic accuracy, particularly for identifying apical hypertrophy, apical aneurysms, and thrombi. Echocardiography also plays a key role in assessing left ventricular outflow tract obstruction, detecting concomitant mitral valve abnormalities, and guiding periprocedural planning. Cardiac magnetic resonance imaging (CMR) provides superior spatial resolution and tissue characterization. It is the gold standard for evaluating apical wall thickness, detecting apical aneurysms, and quantifying myocardial fibrosis through late gadolinium enhancement. CMR-based markers such as LGE burden and aneurysm size are valuable for sudden cardiac death risk stratification. Additional imaging modalities, including cardiac computed tomography and nuclear perfusion imaging, are important adjuncts when CMR is contraindicated or when evaluation for coronary artery disease is necessary. This review underscores the central role of multimodality imaging in the diagnosis, risk assessment, and management of ApHCM. Future research should focus on refining risk prediction tools to improve individualized care and clinical outcomes in this unique cardiomyopathy subtype.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144647604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent Systemic Embolization in a Patient With Aortic Valve Amyloidosis","authors":"Annalisa Caputo,&nbsp;Amedeo Pergolini,&nbsp;Luigi Monticelli,&nbsp;Enrico Natale,&nbsp;Antonio Lio,&nbsp;Maria Cristina Macciomei,&nbsp;Giulia D'Amati,&nbsp;Martina Leopizzi,&nbsp;Carla Manzara","doi":"10.1111/echo.70241","DOIUrl":"https://doi.org/10.1111/echo.70241","url":null,"abstract":"<p>A rare case of a 47-year-old woman with recurrent thromboembolic events, including STEMI and lower limb ischemia, diagnosed with aortic valve thrombosis caused by isolated aortic valve amyloidosis in the setting of overlapping antiphospholipid syndrome.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144624735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninvasive Left Ventricular Pressure-Strain Loop for Assessment of Myocardial Work in Hemodialysis in Patients With Chronic Kidney Disease","authors":"Yunxiang Miao,&nbsp;Lin Fan,&nbsp;Bingyuan Zhou,&nbsp;Yuping Liao,&nbsp;Ying Yin","doi":"10.1111/echo.70243","DOIUrl":"https://doi.org/10.1111/echo.70243","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To explore the value of a novel echocardiographic measure—left ventricular pressure-strain loop (LV-PSL) for assessment of patients with chronic kidney disease by comparing the changes before and after hemodialysis (HD).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 117 patients undergoing regular hemodialysis were recruited. Global longitudinal strain (GLS) combined with cuff blood pressure measurement is used to calculate the global work index (GWI), global constructive work (GCW), global wasted work (GWW), and global work efficiency (GWE). The differences in echocardiographic parameters before and after hemodialysis on the same day were compared. Additionally, 50 healthy individuals were included as the control group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared with the control group, both the pre-HD and post-HD groups exhibited significantly lower GLS and GWE (pre-HD: <i>p</i> = 0.006 and <i>p</i> = 0.000, respectively; post-HD: <i>p</i> = 0.000 and <i>p</i> = 0.000, respectively). In contrast, the pre-HD group had significantly higher values in PSD, GWI, GCW, and GWW (<i>p</i> = 0.000 for PSD and GWW; <i>p</i> = 0.001 for GWI and GCW). Notably, the post-HD group also had higher values in PSD and GWW compared to the control group (<i>p</i> = 0.000 for both), while no significant differences were observed in GWI and GCW between the post-HD and control groups (<i>p</i> = 0.247 and <i>p</i> = 0.134, respectively).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The LV-PSL parameters are capable of effectively assessing myocardial work in HD patients. Moreover, these parameters offer novel reference indicators for evaluating volume load and left ventricular myocardial function in HD patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70243","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144606454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Global Post-Systolic Contraction During 1st Interstage Predicts Medium-Term Death or Transplantation in Children With Hypoplastic Left Heart Syndrome","authors":"Danielle Harake,&nbsp;Eva Kapravelou,&nbsp;Luke Eckersley,&nbsp;Edythe Tham,&nbsp;Timothy Colen,&nbsp;Lily Lin,&nbsp;Sachie Shigemitsu,&nbsp;Mirza Beigh,&nbsp;Amol Moray,&nbsp;Nee Scze Khoo","doi":"10.1111/echo.70244","DOIUrl":"https://doi.org/10.1111/echo.70244","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Echocardiography parameters of right ventricular (RV) dysfunction, fractional area change (RVFAC), and global longitudinal strain during the first interstage have been shown to be associated with death or transplantation in patients with HLHS. However, both parameters lack adequate discriminatory characteristics. This study sought to examine global post-systolic contraction (PSC), a marker of myocardial inefficiency, as a predictor of death or transplantation (Tx) in patients with classic hypoplastic left heart syndrome (HLHS).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We performed a post-hoc analysis of 62 prospectively recruited patients with HLHS prior to the bidirectional cavopulmonary anastomosis (BCPA) surgery. We measured RV function parameters: RVFAC, global longitudinal strain, strain rate, mechanical dispersion index (MDI), and PSC. For each parameter, the receiver operating characteristic analysis determined the optimal cut-offs for the primary endpoint of death/Tx, followed by a Kaplan-Meier analysis. Parameters interobserver variability testing was performed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Median follow-up from pre-BCPA echocardiogram was 7.4 years. HLHS with outcome of death/Tx (<i>n</i> = 14) had lower RVFAC, longitudinal strain and strain rate, and increased PSC when compared with survivors. PSC of &gt;5% performed the best, with the greatest area under the curve 0.75, sensitivity 64% and specificity 83%, hazard ratio 5.54 (95% CI 1.63–18.66), for the primary endpoint of death/Tx. PSC and strain parameters had excellent reproducibility.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Increased global post-systolic contraction during the first interstage is associated with an outcome of death or transplantation in the medium term follow up of patients with HLHS. PSC has a greater specificity and reproducibility than global longitudinal strain and RV FAC. Investigation into its use in clinical practice as a predictor of outcome is warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70244","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144606610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing Echocardiographic Assessment of Right Ventricular Function in Inferior STEMI","authors":"Bülent Özlek,&nbsp;Veysel Ozan Tanık,&nbsp;Süleyman Barutçu","doi":"10.1111/echo.70246","DOIUrl":"https://doi.org/10.1111/echo.70246","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 7","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}