Electromagnetic Biology and Medicine最新文献

{"title":"Impact of expectancy on fatigue by exposure to the fifth generation of mobile communication signals.","authors":"Lei Yang, Xiaotong Ding, Shun Zhang, Tongning Wu","doi":"10.1080/15368378.2025.2496151","DOIUrl":"10.1080/15368378.2025.2496151","url":null,"abstract":"<p><p>There is a long-standing debate about the relationship between Radio Frequency Electromagnetic Field (RF-EMF) exposure and fatigue. Past studies primarily rely on self-report scales to assess fatigue, but these methods are often susceptible to personal biases. Notably, the role of psychological factors in the fatigue response induce by RF-EMF exposure remains unclear. Therefore, our study focuses on exploring the impact of 5 G signal exposure on human fatigue, particularly considering the influence of expectancy induced by psychological priming on the outcomes. In this study, we recruited 21 healthy subjects who were tested in three sessions. Each session included two 30-min exposures to either real or sham 5 G signals, with the order randomized. The experiment was conducted under varying informational conditions: subjects were provided with correct, false, or no information about the order of exposure. Additionally, subjects completed a fatigue scoring questionnaire and underwent Electroencephalogram (EEG) measurements during the experiment. The statistical comparison indicates that 5 G RF-EMF exposure at routine levels does not lead to changes in EEG power. The finding reveals that the report of fatigue can be altered by the conveyed information of being exposed by 5 G signals although there is no real exposure and no detectable electrophysiological indicator. Our findings suggest that it is necessary to prevent psychological priming in any kind or to take its possible consequence into consideration, to reveal this effect of RF-EMF exposure.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"267-278"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An ECG signal processing and cardiac disease prediction approach for IoT-based health monitoring system using optimized epistemic neural network.","authors":"B Sushma, P Chinniah, P S Ramesh, Balasubbareddy Mallala","doi":"10.1080/15368378.2025.2503334","DOIUrl":"10.1080/15368378.2025.2503334","url":null,"abstract":"<p><p>The rising prevalence of cardiac diseases necessitates advanced IoT-driven health monitoring systems for early detection and diagnosis. This study presents an efficient ECG-based cardiac disease prediction framework leveraging a multi-phase approach to enhance computational efficiency and classification accuracy. The Convolutional Lightweight Deep Auto-encoder Wiener Filter (CLDAWF) is employed for signal preprocessing, while the Quantized Discrete Haar Wavelet Transform (QD-HWT) extracts critical cardiac features, including P-wave fluctuations, QRS complex, and T-wave intervals. These refined features are classified using an optimized Epistemic Neural Network (ENN), whose parameters are fine-tuned via the Boosted Sooty Tern Optimization algorithm, improving accuracy and reducing system loss. The proposed model achieves 99.65% accuracy, demonstrating its effectiveness in real-time cardiac disease monitoring and offering a scalable, high-performance solution for IoT-based healthcare systems.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"325-347"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the influence of Schumann resonance and electromagnetic fields on bioelectricity and human health.","authors":"Igor Nelson","doi":"10.1080/15368378.2025.2508466","DOIUrl":"10.1080/15368378.2025.2508466","url":null,"abstract":"<p><p>This article explores the relationship between electromagnetic fields (EMF) and biological systems, focusing on the influence of extremely low-frequency electromagnetic frequencies (ELF), particularly Schumann's resonance (SR) at 7.83 hz. Cells and proteins may have evolved to take advantage of frequencies naturally present in the Earth's EMF, potentially enhancing cellular energy levels and affecting resting membrane potential (RMP). Thus, changes in or absence of SR may have adverse effects on the functioning of the whole organism. Bioelectricity, independent of genes, has been shown to modulate health, suggesting the potential for using controlled application of EMF frequencies in treating certain types of cancer or conditions affecting the RMP. Research indicates that human brainwave activity is highly dependent on the SR, implying a correlation between atmospheric electromagnetic frequencies and brain activity. ELF, including SR, appears to modulate cellular calcium influx/efflux, likely via indirect mechanisms involving field-sensitive molecules or radical pairs that affect ion channel behavior which plays a critical role in cell signaling and regulation of various processes. It can also trigger a cascade of molecular events that ultimately lead to the generation of action potentials, affecting consciousness and behavior. The influence of atmospheric electromagnetic frequencies on human brainwave activity, modulation of cellular calcium influx/efflux, and potential effects on cellular energy levels and RMP highlight the significance of ELF in biological systems. However, further research is required to fully understand these mechanisms and their implications for human health and well-being.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"348-358"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuro-computational simulation of blood flow loaded with gold and maghemite nanoparticles inside an electromagnetic microchannel under rapid and unexpected change in pressure gradient.","authors":"Poly Karmakar, Sukanya Das, Sayan Das, Sanatan Das","doi":"10.1080/15368378.2025.2453923","DOIUrl":"10.1080/15368378.2025.2453923","url":null,"abstract":"<p><p>In cardiovascular research, electromagnetic fields generated by Riga plates are utilized to study or manipulate blood flow dynamics, which is particularly crucial in developing treatments for conditions such as arterial plaque deposition and understanding blood behavior under varied flow conditions. This research predicts the flow patterns of blood enhanced with gold and maghemite nanoparticles (gold-maghemite/blood) in an electromagnetic microchannel influenced by Riga plates with a temperature gradient that decays exponentially, under sudden changes in pressure gradient. The flow modeling includes key physical influences like radiation heat emission and Darcy drag forces in porous media, with the flow mathematically represented through unsteady partial differential equations solved using the Laplace transform (LT) method. Results, including shear stress (SS) and rate of heat transfer (RHT), are graphically detailed, demonstrating changes in blood velocity profile with modifications in the Hartmann number and the width of electrodes, and differences in temperature and RHT between hybrid nano-blood (HNB) and nano-blood (NB). The key results indicate an increase in blood velocity distribution with higher modified Hartmann number, and a decrease with wider electrodes. Temperature is elevated in both hybrid nano-blood (HNB) and nano-blood (NB). Notably, HNB with gold and maghemite enhances heat transmission in the flow. Furthermore, an artificial intelligence-driven methodology employing an artificial neural network (ANN) has been incorporated to facilitate rapid and precise evaluations of SS and RHT, demonstrating remarkable predictive accuracy. The proposed algorithm exhibits outstanding accuracy, achieving 99.998% on the testing dataset and 96.843% during cross-validation for predicting SS, and 100% on the testing dataset, and 95.008% during cross-validation for predicting RHT. The implementation of nanotechnology with artificial intelligence promises new tools for doctors and surgeons, potentially transforming patient care in fields such as oncology, cardiology, and radiology. This model also facilitates the generation of precise electromagnetic fields to guide drug-loaded magnetic nanoparticles for applications in targeted drug delivery, hyperthermia treatment, MRI contrast enhancement, blood flow monitoring, cancer treatment, and controlled drug release.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"137-172"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS.","authors":"Long Ma, Shijun Bao, Xiwen Yang, Hanyue Liu, Yanlan Xiao, Xiaoting Lin, Xinyue Cui, Qingwei Zhao, Jia-Feng Wang, Hongli Yan, Zhiyong Liu, Youxiang Guo, Jiaming Guo","doi":"10.1080/15368378.2025.2513901","DOIUrl":"10.1080/15368378.2025.2513901","url":null,"abstract":"<p><p>Nuclear electromagnetic pulse (NEMP) as a public hygiene issue has aroused increasing attention. Recent research has demonstrated that NEMP can disrupt the male reproductive system. Molecular hydrogen, a selective hydroxyl radical scavenger, has been shown to have the protective effects against many diseases closely associated with oxidative damage. We sought to characterize the beneficial effects of molecular hydrogen on the male reproductive cells. GC-1 spermatogonial cells and TM-3 Leydig cells, two well-established male reproductive cell lines, were exposed to NEMP. Finally, we employed transcriptomic sequencing to explore the transcriptional changes in male reproductive cells induced by NEMP exposure. For the intervention, cells were incubated in hydrogen gas (H₂ 75%, O₂ 20%, and CO₂ 5%) for 1 h. NEMP exposure induced damage to both GC-1 and TM-3 cells, resulting in decreased cell viability and increased apoptosis rates. However, intervention with molecular hydrogen significantly mitigated this damage. Specifically, molecular hydrogen reduced the production of ROS and restored mitochondrial function, thereby alleviating oxidative stress and apoptosis. Transcriptomic sequencing analysis showed that NEMP affected the molecular function term antioxidant activity, particularly Gstp2, a gene predicted to be located in the mitochondria to promote glutathione transferase activity. Hence, molecular hydrogen is a promising protective agent against NEMP in the mechanism that other antioxidants cannot be available.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"405-417"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective effects of quercetin against 3.5 GHz RF radiation-induced thyroid dysfunction and oxidative stress in rats.","authors":"Hava Bektas, Burcu Buse Bese Akgun, Serife Cakir, Semih Dogu, Bedia Ahnas","doi":"10.1080/15368378.2025.2528732","DOIUrl":"10.1080/15368378.2025.2528732","url":null,"abstract":"<p><p>The global expansion of 5 G communication networks has heightened concerns about the biological effects of high-frequency radiofrequency (RF) radiation, particularly on endocrine organs such as the thyroid gland. This study investigated the effects of 3.5 GHz RF radiation on thyroid hormone levels and oxidative stress markers in male Wistar rats and assessed the potential protective role of quercetin, a natural antioxidant. Twenty-eight rats were randomly assigned to four groups: Sham, RF, Quercetin, and RF + Quercetin. RF exposure was administered at 3.5 GHz (2 W) for 2 hours/day, 5 days/week, for 30 days. Quercetin (20 mg/kg) was administered intraperitoneally. Serum levels of T3, T4, and TSH, as well as thyroid tissue levels of TAS, TOS, GSH, and MDA, were analyzed using ELISA. RF exposure significantly decreased T3 and T4, increased TSH, elevated MDA and TOS, and reduced TAS and GSH levels. Quercetin treatment showed trends toward reversing some of these effects, although not all changes reached statistical significance. SAR simulations confirmed higher energy absorption in the thyroid region (average SAR: 1.128 W/kg). These findings suggest that 3.5 GHz RF radiation may impair thyroid function and redox homeostasis, and that quercetin may exert limited biochemical protection, though further studies are needed to confirm its efficacy. Further long-term molecular studies are warranted to elucidate the mechanisms involved.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"449-460"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 60 Hz magnetic fields on social feeding behavior of <i>npr-1</i> receptor mutants in <i>Caenorhabditis elegans</i>.","authors":"Makiko Kakikawa, Ami Kenmochi, Sotoshi Yamada","doi":"10.1080/15368378.2025.2523773","DOIUrl":"10.1080/15368378.2025.2523773","url":null,"abstract":"<p><p>Previous studies indicated that magnetic fields (MF) could alter the conformation of membrane proteins such as some drug influx transporters and affect their function. In this study, we focused on two mutants of <i>npr-1</i> receptor gene related to feeding behavior in <i>Caenorhabditis elegans</i> (<i>C. elegans)</i> to investigate the effect of 60 Hz, 50 mT MF on a receptor in neurotransmission. The wild-type laboratory strain Bristol N2 in <i>C. elegans</i> forages solitary on the <i>E. coli</i> lawn, whereas <i>npr-1</i> mutant of N2 aggregate on food and take on social feeding behavior because of its altered function. Under MF exposure, the number of aggregates exhibiting social feeding behavior on two mutants, IM222 and DA609, was decreased by 40% and 25%, respectively. Meanwhile, <i>npr-1</i> is not involved in the behavior to attractant diacetyl in <i>C. elegans</i>, and the moving speed and reach rate to attractant in two mutants was not affected by MF exposure for up to 90 min. The results indicate that MF can affect the altered function of NPR-1 in mutant strains and partially change the feeding behaviour of the <i>npr-1</i> mutants from social to solitary. Furthermore, considering the position of these amino acid substitutions in NPR-1 mutant receptors, the extracellular parts of membrane protein may be more affected by MF than the transmembrane part.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"425-433"},"PeriodicalIF":1.5,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ubiquitous extremely low frequency electromagnetic fields induces anxiety-like behavior: mechanistic perspectives.","authors":"Ehsan Hosseini","doi":"10.1080/15368378.2024.2380305","DOIUrl":"10.1080/15368378.2024.2380305","url":null,"abstract":"<p><p>Anxiety is an adaptive condition characterized by heightened uneasiness, which in the long term can cause complications such as reducing the quality of life and problems related to the mental and physical health. Concerns have been raised regarding the potential dangers of extremely low frequency electromagnetic fields (ELF-EMF) ranging from 3 to 3000 Hz, which are omnipresent in our daily lives and there have been studies about the anxiogenic effects of these fields. Studies conducted in this specific area has revealed that ELF-EMF can have an impact on various brain regions, such as the hippocampus. In conclusion, studies have shown that ELF-EMF can interfere with hippocampus-prefrontal cortex pathway, inducing anxiety behavior. Also, ELF-EMF may initiate anxiety behavior by generating oxidative stress in hypothalamus and hippocampus. Moreover, ELF-EMF may induce anxiety behavior by reducing hippocampus neuroplasticity and increasing the NMDA2_A receptor expression in the hippocampus. Furthermore, supplementation with antioxidants could serve as an effective protective measure against the adverse effects of FLF-FMF in relation to anxiety behavior.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"220-235"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141793980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the biochemical and genotoxic effects of low intensity 2.45GHz microwave exposure on <i>Arabidopsis thaliana</i> plants.","authors":"Mudalige Don Hiranya Jayasanka Senavirathna, Zumulati Maimaiti","doi":"10.1080/15368378.2024.2411629","DOIUrl":"10.1080/15368378.2024.2411629","url":null,"abstract":"<p><p>The electromagnetic waves of 2.45 GHz microwave frequency have become abundant in environments worldwide. This study assessed the short-term impact of low-intensity 2.45 GHz exposure on young <i>Arabidopsis thaliana</i> plants. The plants underwent a 48-hour exposure to continuous wave 2.45 GHz microwaves at a power density of 1.0 ± 0.1 W m^-2. Experiments were conducted inside anechoic chambers. After the microwave exposure samples were subjected to morphological, genotoxicity, pigmentation, and physiochemical analysis. Microwave exposure elevated the levels of photosynthetic pigments, oxidative stress, guaiacol peroxidase activity, and ascorbic peroxidase activity in plants. Conversely, catalase activity decreased. Photosystem efficiency remained unchanged, while non-photochemical quenching increased. Leaf morphological parameters exhibited no significant alterations during this brief exposure period. Notably, despite shifts in physiological parameters and pigmentations, genomic template stability remained unaffected. The findings suggest that the non-thermal effects of microwave exposure influence the photosystem and plant physiology. Research confirmed the existence of non-thermal effects of microwave exposure; however, these effects are within tolerable limits for <i>Arabidopsis thaliana</i> plants.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"303-311"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief survey on human activity recognition using motor imagery of EEG signals.","authors":"Seema Pankaj Mahalungkar, Rahul Shrivastava, Sanjeevkumar Angadi","doi":"10.1080/15368378.2024.2415089","DOIUrl":"10.1080/15368378.2024.2415089","url":null,"abstract":"<p><p>Human being's biological processes and psychological activities are jointly connected to the brain. So, the examination of human activity is more significant for the well-being of humans. There are various models for brain activity detection considering neuroimaging for attaining decreased time requirement, increased control commands, and enhanced accuracy. Motor Imagery (MI)-based Brain-Computer Interface (BCI) systems create a way in which the brain can interact with the environment by processing Electroencephalogram (EEG) signals. Human Activity Recognition (HAR) deals with identifying the physiological activities of human beings based on sensory signals. This survey reviews the different methods available for HAR based on MI-EEG signals. A total of 50 research articles based on HAR from EEG signals are considered in this survey. This survey discusses the challenges faced by various techniques for HAR. Moreover, the papers are assessed considering various parameters, techniques, publication year, performance metrics, utilized tools, employed databases, etc. There were many techniques developed to solve the problem of HAR and they are classified as Machine Learning (ML) and Deep Learning (DL)models. At last, the research gaps and limitations of the techniques were discussed that contribute to developing an effective HAR.</p>","PeriodicalId":50544,"journal":{"name":"Electromagnetic Biology and Medicine","volume":" ","pages":"312-327"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}