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The Role of Quorum Quenching in Medical Application 定量淬火在医疗应用中的作用
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.62
Ghada A. Mohammad, Huda Waleed Hadi
{"title":"The Role of Quorum Quenching in Medical Application","authors":"Ghada A. Mohammad, Huda Waleed Hadi","doi":"10.21931/rb/2024.09.01.62","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.62","url":null,"abstract":"The attempts are continuing in the various fields of life sciences to resolve a big problem, which is the ability\u0000of bacteria to cause pathogenicity for humans, animals, and plants, whether by chemical or biological methods\u0000and in ways that are hoped to be safe. Among these attempts, the control of the Quorum Sensing (QS) mechanism that occurs naturally in bacteria under certain conditions helps to increase the virulence of bacteria,\u0000starting from its ability to adhere and form a biofilm. Then, the tissues are invaded with various enzymes\u0000according to the tissue type, increasing antibiotic resistance. Therefore, the idea came to solve these problems\u0000through a mechanism opposite to the Quorum Quenching (QQ), which lies in the investigation of substances\u0000that can disrupt the QS pathway, whether at the molecular level or the physiological level, as well as benefiting\u0000from different organisms (Prokaryotes or Eukaryotes) that live in the same environment and produce substances that inhibit bacterial signaling molecules. Lastly, the discovery of varying novel QQ agents from extreme environmental bacteria will be most interesting in the future.\u0000Keywords: Quorum sensing, quorum quenching, acyl homoserine lactones, medical application","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140240684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genotypic Detection of Carbapenems Resistance Genes in Acinetobacter baumannii Isolated fromUrinary Tract Infection Patients 从泌尿道感染患者中分离出的鲍曼不动杆菌耐碳苯纳西林基因的基因型检测
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.60
T. Hayder Hasan, Ameer Sadeq Yasir AL-Ethari, S. Ghani Al-Muhanna, Israa Abdul Ameer Al-Kraety
{"title":"Genotypic Detection of Carbapenems Resistance Genes in Acinetobacter baumannii Isolated from\u0000Urinary Tract Infection Patients","authors":"T. Hayder Hasan, Ameer Sadeq Yasir AL-Ethari, S. Ghani Al-Muhanna, Israa Abdul Ameer Al-Kraety","doi":"10.21931/rb/2024.09.01.60","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.60","url":null,"abstract":"Acinetobacter baumannii is a Gram-negative bacterium characterized by its short, round, rod-shaped morphology. It is an opportunistic pathogen that poses a significant threat, particularly to immunocompromised\u0000patients, often those with hospital stays lasting less than 90 days. Between June 2022 and July 2023, 214 urine\u0000samples were collected from individuals suspected of having urinary tract infections (UTIs). These samples\u0000were subjected to antibiotic resistance testing, focusing on detecting specific genes related to carbapenem\u0000resistance, namely blaNDM, blaKPC, and blaVIM.The study's results revealed a notable trend in antibiotic\u0000resistance among the bacterial isolates. Ceftazidime, cefotaxime, and ceftriaxone, commonly used antibiotics\u0000for UTIs, showed a high resistance rate among the tested isolates. This resistance highlights the challenges\u0000healthcare professionals face when treating UTIs caused by Acinetobacter baumannii. On the other hand, the\u0000isolates displayed a comparatively lower resistance rate to imipenem and meropenem, two necessary carbapenem antibiotics. This lower resistance to carbapenems is encouraging as these drugs are often considered\u0000the last line of defense against multidrug-resistant bacterial infections. The presence of carbapenem resistance\u0000genes, such as blaNDM, blaKPC, and blaVIM, in the Acinetobacter baumannii isolates is of particular concern. These genes confer resistance to carbapenem antibiotics, crucial for treating severe infections caused by\u0000multidrug-resistant bacteria. In conclusion, the study aims to study the growth of antibiotic resistance in Acinetobacter baumannii, especially in urinary tract infections in immunocompromised patients with more extended hospital stays. It also highlights the need for Surveys and periodic examinations to detect the spread of\u0000bacteria and their resistance.\u0000Keywords: Carbapenems, UTI, genes, blaNDM, blaKPC, and blaVIM.","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140240869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Composición química y evaluación del sinergismo de la actividad antioxidante de mezclas de los aceites esenciales de Luma chequen (Arrayan) y Citrus maxima (Pomelo). Luma chequen(桃金娘)和 Citrus maxima(葡萄柚)精油混合物的化学成分和抗氧化活性协同作用评估。
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.63
Carla del Carpio-Jiménez, R. G. Gutierrez-Chavez, H. A. Quispe-Dávil, Ciro Tomaylla-Cruz, Mario J. Urrunaga-Ormachea
{"title":"Composición química y evaluación del sinergismo de la actividad antioxidante de mezclas de los aceites esenciales de Luma chequen (Arrayan) y Citrus maxima (Pomelo).","authors":"Carla del Carpio-Jiménez, R. G. Gutierrez-Chavez, H. A. Quispe-Dávil, Ciro Tomaylla-Cruz, Mario J. Urrunaga-Ormachea","doi":"10.21931/rb/2024.09.01.63","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.63","url":null,"abstract":"Los aceites esenciales son componentes bioactivos usados en áreas como la medicina, la farmacia, la cosmética y la industria alimentaria, se emplean como conservantes por sus propiedades antioxidantes. El objetivo\u0000de la presente investigación fue extraer, determinar las propiedades fisicoquímicas y cuantificar por cromatografía de gases/espectrometría de masas los principales componentes de los aceites esenciales de Luma chequen y Citrus maxima, así como evaluar la actividad antioxidante de la mezcla de ambos aceites usando el\u0000método de inhibición del radical ácido 2,2'-azino-bis-3-etilbenzotiazolina-6-sulfónico (ABTS•+). El rendimiento de extracción fue de 0,82% y de 0,95% para Luma chequen y Citrus maxima respectivamente. El pH\u0000fue de 4,5 y 5,5; la densidad fue de 0,877 g/ml y 0,844 g/ml y el índice de refracción fue de 1,4688 y 1,4741\u0000respectivamente. Ambos aceites esenciales presentan alto contenido de monoterpenos siendo el α-pineno\u0000(57,6%) el más abundante para Luma chequen y el limoneno (30,3%) para Citrus maxima. Respecto a la\u0000actividad antioxidante; la inhibición del radical ABTS•+ fue de 49,1% y 93,4% respectivamente, sin embargo,\u0000la mezcla constituida por 50% de aceite esencial de Luma chequen y 50% de aceite esencial de Citrus maxima\u0000presentó un porcentaje de inhibición de 102.8%, evidenciándose sinergismo.\u0000Keywords: Luma chequen, Citrus maxima, antioxidante, monoterpenos, sinergismo","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140236902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluación del desempeño del cultivo de pepino (Cucumis sativus) frente a tres fertilizantes foliares en la parroquia Nuevo Paraíso, Orellana, Ecuador 厄瓜多尔奥雷利亚纳新帕拉伊索教区黄瓜(Cucumis sativus)作物对三种叶面肥的表现评估。
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.11
Lourdes Aguirre-Cobeña, Diego Salguero-Ramos, A. Bonilla-Bonilla, Rodrigo Salazar- López
{"title":"Evaluación del desempeño del cultivo de pepino (Cucumis sativus) frente a tres fertilizantes foliares en la parroquia Nuevo Paraíso, Orellana, Ecuador","authors":"Lourdes Aguirre-Cobeña, Diego Salguero-Ramos, A. Bonilla-Bonilla, Rodrigo Salazar- López","doi":"10.21931/rb/2024.09.01.11","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.11","url":null,"abstract":"La producción de pepino en la región amazónica del Ecuador se ha intensificado en los últimos años, debido a las condiciones climáticas idóneas para este cultivo. En la parroquia Nuevo Paraíso, de la provincia de Orellana se siembra el pepino en pequeñas superficies (>1ha) destinado a consumo local. Los productores han visto la necesidad de aumentar sus rendimientos con la aplicación de fertilizantes foliares. El propósito de este estudio fue comparar el desempeño del cultivo de pepino utilizando tres tipos de fertilizantes foliares comerciales con su respectivo análisis económico. La prueba piloto se realizó en un terreno de 1200 m2 donde se aplicaron los fertilizantes Evergreen (2.5 cm/2L), Metalasote (2.5 cm/2L), Agrostemin (1gr) evaluando la altura de planta, número de hojas y flores, diámetro del tallo y características del fruto a los 22, 37 y 49 días y comparándolo con el testigo. Los hallazgos mostraron que Evergreen es una opción rentable con un costo-beneficio de $1,27 y con mejores características de planta y fruto. Este estudio sugiere la aplicación del fertilizante Evergreen en la etapa de crecimiento y floración del cultivo de pepino dado que representa mejores ingresos por hectárea, un mejor costo-beneficio y mayor porcentaje de ganancia respecto a los demás fertilizantes foliares.\u0000 \u0000Palabras clave: Altura de planta; costo-beneficio; Fertilizantes; Pepino; análisis económico","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140241204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Application of Wheat Farmers to Modern Agriculture Technology Related to Improve Crop Production in Thi-Qar 济加尔地区小麦种植者应用现代农业技术提高作物产量的情况
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.56
Hakeem, S. Abd. AL.Rekibe
{"title":"The Application of Wheat Farmers to Modern Agriculture Technology Related to Improve Crop Production in Thi-Qar","authors":"Hakeem, S. Abd. AL.Rekibe","doi":"10.21931/rb/2024.09.01.56","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.56","url":null,"abstract":"The research aim is to determine the level of application farmers of Modern Agricultural Technology have in\u0000improving wheat crop production in Thi-Qar Province. A multistage sample probability proportionates of size\u0000(PPS) was used to conduct this study. The sample number was (75 farmers from the Qalat Sukkar district, 105\u0000farmers from the AL-Rifai district, 45 farmers from the AL-Shatrah district, and 29 farmers from the AL-Nasr\u0000district) (15% of the total number of farmers) it was 254 farmers. Questionnaire techniques and interviews\u0000with the farmers were adopted to collect the data (March to May 2019). The study has revealed that the highest\u0000percentage (62.6 %) belonged to the medium category in applying modern agricultural technology to improve\u0000wheat crop production. The application level of modern agricultural technology was significant and positive\u0000at a 1% probability level under six variables. Multiple regression analyses have been studied with ten variables: social class, age, Education, Occupation, Farm power, Size of land holding, Family type, Family size,\u0000social participation, and source of information utilized. This research has contributed nine independent variables with significant levels of variation to the extent of the application level of modern agricultural technology\u0000in improving wheat crop production (R2= 0.759). The importance of farmers using modern agricultural technology with the parts (Soil preparation, Planting and crop service, harvesting processes and marketing) was\u0000high according to (72.12, 70.72, and 68.41) respectively. The data were used for analysis: Frequency, percentage, mean, Standard deviation, and multiple regression analysis. According to the result, farmers' application\u0000of modern technology in improving wheat crop production was good. Modern agricultural technology will\u0000reduce costs, increase productivity, and save soil quality. The importance of farmers with the parts (Soil preparation, Planting, crop service, harvesting processes, and marketing) was high according to (72.12, 70.72, and\u000068.41) respectively. Because of this, it is necessary to improve the cultivation of wheat crops to achieve high\u0000productivity and reduce the problems that happen during agricultural production.\u0000Keywords: Technology, Independent variables, Farmers, Harvesting, Size of land holding","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of energy poverty in Andean rural households and design of an efficient cooking solution using biomass 分析安第斯农村家庭的能源贫困状况,设计利用生物物质的高效烹饪解决方案
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.2
Wladimir A Silva-Castelo, Rafael Córdova-Uvidia, Ángel Ordoñez-Echeverria, Miguel Aquino-Arroba
{"title":"Analysis of energy poverty in Andean rural households and design of an efficient cooking solution using biomass","authors":"Wladimir A Silva-Castelo, Rafael Córdova-Uvidia, Ángel Ordoñez-Echeverria, Miguel Aquino-Arroba","doi":"10.21931/rb/2024.09.01.2","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.2","url":null,"abstract":"This work explores energy poverty in the rural households surrounding the Chimborazo Faunal Production Reserve (RPFCH) and proposes an efficient cooking solution using firewood. Energy poverty was evaluated through the multidimensional poverty index (MEPI), including the 10% rule, hidden energy poverty, disproportionate expenses, and a subjective analysis of housing conditions. The research found ten households experiencing moderate energy poverty with a MEPI of 0,1562. An efficient cooking solution was proposed as an improved rocket stove design with an ignition system and forced air at the combustion chamber inlet. This stove utilizes a solar panel and batteries to power the fan. Its thermal efficiency is 13%, including Peltier cells to convert residual heat into DC electricity. The rocket stove's heating capacity is 1,6 kW, which is sufficient for heating a small room and cooking meals. After implementation, a follow-up energy poverty analysis using the same indicators is recommended to evaluate the effectiveness of the proposed solution and its impact on reducing energy poverty.\u0000 \u0000Keywords: energy poverty; rocket stove; thermal efficiency; room heating; Peltier cell; photovoltaic energy.","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140238291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Niveles de Vitamina D en pacientes con y sin Enfermedad Renal Crónica, perfil clínico y epidemiológico: un análisis preeliminiar en un hospital de segundo nivel en quito, Ecuador. 慢性肾病患者和非慢性肾病患者的维生素 D 水平、临床和流行病学概况:厄瓜多尔基多一家二级医院的初步分析。
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.43
André Benítez-Baldassari, Estefanía León-Hernández, Andrea Banegas-Sarmiento, Santiago Aguayo-Moscoso, J. Vélez-Páez
{"title":"Niveles de Vitamina D en pacientes con y sin Enfermedad Renal Crónica, perfil clínico y epidemiológico: un análisis preeliminiar en un hospital de segundo nivel en quito, Ecuador.","authors":"André Benítez-Baldassari, Estefanía León-Hernández, Andrea Banegas-Sarmiento, Santiago Aguayo-Moscoso, J. Vélez-Páez","doi":"10.21931/rb/2024.09.01.43","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.43","url":null,"abstract":"Vitamin D has been associated with different effects unrelated to bone-mineral metabolism, such as its association with arterial hypertension. This study determines the prevalence profile of vitamin D deficiency and\u0000insufficiency in Ecuadorian patients, its epidemiological profile, and its relationship with other diseases such\u0000as arterial hypertension, diabetes mellitus, and chronic kidney disease. This is a pioneering study in Ecuador\u0000of a retrospective type, carried out at the Pablo Arturo Suarez Hospital over 6 months, in which it was found\u0000that the prevalence of vitamin D insufficiency was 28.5% (levels between 21 to 30 ng/ml) and deficiency was\u000057% (levels less than 20 ng/ml); Likewise, we ratify the inverse relationship between vitamin D levels and\u0000age, as well as finding a certain association between vitamin D levels and the presence of arterial hypertension;\u0000while no significant differences were found in its relationship with diabetes mellitus, chronic kidney disease\u0000without the use of renal replacement therapy and the general population.\u0000Keywords: vitamin D, chronic kidney disease, metabolism.","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140237363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anthropometric indicators and their relationship with body fat in obese women. 肥胖女性的人体测量指标及其与体脂的关系。
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.3
Yury Rosales-Ricardo, Vinicio Caiza-Ruiz, Sonia Álvarez-Carrión
{"title":"Anthropometric indicators and their relationship with body fat in obese women.","authors":"Yury Rosales-Ricardo, Vinicio Caiza-Ruiz, Sonia Álvarez-Carrión","doi":"10.21931/rb/2024.09.01.3","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.3","url":null,"abstract":"To determine the anthropometric indicator of best correlation with body fat in women with obesity aged 20 to 59 years. A correlational cross-sectional study was conducted. The percentage of body fat was determined (% GC) and lipid profile (LDL, TG, CT), Body Mass Index (BMI), Hip Waist Index (ICC), Waist Height Index (ICE), Conicity Index (CI), Body Adiposity Index (BSI), Hip Height Index (HSI) and Body Weight by Height Index (BWI). Seven hundred and eighty obese women were selected by random cluster sampling. The correlation of the mean % GC with anthropometric indicators was: BMI:0.697, ICC: 0.661, ECI: 0.910, CI: 0.587, ICadE: 0.323, CAI: 0.578, EICP: 0.549. The lipid profile correlation with anthropometric variables and indices was: LDL (BMI: 0.615, ICC: 0.765, ECI: 0.881, CSI: 0.535, ICadE: 0.588, ECDI: 0.492), TG (BMI: 0.690, ICC: 0.776, ICE: 0.855, CI:0.625, CI: 0.572, CIadE: 0.632, EICP: 0.631) Y TC (BMI: 0.699, ICC: 0.715, ECI: 0.829, CI: 0.601, ACI: 0.609, CIadE: 0.709, EICP: 0.500) High correlation between % GC and Waist Circumference. Waist Height Index had a better correlation with Body Fat.\u0000Keywords: obesity; health; women; nutritional status","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140238408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Histopathological effects of Cryptococcus neoformans on liver and kidney in mice 新生隐球菌对小鼠肝脏和肾脏的组织病理学影响
Bionatura Pub Date : 2024-03-15 DOI: 10.21931/rb/2024.09.01.49
Sara Saad Hussamaldeen Al-Bakir, Dalia Abdalkareem Abdalshaheed
{"title":"Histopathological effects of Cryptococcus neoformans on liver and kidney in mice","authors":"Sara Saad Hussamaldeen Al-Bakir, Dalia Abdalkareem Abdalshaheed","doi":"10.21931/rb/2024.09.01.49","DOIUrl":"https://doi.org/10.21931/rb/2024.09.01.49","url":null,"abstract":"This study provides a brief review of approaches for the detection of histopathological effects of Cryptococcus\u0000neoformans on the liver and kidney in mice that were injected I/P with 105 yeast cells of C. neoformans suspended in 1 ml phosphate-buffered saline at a single dose. After 14 days, the mice were sacrificed, and histopathological sections from the liver and kidney were prepared and stained with Haematoxylin and Eosin by\u0000the P.A.S. method. The results show that the liver was infiltrated with inflammatory cells, primarily mononuclear cells, in the portal. In addition to the activation of Kupffer cells and vacillation of hepatocytes, most\u0000blood vessels were congested. The section of the kidney shows sluffing of epithelia lining tubules and destruction of glomeruli, in addition to infiltration of mononuclear cells. These results suggested that the fungus\u0000invasiveness of mice has substantial effects on vital organs and may lead to death.\u0000Keywords: Cryptococcus neoformans, Hepatic cryptococcal infection, Cryptococcus","PeriodicalId":505112,"journal":{"name":"Bionatura","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140239631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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