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Gematologiya I Transfuziologiya最新文献

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[Immunophenotypic heterogeneity of CD7+CD4-CD8--acute leukemia]. [CD7+CD4-CD8-急性白血病免疫表型异质性]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
I V Abramenko, N I Belous, L M Skliarenko, V A Nadgornaia
{"title":"[Immunophenotypic heterogeneity of CD7+CD4-CD8--acute leukemia].","authors":"I V Abramenko,&nbsp;N I Belous,&nbsp;L M Skliarenko,&nbsp;V A Nadgornaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fourteen cases of lymphoid and myeloid acute leukemia (AL) were studied for expression on blast cells of CD7 antigen, a cell surface marker found early during T lineage differentiation. This heterogenic group of CD7+ CD4-CD8- AL includes distinct cytological subvariants with: myeloid (AML MO, M1, M4, M5) and lymphoid (pre-T-cell) commitment, biphenotypic or mixed lineage AL and AL with minimal signs of blast cell differentiation, which appear not to follow lineage restriction. The latter subset of AL may represent the transformed counterpart of an early stem cell prior to lineage commitment.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"10-3"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Comparative analysis of causes of error in determining blood groups of the ABO system with isohemagglutinating sera and monoclonal antibodies]. 【等血凝血血清与单克隆抗体测定ABO系统血型错误原因的比较分析】。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
G N Zavgorodniĭ, T L Pogodina
{"title":"[Comparative analysis of causes of error in determining blood groups of the ABO system with isohemagglutinating sera and monoclonal antibodies].","authors":"G N Zavgorodniĭ,&nbsp;T L Pogodina","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"42-4"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18563217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Use of a new antimacrophage monoclonal antibody D11 in diagnosis of hemoblastosis]. [一种新的抗巨噬细胞单克隆抗体D11在红细胞增生症诊断中的应用]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
M A Frenkel', N N Tupitsyn, T D Rudinskaia, V S Poltoranina, N B Lebedeva, M A Volkova, G I Kaletin
{"title":"[Use of a new antimacrophage monoclonal antibody D11 in diagnosis of hemoblastosis].","authors":"M A Frenkel',&nbsp;N N Tupitsyn,&nbsp;T D Rudinskaia,&nbsp;V S Poltoranina,&nbsp;N B Lebedeva,&nbsp;M A Volkova,&nbsp;G I Kaletin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Expression of new Mab D11 on blood and bone marrow cells was investigated in 85 hemoblastosis patients. In normals, antigen D11 is expressed on some monocytes and all tissue macrophages. D11 was noted on lymphoblasts of 5 out of 10 cases with B-cell ALL and of 1 case in B-lymphoid blast crisis of chronic myeloid leukemia. In T-ALL, ANLL, non-Hodgkin's lymphomas in leukemization stage, hairy cell leukemia and chronic lymphoid leukemia the cells were nonresponsive to Mab D11. Unlike D11 which have round nuclei, lymphoblasts D11+ have folded nuclei and more pronounced cytoplasmic basophilia. There were both B and myeloid antigens on D11+ blasts. ALL D11+ patients had extramedullary foci, more suppressed granulocytic and thrombocytic components of hemopoiesis, shorter remissions than those with ALL D11-.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"13-6"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Blood lymphocyte ultrastructure in chronic lymphoproliferative diseases]. 慢性淋巴细胞增生性疾病的血淋巴细胞超微结构。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
A A Ushakov, M D Brilliant, S G Potapova, L Iu Tikhonova, I A Vorob'ev
{"title":"[Blood lymphocyte ultrastructure in chronic lymphoproliferative diseases].","authors":"A A Ushakov,&nbsp;M D Brilliant,&nbsp;S G Potapova,&nbsp;L Iu Tikhonova,&nbsp;I A Vorob'ev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors have found that in chronic B-cell lymphoid leukemia and splenic lymphocytoma the proportion of irregular nuclei diminishes, in some patients split nuclei emerged. The proportion of irregular nuclei in lymphocytoma is significantly higher than that in chronic leukemia. The above diseases are characterized by disordered position of mitochondria in relation to cell center and of this center against nuclear invaginations. Microvilli on the cell surface become less numerous. It is suggested that in chronic lymphoproliferative diseases cytoskeleton in tumor cells may undergo structural and functional alterations.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"16-20"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Feasibility of correction of blood aggregation properties in the course of extracorporeal hemosorption in atherosclerosis patients]. [动脉粥样硬化患者体外血液吸收过程中血液聚集特性矫正的可行性]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
K M Balonov, M V Belotserkovskiĭ, K Ia Gurevich, L L Gendel', A Iu Dubikaĭtis
{"title":"[Feasibility of correction of blood aggregation properties in the course of extracorporeal hemosorption in atherosclerosis patients].","authors":"K M Balonov,&nbsp;M V Belotserkovskiĭ,&nbsp;K Ia Gurevich,&nbsp;L L Gendel',&nbsp;A Iu Dubikaĭtis","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Aggregation and rheological properties of blood were evaluated in 20 atherosclerotic patients after cryoplasmosorption. The change of the patients' plasma for extracorporeally modified autoplasma reduced coagulation potential, enhanced fibrinolysis and suppressed anticoagulation systems. Clinical efficacy manifested in decreased frequency and duration of anginal episodes, intensity of intermittent claudication. Biochemically, cholesterol levels and atherogenic index lowering was evident.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"23-5"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Restoration of hematopoiesis following allo- and automyelotransplantation in patients with hemoblastosis]. [造血疾病患者同种异体和自体骨髓移植后造血功能的恢复]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
L S Liubimova, E N Glasko, L P Mendeleeva, A Ali-Pasha, V G Savchenko
{"title":"[Restoration of hematopoiesis following allo- and automyelotransplantation in patients with hemoblastosis].","authors":"L S Liubimova,&nbsp;E N Glasko,&nbsp;L P Mendeleeva,&nbsp;A Ali-Pasha,&nbsp;V G Savchenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The early stages of hemopoiesis repair as indicated by histologic examinations of trephine biopsy specimens (visual assessment and morphometry) are characterized in 39 patients with hemoblastoses, 33 of these with acute leukemia, 4 with chronic myeloleukemia, and 2 with lymphoblastic lymphosarcoma, following transplantation of allogeneic (n = 19), syngeneic (n = 5), and autologous (n = 15) bone marrow after conditioning with cyclophosphamide plus total radiation exposure in 27 patients and myelosan with cyclophosphamide in 12 ones. Hemopoiesis repair was found to be slower after autologous transplantation of bone marrow than after allogeneic transplantation and in patients following conditioning with cyclophosphamide and total irradiation in comparison with those pretreated with myelosan and cyclophosphamide. Patients' age over 25, diagnosis of the disease more than 12 months before transplantation, and variant of leukemia (nonlymphoblastic) were the factors exerting negative influence on the rate of hemopoiesis recovery.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"3-10"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Experience in using plasmapheresis in comprehensive therapy of myelotoxic agranulocytosis in cancer patients]. 【血浆置换在肿瘤患者骨髓毒性粒细胞缺乏症综合治疗中的应用体会】。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
V I Legeza, V I Andriukhin, A G Artemenko, A I Pankst'nov, I D Karev
{"title":"[Experience in using plasmapheresis in comprehensive therapy of myelotoxic agranulocytosis in cancer patients].","authors":"V I Legeza,&nbsp;V I Andriukhin,&nbsp;A G Artemenko,&nbsp;A I Pankst'nov,&nbsp;I D Karev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Plasmapheresis was applied in 10 patients given chemotherapy and radiation treatment for myelotoxic agranulocytosis. After 1-3 sessions the patients improved, recovered hemopoiesis and normal protein metabolism. Of 10 patients 9 survived.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"21-3"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of phorbol ester on the proliferation and differentiation of blast cells from leukemia patients and blast secretion of biologically active products]. [佛波酯对白血病患者母细胞增殖分化及母细胞分泌生物活性产物的影响]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
E R Machiulaĭtene, M V Blagosklonnyĭ, E B Lasunskaia
{"title":"[Effect of phorbol ester on the proliferation and differentiation of blast cells from leukemia patients and blast secretion of biologically active products].","authors":"E R Machiulaĭtene,&nbsp;M V Blagosklonnyĭ,&nbsp;E B Lasunskaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The influence of tetra phorbol diesther (TPA) on primary blast cells of patients with acute leukemia and blastic crises of chronic myelogenous leukemia and the influence of the condition medium (CM) of the primary and TPA-treated blast cells on the proliferation of HL-60 cell line has been studied. The level of interferon-alpha (IFN-alpha) in CM was tested. TPA inhibited proliferation and induced macrophage-like differentiation of primary AML blast cells and these changes were accompanied by modulation of IFN-alpha expression in CM. The effect of blast CM on proliferation of HL-60 was both inhibitory and stimulating and depended on the time of treatment and individual characteristics of patients. It has been shown that the level of IFN-alpha in CM was not correlated with antiproliferative effect of CM. The role of individual differences in capability of primary blast cells to be induced by differentiated agents and the nature of these differences are discussed.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"25-8"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Induction of human platelet aggregation by nerve tissue antigens and immune complexes]. [神经组织抗原和免疫复合物诱导人血小板聚集]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-07-01
L I Matusevich, A B Samal'
{"title":"[Induction of human platelet aggregation by nerve tissue antigens and immune complexes].","authors":"L I Matusevich,&nbsp;A B Samal'","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is shown that antigens of the peripheral nerve and immune complexes (IC) are able to induce platelet aggregation. The highest IC aggregation activity was seen in the excess of the antigens. Specific antiserum had no aggregation capacity, but IC produced in its participation displayed higher aggregation activity than free antigens. The involvement of antigens and IC of the peripheral nerve in impairment of platelet function is suggested.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 4","pages":"29-31"},"PeriodicalIF":0.3,"publicationDate":"1995-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18564487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in the T-cell component in patients with subleukemic myelosis at various stages of the pathologic process]. [亚白血病骨髓病患者病理过程各阶段t细胞成分的变化]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1995-05-01
S A Guseva
{"title":"[Changes in the T-cell component in patients with subleukemic myelosis at various stages of the pathologic process].","authors":"S A Guseva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>T-cell immunity was assessed in 111 patients with subleukemic myelosis. In such patients with large tumor mass and leukemia exacerbation the amount of immunocompetent cells and their functional activity were reduced more prominently. Association of infection and inflammation promoted aggravation of initial immune deficiency.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"40 3","pages":"3-5"},"PeriodicalIF":0.3,"publicationDate":"1995-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18646225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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