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[Subpopulations of peripheral blood neutrophils and lymphocytes in children with immune neutropenia]. [免疫中性粒细胞减少症患儿外周血中性粒细胞和淋巴细胞亚群]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
A M Akk, E A Mamedova, R V Lenskaia, N A Finogenova
{"title":"[Subpopulations of peripheral blood neutrophils and lymphocytes in children with immune neutropenia].","authors":"A M Akk,&nbsp;E A Mamedova,&nbsp;R V Lenskaia,&nbsp;N A Finogenova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Peripheral blood (PB) neutrophils and lymphocytes from 14 patients with immune neutropenia were studied using the technique of rosette-formation in 2 neutrophil fractions with diverse specific density. All the neutropenia cases were divided into 2 groups by phagocytosis completeness in all the PB neutrophil types studied. Patients of group 1 had impaired phagocytosis D-RFN in elevated levels of these cells, autorosette-forming lymphocytes and neutrophils. Patients of group 2 had defective phagocytosis D-RFN and EAC-RFN in combination with extremely high contents of autorosette-forming including early lymphocytes. The above complex of techniques may be used for prediction of the duration and severity of neutropenia which is important for further selective studies into the causes of neutropenia and effective treatment.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"21-4"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19725966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Updated approaches to erythrocyte and platelet transfusions in children]. [儿童红细胞和血小板输注的最新方法]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
V A Agranenko
{"title":"[Updated approaches to erythrocyte and platelet transfusions in children].","authors":"V A Agranenko","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"41-3"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19725976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of acute promyelocytic leukemia in children with all-trans-retinoic acid]. [全反式维甲酸治疗儿童急性早幼粒细胞白血病]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
A A Maschan, N G Klebanova, N V Miakova, O A Tiganova, A M Timakov, E V Samochatova
{"title":"[Treatment of acute promyelocytic leukemia in children with all-trans-retinoic acid].","authors":"A A Maschan,&nbsp;N G Klebanova,&nbsp;N V Miakova,&nbsp;O A Tiganova,&nbsp;A M Timakov,&nbsp;E V Samochatova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"43-5"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19726597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Status of the pediatric oncohematologic service in Russia]. [俄罗斯儿童血液肿瘤服务现状]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
A G Rumiantsev, E B Vladimirskaia
{"title":"[Status of the pediatric oncohematologic service in Russia].","authors":"A G Rumiantsev,&nbsp;E B Vladimirskaia","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In spite of the fact that official statistical data show lower cancer morbidity of pediatric population in Russia than in Europe and USA (9.7 against 13.8 and 13.6, respectively), real cancer incidence may be close to mean incidence in Europe and USA as in Moscow it is 14.8 in boys and 12.0 in girls. Lower numbers in some other regions may be attributable to low standards of cancer diagnosis and inadequate case registration. In Moscow where standards of children's hematological service are high the proportion of some malignancies is the following: hemoblastoses-48.5%, CNS tumors-19.8%, neuroblastoma-8.0%, renal tumors-6.5%, sarcomas of soft tissues and bones-2.4 and 4.6%, respectively. The efficacy of anticancer treatment of children in many regions of Russia is poor, but the situation may be changed for the best by introduction of new approaches developed in the Moscow Research Institute of Pediatric Hematology.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"3-7"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19726802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The interaction of peripheral blood leukocytes with alpha1-acid glycoprotein, its carbohydrate chains and neoglycoconjugates]. [外周血白细胞与α - 1-酸性糖蛋白及其碳水化合物链和新糖缀合物的相互作用]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
S D Shiian, S V Khaĭdukov, A L Pukhal'skiĭ, A P Toptygina, N V Bovin
{"title":"[The interaction of peripheral blood leukocytes with alpha1-acid glycoprotein, its carbohydrate chains and neoglycoconjugates].","authors":"S D Shiian,&nbsp;S V Khaĭdukov,&nbsp;A L Pukhal'skiĭ,&nbsp;A P Toptygina,&nbsp;N V Bovin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The interaction of human peripheral blood leukocytes with alpha 1-acid glycoprotein (AGP), its glycoforms as well as neoglyco-conjugates representing carbohydrate chains of AGP or its fragments was studied by flow cytometry. It was shown that the main target cells for AGP as well as for conjugates of its carbohydrate chains with polyacrylamide (PAA) are monocytes and polymorphonuclear leukocytes but not lymphocytes. The interaction of AGP with monocytes and granulocytes are mediated by its carbohydrate chains: the binding of AGP with cells was inhibited by AGP, AGP oligosaccharides as well as conjugates of oligosaccharides and its fragments with PAA. The data obtained show the existence of monocyte (and granulocyte) receptors which interact with complex type sialooligosaccharides of AGP.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"24-9"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19725972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Alpha-interferon in present-day treatment of myeloma]. [干扰素在骨髓瘤治疗中的应用]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
E A Demina, O M Votiakova
{"title":"[Alpha-interferon in present-day treatment of myeloma].","authors":"E A Demina,&nbsp;O M Votiakova","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"32-6"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19726596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cell composition of umbilical cord blood in complicated and uncomplicated pregnancy]. [复杂妊娠与非复杂妊娠脐带血细胞组成分析]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
I V Alekseev, M D Volynets, E B Vladimirskaia, E Iu Osipova, N V Zamaraeva, A G Rumiantsev
{"title":"[Cell composition of umbilical cord blood in complicated and uncomplicated pregnancy].","authors":"I V Alekseev,&nbsp;M D Volynets,&nbsp;E B Vladimirskaia,&nbsp;E Iu Osipova,&nbsp;N V Zamaraeva,&nbsp;A G Rumiantsev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Possible influence of most frequently encountered types of pathology during pregnancy on the cell composition of umbilical cord blood was studied. These pathologies included: treated iron-deficiency anemia, essential hypertension, threatening spontaneous abortion. A number and proliferative potential of granulocyte-macrophage precursor cells of umbilical cord blood were studied by agar drop-liquid media culture method. It was found that the types of pathology studied do not influence cell composition, number and proliferative potential of granulocyte-macrophage precursor cells from umbilical cord blood. These results show that umbilical cord blood after pathological pregnancy can be considered as a source of transplantable hemopoietic cells.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"16-8"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19725968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
["Cyclosporin dependence" in the treatment of severe aplastic anemia in children]. [“环孢素依赖”治疗儿童重度再生障碍性贫血]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
N Iu Bogacheva, M M Shneĭder, A A Maschan
{"title":"[\"Cyclosporin dependence\" in the treatment of severe aplastic anemia in children].","authors":"N Iu Bogacheva,&nbsp;M M Shneĭder,&nbsp;A A Maschan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cyclosporin A (CA) was used in the treatment of 2 patients with acquired aplastic anemia. Upon reaching hematological remission these children had recurrence consequent to dose lowering or discontinuation of CA. The remission occurred again when full-dose CA treatment was resumed. Slow 2-year decrease in CA dose led to uneventful end of CA treatment without deterioration of blood picture.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"18-21"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19725971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Distribution of hematopoietic stem cells in the mononuclear fraction of human umbilical cord blood]. [造血干细胞在人脐带血单核部分的分布]。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
S V Iurasov, E B Vladimirskaia, M A Moore
{"title":"[Distribution of hematopoietic stem cells in the mononuclear fraction of human umbilical cord blood].","authors":"S V Iurasov,&nbsp;E B Vladimirskaia,&nbsp;M A Moore","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The advances in transplantation of hemopoietic stem cells (HSC) from umbilical human blood (UHB) necessitate introduction of effective methods of HSC isolation and preservation. The studies show that UHB cells remained viable even after several days of storage at room temperature. Density gradients proved effective for isolation of cell precursors from UHB. Most of hemopoietic cell-precursors in UHB have low density (under 1.070 g/ml) which becomes greater with cell maturation.</p>","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"13-6"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19726803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acute promyelocytic leukemia: model of differential therapy]. 急性早幼粒细胞白血病:鉴别治疗模型。
IF 0.3 4区 医学
Gematologiya I Transfuziologiya Pub Date : 1996-03-01
E V Samochatova, A G Rumiantsev
{"title":"[Acute promyelocytic leukemia: model of differential therapy].","authors":"E V Samochatova,&nbsp;A G Rumiantsev","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":50427,"journal":{"name":"Gematologiya I Transfuziologiya","volume":"41 2","pages":"29-32"},"PeriodicalIF":0.3,"publicationDate":"1996-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19725965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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