Ideggyogyaszati Szemle-Clinical Neuroscience最新文献

{"title":"Statistical evaluation of measured biomechanical properties of human brain aneurysm samples.","authors":"Krisztina Brigitta Tóth, András Lengyel, István Nyáry","doi":"10.18071/isz.77.0177","DOIUrl":"https://doi.org/10.18071/isz.77.0177","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>Human brain aneurysms may often prove fatal if not re&shy;cognized in time and treated accordingly. The understanding of development and rupture of aneurysms can significantly be improved by the application of numerical modelling, which in turn, requires the knowledge of mechanical properties of vessel wall. This study aims to identify assumed differences with respect to age, sex, spatial orientation, and rupture by utilizing detailed statistical analysis of uniaxial tensile measurements of human brain aneurysm samples, performed by the authors in a previous project.</p>.</p><p><strong>Methods: </strong><p>At surgery of 42 patients, aneu&shy;rysm fundi were cut distally to the clip. In each case, depending on size, varying number of stripes (altogether 88) were prepared and uniaxial stress-strain measurements were performed. Quantities related to the capacity, energy absorption or stiffness were determined and statistically analysed.</p>.</p><p><strong>Results: </strong><p>The number of specimens in the aneurysm sample was sufficient to establish statistical differences with respect to sex and rupture (p&lt;0.05). No significant differences were detected in orientation, though higher values of stresses and deformations were ob&shy;tained in the circumferential direction com&shy;pared to the meridional direction.&nbsp;</p>.</p><p><strong>Conclusion: </strong><p>Significant differences bet&shy;ween sexes with respect to ultimate deformations were demonstrated according to expectation, and the hypothesis on equality of energy capacity could be supported. Similarity of curves with respect to specimen orientation was also observed and ruptured aneurysm sacs tended to be smaller in size. It seems that differences and trends described in this paper are realistic and need to be applied in numerical modelling.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 5-6","pages":"177-185"},"PeriodicalIF":0.8,"publicationDate":"2024-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lightning strike‑induced cauda equina syndrome: a case report.","authors":"Aysegul Akkan Suzan, Betul Ozenc, Ayse Sahin Gamze, Zeki Odabasi","doi":"10.18071/isz.77.0137","DOIUrl":"https://doi.org/10.18071/isz.77.0137","url":null,"abstract":"<p><p><p>Peripheral nerve injuries after being struck by lightning have been documented. Here, we report a case of cauda equina syndrome induced by lightning. A 27-year-old man presented with numbness, a burning sensation in the saddle region, and increased urinary urgency after being struck by lightning. He had absent Achilles reflexes and paresthesia in the saddle region upon neurological examination, and magnetic resonance imaging of the spine was normal. Electrophysiological studies indicated involvement of bilateral L5, S1, and S2 myotomes and revealed cauda equina lesions.&nbsp;<br>Peripheral nerve injury induced by lightning is rare, and the evaluation of people with neurological complaints using electromyography will help determine the true incidence.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"137-139"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Comparison of pain intensity measurements among patients with low-back pain].","authors":"Zoltán Nagy, Nóra Kiss, Mátyás Szigeti, Judit Áfra, Norbert Lekka, Ferenc Misik, István Mucsi, Péter Banczerowski","doi":"10.18071/isz.77.0131","DOIUrl":"https://doi.org/10.18071/isz.77.0131","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>Pain intensity is the most frequently assessed health domain in clinical studies among patients with low-back pain. Visual analogue scale (VAS) and Numeric rating scale (NRS) have been the mostly used measurement tools for pain intensity. We proposed to correlate these instruments to a generic health-related quality of life measurement tool in order to show the scale with superior clinical relevance.</p>.</p><p><strong>Methods: </strong><p>We used cross-sectional, convenience sampling. 120 patients with chronic low-back pain administered the 29-item Patient Reported Outcomes Measurement Information System Profile with NRS included, and the VAS scale in the National Institute of Mental Health, Neurology and Neurosurgery. We determined the correlation between PROMIS domain T-scores and VAS and NRS scores.</p>.</p><p><strong>Results: </strong><p>We performed Spearman rank correlation test to calculate the correlation coefficient. We found VAS scales measuring pain had weak to moderate correlations with all PROMIS health domains (r = 0.24&ndash;0.55). Therefore, we compared correlation of PROMIS domain scores with PROMIS pain intensity numeric rating scale and VAS scales. PROMIS domains had moderate to strong correlations with pain intensity scale (r = 0.45&ndash;0.71). PROMIS physical function short form [r = &ndash;0.65, 95% CI (&ndash;0.75) &ndash; (&ndash;0.55)] and PROMIS pain interference short form (r = 0.71, 95% CI 0.63 &ndash; 0.79) had the strongest correlation with pain intensity item.</p>.</p><p><strong>Conclusion: </strong><p>NRS has showed greater correlation with PROMIS domain T-scores than VAS scale. This may prove that NRS has greater connection to another health domains, thus it correlated more to health-related quality of life than visual scale. We recommend NRS to use in further clinical studies conducted among patients with low-back pain.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"131-135"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of anesthetic blockade of greater occipital nerve during the withdrawal period of the medication overuse headache treatment.","authors":"Unsal Aysen Mirac, Aydin Tugrul","doi":"10.18071/isz.77.0103","DOIUrl":"https://doi.org/10.18071/isz.77.0103","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>Discontinua&shy;tion of medication still remains a key element in the treatment of medication overuse headache (MOH), but there is no consensus on the withdrawal procedure. We aimed to share the promising results of anesthetic blockade of greater occipital nerve (GON), which can be an alternative to existing treatments during the early withdrawal period of MOH treatment.</p>.</p><p><strong>Methods: </strong><p>This study was conducted using regular electronic medical records and headache diaries of patients diagnosed with MOH and treated with anesthetic GON blockade with 0.5% bupivacaine solution in a specia&shy;lized headache outpatient clinic. A total of 86 patients who developed MOH while being followed up for chronic migraine were included in the study.</p>.</p><p><strong>Results: </strong><p>The treatment schemes for MOH are based on expert consensus and withdrawal strategies are the most challenging part of treatment. In our study, numerical rating scale for headache intensity, overused medication consumption per month, headache frequency (day/month) and the duration of each attack (hour/day) decreased significantly in the first month compared to pre-treatment (p &lt; 0.01).&nbsp;</p>.</p><p><strong>Conclusion: </strong><p>Conclusion &ndash; Our study suggests that GON blockade can be used as a good alternative therapy in the treatment of MOH.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"103-110"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Thrombolysis treatment and multi- disciplinary management of central retinal artery occlusion in comparison with traditional ophthalmological treatment options].","authors":"Szilvia Vajda, Bence Gunda, Krisztina Knézy, Péter Barsi, Csaba Varga, Pál Maurovich-Horvat, Dániel Bereczki, Zsolt Zoltán Nagy","doi":"10.18071/isz.77.0089","DOIUrl":"https://doi.org/10.18071/isz.77.0089","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>The management of central retinal artery occlusion (CRAO) has long been conservative therapy with limited efficacy carried out in ophthalmology departments together with etiolo&shy;gi&shy;cal investigations lacking a standardised protocol. However, CRAO is analogous to ischemic central nervous system stroke and is associated with increased stroke risk, thus, systemic thrombolysis treatment and multidisciplinary management can be beneficial. Since May 2022, at Semmelweis University CRAO patients diagnosed within 4.5 hours are given intravenous thrombolysis therapy and undergo etiologic workup based on current stroke protocols. Here we report our experience with the multidisciplinary, protocol-based management of CRAO in comparison with former non-protocol based ophthalmological conservative treatment.</p>.</p><p><strong>Methods: </strong><p>We reviewed CRAO patients&rsquo; data treated conservatively and with paracentesis within 6 hours at the Department of Ophthalmology between 2013 and 2022 including changes in visual acuity, neurolo&shy;gical and cardiovascular findings compared to those in the thrombolysis project.&nbsp;</p>.</p><p><strong>Results: </strong><p>Of the 78 patients receiving non-protocol care, visual improvement was seen in 37% with natural course, 47% with conservative treatment and 47% with paracentesis. Four patients had significant carotid stenosis (2 underwent endarterectomy), 1 carotid dissection, 6 cardioembolism and 1 giant cell arteritis. Of the 4 patients within 4,5 hours, 3 gave their consent to the clinical trial and were treated with thrombolysis and underwent a full etiological assessment.&nbsp;<br>2 pa&shy;tients had improved visual acuity, 2 pa&shy;tients had significant carotid stenosis and underwent endarterectomy, 1 patient was started on anticoagulation for newly diagnosed atrial fibrillation.</p>.</p><p><strong>Conclusion: </strong><p>CRAO patients presenting within 4,5 hours are rare and more patients are needed in our study to establish the efficacy of thrombolysis. However uniform protocollized evaluation helps identifying embolic sources thus, avoiding further and potentially more serious thromboembolic events.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"89-96"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Middle meningeal artery embolization to treat acute epidural haematoma, case report and literature review].","authors":"Benedek Oláh, Zsolt Csaba Oláh","doi":"10.18071/isz.77.0141","DOIUrl":"https://doi.org/10.18071/isz.77.0141","url":null,"abstract":"<p><p><p>The treatment of acute epidural haematoma is surgery as soon as possible, elimination of the source of bleeding and evacuation of the haematoma. In case of small epidural haematoma, strict neurological and radiological follow-up is necessary. In a significant percentage of cases, open surgery must also be performed within a few days. In case of small epidural haematomas, embolization of the middle meningeal artery is considered as an alternative solution. We review the literature on middle meningeal artery embolization and present our first treatment. Our case report is the first European report about an acute epidural haematoma which was treated by embolization of middle meningeal artery. Our case study is the first report in which a patient was treated with both open surgery and endovascular treatment for acute epidural haematoma within a year.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"141-144"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perineural 5% dextrose versus corticosteroid injection in non-surgical carpal tunnel syndrom treatment.","authors":"Ocek Ozge, Guner Derya","doi":"10.18071/isz.77.0121","DOIUrl":"https://doi.org/10.18071/isz.77.0121","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>We aimed to investigate the difference of clinical and electrophysiological improvement between perineural corticosteroid injection therapy (PCIT) and perineural 5% dextrose injection therapy (5%PDIT) in carpal tunnel syndrome (CTS).</p>.</p><p><strong>Methods: </strong><p>Total of 92 wrists that were diagnosed as mild-to-moderate idiopathic CTS and completed their follow-up were included in our study. The severity of pain, symptom severity and functional status were asses&shy;sed by visual analog scale (VAS) and the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) scores for treatment effectiveness. Randomized wrists were administered PCIT or 5%PDIT accompanied by ultrasound guidance. VAS, BCTQ scores and the electro&shy;physiological study repeated before and after treatment at the 1st and 6th months after perineural injection therapies (PITs) were recorded.</p>.</p><p><strong>Results: </strong><p>Compared with baseline data, within groups there was significant improvement in VAS, BCTQ severity and function scores at 1st and 6th months follow-up (all p &lt; 0.001). Considerable advance were detected in the median sensory nerve conduction velocity (SNCV) when pretreatment values were compared with posttreatment first month in both groups (p = 0.01; p &lt; 0.001, respectively). No significant change occurred in median distal motor latency (DML) values between the 1st and 6th months in the groups (p = 0.095; p = 0.113, respectively). No significant difference was observed bet&shy;ween 5%PDIT and PCIT groups.</p>.</p><p><strong>Conclusion: </strong><p>Clinical and electrophysiologic improvement in CTS began from 1st month after PCIT and 5%PDIT. At the 6th month follow-up of the patients, 5%PDIT and PCIT had similar therapeutic effects. As a result, we can consider the replacement of PCIT with 5%PDIT in mild-to-moderate CTS patients especially in those who are hesitant because of the corticosteroid&rsquo;s adverse effects.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"121-129"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized analysis of pain-weather associations: a pilot study.","authors":"Gábor Tuboly, Gyöngyi Horváth, Kamilla Nagy, Edit Nagy","doi":"10.18071/isz.77.0077","DOIUrl":"https://doi.org/10.18071/isz.77.0077","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background and purpose: &lt;/strong&gt;&lt;p style=\"text-align: justify;\"&gt;It is a wellknown belief that weather can influence human health, including pain sensation. However, the current data are controversial, which might be due to the wide range of interindividual differences. The present study aimed to characterize the individual pain&ndash;weather associations during chronic pain by utilizing several data analytical methods.&lt;/p&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;&lt;p style=\"text-align: justify;\"&gt;The study included 3-3 patients with (P1, P3, and P4) or without (P2, P5, P6) diabetes mellitus and signs of trigeminal neuralgia or low back pain. Subjective pain scores (0&ndash;10) and 12 weather parameters (terrestrial, geomagnetic, and solar) were recorded for one month repeated three times&nbsp;daily. Nonparametric Spearman&rsquo;s correlation&nbsp;(Sp), multiple regression (Mx), and principal&nbsp;component (PCA) analyses were performed&nbsp;to evaluate associations between pain and&nbsp;meteorological factors obtained at the day&nbsp;of recorded pain value, 2 days before and&nbsp;2 days after the recorded pain, and the&nbsp;changes in these parameters (5 &times; 12 parameters). Complex scores were calculated&nbsp;based on the results of these analyses.&lt;/p&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;&lt;p style=\"text-align: justify;\"&gt;While the temperature had the&nbsp;highest effects on the pain levels in most&nbsp;of the participants, huge interindividual&nbsp;dif&shy;ferences in the degree and the direction of the associations between pain and&nbsp;weather parameters could be obtained.&nbsp;The analytic methods also revealed subjectspecific results, and the synthesis of different&nbsp;statistical methods as total scores provided a personalized map for each patient, which&nbsp;showed disparate patterns across the study&nbsp;participants. Thus, Participants 2 and 5 had&nbsp;higher scores for Mx compared to Sp; furthermore, certain factors showed opposite&nbsp;direction in their associations with the pain&nbsp;level depending on the type of analysis (Sp vs&nbsp;Mx). In contrast, P3 had a lower score for Mx&nbsp;compared to Sp, which might suggest a low&nbsp;level of weather sensitivity on the association&nbsp;between the different weather parameters&nbsp;in this subject. Furthermore, participants&nbsp;P4 and P6 had a very high level of weather&nbsp;sensitivity, while P1 had an opposite pattern.&nbsp;Regarding the time point-related effects on&nbsp;the pain level, most patients were sensitive&nbsp;to parameters obtained at the same day or&nbsp;two days before, except the P1 subject, who&nbsp;had the highest sensitivity to weather parameters detected two days after.&lt;/p&gt;.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;&lt;p style=\"text-align: justify;\"&gt;The present study highlights&nbsp;the importance of integrating different&nbsp;data analysis approaches to elucidate the&nbsp;individual connections between pain and&nbsp;most of the weather parameters. In conclusion, complex pe","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"77-87"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuropathic pain and mood disorders in earthquake survivors with peripheral nerve injuries.","authors":"Alaydin Can Halil, Bozdogan Melisa Gul, Paltaci Rumeysa, Arlier Zulfikar, Fidanci Halit, Yildiz Mehmet","doi":"10.18071/isz.77.0097","DOIUrl":"https://doi.org/10.18071/isz.77.0097","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>&nbsp; &nbsp; &nbsp; &nbsp; Natural disasters, such as earthquakes, frequently result in mood disorders among affected individuals. It is established that neuropathic pain arising from traumatic neuropathies is also linked to mood disorders. This study investigates the influence of neuropathic pain on the development of mood disorders in earthquake survivors with peripheral nerve injuries, following the earthquake centered in Kahramanmaraş on February 6, 2023. Additionally, we aim to assess the electro&shy;physiological aspects of neuropathic injuries in these survivors.</p>.</p><p><strong>Methods: </strong><p>The study comprised 46 earth-quake survivors with electrophysiologically confirmed peripheral nerve injuries, with 39 trauma-free survivors serving as the control group. Neuropathic pain, anxiety and depression were assessed using the Douleur Neuropathique 4 (DN4) questionnaire and the Hospital Anxiety and Depression Scale (HADS).</p>.</p><p><strong>Results: </strong><p>Our findings revealed that the ulnar and peroneal nerves were the most commonly injured structures. Among the survivors with peripheral nerve injury, 31 out of 46 (67%) were found to experience neuropathic pain. Furthermore, plexopathy and multiple extremity injuries were associated with more severe neuropathic pain. However, there was no significant difference in anxiety and depression scores between the two groups and neuropathic pain was found to have no independent effect.</p>.</p><p><strong>Conclusion: </strong><p>The study indicates that the intensity of neuropathic pain varies based on the localization and distribution of peripheral nerve injuries. However, the presence of peripheral nerve damage or neuropathic pain was not directly associated with HADS scores, suggesting that mood disorders following disasters may have multifactorial causes beyond physical trauma.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"97-102"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and reliability of the Turkish version of the Informant Assessment of Geriatric Delirium Scale.","authors":"Buket Celik, Ozlem Bilik, Zeynep Deveci Koçbilek, Hale Turhan Damar, Didem Öz, Zeynep Denizmen","doi":"10.18071/isz.77.0111","DOIUrl":"https://doi.org/10.18071/isz.77.0111","url":null,"abstract":"<p><strong>Background and purpose: </strong><p>Delirium is a common complication developing in el&shy;der&shy;ly patients. Therefore, it is important to diagnose delirium earlier. Family caregivers&nbsp;play an active role in early diagnosis of de&shy;lirium and build a bridge between health pro&shy;fessionals and patients. The purpose of this research was to achieve the validity and reliability of the Turkish version of the Informant Assessment of Geriatric Delirium Scale (I-AGeD).</p>.</p><p><strong>Methods: </strong><p>This is a methodological study. The sample comprised 125 caregivers ac&shy;cepting to participate in the study and offering care to older patients with hip fracture aged &ge;60 years. Data were gathered preoperatively and on postoperative days 0, 1 and 2. After achieving the linguistic and content validity of the scale, the known-groups comparison was used to achieve its construct validity. The ROC curve analysis was made to determine the sensitivity and specificity of the scale. Item-total correlations, item analysis based on the difference between the upper 27% and lower 27%, Kuder&ndash;Richardson 20 (KR-20) coefficient and parallel forms reliability with the NEECHAM Confusion Scale were adapted to assess discriminant indices of the items in the I-AGeD.</p>.</p><p><strong>Results: </strong><p>The item-total correlation coeffi&shy;cients of the scale ranged from 0.54 to 0.89 and KR-20 coefficient ranged from 0.09 to 0.91 depending on the measurement times. According to the ROC curve analysis, the sensitivity and specificity of the scale were &ge; 91% and &ge; 96% respectively. The parallel forms reliability analysis showed a highly significant, strong negative relation at each measurement between the I-AGeD and the NEECHAM Confusion Scale.&nbsp;</p>.</p><p><strong>Conclusion: </strong><p>The I-AGeD is valid and reliable to diagnose delirium in older Turkish patients in perioperative processes.</p>.</p>","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"77 3-4","pages":"111-119"},"PeriodicalIF":0.8,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}