Journal of Clinical Pediatric Dentistry最新文献

{"title":"Effectiveness of a needle-free local anesthetic technique compared to the traditional syringe technique for the restoration of young permanent molars: a single-blind randomized clinical trial.","authors":"Nassreen H Albar, Prabhadevi C Maganur, Areej Ali Hasan Alsaeedi, Basmah Hakam Ali Mahdi, Shroog Ali Almasoudi, Suman Panda, Ahad Hasan M Gharawi, Hind Taher Modrba, Reem Hassan Kelani, Lamis Yahya Muthaffar, Mohammed B Hakami, Satish Vishwanathaiah","doi":"10.22514/jocpd.2024.131","DOIUrl":"10.22514/jocpd.2024.131","url":null,"abstract":"<p><p>The sensation of pain can elevate anxiety levels, establishing a cyclical pattern that may result in the avoidance or premature termination of dental procedures. Previous endeavors employing various methods and products have produced varied outcomes. Jet injection systems, employing high pressure and velocity to deliver anesthesia without needles, offer a non-invasive option for local anesthesia administration. To assess and measure pain perception levels in a pediatric population during the restoration of young permanent teeth, comparing a needle-free injection system with the traditional dental needle method. Sixty participants with young permanent first molars requiring indirect pulp capping were enrolled, all under the care of a single operator. A simple randomization method was employed, utilizing sequentially numbered, opaque, sealed envelopes to allocate participants into two intervention groups: Group 1 and Group 2. Group 1 received traditional needle syringe anesthesia, while Group 2 received the needle-less injection system, Injex (INJEX Pharma AG, Germany). Following topical anesthesia application, local anesthesia was administered, and indirect pulp capping was performed. The Face, Legs, Activity, Cry, Consolability Scale (FLACC), Wong-Baker Scale, Time of local anesthesia (LA) Administration, Frankl Behavior Rating Scale (FBRS), and Pulse rate were evaluated and recorded at various intervals. The needle-less injection system required approximately 26.2 seconds for anesthesia administration, significantly less time than the traditional syringe (<i>p</i> < 0.001). FBRS score analysis revealed no significant differences between groups at all intervals. FLACC score analysis during anesthesia administration indicated lower scores in the needle-free injection group (<i>p</i> < 0.001). Evaluation of Wong Baker Scale (WBS) scores showed higher values in the traditional syringe needle group (<i>p</i> < 0.05). Using the Injex system presents a promising alternative for dental anesthesia administration, enhancing patient comfort and alleviating fear associated with traditional injections.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"107-116"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Criteria for early diagnosis of congenitally missing second premolars based on the calcification grades of other permanent posterior teeth: a retrospective study.","authors":"Elif Sifil Kapicioglu, Deniz Basaran, Meltem Bakkal","doi":"10.22514/jocpd.2024.130","DOIUrl":"10.22514/jocpd.2024.130","url":null,"abstract":"<p><p>Diagnosing congenitally missing second premolars (SPs) in early childhood is challenging due to variations in their calcification ages. In this study, we investigated the correlation between calcification grades of SPs and other permanent posterior teeth to aid clinicians in the early diagnosis of congenitally missing SPs. This cohort study retrospectively evaluated 6813 images from 9261 panoramic image records of children aged 42-78 months. The Nolla method was used to score calcification grades of first and SP and first and second permanent molars. Images were divided into 6 subgroups based on age with six-month intervals, and average calcification grades of teeth were analyzed by gender and categorized. The calcification grades of these relevant teeth were separately analyzed, specifically for Grade 0 and Grade 1 for SPs. Gender-based analysis revealed statistically significant differences in the calcification grades of 4 first premolars, 4 permanent first molars, and 2 permanent second molars. However, these differences were not significant for all 4 SPs and teeth numbered 17 and 27 between genders. Generally, Nolla grades were higher in girls compared to boys, except for all 4 SPs and tooth numbered 46. Furthermore, higher Nolla grades were observed in older age groups, which was consistent with expectations. The variability in calcification grades of SPs highlights the importance of understanding the calcification grades of other permanent teeth, which are more clearly visible on radiological images of young children. This knowledge could help clinicians in assessing the dental maturity of pediatric patients and facilitate early diagnosis of congenitally missing teeth.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"101-106"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The correlation between dental caries and dermatoglyphics: a systematic review and meta-analysis.","authors":"Heqian Wang, Jingjing Yan, Wubin Ouyang, Xiaoxuan Xu, Chenkai Lan, Shu Ouyang, Dalei Sun","doi":"10.22514/jocpd.2024.125","DOIUrl":"10.22514/jocpd.2024.125","url":null,"abstract":"<p><p>Here, we used a meta-analysis approach to systematically evaluate the correlation between dental caries and dermatoglyphics. To identify findings relating to the association between dental caries and dermatoglyphics, a methodical literature search was conducted in the PubMed, Embase, Cochrane Library, and Web of Science databases from inception to August 2023. Data analysis was performed using RevMan 5.3 and Stata 15.0 software, combining odds ratios (ORs) and 95% confidence intervals (CIs). A total of eight studies were included, comprising 1563 participants, with 883 in the dental caries group and 680 in the caries-free group. The distribution of arches, loops and whorls between the dental caries group and the caries-free group did not differ significantly. Except for an observed statistical significance in the distribution of arches by study type (<i>p</i> = 0.02), there were no significant differences between the other subgroups. The occurrence rate of whorls was higher in the dental caries group than in the healthy group among female participants, while the distribution of loops was less frequent. Current evidence shows that in the female population, caries and dermatoglyphics were associated, however, in the overall population, the distribution of arches, loops and whorls did not correlate significantly with dental caries, according to this meta-analysis.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"45-58"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical indications for the diagnosis and treatment of functional posterior crossbite in pediatric population: a narrative review with clinical description.","authors":"Antonino Lo Giudice, Alessandro Polizzi, Rosalia Leonardi, Gaetano Isola","doi":"10.22514/jocpd.2024.123","DOIUrl":"10.22514/jocpd.2024.123","url":null,"abstract":"<p><p>The present manuscript aims to provide an updated overview of the clinical management of functional posterior crossbite (FPXB) in growing subjects which can be helpful for orthodontists and pediatric dentists in daily practice. Database searches were performed until December 2023 to evaluate the published literature on the topic. The most pertinent articles were chosen for the review from the retrieved articles. No restrictions regarding the year or language of publication were applied. Additional studies were included by manually searching the references of the included studies. The manuscript has been structured for a narrative purpose. Although there is evidence of spontaneous correction in the transition from deciduous to mixed dentition, the literature suggests initiating the treatment early to increase the success rate. Early treatment involves reducing the risk for potential temporomandibular disorders and adaptations at the level of skeletal, dental, and muscle components. Recent advancements in tridimensionali (3D) imaging systems can also help define the appropriate treatment time case-by-case. Considering the prevalence and the multiple etiological factors involved in the development of FPXB in the pediatric population, orthodontists and pediatric dentists should decide the treatment time for this condition with a careful evaluation of the risk/benefit ratio.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"12-28"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical and mechanical characterizations of experimental pit and fissure sealants based on bioactive glasses.","authors":"Aftab Ahmed Khan, Abdulaziz Abdullah Al-Khureif, Manal Al-Mutairi, Ibrahim Al-Majed, Sanam Aftab","doi":"10.22514/jocpd.2024.127","DOIUrl":"10.22514/jocpd.2024.127","url":null,"abstract":"<p><p>Fissure sealants commonly exhibit weak mechanical and physical properties, potentially compromising their effectiveness in preventing dental caries. Therefore, this laboratory study aimed to synthesize and characterize experimental pit and fissure sealants in comparison with a commercially available sealant. Three different formulations of experimental pit and fissure sealing materials were synthesized using a blend of bisphenol A-glycidyl methacrylate (Bis-GMA) and triethylene glycol dimethacrylate (TEGDMA) monomers. The resin composition encompassed 70 wt.%, with 30 wt.% fillers comprising 10 wt.% silica in each composition, while 20 wt.% bioactive glasses. Specifically, group G1 employed Biomin F powder, group G2 utilized Biomin C powder, and group G3 incorporated S53P4 powder. The control group (GC) was a commercially available pit and fissure sealant (Seal-Rite). Ten disk-shaped specimens from each study group were fabricated (n = 10/group). The surface roughness, water contact angle, nanohardness (nH), elastic modulus (EM), water solubility and sorption were statistically evaluated using a one-way analysis of variance (<i>p</i> < 0.05). The surface roughness of the G1 & G2 groups and the water contact angle of G1, G2 & G3 groups were significantly lower compared to the control group (<i>p</i> < 0.05). However, nH, EM, water solubility, and sorption were notably higher in the control group compared to the experimental groups, except G1, which exhibited no significant difference from the control group (<i>p</i> > 0.05). The inclusion of micron-sized Biomin F powder in the experimental Bis-GMA/TEGDMA resin formulation demonstrated advantageous effects in reducing surface roughness and forming a lower contact angle without compromising the mechanical attributes.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"69-77"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of stress amongst different hierarchies of paediatric dental providers.","authors":"Ateet Kakti, Saleh Atallah Albalawi, Fahad Abdullah Fallatah, Moaz Talal Almalki, Ahmed Abdullah Alzahrani, Abdulrahman Abdulmohsen Alsaif, Marco Cicciù, Giuseppe Minervini","doi":"10.22514/jocpd.2024.126","DOIUrl":"10.22514/jocpd.2024.126","url":null,"abstract":"<p><p>Stress, a state of mental or emotional strain or tension brought on by challenging or demanding events might hamper a dentist's ability to react quickly and prudently. Their ability to deal with difficult patients may also be compromised, especially when dealing with frightened or anxious people. The main goal of this study was to survey a wide range of dental professionals from different backgrounds, including undergraduates, general practitioners and specialists, and determine how much stress each group was experiencing and how it affected both the participants and the treated patients. A sample size of an estimated 300 participants (defined by a 95% confidence interval and a 5% margin of error) was found to be sufficient for this investigation. About 178 responses were received to the 300 Google Forms questions, a response percentage of 59.3%. Of those surveyed, 77% had work experience ranging from zero to five years. Women made up 30% of the population, while men made up 70%. Furthermore, the patient-to-dentist ratio was neither a significant worry nor a source of stress because the majority of dentists saw between 0 and 10 patients per month. General dentists and specialists treated the patients with higher awareness, in-depth understanding and care than undergraduates did because they frequently reported having less experience than the other categories in this study did. The fact that a sizable majority of the respondents had between 0 and 5 years of experience further explains the high stress levels. High anxiety levels were present among dental undergraduates, highlighting the necessity of stress management instruction and support services in training programmes.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"59-68"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142629933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex differences in craniofacial parameters of children and adolescents: a comparative study with the maturation of cervical vertebrae using a cephalometric method.","authors":"Tianxin Gu, Shiyong Zhang, ChuQiao Xiao, Shoushan Hu, Xin Xiong","doi":"10.22514/jocpd.2024.129","DOIUrl":"10.22514/jocpd.2024.129","url":null,"abstract":"<p><p>This study aimed to investigate sex differences in craniomaxillofacial parameters in children and adolescents. Lateral cephalograms were obtained from 340 subjects (141 male, 199 female) aged 6 to 18 years, and their craniofacial characteristics and cervical vertebral maturity were assessed using the quantitative cervical vertebral maturity (QCVM) method. Age-based stratified analyses on craniofacial parameters and further comparison in QCVM Ⅲ subjects were performed. Among all analyses, male subjects had significantly greater value than females in sex-different parameters except for facial convexity. The overall group had 17 sex-different parameters (ramus height, anterior facial height (AFH), posterior facial height (PFH), upper anterior facial height (UAFH), lower anterior facial height (LAFH), anterior cranial base length, posterior cranial base length, facial convexity, upper lip length, upper lip thickness, lower lip thickness, soft tissue chin thickness, nasion of soft tissue-subnasale (N'-Sn), subnasale-menton of soft tissue (Sn-Me'), subnasale-stomion inferius (Sn-Sto)). The <12 years old group showed 6 significant sex differences (AFH, LAFH, lower lip protrusion, lower lip thickness, N'-Sn, Sn-Me'). While the ≥12 years old group occurred two more parameters (mandibular body length, AFH/PFH) than the overall group. 12 cephalometric parameters had significant sex differences among QCMV III patients. After age adjustment, the number of sex-different parameters only increased in soft tissue. Craniofacial characteristics and cervical vertebrae maturation of the youngsters exhibited significant sex differences. Though females reached an earlier cervical vertebral maturation, they still had smaller craniofacial linear features. Sex differences should be taken into account in developing reference standards for cephalometric measurements and treatment planning in the clinic.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"89-100"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Co-Mask R-CNN: collaborative learning-based method for tooth instance segmentation.","authors":"Chen Wang, Jingyu Yang, Hongzhi Liu, Peng Yu, Xijun Jiang, Ruijun Liu","doi":"10.22514/jocpd.2024.136","DOIUrl":"10.22514/jocpd.2024.136","url":null,"abstract":"<p><p>Traditional tooth image analysis methods primarily focus on feature extraction from individual images, often overlooking critical tooth shape and position information. This paper presents a novel computer-aided diagnosis method, Collaborative learning with Mask Region-based Convolutional Neural Network (Co-Mask R-CNN), designed to enhance tooth image analysis by leveraging the integration of complementary information. First, image enhancement is employed to generate an edge-enhanced tooth edge image. Then, a collaborative learning strategy combined with Mask R-CNN is introduced, where the original and edge images are input simultaneously, and a two-stream encoder extracts feature maps from complementary images. By utilizing an attention mechanism, the output features from the two branches are dynamically fused, quantifying the relative importance of the two complementary images at different spatial positions. Finally, the fused feature map is utilized for tooth instance segmentation. Extensive experiments are conducted using a proprietary dataset to evaluate the effectiveness of Co-Mask R-CNN, and the results are compared against those of an alternative segmentation network. The results demonstrate that Co-Mask R-CNN outperforms the other networks in terms of both segmentation accuracy and robustness. Consequently, this method holds considerable promise for providing medical professionals with precise tooth segmentation results, establishing a reliable foundation for subsequent tooth disease diagnosis and treatment.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"161-172"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Type of insurance coverage and dental sealants among US children: findings from the National Survey of Children's Health.","authors":"Lina Bahanan","doi":"10.22514/jocpd.2024.138","DOIUrl":"10.22514/jocpd.2024.138","url":null,"abstract":"<p><p>Access to preventive dental services, such as dental sealants, varies based on several factors, including insurance coverage. The aim of this study was to examine the association between different types of insurance and dental sealant placement among US children. Data from the National Survey of Children Health (NSCH) cycle 2018 was analyzed. The sample size comprised 18,012 children aged 4-14 years. The main outcome was dental sealant placement in the past year (yes/no). The primary predictor was the type of insurance (public, private, both public and private, and uninsured). Bivariate and adjusted multivariate analysis was carried out to estimate weighted prevalence and adjusted odds ratios using SAS 9.4. The adjusted multivariate results showed that dental sealant use was the lowest among uninsured children compared to publicly insured children, followed by privately insured children, and finally mixed insured (public and private) children (adjusted odds ratio (AOR): 0.70; 95% confidence interval (CI): 0.57-0.86, AOR: 0.79; 95% CI: 0.54-1.14, AOR: 0.57; 95% CI: 0.40-0.82, respectively). In conclusion, privately insured, mixed insured, and uninsured children had lower odds of dental sealant use compared to publicly insured children. There was a significant variation in the accessibility of dental sealants among US children based on their insurance coverage. Despite these disparities, every child should have access to dental sealants, regardless of insurance status.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"181-186"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta-analysis: effects of adenoidectomy/tonsillectomy on pediatric maxillary growth development.","authors":"Ling Xu, Yingfei Zhang","doi":"10.22514/jocpd.2024.124","DOIUrl":"10.22514/jocpd.2024.124","url":null,"abstract":"<p><p>Quantitative analysis of adenoid size plays a pivotal role in experimental research, and imaging examinations are extensively employed for this purpose. This study aims to investigate the impact of adenoidectomy/tonsillectomy on the maxillary growth and respiratory outcomes of children. A comprehensive systematic search was conducted across multiple databases, including PubMed, Web of Science and Scopus, utilizing the following keywords: \"gland resection\", \"tonsillectomy\", \"mouth breathing\", \"airway obstruction\", \"low ventilation\", \"obstructive sleep apnea (OSA) syndrome\" and \"dental maxillary growth\" in articles published between January 2000 and April 2022. The eligibility criteria encompassed studies with a well-defined research question, appropriate sample size and reporting of pertinent cephalometric indices. The risk of bias was assessed using the Cochrane Risk of Bias tool. Heterogeneity between studies was evaluated using the Q test and <i>I</i>² statistics. Based on the meta-analysis of six studies, the odds ratio (OR) values for the influence of adenoidectomy/tonsillectomy on nasal line-nasion-sella line (NL-NSL) and mandibular line-nasion-sella line (ML-NSL) in children's maxillary growth were -0.84 and 0.58, respectively, with 95% confidence intervals (CI) of (-1.08, -0.61) and (0.34, 0.81). No heterogeneity was observed between studies (<i>I</i>² = 0.00% for both). In five studies, the OR values for the influence of adenoidectomy/tonsillectomy on children's maxillary growth angle formed by the sella-nasion line and line N-point A (SNA), and angle formed by the sella-nasion line and line N-point B (SNB) were -0.30 and -0.31, respectively, with 95% CI of (-0.55, -0.06) and (-0.56, -0.07). No heterogeneity was observed among studies (<i>I</i>² = 0.00% for both). The study indicated that adenoidectomy/tonsillectomy has a positive impact on the maxillary growth and respiratory issues in children.</p>","PeriodicalId":50235,"journal":{"name":"Journal of Clinical Pediatric Dentistry","volume":"48 6","pages":"29-44"},"PeriodicalIF":1.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}