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[Pathophysiology of immobilization osteoporosis.] [固定骨质疏松的病理生理学]
Clinical calcium Pub Date : 2017-01-01
Kunitaka Menuki, Akinori Sakai
{"title":"[Pathophysiology of immobilization osteoporosis.]","authors":"Kunitaka Menuki, Akinori Sakai","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Enhancement of bone resorption and suppression of bone formation in response to reduced mechanical stress cause rapid bone loss. pharmacotherapy for immobilization osteoporosis in motor paralysis and long-term bedrest is effective therapy. Early intervention for rapid bone loss is important for immobilization osteoporosis.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"31-37"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effects of jumping exercise on bones.] [跳跃运动对骨骼的影响]
Clinical calcium Pub Date : 2017-01-01
Yoshihisa Umemura
{"title":"[The effects of jumping exercise on bones.]","authors":"Yoshihisa Umemura","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Strain rate and strain magnitude are important factors when considering osteogenic response to the bone strain imposed by mechanical stress. Jumping is a high-impact exercise that includes these factors. Ten to twenty jumping repetitions per day can increase bone mass and strength. However, the returns diminish with more than ten jumping repetitions because mechanosensitivity declines. Jumping exercise increases bone strength and bone diameters in particular. Although jump training is not suitable for older people, jump training could be an effective tool to prevent osteopenia in younger age groups.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"67-72"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Atypical femoral fracture and Bisphosphonate.] 非典型股骨骨折和双膦酸盐。
Clinical calcium Pub Date : 2017-01-01
Noriaki Yamamoto
{"title":"[Atypical femoral fracture and Bisphosphonate.]","authors":"Noriaki Yamamoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bisphosphonate therapy had been spread widely in osteoporosis patients, atypical femoral fractures(AFF)were reported in these patients as the unusual effects of bisphosphonate treatment. The pathogenesis of AFF was considered to be an over suppression of bone turnover by bisphosphonate. However recent studies indicated other factors related to AFF initiation. Further studies are required to clarify the mechanism of AFF in order to resolve this adverse events in osteoporosis clinic.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 2","pages":"233-238"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of exercise and sports on musculoskeletal health in the elderly.] [运动对老年人肌肉骨骼健康的影响。]
Clinical calcium Pub Date : 2017-01-01
Atsushi Harada
{"title":"[The effect of exercise and sports on musculoskeletal health in the elderly.]","authors":"Atsushi Harada","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There is insufficient information on the effect of exercise and sports on musculoskeletal health in the elderly. Although the effects of sports are still unclear, the effects of exercise could be significant. For example, exercise improves osteoporosis by increasing bone mineral density and ameliorates sarcopenia by increasing muscle mass, muscular strength, and walking speed. As a result, fall risk is reduced and fracture risk is also likely to improve. Tai Chi is reportedly effective for joint pain and stiffness, and may improve symptoms of osteoarthritis.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"117-123"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effects of exercise and sports activities on bone and joint morbidities.] [运动和体育活动对骨骼和关节疾病的影响]
Clinical calcium Pub Date : 2017-01-01
Shinichi Yoshiya
{"title":"[The effects of exercise and sports activities on bone and joint morbidities.]","authors":"Shinichi Yoshiya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Exercise and sports activities can afford mechanical stimuli to the bone and joint tissues which are required to maintain the tissue properties. Moreover, physical exercise is an important part of the management of bone and joint morbidities such as osteoporosis, osteoarthritis, and low back pain. On the other hand, excessive mechanical load involved in exercise and sports activities can be harmful potentially causing overuse injuries of the musculoskeletal tissues. Especially, safety margin for the amount of acceptable mechanical stress is narrow in the elderly due to preexisting musculoskeletal problems. Preparticipation medical checkup and construction of appropriate exercise program based on the physical assessment are mandatory to prevent overload applied to the bone and joint tissues.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"39-43"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Topics for clinical research.] 【临床研究课题】
Clinical calcium Pub Date : 2017-01-01
Seiji Fukumoto
{"title":"[Topics for clinical research.]","authors":"Seiji Fukumoto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Results from phase 3 study of a new drug along with effects of longer duration of a currently used drug for osteoporosis were presented. While there were several papers concerning odanacatib, the clinical development of this drug was announced to be terminated just before the meeting. In addition, low treatment rate for patients with osteoporosis because of fear for rare adverse events was emphasized to be a crisis in the treatment of osteoporosis. Finally, a new treatment for hypophosphatemic diseases was introduced. There are many clinically important topics in this meeting.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"133-137"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The study for effect of running on bone.] [跑步对骨骼影响的研究]
Clinical calcium Pub Date : 2017-01-01
Naomi Omi
{"title":"[The study for effect of running on bone.]","authors":"Naomi Omi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Running-exercise is a weight-bearing-exercise. Power of an effect for running-exercise might be different by exercise intensity, running speed, and duration time. In general, running-exercise could be effective on bone. However, in case of Female Athlete Triad, under the condition of low energy availability running-exercise should not be effective positively for bone. Influence of appropriate mechanical stress, stimulate calcium absorption, and so on through running-exercise could be effective positively for bone.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"55-65"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The Effects of Exercising in Childhood on Bone Health.] 儿童时期运动对骨骼健康的影响
Clinical calcium Pub Date : 2017-01-01
Kazuhiro Imai, Jun Iwamoto, Suguru Torii, Atsushi Masujima
{"title":"[The Effects of Exercising in Childhood on Bone Health.]","authors":"Kazuhiro Imai, Jun Iwamoto, Suguru Torii, Atsushi Masujima","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In contemporary Japan, there is a polarizing trend in children who exercise more than 1,800 minutes a week and those who exercise less than 60 minutes a week. Quite a lot of girls in particular hate exercise,and therefore they don't get enough of it. Osteoporosis is a preventable disease from childhood. It is crucial for girls to exercise and to provide appropriate stimulation to bones before menarche, which increases bone mineral content. Exercise and sports in childhood are characterized as the ways to the lifelong prevention strategies against osteoporosis and fractures. It is hoped that all children practice appropriate exercise program based on scientific evidence to promote bone health. In this review article, the effects of exercising in childhood on bone health, and the points to be noted regarding childhood sports are described.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145350929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Efficacy and safety of long-term bisphosphonate treatment for osteoporosis.] [长期双膦酸盐治疗骨质疏松症的疗效和安全性]
Clinical calcium Pub Date : 2017-01-01
Takami Miki
{"title":"[Efficacy and safety of long-term bisphosphonate treatment for osteoporosis.]","authors":"Takami Miki","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Bisphosphonates can be administered by various ways, and number of patient under bisphosphonate treatment for longer periods is increasing. As bisphosphonates remain inside body for long period, and continue to suppress bone resorption, careful observation is required to these patients. Recent reports show 5-10 year-treatment is safe and keep reduction of the fracture risk without increase of the adverse effects. On the other hand, interruption of the treatment of 2-5 years does not reduce the effectiveness for bone turnover, bone mineral density, and/or fractures. Therefore, bisphosphonate treatment can be interrupted after longer periods of treatment except patients with high fracture risks. We need more scientific date for the prevention of atypical fracture, and reasonable levels of bone turnover and periods of the suppression.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 2","pages":"239-246"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of exercise and sports activity on bone health during the period of adolescence to young adulthood.] [青少年至青年时期运动和体育活动对骨骼健康的影响]
Clinical calcium Pub Date : 2017-01-01
Takeru Kato
{"title":"[Effect of exercise and sports activity on bone health during the period of adolescence to young adulthood.]","authors":"Takeru Kato","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Physical activity may play an important role in maximizing bone mass during adolescence to young adulthood and may have long-lasting benefits on bone health. Because peak bone mass is thought to be attained by the end of the third decade, the early adult years may be the final opportunity for its augmentation. High-impact weight-bearing exercise during youth may provide lifelong benefits in terms of bone mineral content, structure and strength, and consequently reduce fracture risk. Weight-bearing exercise in youth affects bone, and these effects may be preserved as BMC, geometric and structural advantages even after 40 years. In order to evaluate the bone strength enhanced by the exercise and sporting activity, not only measuring the BMD by DXA but also the cross sectional geometric bone analysis may clarify the further contributions.</p>","PeriodicalId":502100,"journal":{"name":"Clinical calcium","volume":"27 1","pages":"101-106"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145351184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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