{"title":"Robotic transfer of 2D materials comes of age","authors":"Timothy John Booth, Peter Bøggild","doi":"10.1038/s44286-025-00221-x","DOIUrl":"10.1038/s44286-025-00221-x","url":null,"abstract":"The transfer of 2D materials from growth to device substrates has hampered their scalability. Now, a robotic, solvent-free process promises clean, high-yield and wafer-scale integration.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"292-293"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Level up the researcher in automated laboratories","authors":"Jason Hein","doi":"10.1038/s44286-025-00220-y","DOIUrl":"10.1038/s44286-025-00220-y","url":null,"abstract":"The true promise of automation lies not in throughput, but in the new kind of researcher it enables, argues Jason Hein.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"276-276"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Mesbah, Robert Wood, Wei Gao, Timothy Noël, Andrew I. Cooper, Dawn Tilbury, S. Joe Qin
{"title":"Sensing connections in automation, control and robotics","authors":"Ali Mesbah, Robert Wood, Wei Gao, Timothy Noël, Andrew I. Cooper, Dawn Tilbury, S. Joe Qin","doi":"10.1038/s44286-025-00226-6","DOIUrl":"10.1038/s44286-025-00226-6","url":null,"abstract":"For the May Focus issue of Nature Chemical Engineering, we asked seven leading researchers working across automation, control and robotics to share their perspectives on a facet of their field that they believe will drive transformative progress within these interconnected domains.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"281-284"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beyond TRY in biomanufacturing scale-up","authors":"Zizhao Wu, Peng Xu","doi":"10.1038/s44286-025-00222-w","DOIUrl":"10.1038/s44286-025-00222-w","url":null,"abstract":"Zizhao Wu and Peng Xu discuss key metrics in biomanufacturing, highlighting their role in optimizing microbial processes for scalable and cost-efficient production.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"334-334"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yixuan Zhao, Junhao Liao, Saiyu Bu, Zhaoning Hu, Jingyi Hu, Qi Lu, Mingpeng Shang, Bingbing Guo, Ge Chen, Qian Zhao, Kaicheng Jia, Guorui Wang, Ethan Errington, Qin Xie, Yanfeng Zhang, Miao Guo, Boyang Mao, Li Lin, Zhongfan Liu
{"title":"Automated processing and transfer of two-dimensional materials with robotics","authors":"Yixuan Zhao, Junhao Liao, Saiyu Bu, Zhaoning Hu, Jingyi Hu, Qi Lu, Mingpeng Shang, Bingbing Guo, Ge Chen, Qian Zhao, Kaicheng Jia, Guorui Wang, Ethan Errington, Qin Xie, Yanfeng Zhang, Miao Guo, Boyang Mao, Li Lin, Zhongfan Liu","doi":"10.1038/s44286-025-00227-5","DOIUrl":"10.1038/s44286-025-00227-5","url":null,"abstract":"Chemical vapor deposition (CVD) has enabled two-dimensional (2D) materials and their heterostructures to become promising material platforms for next-generation electronics and photonic devices. However, the robust processing of 2D materials produced by CVD is currently hindered by the lack of a scalable and reliable technique to transfer materials from their growth substrates to target substrates for end applications. Here we introduced an automated system to enable the transfer of CVD-grown 2D materials with robotics by engineering the interfacial adhesion and strain. The developed automated transfer system shows industrial compatibility, as demonstrated by the high production capability (up to 180 wafers per day), reliable transfer quality (with transferred graphene carrier mobilities over 14,000 cm2 V−1 s−1), and high uniformity and repeatability of the transferred materials. The developed system also outperforms conventional manual transfer methods in terms of minimizing cost and environmental impact. This automated system could accelerate the research and commercialization of 2D materials in the future. Robust, high-throughput processing of two-dimensional materials produced by chemical vapor deposition requires a reliable and scalable technique to transfer the materials to a target substrate. An automated system for transferring chemical-vapor-deposited two-dimensional materials using robotics is developed, demonstrating high production capability with uniformity and repeatability of the transferred materials.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"296-308"},"PeriodicalIF":0.0,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jingcheng Ma, Megan Laune, Pengju Li, Jing Lu, Jiping Yue, Yueyue Yu, Yamin Mansur, Amio P. D. Ritwik, Sai P. Peri, Jessica Cleary, Kaitlyn Oliphant, Zachary Kessler, Erika C. Claud, Bozhi Tian
{"title":"Airborne biomarker localization engine for open-air point-of-care detection","authors":"Jingcheng Ma, Megan Laune, Pengju Li, Jing Lu, Jiping Yue, Yueyue Yu, Yamin Mansur, Amio P. D. Ritwik, Sai P. Peri, Jessica Cleary, Kaitlyn Oliphant, Zachary Kessler, Erika C. Claud, Bozhi Tian","doi":"10.1038/s44286-025-00223-9","DOIUrl":"10.1038/s44286-025-00223-9","url":null,"abstract":"Unlike biomarkers in biofluids, airborne biomarkers are dilute and difficult to trace. Detecting diverse airborne biomarkers with sufficient sensitivity typically relies on bulky and expensive equipment like mass spectrometers that remain inaccessible to the general population. Here we introduce airborne biomarker localization engine (ABLE), a simple, affordable and portable platform that can detect both non-volatile and volatile molecules and particulate biomarkers from open air in about 15 min. ABLE substantially improves the gas detection limits by converting dilute gases into droplets by water condensation, producing concentrated aqueous samples that can be easily tested by existing liquid-sensing platforms. Fundamental studies of multiphase condensation revealed unexpected stability in condensate-trapped biomarkers, making ABLE a reliable, accessible and high-performance system for open-air-based biosensing applications such as non-contact infant healthcare, pathogen detection in public spaces and food safety monitoring. Detecting dilute airborne biomarkers is important in healthcare but is limited by the low sensitivity of current gas sensors. A portable, low-cost device is introduced that uses water condensation to enrich airborne biomarkers into a concentrated liquid, enabling existing liquid sensors to detect biomarkers with high sensitivity and broad accessibility.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"321-333"},"PeriodicalIF":0.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Delgado-Licona, Daniel Addington, Abdulrahman Alsaiari, Milad Abolhasani
{"title":"Engineering principles for self-driving laboratories","authors":"Fernando Delgado-Licona, Daniel Addington, Abdulrahman Alsaiari, Milad Abolhasani","doi":"10.1038/s44286-025-00217-7","DOIUrl":"10.1038/s44286-025-00217-7","url":null,"abstract":"The chemical engineering field stands at a pivotal moment of transformation, driven in part by the convergence of process automation, robotics and artificial intelligence into self-driving laboratories (SDLs) to accelerate scientific discoveries. This Comment explores how process intensification principles can guide the development of SDLs to accelerate innovation while ensuring efficient use of resources across the multiscale chemical domain.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"277-280"},"PeriodicalIF":0.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Calculating the cost of using renewable energy in power-to-X processes","authors":"","doi":"10.1038/s44286-025-00224-8","DOIUrl":"10.1038/s44286-025-00224-8","url":null,"abstract":"Electrification of the chemical industry with renewable energy is critical for achieving net-zero goals, but coping with the intermittency of renewables such as wind and solar power is challenging. An assessment of the true cost of utilizing intermittent renewable energy reveals the benefits and the economic drivers for energy curtailment.","PeriodicalId":501699,"journal":{"name":"Nature Chemical Engineering","volume":"2 5","pages":"294-295"},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145123119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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