Nutrition and Cancer最新文献_第3页

Is There a Relationship between County-Level Food Insecurity Rates and Breast Cancer Stage at Diagnosis? 县级食品不安全率与乳腺癌诊断阶段之间是否存在关系?

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-07-23 DOI: 10.1080/01635581.2021.1952624

Chinedum O Ojinnaka, Jaclyn Christ, Meg Bruening

{"title":"Is There a Relationship between County-Level Food Insecurity Rates and Breast Cancer Stage at Diagnosis?","authors":"Chinedum O Ojinnaka, Jaclyn Christ, Meg Bruening","doi":"10.1080/01635581.2021.1952624","DOIUrl":"https://doi.org/10.1080/01635581.2021.1952624","url":null,"abstract":"The relationship between county food insecurity (FI) rate and breast cancer stage at diagnosis is not clear. Using 2010-2016 Surveillance Epidemiology and End Results (SEER) and Feeding America data we analyzed the association between county FI rate in quartiles (low, medium, high, very high) and breast cancer stage at diagnosis among adult females (≥18 years). We also analyzed the effect of insurance status and county poverty level on this relationship, and whether this relationship varies among non-elderly (<65 years) and elderly (≥ 65 years) individuals. Bivariate and multivariable multilevel logistic regression were used for analyses. Bivariate analysis showed increased likelihood of late-stage breast cancer with increasing county FI rate. This relationship persisted after adjusting for insurance status but was no longer significant after adjusting for county-level poverty rate. There was a statistically significant association between counties with very high food insecurity rates and late-stage breast cancer diagnosis (OR = 1.07; 95% CI = 1.00, 1.14) among the elderly population. Very high county food insecurity rate was associated with late-stage breast cancer among elderly women. Population-level interventions focused on counties with very high food insecurity rates could reduce disparities in stage at breast cancer diagnosis among elderly women.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"1291-1298"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01635581.2021.1952624","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39216064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Preoperative Nutritional Status in Elderly Inpatients with Gastrointestinal Cancer and Its Linear Association with Frailty. 老年住院胃肠道肿瘤患者术前营养状况及其与虚弱的线性关系

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-07-26 DOI: 10.1080/01635581.2021.1955284

Qianqian Zhang, Shihui Yu, Qingfeng Li, Meng Zhang, Lei Meng, Shaohua Hu

{"title":"Preoperative Nutritional Status in Elderly Inpatients with Gastrointestinal Cancer and Its Linear Association with Frailty.","authors":"Qianqian Zhang, Shihui Yu, Qingfeng Li, Meng Zhang, Lei Meng, Shaohua Hu","doi":"10.1080/01635581.2021.1955284","DOIUrl":"https://doi.org/10.1080/01635581.2021.1955284","url":null,"abstract":"The identification and management of malnutrition is increasingly considered as an important issue in cancer treatment. This study aimed at determining the prevalence of malnutrition among elderly inpatients with gastrointestinal cancer. Meanwhile, the exact relationship between nutrition and frailty was explored. The presence of malnutrition was determined using Mini-Nutritional Assessment Short Form (MNA-SF), Nutrition Risk Screening 2002 (NRS2002), and a batch of laboratory parameters. A cross-sectional study of 265 eligible elderly inpatients with gastrointestinal cancer was conducted. The results showed that the prevalence of malnutrition classified by MNA-SF, NRS2002, albumin, prealbumin, total protein, hemoglobin, and total lymphocyte count were 66.8%, 68.7%, 41.5%, 27.9%, 39.2%, 40.8%, and 15.5%, respectively. There was a fair agreement between MNA-SF and NRS2002 (Kappa = 0.335, P < 0.001) in screening malnutrition. According to the albumin criterion, both MNA-SF and NRS2002 exhibited better sensitivity (72.7% and 76.4%, respectively) but poor specificity (37.4% and 36.8%, respectively) in screening malnutrition. A significant linear correlation between MNA-SF (NRS2002) and frailty was discovered (β=-0.259 and β = 0.412, respectively, P < 0.001). By identifying malnutrition in this elderly population, targeted plans can be developed as a part of cancer treatment and care. A better nutritional screening tool with both high sensitivity and specificity should be selected or developed.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"1376-1387"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01635581.2021.1955284","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39222439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Diet and Genetic Risk Factors of Colorectal Cancer in Palestine: A Case-Control Study. 巴勒斯坦结直肠癌的饮食和遗传危险因素:一项病例对照研究。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-12-08 DOI: 10.1080/01635581.2021.2013507

Issa Ghrouz, Nuha El Sharif

{"title":"Diet and Genetic Risk Factors of Colorectal Cancer in Palestine: A Case-Control Study.","authors":"Issa Ghrouz, Nuha El Sharif","doi":"10.1080/01635581.2021.2013507","DOIUrl":"https://doi.org/10.1080/01635581.2021.2013507","url":null,"abstract":"To add evidence to the limited data available on colorectal cancer (CRC) from Palestine, we examine the risk factors associated with CRC using a matched hospital-based case-control study. A structured questionnaire was used to collect data from 105 cases and 105 controls. A multivariable conditional regression model was used to adjust for the association between study factors and CRC risk. In the model, compared with controls, cases from villages were significantly less likely to have CRC (Adjusted Odds Ratio, AOR = 0.194); taking aspirin lowered the likelihood of CRC by 24%; and having a multiple birth sibling by 33%. Also, the likelihood of CRC was lowered significantly by consuming five servings of fruits/vegetables per week or more (5-6 servings: AOR = 0.21, 7-8 servings per week: AOR = 0.04). However, cases had a significantly higher likelihood of CRC if they consumed 2-4 servings of grilled red meat per week (AOR = 4.25); smoked (AOR = 4.38); had a sedentary lifestyle (AOR = 2.53); reported parental consanguinity (AOR = 3.88); or had a family history of cancer (AOR = 6.39). Our results confirmed the association between CRC and red meat intake and smoking, and proved that parental consanguinity and family history of cancer are also risk factors for CRC.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2460-2469"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39700743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Ethanol Extract of Eryngium Foetidum Leaves Induces Mitochondrial Associated Apoptosis via ROS Generation in Human Gastric Cancer Cells. 茯苓叶乙醇提取物通过ROS诱导人胃癌细胞线粒体相关凋亡

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2022-01-24 DOI: 10.1080/01635581.2022.2028864

Xian Zhang, Jing Chen, Songlin Zhou, Huange Zhao

{"title":"Ethanol Extract of Eryngium Foetidum Leaves Induces Mitochondrial Associated Apoptosis via ROS Generation in Human Gastric Cancer Cells.","authors":"Xian Zhang, Jing Chen, Songlin Zhou, Huange Zhao","doi":"10.1080/01635581.2022.2028864","DOIUrl":"https://doi.org/10.1080/01635581.2022.2028864","url":null,"abstract":"Background: Eryngium foetidum has long been used as a food ingredient and folk medicine in tropical regions. The anticancer activity of EF extract and the mechanisms remains unclear. Herein, we prepared four solvent extracts of EF leaves, detected the cytotoxic effects, and explored the potential mechanism by which these extracts induce cell death. Methods: The anticancer activity of the EF extracts was measured by MTT, CCK-8 and BrdU assays. The cell cycle was evaluated by flow cytometry and western blot. Apoptotic events were investigated with Hoechst, Annexin V/PI assays and western blot. The mitochondrial membrane potential was monitored using JC-1 staining, and ROS production was assessed with immunofluorescence. Results: The ethanol extract of EF leaves exhibited the strongest cytotoxic effect against SGC-7901 cells. The EFE extract significantly inhibited the SGC-7901 cells viability, arrested the cell cycle, increased the numbers of apoptotic cells, caused the loss of MMP, increased the Bax/Bcl-2 ratio, and led to cytochrome c release, and triggered ROS production. Conclusion: Our findings demonstrated for the first time that EFE extract induces mitochondrial associated apoptosis via ROS generation in SGC-7901 cells. Thus, EFE extract could be identified as a potential edible phytotherapy for the treatment of human gastric cancer.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2996-3006"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39712517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Anticancer Activity and Molecular Mechanism of Momordica cochinchinensis Seed Extract in Chronic Myeloid Leukemia Cells. 苦瓜种子提取物对慢性髓系白血病细胞的抗癌活性及分子机制研究。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-12-15 DOI: 10.1080/01635581.2021.2014904

Zhengdong Ai, Chong Ma, Ruiming Wan, Jingyi Yin, Guiming Li, Yan Li, Li Chen

{"title":"Anticancer Activity and Molecular Mechanism of Momordica cochinchinensis Seed Extract in Chronic Myeloid Leukemia Cells.","authors":"Zhengdong Ai, Chong Ma, Ruiming Wan, Jingyi Yin, Guiming Li, Yan Li, Li Chen","doi":"10.1080/01635581.2021.2014904","DOIUrl":"https://doi.org/10.1080/01635581.2021.2014904","url":null,"abstract":"Targeting Bcr-Abl is the key to the treatment of chronic myeloid leukemia. Despite great progress in the treatment of patients with chronic CML, advanced CML patients are still unable to obtain effective and safe drugs. Momordica cochinchinensis seed is the dried ripe seed of Momordica cochinchinensis, which is a kind of fruit and consumed for dietary as well as medicinal uses. This study aimed to investigate the anticancer activity of Momordica cochinchinensis seed extract (MCSE) in CML cells. CML cells (KBM5 and KBM5-T315I) were treated with MCSE and analyzed for growth, apoptosis, and signal transduction. Nude mouse xenograft model was used to evaluate the antitumor activity of MCSE In Vivo. MCSE significantly reduced the cell viability of CML cells, triggered G0/G1 phase arrest in KBM5 cells and S phase arrest in KBM5-T315I cells. Concurrently, MCSE caused the activation of caspase-3, -8, -9, PARP and the degradation of Mcl-1, ultimately triggering endogenous and exogenous cell apoptosis. Meanwhile, MCSE downregulated Bcr-Abl levels and its downstream signaling pathways. Additionally, MCSE inhibited the growth of CML cells in nude mouse xenografts. Taken together, this study demonstrated the anticancer mechanism of MCSE, namely blocking Bcr-Abl and downregulating Mcl-1, and finally induced apoptosis of CML cells.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2644-2656"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39725804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-12-20 DOI: 10.1080/01635581.2021.2014902

Vanessa Fuchs-Tarlovsky, Juan Carlos Castillo Pineda, Dolores Rodríguez Veintimilla, Isabel Calvo Higuera, Peter Grijalva Guerrero, Anel Gómez García, Evelyn Frias-Toral, Sergio Santana Porbén

{"title":"Cancer-Related Malnutrition: Epidemiological Results from the Latin American Study of Malnutrition in the Oncology Practice.","authors":"Vanessa Fuchs-Tarlovsky, Juan Carlos Castillo Pineda, Dolores Rodríguez Veintimilla, Isabel Calvo Higuera, Peter Grijalva Guerrero, Anel Gómez García, Evelyn Frias-Toral, Sergio Santana Porbén","doi":"10.1080/01635581.2021.2014902","DOIUrl":"https://doi.org/10.1080/01635581.2021.2014902","url":null,"abstract":"Abstract Background: Malnutrition can affect the patient diagnosed with, and treated for, cancer. However, until a dedicated study is completed, estimates of malnutrition rates will be disparate and unrepresentative of cancer patients’ nutritional reality. Objective: To estimate the prevalence of malnutrition among patients being cared for cancer in Latin American (LATAM) hospitals by means of a multicenter, multinational study. Methods: The Latin American Study of Malnutrition in Oncology (LASOMO) was completed with 1,842 patients (Women: 56.2%; Age ≥ 60 years: 43.2%; Chemotherapy: 55.1%; Radiotherapy: 17.8%; Surgery: 27.1%) assisted at 52 health centers from 10 LATAM countries. Malnutrition prevalence was estimated from the (B + C) scores assigned to the patient with the Subjective Global Assessment by Detsky et al. (1987). Malnutrition prevalence was distributed regarding the demographic features of the patient, the primary tumor location, and the current cytoreducing treatment. Results: Malnutrition affected 59.1% of the surveyed patients. Malnutrition prevalence was higher among male patients and those with tumors of the digestive tract and the hemolymphopoietic system. Malnutrition was also associated with the current cytoreducing modality, with chemotherapy returning the highest prevalence. Conclusions: Malnutrition can be present in more than half of the patients being cared for cancer in LATAM health centers. Supplemental data for this article is available online at https://doi.org/10.1080/01635581.2021.2014902","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2479-2488"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39742118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Occurrence of Dysgeusia in Patients Being Treated for Cancer. 癌症治疗中出现的发音障碍。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2022-02-23 DOI: 10.1080/01635581.2022.2042569

Jaclyn Di Meglio, Monica Dinu, Laura Doni, Gemma Rossi, Roberta Giorgione, Barbara Colombini, Lorenzo Antonuzzo, Francesco Sofi

{"title":"Occurrence of Dysgeusia in Patients Being Treated for Cancer.","authors":"Jaclyn Di Meglio, Monica Dinu, Laura Doni, Gemma Rossi, Roberta Giorgione, Barbara Colombini, Lorenzo Antonuzzo, Francesco Sofi","doi":"10.1080/01635581.2022.2042569","DOIUrl":"https://doi.org/10.1080/01635581.2022.2042569","url":null,"abstract":"The aims of this study were to assess the presence of dysgeusia in patients receiving anticancer therapy and to explore possible factors influencing its occurrence. A total of 242 adult patients with histological diagnoses of malignant neoplasia and undergoing all types of anticancer treatment were included in the analysis. Data were collected from May 2019 to November 2019 at the Unit of Medical Oncology of Careggi University Hospital, Florence, Italy. Dysgeusia was assessed using the Chemotherapy-induced Taste Alteration Scale (CiTAS), while treatment-related symptoms were assessed using the Common Terminology Criteria for Adverse Events (CTCAE). Patients were aged 68 ± 13 years, mostly males (65%). A large proportion of them was undergoing chemotherapy (42.2%), while the others were receiving immunotherapy (20.7%), hormone therapy (15.5%), targeted therapy (12.8%), or a combination of them. Overall, 21.5% of patients reported dysgeusia, 17.4% nausea, 10.7% dysosmia, 9.9% xerostomia, 4.5% mucositis, and only 3.7% vomiting. The targeted therapy showed the greatest adverse effects, followed by chemotherapy, immunotherapy, and hormone therapy. When patients with dysgeusia were analyzed, phantogeusia and parageusia was the most affected dimension of gustatory disorders. Significant differences (p < 0.05) in CiTAS scores were found according to treatment-related symptoms for nausea and mucositis.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2868-2874"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39822490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of Fermented Wheat Germ Extract on Oral Cancer Cells: An In Vitro Study. 发酵小麦胚芽提取物对口腔癌细胞的体外作用研究

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-09-12 DOI: 10.1080/01635581.2021.1976806

Khrystyna Zhurakivska, Maija Risteli, Tuula Salo, Davide Sartini, Alessia Salvucci, Giuseppe Troiano, Lorenzo Lo Muzio, Monica Emanuelli

{"title":"Effects of Fermented Wheat Germ Extract on Oral Cancer Cells: An In Vitro Study.","authors":"Khrystyna Zhurakivska, Maija Risteli, Tuula Salo, Davide Sartini, Alessia Salvucci, Giuseppe Troiano, Lorenzo Lo Muzio, Monica Emanuelli","doi":"10.1080/01635581.2021.1976806","DOIUrl":"https://doi.org/10.1080/01635581.2021.1976806","url":null,"abstract":"Oral carcinoma is one of the most aggressive cancers, and despite the advances in the therapy, its mortality is still high. An attention in cancer treatment has focused on natural compounds due to their potential beneficial effects on human health. In this study, the effects of dietary supplement Fermented Wheat Germ Extract (FWGE) on oral tongue squamous cell carcinoma (OTSCC) cells were investigated In Vitro using three cell lines (HSC-3, SAS, SCC-25) with variable aggressiveness. The cell viability was significantly decreased by the treatment with high concentration of FWGE in every cell line. Regarding migration and invasion, HSC-3 and SCC-25 cells were most sensitive to FWGE since their movement was significantly reduced with 5 and 10 mg/ml FWGE, while SAS was inhibited only with 10 mg/ml FWGE. Chemotherapeutic compounds (cisplatin and 5-fluorouracil) significantly reduced all OTSCC cells viability. Importantly, combination of these drugs with 10 mg/ml FWGE significantly decreased the cell viability compared to the treatment with the chemotherapeutics or FWGE alone. Based on these In Vitro experiments, the use of FWGE seems to improve the anticancer effects on OTSCC cells. Further In Vivo and clinical studies should be conducted to verify the positive effects of FWGE for OTSCC patients.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2133-2141"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39411074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are Serum Ferritin Levels a Reliable Cancer Biomarker? A Systematic Review and Meta-Analysis. 血清铁蛋白水平是可靠的癌症生物标志物吗?系统回顾和荟萃分析。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-10-05 DOI: 10.1080/01635581.2021.1982996

Wilmer Ramírez-Carmona, Beatriz Díaz-Fabregat, Andreia Yuri Yoshigae, Ariana Musa de Aquino, Wellerson Rodrigo Scarano, Anthony César de Souza Castilho, Juliane Avansini Marsicano, Rosana Leal do Prado, Juliano Pelim Pessan, Leonardo de Oliveira Mendes

{"title":"Are Serum Ferritin Levels a Reliable Cancer Biomarker? A Systematic Review and Meta-Analysis.","authors":"Wilmer Ramírez-Carmona, Beatriz Díaz-Fabregat, Andreia Yuri Yoshigae, Ariana Musa de Aquino, Wellerson Rodrigo Scarano, Anthony César de Souza Castilho, Juliane Avansini Marsicano, Rosana Leal do Prado, Juliano Pelim Pessan, Leonardo de Oliveira Mendes","doi":"10.1080/01635581.2021.1982996","DOIUrl":"https://doi.org/10.1080/01635581.2021.1982996","url":null,"abstract":"Although serum ferritin (SF) has been shown in several studies to be a potential cancer biomarker, the results are inconsistent. Herein, a systematic review was performed to investigate the clinical SF levels in different types of tumors in order to verify the role of SF levels as a biomarker for cancer diagnosis. The search was performed using the PubMed/Medline, Cochrane Library, and Scopus databases. Observational studies comparing SF levels between healthy adults and patients with cancer were included. The meta-analysis was carried out according to the inverse variance and random effects model. The standardized mean differences (SMDs) were assessed at 95% confidence intervals (CIs). We found that SF was higher in patients with cancer (SMD 3.07; CI 1.96,4.17), especially for head and neck cancer (SMD 3.88; CI 0.42,7.34), lung cancer (SMD 1.72; CI 0.67,2.78), pancreatic cancer (SMD 6.79; CI 5.66,7.91), and renal cell carcinoma (SMD 1.77; CI 0.48,3.05). Moreover, in the advanced stages (Stages III and IV), ferritin levels were higher than in healthy adults (SMD 4.89; CI 2.72,7.06, and SMD 8.40; CI 6.99,9.82, respectively). SF acts as a biomarker for pancreatic cancer, renal cell carcinoma, lung cancer, and head and neck cancer and is a sensitive biomarker for the detection of advanced stages of tumors.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"1917-1926"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39486517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Diet Changes and Underlying Motives in Cancer Patients. 癌症患者的饮食改变及其潜在动机

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-10-05 DOI: 10.1080/01635581.2021.1986553

Alexandra Schmid, Viktoria Mathies, Jens Buentzel, Christian Keinki, Jutta Huebner

{"title":"Diet Changes and Underlying Motives in Cancer Patients.","authors":"Alexandra Schmid, Viktoria Mathies, Jens Buentzel, Christian Keinki, Jutta Huebner","doi":"10.1080/01635581.2021.1986553","DOIUrl":"https://doi.org/10.1080/01635581.2021.1986553","url":null,"abstract":"With rising cancer incidence rates and numbers of long-term cancer survivors, diet increasingly comes into view of patients as well as healthcare providers. The aim was to analyze cancer patients' concepts of nutrition, changes in diet and reasons for these changes. This study is a cross-sectional single-center study. Data was collected 12/2017 - 01/2019 using a questionnaire. The study was set at an outpatient department at a German university hospital. 102 patients (male n = 47, female n = 54; age 34 to 86 years [mean = 62.3]) with cancer were included in the study. Statistical calculation was performed with Mann-Whitney-U-Test and Wilcoxon-signed-rank. p < 0.05 was considered significant. Patients were more concerned with diet after their diagnosis than before (p < 0.01). Seventy-one (70%) patients reported that they changed their diet or planned to do so. Some changes included an increased intake of vegetables or fruits. Patients who changed their diet more often were convinced that there was a positive influence of diet on the course of cancer (p < 0.05). Diet is an important topic for many cancer patients. Some patients seem to have a lack of information regarding the effect of diet on health. Physicians and dietitians should provide more education on healthy and safe diets for cancer patients.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"2017-2028"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39508946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1