Nutrition and Cancer最新文献

Unveiling the Impact of Epstein-Barr Virus on the Risk of Prostate Cancer: A Mendelian Randomization Study. 揭示 Epstein-Barr 病毒对前列腺癌风险的影响：孟德尔随机研究》。

Nutrition and Cancer Pub Date : 2024-09-09 DOI: 10.1080/01635581.2024.2399868

Haihong Liao,Zhihan Wang,Yuhang Qian,Haojie Chen,Yuntian Shi,Jiacheng Huang,Xiuchen Guo,Mingming Yu,Yongjiang Yu

引用次数: 0

Exploring the Relationship Between Diet, Lifestyle and Gut Microbiome in Colorectal Cancer Development: A Recent Update 探索饮食、生活方式和肠道微生物组在结直肠癌发展中的关系：最新进展

Nutrition and Cancer Pub Date : 2024-06-18 DOI: 10.1080/01635581.2024.2367266

Biki Saha, Rithi A T, Subhamay Adhikary, Antara Banerjee, Arun Kumar Radhakrishnan, Asim K. Duttaroy, Surajit Pathak

引用次数: 0

Nutrition Risk Screening 2002 for Adult Cancer Patients: A Systematic Review and Meta-Analysis. 2002 年成人癌症患者营养风险筛查：系统回顾与元分析》。

Nutrition and Cancer Pub Date : 2024-05-17 DOI: 10.1080/01635581.2024.2352901

Pengpeng Wang, Yanmei Tan, Kim Lam Soh, Kim Geok Soh, C. Ning, Li Xue, Yunhong Lu, Jie Yang

{"title":"Nutrition Risk Screening 2002 for Adult Cancer Patients: A Systematic Review and Meta-Analysis.","authors":"Pengpeng Wang, Yanmei Tan, Kim Lam Soh, Kim Geok Soh, C. Ning, Li Xue, Yunhong Lu, Jie Yang","doi":"10.1080/01635581.2024.2352901","DOIUrl":"https://doi.org/10.1080/01635581.2024.2352901","url":null,"abstract":"It is critical to screen and assess malnutrition in cancer patients early. However, there is no uniform standard for nutritional risk screening and malnutrition assessment. We aimed to analyze the effects of the Nutrition Risk Screening 2002 (NRS2002) in screening for nutritional risk among adult cancer patients, using the Patient-Generated Subjective Global Assessment (PG-SGA) as the reference standard. A systematic search was performed using PubMed, Embase, Web of Science, the Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, and China Science and Technology Journal Database (VIP). Studies comparing NRS2002 with PG-SGA in adult cancer patients were included. To assess the quality of the included studies, the Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) was used. The combined sensitivity, specificity, diagnostic odds ratio (DOR), and the area under the receiver-operating characteristic curve (AUC) were calculated. In addition, sensitivity, subgroup, and publication bias analyses were performed. Thirteen articles involving 3,373 participants were included. The combined sensitivity, specificity, DOR, and AUC were 0.62 (95% CI, 0.60-0.64), 0.86 (95% CI, 0.84-0.88), 11.23 (95% CI, 8.26-15.27), and 0.85 (95% CI, 0.82-0.88), respectively. For adult cancer patients, NRS2002 has moderate sensitivity, high specificity, and high AUC in screening for nutritional risk.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":"6 10","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140963859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Body Composition Analysis Techniques and Its Application in Oncology: A Review. 身体成分分析技术及其在肿瘤学中的应用：综述。

Nutrition and Cancer Pub Date : 2024-05-17 DOI: 10.1080/01635581.2024.2353942

Anil Kumar Maurya, L. Aggarwal, Sunil Choudhary

{"title":"Body Composition Analysis Techniques and Its Application in Oncology: A Review.","authors":"Anil Kumar Maurya, L. Aggarwal, Sunil Choudhary","doi":"10.1080/01635581.2024.2353942","DOIUrl":"https://doi.org/10.1080/01635581.2024.2353942","url":null,"abstract":"The oncology community has shown growing interest to understand how body composition measures can be utilized to improve cancer treatment and survivorship care for about 20 million individuals diagnosed with cancer annually. Recent observational studies demonstrate that muscle and adipose tissue distribution are risk factors for clinical outcomes such as postoperative complications, and worse overall survival. There is an emergent recognition that body mass index (BMI) is neither adequate to identify patients with adverse health outcomes due to poor muscle health or excess adiposity, nor does BMI accurately classify the distribution of adiposity. Abdominal CT is a most frequently imaging examination for a wide variety of clinical indications, but it is only used to diagnose the immediate problem. Additionally, each CT examination contains very robust data on body composition which generally goes unused in routine clinical practice. The field is eager to identify therapeutic interventions that modify body composition and reduce the incidence of poor clinical outcomes in this population. Large scale population based screening is feasible now by making all of these relevant biometric measures fully automated through the use of artificial intelligence algorithms, which provide rapid and objective assessment.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":"5 6","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140962547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prophylactic Versus Reactive Megestrol Acetate Use for Critical Body Weight Loss in Patients with Pharyngeal and Laryngeal Squamous Cell Carcinoma Undergoing Concurrent Chemoradiotherapy. 咽和喉鳞状细胞癌患者同时接受化放疗时，预防性使用醋酸甲地孕酮与反应性使用醋酸甲地孕酮治疗临界体重减轻。

Nutrition and Cancer Pub Date : 2024-05-17 DOI: 10.1080/01635581.2024.2352185

C. Lin, Pei-Wei Huang, Chia-Hsun Hsieh, Cheng-Lung Hsu, C. Liau, Shiang-Fu Huang, Chun-Ta Liao, T. Chang, Hung-Ming Wang

{"title":"Prophylactic Versus Reactive Megestrol Acetate Use for Critical Body Weight Loss in Patients with Pharyngeal and Laryngeal Squamous Cell Carcinoma Undergoing Concurrent Chemoradiotherapy.","authors":"C. Lin, Pei-Wei Huang, Chia-Hsun Hsieh, Cheng-Lung Hsu, C. Liau, Shiang-Fu Huang, Chun-Ta Liao, T. Chang, Hung-Ming Wang","doi":"10.1080/01635581.2024.2352185","DOIUrl":"https://doi.org/10.1080/01635581.2024.2352185","url":null,"abstract":"This study compared the effects of megestrol acetate (MA) prophylactic (p-MA) versus reactive (r-MA) use for critical body-weight loss (>5% from baseline) during concurrent chemoradiotherapy (CCRT) in patients with advanced pharyngolaryngeal squamous cell carcinoma (PLSCC).\u0000Patients receiving CCRT alone in two phase-II trials were included for analyses. Both the p-MA and r-MA cohorts received the same treatment protocol at the same institution, and the critical body-weight loss, survival, and adverse event profiles were compared.\u0000The mean (SD) weight loss was 5.1% (4.7%) in the p-MA cohort (n = 54) vs. 8.1% (4.6%) in the r-MA cohort (n = 50) (p = .001). The percentage of subjects with body-weight loss >5% was 42.6% in the p-MA cohort vs. 68.0% in the r-MA cohort (p = .011). Tube feeding was needed in 22.2% of p-MA vs. 62.0% of r-MA patients (p < .001). Less neutropenia (26.0% vs. 70.0% [p < .001]) and a shorter duration of grade 3-4 mucositis (2.4 ± 1.4 vs. 3.6 ± 2.0 wk [p = .009]) were observed with p-MA treatment. Disease-specific survival, locoregional control, or distant metastasis-free survival did not differ. Less competing mortality from secondary primary cancer resulted in a better overall survival trend in the p-MA cohort.\u0000p-MA may reduce body-weight loss and improve adverse event profiles during CCRT for patients with PLSCC.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":"34 49","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2024-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140966452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipid Identification of Biomarkers in Esophageal Squamous Cell Carcinoma by Lipidomic Analysis. 通过脂质体分析鉴定食管鳞状细胞癌的生物标志物

Nutrition and Cancer Pub Date : 2024-05-16 DOI: 10.1080/01635581.2024.2350097

Tingwei Si, Daoqin Liu, Lei Li, Zichen Xu, Luqing Jiang, Ying Zhai, Qiwen Wu

{"title":"Lipid Identification of Biomarkers in Esophageal Squamous Cell Carcinoma by Lipidomic Analysis.","authors":"Tingwei Si, Daoqin Liu, Lei Li, Zichen Xu, Luqing Jiang, Ying Zhai, Qiwen Wu","doi":"10.1080/01635581.2024.2350097","DOIUrl":"https://doi.org/10.1080/01635581.2024.2350097","url":null,"abstract":"Lipids participate in many important biological functions through energy storage, membrane structure stabilization, signal transduction, and molecular recognition. Previous studies have shown that patients with esophageal squamous cell carcinoma (ESCC) have abnormal lipid metabolism. However, studies characterizing lipid metabolism in ESCC patients through lipidomics are limited. Plasma lipid profiles of 65 ESCC patients and 42 healthy controls (HC) were characterized by lipidomics-based ultraperformance liquid chromatography quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF-MS). Single-factor and multi-factor statistical analysis were used to screen the differences in blood lipids between groups, and combined with component ratio analysis and receiver operating characteristic (ROC) curve diagnostic efficiency assessment, to reveal the potential mechanisms and biomarkers of ESCC. There were significant differences in lipid profiles between the ESCC and HC groups. Thirty-six differential lipids (11 up-regulated and 25 down-regulated) were selected based on the criteria of p < .05 and fold change > 1.3 or < 0.77. Glycerophospholipids were the major differential lipids, suggesting that these lipid metabolic pathways exhibit a significant imbalance that may contribute to the development of esophageal squamous cell carcinoma. Among them, the seven candidate biomarkers for esophageal squamous cell carcinoma with the highest diagnostic value are three phosphatidylserine (PS), three fatty acids (FA) and one phosphatidylcholine (PC).","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":"3 1","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140969243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Pilot Study to Determine the Effect of Individualized Enteral Nutrition Management Based on Prognostic Nutrition Index on Surgical Patients With Oral Malignancies 根据口腔恶性肿瘤手术患者预后营养指数确定个性化肠内营养管理效果的试点研究

Nutrition and Cancer Pub Date : 2024-04-29 DOI: 10.1080/01635581.2024.2344251

Chunbo Ding, Long Chen, Hedan Gu, Bin Xu, Yaqin Du

引用次数: 0

Pre-Operative Immunonutrition Enhances Postoperative Outcomes and Elevates Tumor-Infiltrating Lymphocyte Counts in Colorectal Cancer Patients: A Meta-Analysis of Randomized Controlled Trials. 术前免疫营养可增强结直肠癌患者的术后效果并提高肿瘤浸润淋巴细胞计数：随机对照试验的 Meta 分析。

Nutrition and Cancer Pub Date : 2024-04-24 DOI: 10.1080/01635581.2024.2344250

Mingqi Zhang, Guo-Feng Chen, Xiaoli Jin, Jun Wang, Shaojun Yu

{"title":"Pre-Operative Immunonutrition Enhances Postoperative Outcomes and Elevates Tumor-Infiltrating Lymphocyte Counts in Colorectal Cancer Patients: A Meta-Analysis of Randomized Controlled Trials.","authors":"Mingqi Zhang, Guo-Feng Chen, Xiaoli Jin, Jun Wang, Shaojun Yu","doi":"10.1080/01635581.2024.2344250","DOIUrl":"https://doi.org/10.1080/01635581.2024.2344250","url":null,"abstract":"OBJECTIVE\u0000This study (CRD42023464989) aimed to explore the effects of pre-operation immunonutrition on safety and immune related factors in colorectal cancer patients undergoing surgery.\u0000\u0000\u0000METHODS\u0000We systematically searched PubMed, Embase, and Wanfang databases to collect all clinical randomized controlled trials of the application of pre-operation immunonutrition for patients with colorectal cancer, published until July 2023. The primary outcomes were safety and immune related factors.\u0000\u0000\u0000RESULTS\u0000A total of 16 studies were finally included. Preoperative immunonutrition could reduce the postoperative infection rate (risk ratio (RR) = 0.56, 95% confidence interval (CI): 0.36, 0.88; p = .01), and wound infection rate (RR = 0.44, 95% CI: 0.27, 0.70; p < .001) in patients with colorectal cancer. For length of stay (mean difference (MD) = -1.10, 95% CI: -2.70, 0.49; p = .17), it was similar between groups. Meanwhile, patients in the pre-operation immune nutrition group also had significantly increased infiltrative lymphocytes CD16+ (MD = 0.04, 95% CI: 0.02, 0.06; p < .001), and CD56+ (MD = 0.05, 95% CI: 0.03, 0.06; p < .001) cells in the tumor tissues, compared to the control group.\u0000\u0000\u0000CONCLUSION\u0000Immunonutrition intervention has the potential to reduce postoperative infectious complications and improve tumor infiltrative lymphocytes in patients with colorectal cancer undergoing surgery.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":"31 6","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140662444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intestinal Bacteria Fluctuating in Early-Stage Colorectal Cancer Carcinogenesis are Associated with Diet in Healthy Adults 早期结直肠癌癌变过程中的肠道细菌波动与健康成年人的饮食有关

Nutrition and Cancer Pub Date : 2024-04-20 DOI: 10.1080/01635581.2024.2344257

Nobuhiro Narii, Ling Zha, Tomotaka Sobue, Tetsuhisa Kitamura, Masayo Komatsu, Yoshimitsu Shimomura, Satoshi Shiba, Sayaka Mizutani, Takuji Yamada, Shinichi Yachida

引用次数: 0

Perioperative and Postoperative Continuous Nutritional Counseling Improves Quality of Life of Gastric Cancer Patient Undergoing Gastrectomy 围手术期和术后持续营养咨询可提高接受胃切除术的胃癌患者的生活质量

Nutrition and Cancer Pub Date : 2024-04-15 DOI: 10.1080/01635581.2024.2340782

Shunya Hanzawa, Satoru Kikuchi, Shinji Kuroda, Ryohei Shoji, Hajime Kashima, Yuki Matsumi, Ayako Takahashi, Yoshihiko Kakiuchi, Kosei Takagi, Shunsuke Tanabe, Kazuhiro Noma, Shunsuke Kagawa, Kenichi Shikata, Toshiyoshi Fujiwara

引用次数: 0