Nutrition and Cancer最新文献_第2页

Impact of Immunonutrition on Nutritional Status in Patients Undergoing Colorectal Cancer Surgery: A Randomized Controlled Clinical Trial 免疫营养对结直肠癌手术患者营养状况的影响：随机对照临床试验

Nutrition and Cancer Pub Date : 2024-04-13 DOI: 10.1080/01635581.2024.2338607

Bedriye Ural, Elvan Yılmaz-Akyüz, Cebrail Akyüz

引用次数: 0

A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy 蛋氨酸限制饮食与同期放疗的 I 期试验

Nutrition and Cancer Pub Date : 2024-04-09 DOI: 10.1080/01635581.2024.2340784

Malcolm D. Mattes, Igor Koturbash, Calvin N. Leung, Sijin Wen, Geraldine M. Jacobson

引用次数: 0

Indole-3-Carbinol Promotes Apoptosis and Inhibits the Metastasis of Esophageal Squamous Cell Carcinoma by Downregulating the Wnt/β-Catenin Signaling Pathway 吲哚-3-卡比醇通过下调 Wnt/β-Catenin 信号通路促进食管鳞状细胞癌的凋亡并抑制其转移

Nutrition and Cancer Pub Date : 2024-04-08 DOI: 10.1080/01635581.2024.2337159

Qiao Chen, Congbo Jiang, Hui Li

引用次数: 0

Astaxanthin Ameliorates Skeletal Muscle Atrophy in Mice With Cancer Cachexia 虾青素可改善癌症小鼠的骨骼肌萎缩

Nutrition and Cancer Pub Date : 2024-04-03 DOI: 10.1080/01635581.2024.2335584

Xinyue Yu, Pengfei Ren, Ruzhen Yang, Han Yue, Qingjuan Tang, Changhu Xue

引用次数: 0

Effects of L-Carnitine and Coenzyme Q10 Supplementation on Lower Urinary Tract Symptoms in Men with Benign Prostatic Hyperplasia: A Randomized, Controlled, Clinical Trial 补充左旋肉碱和辅酶 Q10 对良性前列腺增生症男性下尿路症状的影响：随机对照临床试验

Nutrition and Cancer Pub Date : 2023-12-17 DOI: 10.1080/01635581.2023.2295578

Mahsa Norouzi, Sepideh Mahboobi, Mohammad Hassan Eftekhari, Mehdi Salehipour, Haleh Ghaem, Ali Mirzakhanlouei, Mohammad Ali Mohsenpour

引用次数: 0

Effect of Nutritional Intervention on the Management of Radiotherapy and Chemotherapy for Nasopharyngeal Carcinoma 营养干预对鼻咽癌放疗和化疗管理的影响

Nutrition and Cancer Pub Date : 2023-12-11 DOI: 10.1080/01635581.2023.2281036

Fengrong Tang, Peng Wang, Yixian Ye

引用次数: 0

Sarcopenia Index Predicts Short-Term Prognosis of Head and Neck Squamous Cell Carcinoma 肌肉疏松指数可预测头颈部鳞状细胞癌的短期预后

Nutrition and Cancer Pub Date : 2023-12-08 DOI: 10.1080/01635581.2023.2290299

Ryusuke Shodo, Keisuke Yamazaki, Yushi Ueki, Takeshi Takahashi, Yusuke Yokoyama, Arata Horii

引用次数: 0

Body Mass Index Alters the Predictive Value of the Neutrophil-to-Lymphocyte Ratio and Systemic Inflammation Response Index in Laryngeal Squamous Cell Carcinoma Patients. 体重指数改变中性粒细胞与淋巴细胞比值和喉癌患者全身炎症反应指数的预测价值。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-07-19 DOI: 10.1080/01635581.2021.1952447

Luana Dalbem Murad, Thays de Queiroz Silva, Arthur Orlando Corrêa Schilithz, Mariana Costa Monteiro, Leonardo Borges Murad, Eliane Fialho

{"title":"Body Mass Index Alters the Predictive Value of the Neutrophil-to-Lymphocyte Ratio and Systemic Inflammation Response Index in Laryngeal Squamous Cell Carcinoma Patients.","authors":"Luana Dalbem Murad, Thays de Queiroz Silva, Arthur Orlando Corrêa Schilithz, Mariana Costa Monteiro, Leonardo Borges Murad, Eliane Fialho","doi":"10.1080/01635581.2021.1952447","DOIUrl":"https://doi.org/10.1080/01635581.2021.1952447","url":null,"abstract":"Laryngeal squamous cell carcinoma (LSCC) is a frequent cancer subtype among head and neck cancers. Exacerbated inflammation and nutritional deficit are common features in this type of cancer and can be used as a prognostic marker. This study aimed to investigate the relationship between body mass index (BMI), neutrophil-to-lymphocyte ratio (NLR), and systemic inflammation response index (SIRI) on overall survival (OS) of LSCC patients. In this retrospective cohort study, 168 patients were followed for 5 years. Data on clinical factors, patients' life habits, height, weight, and hematological parameters were collected. BMI, NLR, and SIRI were calculated. Pretreatment NLR≥ 2.02 and SIRI≥ 1160.85 were independent prognostic factors for poor OS. Low BMI did not significantly affect the OS. However, the inflammatory parameters had their predictive capacity altered when stratified by the BMI classification. NLR≥ 2.02 + Low BMI or SIRI≥ 1160.85 + Low BMI increased in 8.6 and 3.8 times the risk of death, respectively. In contrast, stratification by normal/high BMI classification eliminated the predictive capacity of NLR and SIRI. Here, we demonstrated the possible ability of BMI to change the prognostic capacity of inflammatory markers NLR and SIRI in patients with LSCC.Supplemental data for this article is available online at https://doi.org/10.1080/01635581.2021.1952447.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"1261-1269"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01635581.2021.1952447","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39198189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Inhibition of Stearoyl-CoA Desaturase by Sterculic Oil Reduces Proliferation and Induces Apoptosis in Prostate Cancer Cell Lines. 甾醇油抑制硬脂酰辅酶a去饱和酶可抑制前列腺癌细胞增殖并诱导凋亡。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-07-20 DOI: 10.1080/01635581.2021.1952442

Eric Francisco Contreras-López, Carlos David Cruz-Hernández, Sergio Alberto Cortés-Ramírez, Abril Ramírez-Higuera, Carolina Peña-Montes, Mauricio Rodríguez-Dorantes, Rosa María Oliart-Ros

{"title":"Inhibition of Stearoyl-CoA Desaturase by Sterculic Oil Reduces Proliferation and Induces Apoptosis in Prostate Cancer Cell Lines.","authors":"Eric Francisco Contreras-López, Carlos David Cruz-Hernández, Sergio Alberto Cortés-Ramírez, Abril Ramírez-Higuera, Carolina Peña-Montes, Mauricio Rodríguez-Dorantes, Rosa María Oliart-Ros","doi":"10.1080/01635581.2021.1952442","DOIUrl":"https://doi.org/10.1080/01635581.2021.1952442","url":null,"abstract":"Prostate cancer (PCa) is a common type of cancer affecting male population. PCa treatments have side effects and are temporarily effective, so new therapeutic options are being investigated. Due to the high demand of energy for cell proliferation, an increase in the expression and activity of lipogenic enzymes such as the stearoyl-CoA desaturase (SCD) have been observed in PCa. Sterculic acid, contained in the seed's oil of Malvales, is a natural inhibitor of SCD. The objective of our investigation was to evaluate the effects of sterculic oil (SO) from Sterculia apetala seeds on proliferation, cell cycle and apoptosis in prostate cancer cells. SO was administered to PC3 and LNCaP cells, and to prostate normal cells; cell viability, cell cycle, apoptosis, SCD gene and protein expression and enzymatic activity were analyzed. SO administration (4 mM sterculic acid) diminished cell viability in LNCaP and PC3 cells, arrested cell cycle in G2 and promoted apoptosis. SO diminished SCD enzymatic activity with no effects on gene nor protein expression. Our results suggest that SO might offer benefits as an adjuvant in hormonal and chemotherapy prostate cancer treatments. This is the first study to analyze the effect of SO on cancer cells.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"1308-1321"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01635581.2021.1952442","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39200481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis. 吉非替尼和替莫唑胺对U87MG胶质瘤血管生成的协同作用。

IF 2.9

Nutrition and Cancer Pub Date : 2022-01-01 Epub Date: 2021-07-23 DOI: 10.1080/01635581.2021.1952441

Afshin Karami, Maryam Hossienpour, Ehsan Mohammadi Noori, Mehdi Rahpyma, Khadijeh Najafi, Amir Kiani

{"title":"Synergistic Effect of Gefitinib and Temozolomide on U87MG Glioblastoma Angiogenesis.","authors":"Afshin Karami, Maryam Hossienpour, Ehsan Mohammadi Noori, Mehdi Rahpyma, Khadijeh Najafi, Amir Kiani","doi":"10.1080/01635581.2021.1952441","DOIUrl":"https://doi.org/10.1080/01635581.2021.1952441","url":null,"abstract":"One of the most common and deadly brain tumors is Glioblastoma multiforme (GBM). Due to recent advances in angiogenesis and its related key factors, this process as a hallmark in glioblastoma has attracted more consideration from the research community. Temozolomide (TMZ) as the first-line treatment used to treat GBM but, resistance to TMZ limits its effectiveness and the need for better treatments is still felt. Therefore, we aimed to examine the Synergistic effects of Gefitinib (GFI) in combination with Temozolomide on VEGF and MMPs in glioma cell line (U87MG). Our results displayed that GFI could induce cytotoxic effects in U87MG with IC50 values of 11 μM. U87MG cells produced large amounts of VEGF without any stimuli, and the results showed that GFI in combination with TMZ caused a significant decrease in VEGF production in these cells. In this study, we demonstrated that after treating with TMZ and GFI, there was more decrease in the levels of MMP 2 and 9 secretions in cells than treatment with GFI and TMZ doses alone. This study indicates synergistic effects of GFI plus TMZ against glioma are mediated by the potentiated anti-angiogenesis. Therefore, it can be considered as a promising plan for future studies.","PeriodicalId":501691,"journal":{"name":"Nutrition and Cancer","volume":" ","pages":"1299-1307"},"PeriodicalIF":2.9,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/01635581.2021.1952441","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39212028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2