Journal of Medical Ultrasonics最新文献_第8页

Prospects of perfusion contrast-enhanced ultrasound (CE-US) in diagnosing axillary lymph node metastases in breast cancer: a comparison with lymphatic CE-US 灌注对比增强超声（CE-US）诊断乳腺癌腋窝淋巴结转移的前景：与淋巴CE-US的比较

IF 1.8 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-20 DOI: 10.1007/s10396-024-01444-w

Naoko Mori, Li Li, Masazumi Matsuda, Yu Mori, Shunji Mugikura

{"title":"Prospects of perfusion contrast-enhanced ultrasound (CE-US) in diagnosing axillary lymph node metastases in breast cancer: a comparison with lymphatic CE-US","authors":"Naoko Mori, Li Li, Masazumi Matsuda, Yu Mori, Shunji Mugikura","doi":"10.1007/s10396-024-01444-w","DOIUrl":"https://doi.org/10.1007/s10396-024-01444-w","url":null,"abstract":"<p>Accurate diagnosis of lymph node (LN) metastasis is vital for prognosis and treatment in patients with breast cancer. Imaging 1modalities such as ultrasound (US), MRI, CT, and 18F-FDG PET/CT are used for preoperative assessment. While conventional US is commonly recommended due to its resolution and sensitivity, it has limitations such as operator subjectivity and difficulty detecting small metastases. This review shows the microanatomy of axillary LNs to enhance accurate diagnosis and the characteristics of contrast-enhanced US (CE-US), which utilizes intravascular microbubble contrast agents, making it ideal for vascular imaging. A significant focus of this review is on distinguishing between two types of CE-US techniques for axillary LN evaluation: perfusion CE-US and lymphatic CE-US. Perfusion CE-US is used to assess LN metastasis via transvenous contrast agent administration, while lymphatic CE-US is used to identify sentinel LNs and diagnose LN metastasis through percutaneous contrast agent administration. This review also highlights the need for future research to clarify the distinction between studies involving “apparently enlarged LNs” and “clinical node-negative” cases in perfusion CE-US research. Such research standardization is essential to ensure accurate diagnostic performance in various clinical studies. Future studies should aim to standardize CE-US methods for improved LN metastasis diagnosis, not only in breast cancer but also across various malignancies.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":"8 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140623955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of proteinuria at relapse on shear wave velocity assessed using ultrasound elastography in children with idiopathic nephrotic syndrome 特发性肾病综合征患儿复发时的蛋白尿对使用超声弹性成像技术评估剪切波速度的影响

IF 1.8 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-13 DOI: 10.1007/s10396-024-01455-7

Tomohiko Nishino, Shinya Tomori, Sayaka Ono, Kazuhiro Takahashi, Masakazu Mimaki

{"title":"Effect of proteinuria at relapse on shear wave velocity assessed using ultrasound elastography in children with idiopathic nephrotic syndrome","authors":"Tomohiko Nishino, Shinya Tomori, Sayaka Ono, Kazuhiro Takahashi, Masakazu Mimaki","doi":"10.1007/s10396-024-01455-7","DOIUrl":"https://doi.org/10.1007/s10396-024-01455-7","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Shear wave velocity (SWV) is an ultrasound elastography technique that provides much information for kidney disease assessment. However, the factors that alter SWV are not fully understood; it is unclear whether the variation in SWV seen in proteinuria associated with disease progression is due to tissue or proteinuria. This study investigated the effect of proteinuria on SWV.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>This prospective observational study compared SWV at remission with SWV at relapse in children treated for idiopathic nephrotic syndrome (INS) between April 2020 and December 2023. All relapses without oral steroids during the observation period were measured. SWV at remission was defined as the date closest to relapse during which repeated measurements were taken approximately every 3 months after steroid discontinuation.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Eight patients were treated for INS with a median observation period of 21.9 months (11.8–27.1). Of the 15 relapses, five that met the definition were considered for the study. The median interval between the measurement at relapse and remission was 40 days (11–55). SWV was significantly lower at relapse than remission (2.40 ± 0.20 m/s vs. 2.14 ± 0.15 m/s, <i>P</i> < 0.01).</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>SWV decreased in the presence of severe proteinuria at relapse compared to the remission measurements. Although more cases need to be studied, the decrease in SWV may reflect the mechanism by which protein leaks into the urine, not just a direct change caused by the presence of proteinuria.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":"79 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examination of rapid adjustment system based on screen score obtained using continuous shear wave elastography 根据连续剪切波弹性成像技术获得的筛分结果对快速调整系统进行检验

IF 1.8 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-12 DOI: 10.1007/s10396-024-01439-7

Marie Tabaru, Ren Koda, Hitoshi Shitara, Hirotaka Chikuda, Yoshiki Yamakoshi

{"title":"Examination of rapid adjustment system based on screen score obtained using continuous shear wave elastography","authors":"Marie Tabaru, Ren Koda, Hitoshi Shitara, Hirotaka Chikuda, Yoshiki Yamakoshi","doi":"10.1007/s10396-024-01439-7","DOIUrl":"https://doi.org/10.1007/s10396-024-01439-7","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Continuous shear wave elastography (C-SWE) can be expected to be applied to portable muscle elasticity diagnosis. To establish diagnostic technology, it will be necessary to improve measurement techniques and quantitative measurement accuracy.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>In this study, we investigated two screen scores: the quality index (<i>Q</i>-index), which determines whether the intensity of a power Doppler image is appropriate, and the shear wave propagation direction index (SWDI), which determines the uniformity of shear wave propagation.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>First, we performed numerical simulations with white noise and found that the coefficient of variation of shear wave velocity estimation was less than 5% when the normalized <i>Q</i>-index was greater than 0.27. Furthermore, regarding the SWDI, we clarified the relationship between the standard deviation in shear wave propagation direction and the SWDI. Next, the relationship between the <i>Q</i>-index and coefficient of variation of estimated shear wave velocity was evaluated through experiments using a tissue-mimicking phantom. The results showed that there was a negative correlation between the <i>Q</i>-index and the coefficient of variation, and the fluctuation of the propagation velocity could be inferred from the <i>Q</i>-index. Finally, we showed the results of applying the screen scores to muscle relaxation monitoring and confirmed its usefulness in clinical applications.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>By applying the screen scores, we showed improved stability in speed estimation in C-SWE, and demonstrated the possibility of clinical applicability.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":"20 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of drainage vein of focal nodular hyperplasia using contrast-enhanced ultrasound 利用对比增强超声波评估局灶性结节增生的引流静脉

IF 1.8 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-12 DOI: 10.1007/s10396-024-01451-x

Yukinobu Watanabe, Masahiro Ogawa, Aya Konishi, Seiichiro Suda, Yu Tamura, Masahiro Kaneko, Midori Hirayama, Naoki Matsumoto, Hirofumi Kogure

{"title":"Assessment of drainage vein of focal nodular hyperplasia using contrast-enhanced ultrasound","authors":"Yukinobu Watanabe, Masahiro Ogawa, Aya Konishi, Seiichiro Suda, Yu Tamura, Masahiro Kaneko, Midori Hirayama, Naoki Matsumoto, Hirofumi Kogure","doi":"10.1007/s10396-024-01451-x","DOIUrl":"https://doi.org/10.1007/s10396-024-01451-x","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Identification of drainage vessels is useful for differential diagnosis of hepatic tumors. Direct drainage to the hepatic vein has been reported to occur in focal nodular hyperplasia (FNH), but studies evaluating the drainage veins of FNH are limited. We aimed to investigate the detection rate of the FNH drainage vein and the factors related to visualization of the drainage vein on contrast-enhanced ultrasound (CEUS).</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>Fifty consecutive patients with 50 FNH lesions were retrospectively evaluated in this study. We calculated and compared the detection rate of the FNH drainage vein on CEUS, contrast-enhanced magnetic resonance imaging (CEMRI), and contrast-enhanced computed tomography (CECT), and identified the factors correlated with visualization of the FNH drainage vein on CEUS by using multivariate logistic regression analyses.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Visualization of the drainage vein was confirmed in 31 of 50 lesions (62%) using CEUS, three of 44 lesions (6.8%) using CEMRI, and one of 18 lesions (5.6%) using CECT. The detection rate of the FNH drainage vein on CEUS was significantly higher than that on CEMRI and CECT (<i>p</i> < 0.001). Multivariate analysis identified lesion size (≥ 25 mm) and detection of the spoke-wheel pattern on Doppler US as independent factors for drainage vein detection in FNH.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>Our study showed that rapid FNH drainage to the hepatic vein was observed at a relatively high rate on CEUS, suggesting that CEUS focusing on detection of drainage veins is important for diagnosing FNH.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":"43 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Usefulness of “AcT ratio” in diagnosis of internal carotid artery stenosis: a multicenter, retrospective, observational study AcT比值 "在颈内动脉狭窄诊断中的实用性：一项多中心、回顾性、观察性研究

IF 1.8 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-06 DOI: 10.1007/s10396-024-01409-z

{"title":"Usefulness of “AcT ratio” in diagnosis of internal carotid artery stenosis: a multicenter, retrospective, observational study","authors":"","doi":"10.1007/s10396-024-01409-z","DOIUrl":"https://doi.org/10.1007/s10396-024-01409-z","url":null,"abstract":"<h3>Abstract</h3> <span> <h3>Purpose</h3> <p>The ratio of the internal carotid artery (ICA) to the common carotid artery (CCA), especially the “AcT ratio,” which is a modified measurement method of acceleration time, is useful for diagnosing ICA-origin stenosis. However, previous studies were single-center studies. Therefore, this multicenter, retrospective, cross-sectional study aimed to determine whether a method using the AcT ratio is useful for estimating stenosis rates.</p> </span> <span> <h3>Methods</h3> <p>This study included 461 vessels subjected to carotid artery ultrasonography and evaluation for ICA-origin stenosis via NASCET at four hospitals. The duration from the steep rise point to the inflection point or the first peak was defined as AcT on pulsed wave Doppler. The AcT ratio was calculated as AcT of ICA/AcT of ipsilateral CCA. The AcT ratio and rate of ICA-origin stenosis were analyzed using Pearson's correlation coefficient, simple regression analysis, and ROC curve.</p> </span> <span> <h3>Results</h3> <p>A significant positive correlation was observed between the AcT ratio and NASCET stenosis. NASCET stenosis of ≥ 50% had a sensitivity, specificity, and negative predictive value (NPV) of 70.2%, 71.6%, and 91.5%, respectively, when the cut-off value of the AcT ratio was 1.17. NASCET stenosis of ≥ 70% had a sensitivity, specificity, and NPV of 70.5%, 72.1%, and 95.9%, respectively, when the cut-off value of the AcT ratio was 1.22.</p> </span> <span> <h3>Conclusions</h3> <p>The findings of this multicenter, retrospective, cross-sectional study suggest that the AcT ratio is useful for diagnosing ICA-origin stenosis, especially for diagnosis by exclusion. NASCET stenosis of ≥ 50% was considered unlikely if the Act ratio was ≤ 1.17, whereas NASCET stenosis of ≥ 70% was considered unlikely if it was ≤ 1.22.</p> </span>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":"56 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facilitatory effect of low-pulse repetition frequency ultrasound on release of extracellular vesicles from cultured myotubes 低脉冲重复频率超声波对培养肌管释放细胞外囊泡的促进作用

IF 1.8 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-04 DOI: 10.1007/s10396-024-01429-9

Xiaoqi Ma, Atomu Yamaguchi, Noriaki Maeshige, Kento Tanida, Mikiko Uemura, Fuwen Lu, Hiroyo Kondo, Hidemi Fujino

{"title":"Facilitatory effect of low-pulse repetition frequency ultrasound on release of extracellular vesicles from cultured myotubes","authors":"Xiaoqi Ma, Atomu Yamaguchi, Noriaki Maeshige, Kento Tanida, Mikiko Uemura, Fuwen Lu, Hiroyo Kondo, Hidemi Fujino","doi":"10.1007/s10396-024-01429-9","DOIUrl":"https://doi.org/10.1007/s10396-024-01429-9","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>Extracellular vesicles (EVs) serve as carriers of intracellular factors with therapeutic effects, including tissue regeneration and attenuation of inflammatory responses. The majority of EVs in vivo are derived from skeletal muscle, which is reported to have anti-inflammatory effects. While high-intensity pulsed ultrasound (US) irradiation has been shown to promote EV secretion from myotubes, the impact of pulse repetition frequency, a US parameter affecting pulse length, on EV release remains unclear. This study aimed to investigate the impact of pulse repetition frequency of US on the release of EVs from myotubes.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>C2C12 myoblasts were used in this study. After differentiation into C2C12 myotubes, US was performed for 5 min at an intensity of 3.0 W/cm<sup>2</sup>, duty cycle of 20%, acoustic frequency of 1 MHz, and different pulse repetition frequencies (100 Hz, 10 Hz, or 1 Hz). After 12 h, EVs and cells were collected for subsequent analyses.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>US did not cause a reduction in cell viability across all US groups compared to the control. The concentration of EVs was significantly higher in all US groups compared to the control group. In particular, the highest increase was observed in the 1-Hz group on EV concentration as well as intracellular Ca<sup>2+</sup> level.</p><h3 data-test=\"abstract-sub-heading\">Conclusion</h3><p>This study investigated the effect of three different pulse repetition frequencies of US on the release of EVs from cultured myotubes. It is concluded that a low-pulse repetition frequency of 1 Hz is the most effective for enhancing EV release from cultured myotubes with pulsed ultrasound.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":"50 1","pages":""},"PeriodicalIF":1.8,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140569268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mindset for performing EUS-FNA. 进行 EUS-FNA 的心态。

IF 1.9 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-01 Epub Date: 2024-05-16 DOI: 10.1007/s10396-023-01386-9

Atsushi Kanno

引用次数: 0

Evaluation of renal circulation in heart failure using superb microvascular imaging, a microvascular flow imaging system. 利用超级微血管成像（一种微血管流量成像系统）评估心力衰竭患者的肾循环。

IF 1.9 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-01 Epub Date: 2024-01-18 DOI: 10.1007/s10396-023-01397-6

Shohei Kikuchi, Kiyomi Kayama, Yu Kawada, Shuichi Kitada, Yoshihiro Seo

{"title":"Evaluation of renal circulation in heart failure using superb microvascular imaging, a microvascular flow imaging system.","authors":"Shohei Kikuchi, Kiyomi Kayama, Yu Kawada, Shuichi Kitada, Yoshihiro Seo","doi":"10.1007/s10396-023-01397-6","DOIUrl":"10.1007/s10396-023-01397-6","url":null,"abstract":"<p><strong>Purpose: </strong>Renal circulation evaluation is essential in understanding the cardiorenal relationship in heart failure (HF), and there is a growing interest in imaging techniques that visualize renal circulation. This study aimed to assess the effectiveness of superb microvascular imaging (SMI) in evaluating renal circulation in HF patients.</p><p><strong>Method: </strong>The study included 71 HF patients undergoing cardiac catheterization. Prior to catheterization, renal ultrasound examinations were performed. A control group of 18 subjects without HF was also included. SMI was used to measure the vascular index (VI), which was calculated as the percentage of blood flow signal area in the region of interest. The intrarenal perfusion index (IRPI) was determined as a fluctuation index of VI, reflecting variations in the number of blood cells moving through renal tissue during the cardiac cycle.</p><p><strong>Results: </strong>Using the upper 95% confidence interval of IRPI (0.6) from the control group, HF patients were classified into two groups. Patients with IRPI > 0.6 showed a more congestive profile. Right atrial pressure and biphasic or monophasic Doppler intrarenal flow pattern were independent determinants of IRPI > 0.6. In addition, IRPI remained a significant predictor of estimated glomerular filtration rate (eGFR).</p><p><strong>Conclusion: </strong>The parameter IRPI as variations in SMI signal during the cardiac cycle may be a useful evaluation method for renal perfusion impairment in HF.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"283-292"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic ultrasound-guided fine-needle aspiration for gastrointestinal subepithelial lesions. 内窥镜超声引导下的胃肠道上皮下病变细针穿刺术。

IF 1.9 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-01 Epub Date: 2023-07-25 DOI: 10.1007/s10396-023-01342-7

Takuto Hikichi, Minami Hashimoto, Takumi Yanagita, Tsunetaka Kato, Jun Nakamura

引用次数: 0

Prenatal diagnosis of total anomalous pulmonary venous connection with vertical vein branching into two. 产前诊断肺静脉连接完全异常，垂直静脉一分为二。

IF 1.9 4区医学

Journal of Medical Ultrasonics Pub Date : 2024-04-01 Epub Date: 2024-03-11 DOI: 10.1007/s10396-024-01411-5

Takaaki Maeda, Mikio Morine, Tatsuro Sugimoto, Aki Nagao, Naoto Yonetani, Kenji Hinokio, Kazuhisa Maeda

引用次数: 0