Journal of Medical Ultrasonics最新文献

{"title":"Acute effects of dynamic stretching on the mechanical properties of the triceps surae muscles assessed using shear wave ultrasound elastography.","authors":"Kensuke Oba, Michito Murayama, Sanae Kaga, Mina Samukawa","doi":"10.1007/s10396-025-01589-2","DOIUrl":"https://doi.org/10.1007/s10396-025-01589-2","url":null,"abstract":"<p><strong>Purpose: </strong>Dynamic stretching (DS), characterized by repeated movements through the joint range of motion via antagonist muscle contraction, is thought to reduce muscle stiffness through mechanisms such as reciprocal inhibition. However, whether DS effectively decreases muscle stiffness remains unclear. This study aimed to investigate the acute effects of DS on triceps surae muscle stiffness using shear wave elastography.</p><p><strong>Methods: </strong>Sixteen healthy young adults performed both 120-s DS and control (no stretching) tasks. Shear wave velocities of the medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SOL) muscles were measured as indicators of muscle stiffness before and after DS.</p><p><strong>Results: </strong>Our findings indicated that DS significantly reduced the shear wave velocity in the MG. However, no significant changes were observed in the shear wave velocities of the LG and SOL.</p><p><strong>Conclusion: </strong>DS effectively decreased MG stiffness, with no observed effects in the LG or SOL. These findings highlight inter-muscular variability in response to DS and suggest that DS may be particularly beneficial for targeting stiffness in the MG of the triceps surae muscles.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transient appearance of honeycomb sign: a prenatal finding of intestinal malrotation without volvulus.","authors":"Mika Nara, Yoshihiro Yoshimura, Hiroyuki Goto, Motoyoshi Kawataki, Toshiki Tajima, Hajime Takayasu, Daigo Ochiai","doi":"10.1007/s10396-025-01578-5","DOIUrl":"https://doi.org/10.1007/s10396-025-01578-5","url":null,"abstract":"","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Constructing a predictive model for anti-Müllerian hormone levels in reproductive-age women based on transvaginal three-dimensional ultrasound.","authors":"Xing Si, Xuewei He","doi":"10.1007/s10396-025-01581-w","DOIUrl":"https://doi.org/10.1007/s10396-025-01581-w","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the predictive value of transvaginal three-dimensional (3D) ultrasound imaging parameters for anti-Müllerian hormone (AMH) levels in women of reproductive age.</p><p><strong>Methods: </strong>A retrospective study was conducted on 492 patients who underwent ovarian reserve function assessments at Hangzhou Traditional Chinese Medicine Hospital. The patients were randomly divided into a training set (n = 420) and a validation set (n = 72). All participants underwent transvaginal 3D ultrasound to measure antral follicle count (AFC), ovarian volume (OV), peak systolic flow velocity (PSV), and resistance index (RI). Morning fasting venous blood samples were collected for AMH level measurement. Pearson correlation analysis was used to assess the relationships between age, AFC, OV, PSV, RI, and AMH. Multiple linear regression analysis was used to construct a unified regression model and a grouped regression model. The performance of the models was evaluated by comparing the root mean squared error (RMSE) and mean absolute error (MAE) between predicted and actual values.</p><p><strong>Results: </strong>AMH showed a strong negative correlation with age and a positive correlation with OV, AFC, and PSV. AMH was significantly correlated with AFC and OV (r = 0.844 and 0.759, respectively; both P < 0.05), but only weakly correlated with PSV (r = 0.176, P < 0.05). The RMSE and MAE of the grouped regression prediction model were lower than those of the unified regression model.</p><p><strong>Conclusion: </strong>The grouped regression AMH prediction model developed through multiple linear regression analysis demonstrated favorable performance, enabling accurate individualized prediction of AMH levels, thereby assisting clinicians in evaluating the fertility potential of women of reproductive age.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of attenuation coefficient and sound speed for the diagnosis of liver steatosis: magnetic resonance imaging proton density fat fraction as a reference.","authors":"Mari Hayashi, Katsutoshi Sugimoto, Tatsuya Kakegawa, Hiroshi Takahashi, Hirohito Takeuchi, Yoichi Araki, Kazuhiro Saito, Ryohei Nakayama, Kentaro Sakamaki, Takao Itoi","doi":"10.1007/s10396-025-01575-8","DOIUrl":"https://doi.org/10.1007/s10396-025-01575-8","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the performance of attenuation coefficient (AC) and sound speed (SS) for evaluating liver steatosis in participants who underwent liver fat quantification using magnetic resonance imaging (MRI)-derived proton density fat fraction (PDFF).</p><p><strong>Methods: </strong>Participants with chronic liver disease who underwent both MRI-PDFF (reference standard) and multiparametric ultrasound (US) measurements (such as for AC and SS) were retrospectively enrolled. The associations between the clinical variables and US markers were determined using multivariate linear regression. The diagnostic performance of US markers for detecting steatosis grades was evaluated using the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>Fifty-three participants were included. Patients with metabolic dysfunction-associated steatotic liver disease were predominant (34 out of 53, 53.2%). Multivariate regression analysis revealed significant associations of AC with PDFF (regression coefficient: 0.05, p = 0.003) and body mass index (regression coefficient: 0.0094, p = 0.01). SS was also significantly associated with PDFF (regression coefficient: -12.20, P = 0.03) and body mass index (regression coefficient: -3.08, p = 0.01). The AUCs for AC and SS were 0.88 (95% CI: 0.79-0.97) and 0.70 (95% CI: 0.55-0.84), respectively, for identifying participants with steatosis grade S1 or higher. The performance of detecting steatosis grade S1 or higher was improved and more balanced when AC was ≥0.54 dB/cm/MHz and SS was ≤1536 m/s; the sensitivity and specificity were 72% and 86%, respectively.</p><p><strong>Conclusion: </strong>SS was associated with PDFF and demonstrated fair diagnostic performance in identifying steatosis grade S1 or higher. The combined use of AC and SS may improve the detection of hepatic steatosis.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of liver stiffness measurements using shear wave elastography: impact of skin-to-capsule distance and subcutaneous tissue structure.","authors":"Keisuke Osakabe, Keiko Sugimoto, Hiroji Takai, Yusuke Sano, Keisuke Maeda, Koji Suzuki, Naohiro Ichino","doi":"10.1007/s10396-025-01582-9","DOIUrl":"https://doi.org/10.1007/s10396-025-01582-9","url":null,"abstract":"<p><strong>Purpose: </strong>Shear wave velocity (Vs) measurements can be unstable in individuals with obesity or with a skin-capsule distance (SCD) of ≥ 20 mm. However, instability of Vs has also been observed in cases where SCD is not markedly increased; therefore, the present study aimed to investigate the factors contributing to reduced VsN (net amount of effective shear wave velocity), an index that reflects the reliability of individual Vs measurements.</p><p><strong>Methods: </strong>In total, 317 individuals who underwent community-based health screening were included in this study. We investigated the relationship between VsN and physical findings, laboratory data, SCD, and structure of the SCD (single vs. multilayered) to identify factors associated with decreased VsN.</p><p><strong>Results: </strong>Multiple regression analysis revealed that body fat percentage (β = - 0.135, p = 0.011), SCD (β = - 0.347, p < 0.0001), and the structure of the SC region (β = - 0.295, p < 0.0001) were independently associated with decreased VsN. In cases where the SCD exceeded 20 mm, the VsN within the SCD was significantly lower in the multilayer structural type [52 (28-75)] than in the single-layer structural type [95 (77-99)] (p = 0.004). Furthermore, even when the SCD was 20 mm or less, the VsN within the SCD was significantly lower in the multilayer structure type [80 (68-89)] than in the single-layer structure type [99 (92-100)] (p < 0.0001).</p><p><strong>Conclusion: </strong>The results show that, in addition to SCD thickness, its internal structure reduces the VsN and contributes to Vs measurement instability.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Doppler-inclusive reclassification of fetal growth restriction based on Japanese criterion: a single-center study on perinatal outcomes of pathological and normal small fetuses.","authors":"Sumito Nagasaki, Hikari Kotaki, Makiko Shimabukuro, Junya Sakuma, Mayumi Takano, Masahiko Nakata","doi":"10.1007/s10396-025-01565-w","DOIUrl":"https://doi.org/10.1007/s10396-025-01565-w","url":null,"abstract":"<p><strong>Purpose: </strong>Criteria for diagnosing fetal growth restriction (FGR) vary globally. The Japanese criterion is estimated fetal weight (EFW) below - 1.5 standard deviations, without distinctions based on gestational age or severity. However, some international diagnostic criteria classify FGR using gestational age, Doppler assessments, and growth. While the Japanese criterion is simple and easy to apply, including EFW, gestational age at diagnosis, growth, and Doppler findings can provide a more comprehensive assessment of fetoplacental function. The aims of this study were: [1] to reclassify small fetuses on the Japanese criterion into early FGR, late FGR, or small for gestational age (SGA) groups by applying Doppler-inclusive diagnostic criteria, and [2] compare the perinatal outcomes.</p><p><strong>Methods: </strong>In this retrospective study, FGR diagnosed based on the Japanese criterion between 2017 and 2021 at our hospital were reclassified into early FGR, late FGR, or SGA by applying Doppler-inclusive criteria. Cases not classified as early or late FGR were categorized as SGA. Perinatal, maternal, and neonatal outcomes were analyzed across all groups.</p><p><strong>Results: </strong>Overall, 184 growth-restricted fetuses based on the Japanese criterion-160 cases (42 early FGR, 51 late FGR, and 67 SGA)-were enrolled after excluding 24 cases of fetal malformation. Gestational age at delivery, mode of delivery, and maternal and neonatal complications differed significantly among the groups. The early FGR group showed a significantly higher incidence of preterm birth, emergent Cesarean section, and severe maternal or neonatal complications.</p><p><strong>Conclusions: </strong>FGR with Doppler-inclusive criteria can be better for practical use providing high relevance to perinatal outcome.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Application of four-section approach for prenatal diagnosis of Pierre robin sequence.","authors":"Xiuling Li, Lingyan Liu, Fang Yan, Xiang Yang, Guanghui Xiu, Xudong Dong","doi":"10.1007/s10396-025-01586-5","DOIUrl":"https://doi.org/10.1007/s10396-025-01586-5","url":null,"abstract":"","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of operator variability and technical accuracy of automatic image-based registration in liver fusion imaging.","authors":"Masashi Hirooka, Teruki Miyake, Ryo Yano, Yoshiko Nakamura, Yuki Okazaki, Toyoki Shimamoto, Takao Watanabe, Osamu Yoshida, Yoshio Tokumoto, Masanori Abe, Yoichi Hiasa","doi":"10.1007/s10396-025-01579-4","DOIUrl":"https://doi.org/10.1007/s10396-025-01579-4","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the technical feasibility and performance of automatic image-based registration (IBR) for liver fusion imaging and to identify clinical and anatomical factors affecting registration success.</p><p><strong>Materials and methods: </strong>This prospective study included 84 patients undergoing liver fusion imaging using an ultrasound system with IBR. Three operators with 5, 10, and 25 years of experience (junior, intermediate, and senior), respectively, independently performed IBR. Fusion time and registration error were recorded. Fusion success was defined both globally (success by all or at least one operator) and individually (registration error < 10 mm). Clinical and anatomical factors were assessed. Predictors of failure were identified using multivariable logistic regression with Firth's correction.</p><p><strong>Results: </strong>IBR was successful in all three operators in 86.9% of cases and by at least one operator in 96.4%. The most experienced operator achieved significantly shorter fusion times (median: 15.0 s) and smaller fusion errors (median: 6.0 mm) compared to the less experienced operators. Operator-specific success rates defined as registration error < 10 mm were 45.2%, 60.7%, and 79.8%, respectively (p < 0.001). Subcutaneous tissue depth was the only independent predictor of fusion failure in both multivariable models (OR = 1.13 for all failed, p = 0.033; OR = 0.88 for partial success, p = 0.012). Other clinical factors were not statistically significant.</p><p><strong>Conclusion: </strong>IBR is a highly feasible method that reduces operator dependency in liver fusion imaging compared to conventional methods, though registration accuracy still varies with operator experience.</p><p><strong>Clinical impact: </strong>IBR enables consistent and simplified fusion imaging regardless of operator experience. Its broad applicability may support safer and more efficient ultrasound-guided interventions, especially in resource-limited or time-sensitive settings.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145180292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamic contrast-enhanced ultrasound with quantitative analysis optimizes LI-RADS for hepatocellular carcinoma diagnosis: a multicenter study.","authors":"Ya-Qin Zhang, Xi Wang, Lin-Na Liu, Xin-Yuan Hu, Qing Lu, Bo-Yang Zhou, Han-Sheng Xia, Hong Han, Hui-Xiong Xu, Chong-Ke Zhao","doi":"10.1007/s10396-025-01572-x","DOIUrl":"https://doi.org/10.1007/s10396-025-01572-x","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the value of dynamic contrast-enhanced ultrasound (DCE-US) analysis using the Liver Imaging Reporting and Data System (LI-RADS) to improve the diagnosis of hepatocellular carcinoma (HCC).</p><p><strong>Methods: </strong>This multicenter study retrospectively enrolled consecutive high-risk patients for HCC who underwent contrast-enhanced ultrasound (CEUS) between December 2022 and June 2023. Quantitative CEUS analysis was performed using VueBox^® to obtain diagnostic parameters for HCC. These parameters were used as auxiliary indicators to reassign the LI-RADS categories. The reference standard was pathologic confirmation or composite criteria. The diagnostic performance of LI-RADS with and without quantitative DCE-US parameters was assessed.</p><p><strong>Results: </strong>269 patients (median age, 61 years [interquartile range, 52-69]; 206 men, 63 women) with 269 focal liver lesions (FLLs) (median size, 40 mm [interquartile range, 25-62 mm]) were included. Among the 269 FLLs, 227 were HCC, 31 non-HCC malignancies, and 11 benign lesions. DCE-US analysis showed HCC had higher rise time (RT) and fall time (FT) at the lesion margin than non-HCC malignancies (both P < 0.05) but lower RT and FT than benign lesions (both P < 0.05). RT at the lesion margin (range 17.48 s-21.16 s) serves as an auxiliary indicator for HCC diagnosis. Compared to CEUS LI-RADS, the revised LR-5 improved sensitivity (61.7 vs. 52.8%, P < 0.001) without a significant decrease in specificity (76.2 vs. 83.3%, P = 0.25) for diagnosing HCC.</p><p><strong>Conclusion: </strong>DCE-US quantitative analysis improved the sensitivity for HCC diagnosis without affecting specificity, thereby optimizing the diagnostic performance of CEUS LI-RADS.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound findings suggestive of microscopic extranodal extension in papillary thyroid carcinoma.","authors":"Noriko Miyamoto, Mitsuyoshi Hirokawa, Miyoko Higuchi, Maki Oshita, Makoto Kawakami, Hiroyuki Yamaoka, Makoto Fujishima, Akira Miyauchi, Takashi Akamizu","doi":"10.1007/s10396-025-01573-w","DOIUrl":"https://doi.org/10.1007/s10396-025-01573-w","url":null,"abstract":"<p><strong>Purpose: </strong>Extranodal extension (ENE) of metastatic carcinoma in patients with papillary thyroid carcinoma (PTC) has been associated with an increased risk of recurrent disease, persistent disease, and disease-specific mortality; however, ultrasound findings suggestive of ENE have not been well established. In this study, we aimed to identify ultrasound findings suggestive of microscopic ENE and validate them histologically.</p><p><strong>Methods: </strong>We retrospectively examined the ultrasound and histological findings of 21 PTC patients with microscopic ENE and 46 without ENE.</p><p><strong>Results: </strong>Node matting, irregular shapes, ill-defined jagged border, and perinodal hyperechoic rims were observed in 40.0%, 57.1%, 42.9%, and 57.1% of lymph nodes with ENE, respectively, and the frequencies were significantly higher than those without ENE, with p values less than 0.05, 0.0005, 0.0001, and 0.0001, respectively. The sensitivity and specificity of cases with any one of irregular shapes, ill-defined jagged border, and perinodal hyperechoic rims were 81.0% and 82.6%, respectively. Histologically, node matting, irregular shape, ill-defined jagged border, and a perinodal hyperechoic rim correspond to adhesion between lymph nodes, extensive invasion, minimal invasion, and invasion into adipose tissue, respectively.</p><p><strong>Conclusions: </strong>We would argue that any irregular shape, ill-defined jagged border, and perinodal hyperechoic rim can be accepted as findings indicative of microscopic ENE.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}