JPGN reportsPub Date : 2024-07-04DOI: 10.1002/jpr3.12104
M. Beeri, Tal Dror, Patrice L. Weiss, Judith N. Blinder
{"title":"A multidisciplinary program to wean infants and toddlers from long‐term tube feeding: Lessons learned from a retrospective study","authors":"M. Beeri, Tal Dror, Patrice L. Weiss, Judith N. Blinder","doi":"10.1002/jpr3.12104","DOIUrl":"https://doi.org/10.1002/jpr3.12104","url":null,"abstract":"Children maintain growth and development by ingesting adequate calories and nutrients, typically achieved via oral intake of food and liquids. When unable to eat and drink orally, they need temporary or permanent enteral nutritional support via nasogastric, nasoduodenal, gastrostomy, or jejunostomy tubes. The objectives of this retrospective study are to describe lessons learned from operating a weaning program at ALYN Hospital for over a decade, the characteristics of the patient population (gender, age, medical condition, and type of tube feeding and hospitalization), and which of these characteristics correlate with successful weaning.Data were obtained from the hospital's secure database of 82 infants and toddlers, 37 boys (45.4%) and 45 girls (54.9%) aged 3 months to 10.8 years who took part in a tube feeding intervention from 2011 to 2020. Descriptive and correlational analyses were performed to characterize the participants and their responses to the program.Fifty‐one children (62.2%) were less than 2 years, 26 children (31.7%) were 2–4.11 years, and only 5 children were aged 5 years (6.1%) and older. Fifty‐six children were successfully weaned from tube feeding, 9 children were eventually successful, but the process took longer than anticipated, 11 children were partially weaned and 6 were not successfully weaned.These results are discussed within the context of a successful weaning program related to participant characteristics (medical condition, age, gender, and weight), and subsequent recommendations are offered related to the intervention setting, duration, and intensity; redefining success in weaning and the need for long‐term follow‐up.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141679283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-07-04DOI: 10.1002/jpr3.12106
Sara Al Dogom, Jerapas Thongpiya, Marawan Elmassry, Mark Feist, Meenu Sharma, George Rateb
{"title":"Successful endoscopic submucosal dissection of an esophageal granular cell tumor in a pediatric patient: A case report and a therapeutic insight","authors":"Sara Al Dogom, Jerapas Thongpiya, Marawan Elmassry, Mark Feist, Meenu Sharma, George Rateb","doi":"10.1002/jpr3.12106","DOIUrl":"https://doi.org/10.1002/jpr3.12106","url":null,"abstract":"Esophageal granular cell tumors (GCTs) are rare mesenchymal neoplasms that originate from the Schwann cells of the neural sheath in the esophageal wall. Esophageal GCTs represent approximately 2% of all GCTs. Most cases of esophageal GCT occur in adults with few cases reported in pediatric patients. Although typically benign, these tumors can occasionally exhibit malignant behavior, necessitating timely and appropriate intervention. Traditionally, surgical resection was considered for treatment, nonetheless, considering the invasive nature of such interventions, endoscopic approaches have been developed for diagnosis and treatment. Endoscopic approaches have been shown to lead to serious complications at times, such as incomplete resection or perforation. Here, we present a successful application of endoscopic submucosal dissection in the treatment of an adolescent female patient with esophageal GCT which was discovered during her prior esophagogastroduodenoscopy for vomiting.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141678226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-07-02DOI: 10.1002/jpr3.12105
Christopher Wen Wei Ho, Lynette Suk‐hui Goh, Lay Queen Ng, Charanya Rajan, V. Logarajah, F. K. Chiou
{"title":"Haemostatic spray in the management of acute nonvariceal upper gastrointestinal bleeding in children: A single‐centre experience in Singapore","authors":"Christopher Wen Wei Ho, Lynette Suk‐hui Goh, Lay Queen Ng, Charanya Rajan, V. Logarajah, F. K. Chiou","doi":"10.1002/jpr3.12105","DOIUrl":"https://doi.org/10.1002/jpr3.12105","url":null,"abstract":"Haemostatic spray (HS; Hemospray) is a powder agent for endoscopic haemostasis in patients with acute upper gastrointestinal bleeding (UGIB). It has been shown to be effective and easy to administer. However, published data on efficacy and safety in children remain scarce. Our aim was to describe our experience with the use of HS in the management of UGIB.A retrospective review was conducted of patients aged 0–18 receiving HS for endoscopic haemostasis from January 2017 to December 2021. Information was obtained on demographics, clinical presentation and comorbidities. Outcomes were successful initial haemostasis and rates of re‐bleeding.A total of 25 applications of HS occurred in 23 patients. The median patient age was 8 years (range: 4 months to 16 years). HS was used in 17/25 (68%) applications as monotherapy. Other treatments employed were clip application and adrenaline injection. One hundred per cent initial haemostasis was achieved with three (13.0%) patients who experienced re‐bleeding. All patients tolerated HS applications with no adverse events.Our finding supports the use of HS in the management of UGIB in children. HS, either as monotherapy or in combination with other conventional therapy, could potentially be the treatment of choice in children with UGIB with its excellent feasibility and good safety profile.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"8 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141685084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-06-24eCollection Date: 2024-08-01DOI: 10.1002/jpr3.12101
Alaina Berg, Uzma Rani, Tarah Colaizy, Abigail Smith, James Evans, Mohammad H Murad, Zulfiqar A Bhutta, Aamer Imdad
{"title":"The impact of donating milk on the health of milk donors and their infants: A systematic review and meta-analysis protocol.","authors":"Alaina Berg, Uzma Rani, Tarah Colaizy, Abigail Smith, James Evans, Mohammad H Murad, Zulfiqar A Bhutta, Aamer Imdad","doi":"10.1002/jpr3.12101","DOIUrl":"10.1002/jpr3.12101","url":null,"abstract":"<p><strong>Objectives: </strong>Breast milk is the recommended nutritional source for newborns and has been associated with decreased morbidity in low-birth-weight and preterm infants. In situations where breast milk is not available, donor breast milk is an alternative. Milk banking is becoming increasingly common worldwide to meet this need. Although the benefits of donor breast milk for the recipient infant are well established, the health impact on the breast milk donor and the infant of the breast milk donor is an area of current research. We aim to synthesize and evaluate the available evidence regarding the impact of donating breast milk on the health, lactation, and well-being of the breast milk donor, and the health and growth of the infant of the breast milk donor.</p><p><strong>Methods: </strong>We will search electronic databases, grey literature, and the websites of relevant international organizations. We will include studies that involve lactating women and their infants, healthy or with health conditions, who donate breast milk, without restrictions on study date, language, or study design. If sufficient homogeneity exists between studies, we will complete meta-analyses. We will evaluate the risk of bias using the Risk of Bias tool or the Cochrane Risk of Bias in Non-Randomized Studies tool. We will evaluate the overall certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach.</p><p><strong>Conclusion: </strong>In this systematic review and meta-analysis, we will summarize the current literature regarding the effects of human milk donation on human milk donors and their infants.</p>","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"5 3","pages":"347-352"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322006/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-06-24eCollection Date: 2024-08-01DOI: 10.1002/jpr3.12102
Roba Alwasila, Alaina Berg, Tarah Colaizy, Abigail Smith, James Evans, Mohammad Hassan Murad, Zulfiqar Ahmed Bhutta, Aamer Imdad
{"title":"The impact of storage, handling, and treatment on nutritional quality and safety of animal milk: A protocol for the systematic review and meta-analysis.","authors":"Roba Alwasila, Alaina Berg, Tarah Colaizy, Abigail Smith, James Evans, Mohammad Hassan Murad, Zulfiqar Ahmed Bhutta, Aamer Imdad","doi":"10.1002/jpr3.12102","DOIUrl":"10.1002/jpr3.12102","url":null,"abstract":"<p><strong>Objectives: </strong>Human milk has been shown to reduce severe morbidity in preterm/low-birth-weight infants and is therefore the recommended nutritional source. When infants cannot receive maternal milk, donor human milk (DHM) is recommended. The use of human milk banking facilities is increasing to meet the need for DHM. DHM is unique compared to maternal milk as it must be processed and stored. The processing and storage of animal milk has been more rigorously studied than human milk and can serve as proxy to create DHM banking guidelines.</p><p><strong>Methods and analysis: </strong>We will search electronic databases, grey literature, and the websites of relevant international organizations. We will include studies that evaluated the impact of storage, handling, and treatment on the nutritional quality and safety of animal milk. We will not restrict study date, language, or design. If sufficient homogeneity exists between studies, we will conduct a meta-analysis. We will evaluate the methodological quality of each study using the SYRCLE's (Systematic Review Centre for Laboratory Animal Experimentation) risk of bias tool. (1) We will evaluate the overall certainty of the evidence using the Grading of Recommendations Assessment, Development, and Evaluation approach.</p><p><strong>Conclusion: </strong>In this systematic review and meta-analysis, commissioned by the World Health Organization, we will synthesize the available literature regarding the impact of various storage, handling, and treatment practices on the nutritional quality and safety of animal milk.</p>","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"5 3","pages":"342-346"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-06-24eCollection Date: 2024-08-01DOI: 10.1002/jpr3.12095
Andrew Liman, Linda Koh, Monique Barakat, Marwa Abu El Haija
{"title":"Preoperative esophagogastroduodenoscopy in pediatric bariatric surgery: A summary of the literature.","authors":"Andrew Liman, Linda Koh, Monique Barakat, Marwa Abu El Haija","doi":"10.1002/jpr3.12095","DOIUrl":"10.1002/jpr3.12095","url":null,"abstract":"<p><p>Our objective was to summarize the available literature on the use of preoperative esophagogastroduodenoscopy (EGD) and its impact on management and/or postoperative outcomes in pediatric patients undergoing metabolic and bariatric surgery. We performed a search using PubMed in February 2023 for articles examining EGD and any clinical correlation in pediatric patients undergoing bariatric surgery. Search results were manually reviewed and included in the study if they examined findings of EGD done prior to bariatric surgery and were excluded if they were not primarily done in pediatric or adolescent patients. Our search yielded 549 distinct articles, with a total of four articles remaining after applying inclusion and exclusion criteria. All four studies were retrospective. A total of 244 patients were studied, with an age range of 9-25 years. Of the patients whose respective findings were reported, 21/150 patients (14%) had esophagitis, 55/150 (37%) had gastritis, 55/244 (23%) had <i>Helicobacter pylori</i>, and 18/150 (12%) had duodenitis. There were a total of 60 findings that changed medical management, and one that changed surgical management. A high proportion of positive EGD findings that changed medical management was evident, and one study suggested that mucosal inflammation may be a prognostic indicator for postoperative weight loss. However, there is a paucity of data examining the utility of routine EGD prior to bariatric surgery, specifically in pediatric patients, and more studies are therefore needed to construct the evidence basis for guidelines.</p>","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"5 3","pages":"243-249"},"PeriodicalIF":0.0,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-06-21eCollection Date: 2024-08-01DOI: 10.1002/jpr3.12085
Sarah Orkin, Kathryn Hitchcock, Jennifer Phillips, Emily Romantic, Amiee Trauth, Jacqueline Wessel, Marialena Mouzaki
{"title":"Infant versus noninfant formulas and cow's milk: Transition based on age or weight?","authors":"Sarah Orkin, Kathryn Hitchcock, Jennifer Phillips, Emily Romantic, Amiee Trauth, Jacqueline Wessel, Marialena Mouzaki","doi":"10.1002/jpr3.12085","DOIUrl":"10.1002/jpr3.12085","url":null,"abstract":"<p><p>Infant formulas are meant to be used until 1 year of age, at which point children are transitioned to non-infant formulas or cow's milk, depending on their remaining dietary intake. Noninfant formulas and cow's milk are appropriate for children who have an average weight at that 1-year mark (9-9.5 kg); however, can contribute significant protein and/or electrolytes to children who are underweight for age, particularly if they still rely heavily on formula feeding for their caloric intake. In this short communication, we present several cases of patients who received excessive amounts of nutrients for age following the formula transition at the 1-year mark. We also provide recommendations for clinicians to consider when faced with underweight infants who are meant to be transitioning off infant formulas.</p>","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"5 3","pages":"353-356"},"PeriodicalIF":0.0,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322026/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-06-17eCollection Date: 2024-08-01DOI: 10.1002/jpr3.12099
Shivany Pathania, Rahiya Rehman, Madeleine Ward, Ali Yalcindag, Albert Ross, Michael Herzlinger, Irina Gorbounova
{"title":"An unusual case of pediatric granulomatosis with polyangiitis complicated by splenic infarction presenting as inflammatory bowel disease.","authors":"Shivany Pathania, Rahiya Rehman, Madeleine Ward, Ali Yalcindag, Albert Ross, Michael Herzlinger, Irina Gorbounova","doi":"10.1002/jpr3.12099","DOIUrl":"10.1002/jpr3.12099","url":null,"abstract":"<p><p>We describe a case of granulomatosis with polyangiitis (GPA) in a 7-year-old-male who initially presented with symptoms concerning for Inflammatory bowel disease. GPA is a rare, multisystemic necrotizing vasculitis involving small arteries and veins. The clinical presentation can be variable given its multisystemic involvement but more commonly involves the upper and lower airways and kidneys. This case highlights rare gastrointestinal symptoms of GPA, further complicated by an additional unique finding of splenic infarction. We hope to raise awareness for this rare illness to assist in diagnosis and treatment, as timely induction of remission can reduce significant morbidity and mortality in the pediatric population.</p>","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"5 3","pages":"398-401"},"PeriodicalIF":0.0,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
JPGN reportsPub Date : 2024-06-03DOI: 10.1002/jpr3.12077
Colin Winke, Brandon Moore, Jacob Gelman, Stephan Paul, Audra S. Rouster, Amy Guido
{"title":"A case of Burkitt Lymphoma discovered by digital rectal exam","authors":"Colin Winke, Brandon Moore, Jacob Gelman, Stephan Paul, Audra S. Rouster, Amy Guido","doi":"10.1002/jpr3.12077","DOIUrl":"https://doi.org/10.1002/jpr3.12077","url":null,"abstract":"Burkitt Lymphoma (BL) is an aggressive B‐cell lymphoma predominantly encountered in pediatrics. Sporadic type typically involves the abdomen and/or pelvis. We present an 8‐year‐old Caucasian male with vomiting, weight loss, fatigue, and abdominal pain. An abdominal X‐ray was unremarkable without any acute findings. Pediatric gastroenterology was consulted and recommended esophagogastroduodenoscopy and colonoscopy. A digital rectal exam (DRE) was performed, and a firm lesion was palpated. The colonoscopy was normal. Subsequent magnetic resonance imaging and computed tomography scans revealed a lesion in the left lower quadrant with mass‐like processes involving the porta hepatis and encasing the left distal ureter. Tissue biopsy confirmed BL. The patient completed chemotherapy and achieved remission. This case highlights DRE as a basic physical exam skill in the evaluation of patients with nonspecific gastrointestinal symptoms.","PeriodicalId":501015,"journal":{"name":"JPGN reports","volume":"37 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141270374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}