Journal of Research in Medical Sciences最新文献

{"title":"Comparison of the performance of machine learning algorithms for the task-switching functional magnetic resonance imaging data for distinguishing attention deficit hyperactivity disorder from bipolar disorder.","authors":"Leila Solouki, Soodeh Shahsavari, Hamid Sharini, Amir Hossein Hashemian, Youkhabeh Mohammadian, Hiwa Mohammadi, Behzad Mahaki","doi":"10.4103/jrms.jrms_406_24","DOIUrl":"10.4103/jrms.jrms_406_24","url":null,"abstract":"<p><strong>Background: </strong>Bipolar disorder (BD) and attention deficit hyperactivity disorder (ADHD) are two distinct psychiatric disorders characterized by significant overlap in symptoms, making differential diagnosis challenging. Due to the lack of a definitive test for diagnosing and differentiating these disorders, the present study aimed to accurately diagnose and differentiate between patients with BD and ADHD using the support vector machines (SVM) with radial basis function, polynomial, and mixture kernels, as well as ensemble neural networks, to analyze functional magnetic resonance imaging (fMRI) data.</p><p><strong>Materials and methods: </strong>In this study, 49 individuals with BD and 40 individuals with ADHD were analyzed. A protocol based on fMRI imaging and a switching task was proposed for diagnosing ADHD and BD. The graph theory method calculated the graph criteria using the CONN toolbox in 15 areas of the attention circuit. The effective features were then selected using the genetic algorithm (GA), and finally, the performance of the models was evaluated using four criteria: accuracy (ACC), sensitivity (SE), specificity (SP), and area under the curve (AUC).</p><p><strong>Results: </strong>57 effective and important features were selected as input features by GAs with 99.78% ACC. The performance score of the models showed that the SVM with mixture kernels model performed best among the other algorithms (ACC = 92.1%, SE = 92.6%, SP = 97.3%, and AUC = 0.931).</p><p><strong>Conclusion: </strong>According to the evaluation criteria values, the best model for diagnosing ADHD from BD has been suggested. This approach can be useful in diagnosis, psychological, and psychiatric interventions.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"56"},"PeriodicalIF":1.7,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of an 8-week home-based resistance training and leisure-time physical activity on serum glucagon-like peptide-1 and microRNA-192 levels in children with type 1 diabetes: A randomized clinical trial.","authors":"Maryam Nazari, Vazgen Minasian, Silva Hovsepian","doi":"10.4103/jrms.jrms_582_24","DOIUrl":"https://doi.org/10.4103/jrms.jrms_582_24","url":null,"abstract":"<p><strong>Background: </strong>While numerous studies highlight the significant health benefits of physical activity, there is limited research on the effect of various exercise training in children with type 1 diabetes mellitus (T1DM). The current study aimed to investigate the effects of physical activity on the expression of microRNA (miRNA)-192, serum glucagon-like peptide-1 (GLP-1) level, and some factors related to T1DM in children.</p><p><strong>Materials and methods: </strong>In this randomized clinical trial study, a total of 20 children with T1DM were randomly divided into the following two groups and trained for 8 weeks: home-based resistance training (HBRT) (<i>n</i> = 10, age = 12.6 years) and leisure-time physical activity (<i>n</i> = 10, age = 12.4 years). Metabolic biomarkers, serum levels of miRNA-192, GLP-1, and other relevant measurements were assessed in each patient 48 h before and after completing the 8-week training program.</p><p><strong>Results: </strong>The findings showed that in both the training groups, fasting blood glucose concentrations decreased significantly, and maximum oxygen consumption (VO₂ max) increased significantly (<i>P</i> ≤ 0.05). Furthermore, a significant difference was identified between the cardiovascular endurance (VO₂ max) levels of the two groups, with the HBRT group demonstrating a more substantial improvement. Although increased levels of fasting insulin and decreased levels of glycated hemoglobin were not significant in both the groups (<i>P</i> ≥ 0.05), a significant increase was observed in the GLP-1 serum levels of both the groups and their miRNA-192 levels decreased by 58%-60% (<i>P</i> ≥ 0.05).</p><p><strong>Conclusion: </strong>Encouraging children with T1DM to do appropriate exercise training workouts at home as well as proper physical activities during their leisure time can be effective in reducing potential complications in patients and improving their health.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"58"},"PeriodicalIF":1.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the level of agreement in the measurement of coronary artery calcification among radiology technicians and radiology specialists.","authors":"Maryam Moradi, Awat Feizi, Ebrahim Rafiei, Fateme Sadat Mostafavi","doi":"10.4103/jrms.jrms_559_24","DOIUrl":"https://doi.org/10.4103/jrms.jrms_559_24","url":null,"abstract":"<p><strong>Background: </strong>To investigate the level of agreement in the measurement of coronary artery calcification among radiology technicians and radiology specialists.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted on 544 cases in the Radiology Department of Al-Zahra Hospital in Isfahan in 2021. The archives of heart computed tomography scans were reviewed, and coronary artery calcium scores (CACS) reported by radiology technicians and radiologists were marked and compared.</p><p><strong>Results: </strong>The level of agreement of the score measured by two evaluators in the whole sample is equal to intracluster correlation coefficient = 0.996 (95% confidence interval [CI]: 0.995-0.997) (<i>P</i> < 0.001) and the level of agreement based on calcification categories measured by weighted kappa was 0.968 (95% CI: 0.953-0.982)(<i>P</i> < 0.001), both of which indicate an excellent and significant intensity of agreement.</p><p><strong>Conclusion: </strong>The results of our study demonstrate a high level of agreement regarding CACS between technicians and radiologists.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"57"},"PeriodicalIF":1.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Polyautoimmunity and multiple autoimmune syndromes: A neglected clinical challenge.","authors":"Peyman Mottaghi","doi":"10.4103/jrms.jrms_623_25","DOIUrl":"https://doi.org/10.4103/jrms.jrms_623_25","url":null,"abstract":"","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"55"},"PeriodicalIF":1.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term all-cause mortality rate after ST-elevation myocardial infarction and its predictors: ST Elevation Myocardial Infarction Cohort in Isfahan Study.","authors":"Yasaman Shojaei, Masoumeh Sadeghi, Kamran Mehrabani, Mohammadamin Sadri, Sina Rouhani, Razieh Hassannejad, Hamidreza Roohafza","doi":"10.4103/jrms.jrms_314_24","DOIUrl":"https://doi.org/10.4103/jrms.jrms_314_24","url":null,"abstract":"<p><strong>Background: </strong>ST-elevation myocardial infarction (STEMI) remains a significant global health concern, especially in low- and middle-income regions. This study aimed to identify long-term prognostic factors among STEMI patients, offering insights into improving patient outcomes.</p><p><strong>Materials and methods: </strong>This study represents the 5-year follow-up of STEMI patients in the SEMI Cohort in Isfahan registry, a clinical-based registry of STEMI patients in Isfahan, Iran, from October 2015. All patients with STEMI within 24 h of symptom onset underwent a comprehensive evaluation. The dataset included demographic information, laboratory data, medical history, and clinical in-hospital data. Over 5 years, annual follow-ups were conducted to track hospitalization and patient all-cause mortality. Utilizing univariate and multivariate Cox regression proportional hazard modeling, we aimed to identify predictors of death.</p><p><strong>Results: </strong>In this study, involving 759 patients (621 men and 138 women) with a mean age of 58.92 ± 11.79 years, 158 deaths (21%) with a mean age of 70.33 ± 12.66 years occurred after STEMI. In the multiple model our analysis revealed that the following variables significantly increased all-cause mortality independently: Older age (hazard ratio [HR]: 1.070, <i>P</i> < 0.001), lower body mass index (HR: 0.890, <i>P</i> < 0.001), hypertension status (HR: 2.441, <i>P</i> < 0.001), lower systolic blood pressure at initial presentation (HR: 0.983, <i>P</i> < 0.001), number of affected epicardial territories (HR: 2.979, <i>P</i> < 0.001), lower last ejection fraction before discharge (HR: 0.951, <i>P</i> < 0.001), lower hemoglobin level (HR: 0.747, <0.001), higher plasma glucose level (HR: 1.005, <i>P</i> < 0.001), and in-hospital complications (HR: 7.646, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>This study identified a range of factors that predict STEMI-related mortality. These findings are pivotal for future planning and decision-making regarding appropriate diagnostic and therapeutic strategies during patient follow-up, contributing to improved outcomes in STEMI care.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"53"},"PeriodicalIF":1.5,"publicationDate":"2025-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12646341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145642268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevention of preeclampsia by aspirin consumption in high-risk pregnancies that can be complicated with preeclampsia: A systematic review.","authors":"Somayeh Khanjani, Maryam Hajihashemy, Maryam Hashemi, Minoo Movahedi, Farinaz Farahbod, Sima Aliyari, Fateme Abbasi, Hatav Ghasemi Tehrani","doi":"10.4103/jrms.jrms_565_24","DOIUrl":"10.4103/jrms.jrms_565_24","url":null,"abstract":"<p><strong>Background: </strong>For a long time, it has been proposed that aspirin might have a preventive property to reduce the risk of preeclampsia; however, recent assessments have changed the insights toward this medication. The current qualitative systematic review aims to thoroughly assess the outcomes of treatment with aspirin in high-risk preeclampsia women.</p><p><strong>Materials and methods: </strong>The scope of this study was to evaluate: (1) the preventive role of treatment with aspirin on high-risk pregnancies for preeclampsia, (2) the applied dose on the incidence of preeclampsia, (3) the outcome of using aspirin alone versus in combination with an anticoagulant, and (4) the outcome of aspirin discontinuation on the incidence of preeclampsia. PubMed, Scopus, Web of Science, and Embase databases were searched from January 1, 2015, to December 31, 2023. English-written studies with trial designs (randomized or nonrandomized) assessing the use of aspirin on preeclampsia prevention among high-risk women for this phenomenon were included. Three authors independently surfed the databases and selected the studies; in case of any disagreement, the problem was resolved by the fourth author. Then, the papers were fully screened and those that met the study criteria were individually evaluated. The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials was applied categorizing the studies into low-moderate and high risk of bias.</p><p><strong>Results: </strong>Finally, data from twenty-three studies on 15,764 high-risk preeclampsia individuals with singleton pregnancies were extracted. Fourteen, 4, and 5 studies had low, moderate, and high risk of bias. Aspirin use regardless of its dosage was not remarkably associated with reduced risk of preeclampsia in the majority of studies. Besides, the time of initiation or discontinuation did not affect the outcomes. Moreover, aspirin combination with anticoagulant was not necessarily superior over aspirin alone.</p><p><strong>Conclusion: </strong>Based on our findings, the body of evidence majorly found no remarkable role for prophylactic aspirin use to prevent preeclampsia incidence at any time during pregnancy; however, promising data, particularly in higher doses and earlier initiation of aspirin, have been noted.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"49"},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12536866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of <i>Helicobacter pylori</i> eradication therapy on quality of life and symptoms in osteoarthritis symptoms in infected patients: A nonblinded clinical trial.","authors":"Ghazaleh Heidari, Shahin Asgari-Savadjani, Mohammad Karami-Horestani, Awat Feizi","doi":"10.4103/jrms.jrms_613_24","DOIUrl":"10.4103/jrms.jrms_613_24","url":null,"abstract":"<p><strong>Background: </strong>Osteoarthritis (OA) is a disease whose treatment is essential due to various complications, such as pain, inflammation, and disturbance in patients' quality of life (QOL). This study aimed to determine the effect of <i>Helicobacter pylori</i> eradication therapy on QOL and arthritis symptoms in patients with OA who are infected with <i>H. pylori.</i></p><p><strong>Materials and methods: </strong>In this clinical trial, 62 OA patients were categorized into two groups based on diagnostic tests: <i>H. pylori</i> positive and negative. The negative group received only standard OA treatment, while the positive group underwent eradication therapy in addition to standard treatment. Patients were assessed and compared before, 4 weeks, and 8 weeks after treatment using the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Visual Analog Scale (VAS), and European Quality of Life Questionnaire. Data were analyzed using the SPSS software.</p><p><strong>Results: </strong>Comparison of the two groups revealed a significant reduction in physical function, joint stiffness, pain, total WOMAC, and VAS scores in the <i>H. pylori</i> positive group over the study period (<i>P</i> < 0.05), whereas no significant changes were observed in the negative group (<i>P</i> > 0.05). QOL scores improved significantly in the eradicated group (<i>P</i> < 0.05). Significant improvements were seen between the eradicated and noneradicated subgroups in physical function, pain, total WOMAC, and VAS scores, with more significant improvements in the eradicated group (<i>P</i> < 0.05). After the intervention, self-care and QOL scores differed significantly between the groups, with the eradicated group showing better outcomes (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>In OA patients with <i>H. pylori</i> infection, eradication therapy improves specific symptoms, pain, and QOL.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"48"},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12536865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on published original article - Comparison of endotracheal intubation, laryngeal mask airway, and I-gel in children undergoing strabismus surgery.","authors":"Pallavi Ahluwalia, Bhavna Gupta","doi":"10.4103/jrms.jrms_104_21","DOIUrl":"10.4103/jrms.jrms_104_21","url":null,"abstract":"","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"52"},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12536860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiologic, histopathological, and prognostic analysis of cancer of unknown primary in an Iranian population.","authors":"Mohammad Rayati, Hamzeh Ahmadi, Mitra Heidarpour, Nadia Najafizade, Mehrdad Zeinalian","doi":"10.4103/jrms.jrms_520_24","DOIUrl":"10.4103/jrms.jrms_520_24","url":null,"abstract":"<p><strong>Background: </strong>Cancer of unknown primary (CUP) is characterized by metastatic cancer cells with no identifiable primary tumor despite extensive diagnostics. This study investigates the epidemiologic, histopathological, and prognostic factors in 352 CUP cases in Iran.</p><p><strong>Materials and methods: </strong>This retrospective study reviewed the clinical documents of CUP patients registered in MACSA, a charity-based referral center in central Iran, Isfahan, within 2016-2021. The patients' data were analyzed, and survival associations were assessed using Cox proportional hazards regression models.</p><p><strong>Results: </strong>Altogether 352 CUP patients were included in the study. The mean age at diagnosis was 65.9 ± 14.3 years, with 52.6% being male. Abdominal pain (32.1%) was the most common presentation. Metastatic adenocarcinoma (31.5%) was the most frequent histopathological type, with the liver (48.6%) as the most prevalent metastatic site. Single-site metastasis was seen in 55.4% of patients. Immunohistochemistry, conducted in 40.3% of patients, was inconclusive in identifying the primary site. The median overall survival was 5 months (95% confidence interval [CI]: 4.0-7.0). Multivariable Cox regression analysis showed older age increased risk of death (hazard ratio [HR]: 1.028, 95% CI: 1.019-1.037). Neuroendocrine tumors were linked to a lower risk (HR: 0.553, 95% CI: 0.313-0.978), while metastasis to the liver (HR: 1.382, 95% CI: 1.076-1.774) and pancreas (HR: 2.138, 95% CI: 1.094-4.176) increased mortality risk.</p><p><strong>Conclusion: </strong>This study provides large-scale evaluation of CUP in an Iranian population, revealing its poor prognosis and the limited diagnostic utility of IHC. The findings align with global data and highlight the urgent need for improved diagnosis and treatment to enhance patient outcomes.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"46"},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12536861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between mean HbA1c, HbA1c variability, and severity of coronary artery disease using SYNTAX score in patients with type 2 diabetes.","authors":"Abbas Andishmand, Mohamad Montazeri, Hamed Bahrami","doi":"10.4103/jrms.jrms_305_24","DOIUrl":"10.4103/jrms.jrms_305_24","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery disease (CAD) is a significant complication of type 2 diabetes mellitus (T2DM). The relationship between long-term glycemic variability (GV) and CAD severity remains uncertain. This study aimed to investigate the association between long-term GV and the extent of CAD in individuals with T2DM.</p><p><strong>Materials and methods: </strong>This retrospective cohort study included patients with T2DM who underwent coronary angiography. Mean-HbA1c was calculated for each patient. GV was assessed by measuring the standard deviation (SD) and coefficient of variation (CV) of HbA1c measurements. The severity of coronary artery lesions was evaluated using the SYNTAX scoring system. Linear regression analyses were performed to assess the differences in SYNTAX scores among different mean-HbA1c groups, as well as SD-HbA1c and CV-HbA1c quartiles.</p><p><strong>Results: </strong>A total of 115 diabetic patients were included in the study. The mean-HbA1c cutoff value of 7.5 was derived from the receiver-operating characteristic curve. Fifty-six patients had a mean-HbA1c of 7.5 or lower, whereas 59 patients had a mean-HbA1c above 7.5. Univariate analysis revealed that patients with mean-HbA1c above 7.5 had significantly higher SYNTAX scores compared to those with lower mean-HbA1c levels (12.79 vs. 7.33, <i>P</i> < 0.05). There was no significant correlation observed between SD-HbA1c, CV-HbA1c, and SYNTAX scores in both univariate and multivariate analyses.</p><p><strong>Conclusion: </strong>This study suggests that higher mean-HbA1c levels are associated with increased severity of CAD in individuals with T2DM. However, long-term HbA1c variability, as measured by SD-HbA1c and CV-HbA1c, does not appear to have a significant impact on the severity of CAD.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"30 ","pages":"47"},"PeriodicalIF":1.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12536863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}