Journal of Spinal Cord Medicine最新文献

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Valuing contributions to peer review: A shared responsibility. 评估对同行评审的贡献:共同的责任。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2025-01-17 DOI: 10.1080/10790268.2025.2441085
Carolann Murphy, Florian P Thomas
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引用次数: 0
Return to work post spinal cord injury through a comprehensive rehabilitative program: A case series. 脊髓损伤后通过综合康复计划重返工作岗位:一个案例系列。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2023-11-17 DOI: 10.1080/10790268.2023.2265099
Nakisha C Gutierrez, Niko Fullmer, Stephen Chai, Emily R Rosario
{"title":"Return to work post spinal cord injury through a comprehensive rehabilitative program: A case series.","authors":"Nakisha C Gutierrez, Niko Fullmer, Stephen Chai, Emily R Rosario","doi":"10.1080/10790268.2023.2265099","DOIUrl":"10.1080/10790268.2023.2265099","url":null,"abstract":"<p><strong>Context: </strong>Spinal cord injury (SCI) can impair bodily functions and limit an individual's ability to maintain or gain steady employment. Vocational rehabilitation programs have been shown to effectively facilitate individuals with a SCI to return to work, however, further research is needed on the implementation, outcomes, and feasibility of such programs including with the integration of healthcare.</p><p><strong>Objective: </strong>The objective of this single-group study was to assess the effectiveness of a comprehensive vocational rehabilitation program, as measured by improvements in employment, work confidence, life satisfaction, and quality of life for individuals with a SCI.</p><p><strong>Methods: </strong>Four individuals with a SCI participated in the vocational rehabilitation program. Participants were assigned responsibilities within their department of interest and attended weekly meetings with the vocational rehabilitation team to address barriers, discuss resources and education, and set professional goals. Completion of pre and post-test assessments was required to evaluate the program's impact on participants' work readiness and overall well-being.</p><p><strong>Results: </strong>Each participant worked with an interdisciplinary team on an individualized work-plan (over 100 h of employment) with necessary accommodations for successful rehabilitation. Participants reported beneficial changes in multiple post-program assessment categories including physical, social, and emotional functions, with all reporting a general improvement in physical strength upon completion of the program.</p><p><strong>Conclusion: </strong>Our findings suggest that a comprehensive vocational rehabilitation program can be effective in facilitating individuals with SCI to gain greater functional independence and confidently pursue employment. Further studies are crucial to advance the knowledge required to implement a successful rehabilitative program.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"141-147"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11749289/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136400097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reviewer recognition 2024. 评审认可2024。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2025-01-17 DOI: 10.1080/10790268.2025.2432243
{"title":"Reviewer recognition 2024.","authors":"","doi":"10.1080/10790268.2025.2432243","DOIUrl":"10.1080/10790268.2025.2432243","url":null,"abstract":"","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":"48 1","pages":"3-5"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748995/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Antimicrobial stewardship strategy implementation and impact in acute care spinal cord injury and disorder units. 抗菌药物管理战略的实施和影响在急性护理脊髓损伤和疾病单位。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2023-11-20 DOI: 10.1080/10790268.2023.2277963
Ashley M Hughes, Charlesnika T Evans, Cara Ray, Harveen Kaur, Margaret A Fitzpatrick, Amanda Vivo, Ayokunle A Olagoke, Geneva M Wilson, Katie J Suda
{"title":"Antimicrobial stewardship strategy implementation and impact in acute care spinal cord injury and disorder units.","authors":"Ashley M Hughes, Charlesnika T Evans, Cara Ray, Harveen Kaur, Margaret A Fitzpatrick, Amanda Vivo, Ayokunle A Olagoke, Geneva M Wilson, Katie J Suda","doi":"10.1080/10790268.2023.2277963","DOIUrl":"10.1080/10790268.2023.2277963","url":null,"abstract":"<p><strong>Context: </strong>Antimicrobial Stewardship Programs (ASPs) are crucial to optimizing antibiotic use. ASPs are implemented in the Veterans Health Administration (VAs), but they do not target the needs of populations at high risk for resistant infections, such as spinal cord injury and disorder (SCI/D).</p><p><strong>Objective: </strong>The goal of this study was to assess key ASP leader and SCI/D clinicians' perceived level of implementation and impact of 33 Antimicrobial Stewardship (AS) strategies.</p><p><strong>Method: </strong>SCI/D clinicians and ASP leaders across 24 VA facilities with SCI/D units were surveyed. Participants rated their perceived level of impact (\"high\", \"mild\", \"low\") and perceived level of implementation (\"not\", \"partially\", \"fully\") for 33 AS strategies in SCI/D units in VAs. Strategies were grouped into core elements which they support. We conducted a Fisher's exact test to assess differences between respondent perceptions based on role (SCI/D clinicians versus ASP leaders).</p><p><strong>Results: </strong>AS strategy implementation varied across VA facilities. Of the AS strategies, pre-authorization was perceived to be highly impactful (78%) and fully implemented (82%). SCI/D clinicians and ASP leaders rated AS strategies differently such that SCI/D clinicians were less aware of implementation of AS strategies related to reporting requirements; further, SCI/D clinicians rated strategies which guide treatment duration and which limit <i>C. difficile</i> antibiotic exposure as more impactful than ASP leaders. Ratings for facility-wide and SCI/D unit ratings did not significantly differ for impact or implementation.</p><p><strong>Conclusion: </strong>Implementation practices varied across VA facilities. Future work should implement highly impactful AS strategies according to facility and unit needs.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"112-128"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748977/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pain interference and depressive symptom severity across 10 years in individuals with long-term spinal cord injury. 长期脊髓损伤患者10年疼痛干扰和抑郁症状严重程度
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2023-11-20 DOI: 10.1080/10790268.2023.2263940
Jillian M R Clark, Yue Cao, James S Krause
{"title":"Pain interference and depressive symptom severity across 10 years in individuals with long-term spinal cord injury.","authors":"Jillian M R Clark, Yue Cao, James S Krause","doi":"10.1080/10790268.2023.2263940","DOIUrl":"10.1080/10790268.2023.2263940","url":null,"abstract":"<p><strong>Objective: </strong>To examine change in pain interference and depression over a 10-year time period in individuals with long-term traumatic spinal cord injury (SCI) and to identify the extent to which changes in pain interference over time predicts change in depressive symptoms.</p><p><strong>Design: </strong>Longitudinal analyses of self-report assessment data.</p><p><strong>Setting: </strong>Specialty and university hospitals in the Southeastern and Midwestern United States.</p><p><strong>Participants: </strong>Adults with a history of traumatic SCI (<i>n</i> = 504) who responded to the three most recent data collection periods of the <i>SCI Longitudinal Aging Study</i> (2008 [Time 1], 2013 [Time 2], and 2018 [Time 3]). The participants averaged 59 years of age and 32 years since injury onset at Time 3.</p><p><strong>Interventions: </strong>Not applicable.</p><p><strong>Main outcome measures: </strong>Patient Health Questionnaire (PHQ-9) assessed depressive symptom severity. The 7-item Pain Interference scale from the Brief Pain Inventory assessed pain interference.</p><p><strong>Results: </strong>Over the three study timepoints, the sample averaged moderate levels of pain interference and mild depressive symptom severity. Unconditional linear growth models, reflecting changes in central tendency, indicated that pain interference significantly decreased and depressive symptom severity significantly increased over time. Multiple independent variables random coefficient modeling based on correlations suggested that change in pain interference was positively associated with change in depressive symptom severity over the 10-year study follow-up.</p><p><strong>Conclusion: </strong>Average depressive symptom severity worsened over time. Change in pain interference was positively associated with change in depressive symptom severity. These results point to the complexity of aging related changes in depressive symptoms and pain interference. They further support the need for continued assessment of mood and pain experiences, particularly among individuals reaching aging milestones with SCI.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"31-38"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11749011/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review and meta-analysis use in the field of spinal cord injury research: A bibliometric analysis. 系统回顾和荟萃分析在脊髓损伤研究领域的应用:文献计量学分析。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2023-09-08 DOI: 10.1080/10790268.2023.2251205
Stevan Stojic, Beatrice Minder, Gabriela Boehl, Tania Rivero, Marcel Zwahlen, Armin Gemperli, Marija Glisic
{"title":"Systematic review and meta-analysis use in the field of spinal cord injury research: A bibliometric analysis.","authors":"Stevan Stojic, Beatrice Minder, Gabriela Boehl, Tania Rivero, Marcel Zwahlen, Armin Gemperli, Marija Glisic","doi":"10.1080/10790268.2023.2251205","DOIUrl":"10.1080/10790268.2023.2251205","url":null,"abstract":"<p><strong>Objective: </strong>To subvert issues of low sample sizes and high attrition rates and generate epidemiologically-sound evidence, collaborative research-through international consortia and multi-centric studies-and meta-analysis approaches are encouraged in spinal cord injury (SCI) research. We investigated the use of systematic reviews and meta-analyses (SRMA) methodology in SCI research and evaluated the quality of evidence across publications we identified.</p><p><strong>Methods: </strong>We searched the Web of Science Core Collection database by topic without time or language restrictions through 16 December 2022. We identified additional relevant articles through Embase.com. SRMA including human and animal SCI populations were eligible for inclusion. We analyzed data using Bibliometrix and VOSviewer. We used the JBI tool (former Joanna Briggs Institute) to assess methodological quality of a subset of 50 randomly selected articles.</p><p><strong>Results: </strong>We based our analysis on data from 1'224 documents authored by 5'237 scholars and published in 424 sources between 1985 and 2022. The use of SRMA methodology in the field gained momentum in 2009 and a steady increase followed with an annual growth rate of ≈15%. Our findings indicate major research themes in the field include recovery, SCI management, rehabilitation, and quality of life. Over the past 30 years there has been a shift from SRMA concerning functional recovery, secondary health complications, and quality of life toward biomarkers and neuro-regeneration. The major methodological issues across articles we evaluated included opaquely described search strategies, poorly reported critical appraisals, and insufficiently addressing publication bias. In addition, only one-fifth of articles reported review protocol registration.</p><p><strong>Conclusions: </strong>Our bibliometric analysis clearly shows a rapid increase of SRMA applications in SCI research. We discuss the most important methodological concerns we identified among a randomly selected set of articles and provide guidance for improving adherence to methodological and reporting SRMA guidelines.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"54-64"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10184595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quality of life from the patient perspective at the end of the first rehabilitation after the onset of spinal cord injury/disorder - A qualitative interview-based study. 脊髓损伤/障碍发作后第一次康复结束时患者的生活质量——一项基于定性访谈的研究。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2023-10-11 DOI: 10.1080/10790268.2023.2263235
Natalya Tsoy, Wolf Langewitz, Selina Müri, Seraina Notter, Jürgen Pannek, Marcel W M Post, Lacrimioara-Nicoleta Rednic, Sara Rubinelli, Anke Scheel-Sailer
{"title":"Quality of life from the patient perspective at the end of the first rehabilitation after the onset of spinal cord injury/disorder - A qualitative interview-based study.","authors":"Natalya Tsoy, Wolf Langewitz, Selina Müri, Seraina Notter, Jürgen Pannek, Marcel W M Post, Lacrimioara-Nicoleta Rednic, Sara Rubinelli, Anke Scheel-Sailer","doi":"10.1080/10790268.2023.2263235","DOIUrl":"10.1080/10790268.2023.2263235","url":null,"abstract":"<p><strong>Context: </strong>At present, there is a lack of information concerning patients' perspectives on their quality of life (QoL) after a recently acquired spinal cord injury/disorder (SCI/D).</p><p><strong>Objective: </strong>To explore patients' perspectives on their QoL during their first inpatient rehabilitation after the onset of SCI/D.</p><p><strong>Methods: </strong>Qualitative study. Semi-structured face-to-face interviews were conducted with 20 participants aged 18 years or older at least three months after the onset of SCI/D and two weeks before they were discharged from their first rehabilitation. Audio-recorded interviews were transcribed and analyzed according to the thematic content analysis. Interviewees rated their QoL with the SCI QoL data set.</p><p><strong>Results: </strong>The interviewees judged their satisfaction with life as a whole, their physical and mental health, as relatively high with values between six and eight (with 10 meaning complete satisfaction). They highlighted social aspects, health topics, and the experience of autonomy as relevant to their concept of QoL. The aspects that positively influenced QoL included the level of well-being in the current social and institutional environment, the increased level of energy, strength, and autonomy in daily life, and an improved mental state derived from general positive personal attitudes. In contrast, the social restrictions during the COVID-19 pandemic, physical issues including pain, a lack of progress associated with psychological dissatisfaction, and limitations in personal independence decreased patients' QoL.</p><p><strong>Conclusion: </strong>Since the interviewees described different aspects from the areas of social, health and autonomy as important for their QoL, exploring and addressing these areas should be used to achieve an individualized first rehabilitation.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"129-140"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11748858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41218063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute assessment of spinal cord injury in New South Wales: A retrospective study of current practice in two spinal cord injury referral centers. 新南威尔士州脊髓损伤的急性评估:对两家脊髓损伤转诊中心当前做法的回顾性研究。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2025-01-01 Epub Date: 2023-09-14 DOI: 10.1080/10790268.2023.2247625
Tessa Garside, Ralph Stanford, Oliver Flower, Trent Li, Edward Dababneh, Naomi Hammond, Frances Bass, James Middleton, Jonathan Tang, Jonathan Ball, Anthony Delaney
{"title":"Acute assessment of spinal cord injury in New South Wales: A retrospective study of current practice in two spinal cord injury referral centers.","authors":"Tessa Garside, Ralph Stanford, Oliver Flower, Trent Li, Edward Dababneh, Naomi Hammond, Frances Bass, James Middleton, Jonathan Tang, Jonathan Ball, Anthony Delaney","doi":"10.1080/10790268.2023.2247625","DOIUrl":"10.1080/10790268.2023.2247625","url":null,"abstract":"<p><strong>Introduction: </strong>Interventions provided in the early phases after spinal cord injury (SCI) may improve neurological recovery and provide for best possible functional outcomes. Knowing this relies on early and clear documentation of the level and grade of the spinal cord injury. Guidelines advocate for early documentation of neurological status within 72 h of injury to allow early prognostication and to help guide initial management. It is unclear whether this is current practice in New South Wales (NSW).</p><p><strong>Methods: </strong>Patients with acute SCI who were admitted to two SCI referral centers during 2018-2019 in NSW were included. Data relating to documentation of neurological status, timing of imaging, surgery and transfer to spinal cord injury center were collected and summarized using descriptive statistics.</p><p><strong>Results: </strong>Only 18 percent of patients had an acceptable neurological examination according to the International Standards for Classification of Spinal Cord Injury (ISNCSCI) within 72 h of injury (either not done, or unable to determine the neurological level of injury). At the first neurological examination, the neurological level of injury and grade was unable to be determined in 26.8% of patients and 29.9% of patients respectively. At discharge from acute care and transfer to rehabilitation, the neurological level was undetermined in 28.9% of patients and grade undetermined in 26.8%. ISNCSCI examination was most commonly performed by spinal rehabilitation doctors after patients were discharged from the intensive care unit (ICU).</p><p><strong>Conclusions: </strong>Documentation of neurological level and grade of SCI within 72 h of injury is not being performed in the large majority of this cohort, which may impede evaluation of neurological improvement in response to acute treatment, and hinder prognostication.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"46-53"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11760750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10232573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heavy moxibustion at Sanyin point ameliorates neurogenic bladder dysfunction in spinal cord injury rats through the PI3 K/mTOR pathway. 重度艾灸三阴穴通过pi3k /mTOR通路改善脊髓损伤大鼠神经源性膀胱功能障碍。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2024-12-11 DOI: 10.1080/10790268.2024.2420431
Chunxuan Dong, Qibin Sun, Fangjiang Zheng, Jing Ji, Xiumei Xu, Xingzhang Yao, Decheng Gan
{"title":"Heavy moxibustion at Sanyin point ameliorates neurogenic bladder dysfunction in spinal cord injury rats through the PI3 K/mTOR pathway.","authors":"Chunxuan Dong, Qibin Sun, Fangjiang Zheng, Jing Ji, Xiumei Xu, Xingzhang Yao, Decheng Gan","doi":"10.1080/10790268.2024.2420431","DOIUrl":"https://doi.org/10.1080/10790268.2024.2420431","url":null,"abstract":"<p><strong>Objective: </strong>The present study aims to investigate the effect and mechanism of heavy moxibustion (100 moxa-cone) at Sanyin point (the common point of Yin and kidney) on the function of neurogenic bladder (NB) dysfunction in rats with spinal cord injury (SCI).</p><p><strong>Methods: </strong>Twenty-four male Sprague-Dawley rats were divided into four groups (n = 6): control, NB, NB + Moxibustion, and NB + Moxibustion + YS-49 (PI3 K agonist). The rats in control groups accepted a cut open of the skin, fascia, and muscle. The NB model was established using spinal cord transection. Fourteen days later, animals received heavy moxibustion at Sanyin point for three weeks or/and intraperitoneal administration of YS-49 (a PI3 K agonist). Basso, Beattie, and Bresnahan (BBB) scale, urodynamic parameters, bladder size, and weight were measured. The hematoxylin-eosin staining method was used to observe the histology of the bladder mucosa. Moreover, NB dysfunction after SCI could be restored by autophagy activation and autophagy is mediated by the PI3 K/Akt/mTOR pathway. Therefore, the expressions of autophagy factor (LC3 II/I and p62), PI3 K, and p-mTOR in the bladder mucosa were evaluated by western blotting.</p><p><strong>Results: </strong>Heavy moxibustion treatment relieved the development of NB dysfunction in rats with SCI, with an increase in the bladder voiding efficiency and a decrease in afferent activity during storage in the moxibustion group compared with the NB group. The expression levels of LC3 II/I were markedly elevated by moxibustion, accompanied by a decrease in the levels of p62. YS-49 addition increased the PI3 K and p-mTOR expression which were down-regulated by moxibustion. Importantly, YS-49 reversed the effects of moxibustion on autophagy and bladder function.</p><p><strong>Conclusion: </strong>Heavy moxibustion at Sanyin point exerted its effect on healing-impaired NB dysfunction in rats with SCI, possibly activating autophagy through the PI3 K/mTOR pathway.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteoporosis and osteopenia in young adults with spinal cord injury: The necessity of an early bone mineral density checkup. 脊髓损伤的年轻成人骨质疏松和骨质减少:早期骨密度检查的必要性。
IF 1.8 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2024-12-11 DOI: 10.1080/10790268.2024.2432734
Ahry Lee, Onyoo Kim
{"title":"Osteoporosis and osteopenia in young adults with spinal cord injury: The necessity of an early bone mineral density checkup.","authors":"Ahry Lee, Onyoo Kim","doi":"10.1080/10790268.2024.2432734","DOIUrl":"https://doi.org/10.1080/10790268.2024.2432734","url":null,"abstract":"<p><p><b>Objective:</b> To identify the prevalence and risk factors for low bone density (LBD) in young adults with spinal cord injury (SCI).<b>Design:</b> Retrospective cross-sectional study.<b>Setting:</b> National Rehabilitation Center in Seoul, Korea.<b>Participants:</b> SCI patients aged 20-49 years hospitalized from January 2010 to October 2021.<b>Interventions:</b> Bone mineral density (BMD) was assessed using dual-energy X-ray absorptiometry of the lumbar spine, femoral neck, and total hip.Outcome Measures: Areal BMD, Z-score and T-score of each region and prevalence of LBD.<b>Results:</b> Osteopenia and osteoporosis were diagnosed in 451 (58.2%) and 156 (20.1%) of 775 patients, respectively. Among 181 patients within 3 months of onset, 105 (58%) and 20 (11%) were diagnosed with osteopenia and osteoporosis, respectively. Additionally, the percentage of LBD increased significantly as the time from injury increased. On multivariate analysis, the risk factors for LBD in patients with early SCI within 12 months of onset were female sex (odds ratio [OR] = 2.49; 95% confidence interval [CI], 1.34-4.46; <i>p</i> = 0.002), body mass index (OR = 0.86; 95% CI, 0.81-0.92; <i>p</i> < 0.001), and age (OR = 1.04; 95% CI, 1.01-1.07; <i>p</i> = 0.005). Alcohol or smoking history, etiology, neurological level, or completeness of injury, and the Korean version of the spinal cord independence measure-III score were not significantly correlated with LBD.<b>Conclusions:</b> The prevalence of osteopenia and osteoporosis is high in young adults with SCI. In addition, the diagnosis rate is high in the test performed at the initial stages after injury. Therefore, early bone health monitoring should be performed in young adults with SCI.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-9"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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