Journal of Spinal Cord Medicine最新文献

{"title":"Heavy moxibustion at Sanyin point ameliorates neurogenic bladder dysfunction in spinal cord injury rats through the PI3 K/mTOR pathway.","authors":"Chunxuan Dong, Qibin Sun, Fangjiang Zheng, Jing Ji, Xiumei Xu, Xingzhang Yao, Decheng Gan","doi":"10.1080/10790268.2024.2420431","DOIUrl":"https://doi.org/10.1080/10790268.2024.2420431","url":null,"abstract":"<p><strong>Objective: </strong>The present study aims to investigate the effect and mechanism of heavy moxibustion (100 moxa-cone) at Sanyin point (the common point of Yin and kidney) on the function of neurogenic bladder (NB) dysfunction in rats with spinal cord injury (SCI).</p><p><strong>Methods: </strong>Twenty-four male Sprague-Dawley rats were divided into four groups (n = 6): control, NB, NB + Moxibustion, and NB + Moxibustion + YS-49 (PI3 K agonist). The rats in control groups accepted a cut open of the skin, fascia, and muscle. The NB model was established using spinal cord transection. Fourteen days later, animals received heavy moxibustion at Sanyin point for three weeks or/and intraperitoneal administration of YS-49 (a PI3 K agonist). Basso, Beattie, and Bresnahan (BBB) scale, urodynamic parameters, bladder size, and weight were measured. The hematoxylin-eosin staining method was used to observe the histology of the bladder mucosa. Moreover, NB dysfunction after SCI could be restored by autophagy activation and autophagy is mediated by the PI3 K/Akt/mTOR pathway. Therefore, the expressions of autophagy factor (LC3 II/I and p62), PI3 K, and p-mTOR in the bladder mucosa were evaluated by western blotting.</p><p><strong>Results: </strong>Heavy moxibustion treatment relieved the development of NB dysfunction in rats with SCI, with an increase in the bladder voiding efficiency and a decrease in afferent activity during storage in the moxibustion group compared with the NB group. The expression levels of LC3 II/I were markedly elevated by moxibustion, accompanied by a decrease in the levels of p62. YS-49 addition increased the PI3 K and p-mTOR expression which were down-regulated by moxibustion. Importantly, YS-49 reversed the effects of moxibustion on autophagy and bladder function.</p><p><strong>Conclusion: </strong>Heavy moxibustion at Sanyin point exerted its effect on healing-impaired NB dysfunction in rats with SCI, possibly activating autophagy through the PI3 K/mTOR pathway.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteoporosis and osteopenia in young adults with spinal cord injury: The necessity of an early bone mineral density checkup.","authors":"Ahry Lee, Onyoo Kim","doi":"10.1080/10790268.2024.2432734","DOIUrl":"https://doi.org/10.1080/10790268.2024.2432734","url":null,"abstract":"<p><p><b>Objective:</b> To identify the prevalence and risk factors for low bone density (LBD) in young adults with spinal cord injury (SCI).<b>Design:</b> Retrospective cross-sectional study.<b>Setting:</b> National Rehabilitation Center in Seoul, Korea.<b>Participants:</b> SCI patients aged 20-49 years hospitalized from January 2010 to October 2021.<b>Interventions:</b> Bone mineral density (BMD) was assessed using dual-energy X-ray absorptiometry of the lumbar spine, femoral neck, and total hip.Outcome Measures: Areal BMD, Z-score and T-score of each region and prevalence of LBD.<b>Results:</b> Osteopenia and osteoporosis were diagnosed in 451 (58.2%) and 156 (20.1%) of 775 patients, respectively. Among 181 patients within 3 months of onset, 105 (58%) and 20 (11%) were diagnosed with osteopenia and osteoporosis, respectively. Additionally, the percentage of LBD increased significantly as the time from injury increased. On multivariate analysis, the risk factors for LBD in patients with early SCI within 12 months of onset were female sex (odds ratio [OR] = 2.49; 95% confidence interval [CI], 1.34-4.46; <i>p</i> = 0.002), body mass index (OR = 0.86; 95% CI, 0.81-0.92; <i>p</i> < 0.001), and age (OR = 1.04; 95% CI, 1.01-1.07; <i>p</i> = 0.005). Alcohol or smoking history, etiology, neurological level, or completeness of injury, and the Korean version of the spinal cord independence measure-III score were not significantly correlated with LBD.<b>Conclusions:</b> The prevalence of osteopenia and osteoporosis is high in young adults with SCI. In addition, the diagnosis rate is high in the test performed at the initial stages after injury. Therefore, early bone health monitoring should be performed in young adults with SCI.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-9"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gait recovery in patients with late assessment of incomplete spinal cord injury: A retrospective study in Argentina.","authors":"Marcelo A Gatti, Yamila Dieni, Lucia Yaccuzzi, María E Rivas, Daniela G L Terson de Paleville","doi":"10.1080/10790268.2024.2434304","DOIUrl":"https://doi.org/10.1080/10790268.2024.2434304","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective data analysis study.</p><p><strong>Objectives: </strong>To assess gait recovery rates in subjects with motor incomplete spinal cord injury (SCI) at the start of rehabilitation and to report their gait performance.</p><p><strong>Setting: </strong>Tertiary inpatient Rehabilitation Center in Argentina.</p><p><strong>Methods: </strong>The study analyzed data from 143 individuals with traumatic and non-traumatic SCI (AIS/ASIA Impairment Scale C and D) within 90 days of injury, all non-ambulatory upon admission. Gait status at discharge was evaluated using the 6-minute walk test and the Walking Index for Spinal Cord Injury II (WISCI II). Statistical evaluations utilized Pearson chi-square and Mann-Whitney U-tests. Approval was obtained from Fleni's Ethics Committee.</p><p><strong>Results: </strong>Among the 65 patients with AIS C, 69% regained walking function, compared to 87% of the 74 patients with AIS D (<i>p</i> = 0.01). Walkers had a mean total motor score of 67 (±19) versus 51.7 (±25.5) for non-walkers (<i>p</i> = 0.002), and a total pinprick sensation score of 69.8 (± 27.5) vs. 49.5 (± 29) (<i>p</i> = 0.001). Additionally, 54% of AIS C and 86% of AIS D patients aged ≥ 50 regained walking ability; however, age-related differences were statistically significant only in AIS C group (<i>p</i> = 0,015). AIS D patients walked a mean of 249 meters (±134), while AIS C walked 207 meters (±128) (<i>p</i> = 0.07). The median WISCI II score between the two groups were not statistically significant.</p><p><strong>Conclusions: </strong>Most patients with incomplete motor SCI who participated in inpatient rehabilitation regained walking, with motor score and pinprick sensation correlating to walking ability. Gait performance was comparable between AIS C and D.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-8"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of the Veterans Health Administration Spinal Cord Injuries and Disorders (SCI/D) Registry (VHA SCIDR): Characterization from 1994 to 2022.","authors":"Jennifer L Sippel, Rafer Willenberg, Charlesnika T Evans, Zhiping Huo, Gabriel Escudero, Kevin T Stroupe, Adam Eberhart, Stephen P Burns, Belinda Frazier, I Manosha Wickremasinghe, Bridget M Smith","doi":"10.1080/10790268.2024.2434305","DOIUrl":"https://doi.org/10.1080/10790268.2024.2434305","url":null,"abstract":"<p><strong>Context: </strong>Veterans Health Administration (VHA) maintained a registry of identified and verified cases of US Veterans with spinal cord injuries and disorders (SCI/D) since 1994: VHA SCI/D Registry (VHA SCIDR). Data elements, capture, and storage methods varied over time.</p><p><strong>Objective: </strong>Describe the consolidation and harmonization of historical VHA SCIDR data spanning three decades during its evolution to an automated platform and report population characteristics.</p><p><strong>Methods: </strong>The VHA SCIDR captured data using four distinct acquisition methods over 28 years, including cases of Veterans with SCI/D receiving SCI/D System of Care services, via 25 SCI/D Centers and 122 Spoke Sites throughout the VHA healthcare system. Foundational elements of VHA SCIDR data capture methods, harmonization of data elements with the current automated algorithm, access protocol, and governance structure are described.</p><p><strong>Results: </strong>From Fiscal Years (FYs) 1994 to 2022, VHA SCIDR identified 52,407 Veterans with traumatic or non-traumatic SCI/D, and 96.95% were male, 56.09% White, 16.57% were Black, 1.23% Asian and Pacific Islander, 0.75% Native American, and 25.36% unknown. Traumatic etiology comprised 53.39% of the sample, while 31.75% were non-traumatic, with 14.87% missing etiology classification. Injury category proportions were 5.19% high tetraplegia, 5.83% low tetraplegia, 5.85% high paraplegia, 7.53% low paraplegia, and 23.35% AIS D, with 52.25% missing or unable to be calculated.</p><p><strong>Conclusions: </strong>VHA SCIDR is one of the three largest SCI/D registries in North America and is the case-identification platform for VHA SCI/D operations, program evaluation, and research studies. VHA SCIDR is connected to each Veteran's VHA healthcare data, facilitating big data research.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation of the German language version of the QUAlity of life assessment of spina bifida for adults (QUALAS-A-G).","authors":"Nina Younsi, Raimund Stein, Konrad M Szymanski","doi":"10.1080/10790268.2024.2420141","DOIUrl":"https://doi.org/10.1080/10790268.2024.2420141","url":null,"abstract":"<p><strong>Introduction: </strong>Spina bifida (SB) affects almost all activities in daily life and therefore also health-related quality of life (HRQOL). To assess the HRQOL of adults with SB, a self-reported QUAlity of Life Assessment of Spina bifida in Adults (QUALAS-A) was validated in English. The purpose of this study was to develop and validate a German version of QUALAS-A.</p><p><strong>Methods: </strong>German-speaking adults > = 18 years were recruited at a tertiary center and through an SB association. Two urologists translated the QUALAS-A into German. Face and content validity were assessed by adults with SB. Back-translation into English was performed. QUALAS-A-G was administered online as part of a larger study of sexuality in SB. Internal consistency was verified using Cronbach's alpha. Factor analysis, convergent validity, and differences between groups based on continence were established.</p><p><strong>Results: </strong>A total of 45 adults with SB participated (median age of 29 years old). Domain scores demonstrated no floor and minimal ceiling effects. Cronbach's alpha determined good internal consistency (0.58-0.70). The factor analysis converged to a somewhat different three-factor structure compared to the original version, but otherwise had similar properties to the original. Construct validity revealed moderate associations (<i>r </i>= 0.36-0.65) between QUALAS-A-G domains, indicating they measure different aspects of HRQOL. Adults who were continent of both urine and stool reported higher QUALAS-A-G scores than those who were incontinent.</p><p><strong>Conclusion: </strong>We demonstrated QUALAS-A-G to be reliable and valid in German-speaking adults with SB. The QUALAS-A-G could be a useful tool for communication between adults with SB and medical staff.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-6"},"PeriodicalIF":1.8,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Taking risk to heart: An evaluation of cardiometabolic risk and screening guideline adherence in outpatients with spinal cord injury.","authors":"Luxshmi Nageswaran, Dalton L Wolfe, Laura J Graham, Emma A Bateman","doi":"10.1080/10790268.2024.2420142","DOIUrl":"https://doi.org/10.1080/10790268.2024.2420142","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate cardiometabolic disease (CMD) in outpatients with spinal cord injury/disease (SCI/D). The study aims were to (1) estimate the prevalence of CMD risk factors in a cohort of Canadian adults with SCI/D; (2) assess whether the frequency of CMD screening aligns with evidence-based guidelines; and (3) gain a preliminary understanding of the barriers to CMD screening and/or treatment within a rehabilitation program setting.</p><p><strong>Design: </strong>Quality improvement initiative involving chart review extracting the presence of and frequency of screening for four CMD risk factors (obesity, hypertension, dyslipidemia, diabetes mellitus). Values were compared to evidence-based guidelines for CMD risk identification and management. Root cause analysis and focused interviews were conducted with clinic staff to identify barriers.</p><p><strong>Setting: </strong>Academic, tertiary rehabilitation hospital.</p><p><strong>Participants: </strong>Consecutive outpatients with SCI/D from October 2020 to December 2021 (<i>n</i> = 73).</p><p><strong>Results: </strong>43.8% of outpatients sampled had established CMD (≥3 risk factors) and 94.5% had at least one risk factor. Obesity was the most prevalent (82.2%), followed by dyslipidemia (71.7%), hypertension (46.5%), and diabetes mellitus (34.8%). Hypertension and obesity screening were completed at 14.3% and 10.4% of appointments. The frequency of dyslipidemia and diabetes mellitus screening could not be determined. Eighteen barriers to timely CMD screening and treatment intensification were identified.</p><p><strong>Conclusions: </strong>The prevalence of CMD risk factors in outpatients with SCI/D was high. While approximately two of every five outpatients had established CMD, adherence to screening guidelines was poor. These findings reinforce the need for strategies to improve screening and reduce preventable harm from CMD in this vulnerable population.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.8,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shockwave therapy in persons with a spinal cord injury and spasticity: A multiple single-case experimental design study.","authors":"Boris S G Hellenbrand, Charlotte C M van Laake-Geelen, Henk A M Seelen","doi":"10.1080/10790268.2024.2379067","DOIUrl":"https://doi.org/10.1080/10790268.2024.2379067","url":null,"abstract":"<p><strong>Objective: </strong>To determine whether ESWT is able to safely and positively influence specific ADL activities in people with SCI and spasticity, measured by Goal Attainment Scaling (GAS).</p><p><strong>Study design: </strong>Multiple single-case experimental design with a randomized baseline length.</p><p><strong>Setting: </strong>Rehabilitation centre.</p><p><strong>Subjects: </strong>This study included 11 participants with SCI, aged >18 years (mean (SD) 63 (12.2) years), mean (SD) duration after injury 9 (8.1) years, with hindering spasticity in the upper or lower limb.</p><p><strong>Methods: </strong>During the 3-week treatment phase, radial ESWT in the plantar flexors of the calf (<i>n</i> = 6) or in the flexors of the wrist/hand (<i>n</i> = 5) was applied weekly, followed by a 12-week follow-up phase. The primary outcome measure consisted of the Goal Attainment Scaling (GAS), in which three individual goals were set. Secondary outcome measures included range of joint motion, pain (0-10), 10-m walking test and Van-Lieshout-hand-function-test-for-Tetraplegia (short form).</p><p><strong>Results: </strong>At descriptive level, in total, 28 of the 33 GAS items improved after ESWT and these effects generally were maintained during the follow-up phase. The results of all secondary outcome measures varied. No serious adverse events occurred.</p><p><strong>Conclusions: </strong>In this study, ESWT resulted in improved performance of specific ADL items in most persons with SCI. More research is needed to confirm these results in a larger cohort.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-9"},"PeriodicalIF":1.8,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of bowel management efficacy and subjects' satisfaction in people with spinal cord injury (SCI): An Italian multicenter survey via the MENTOR tool.","authors":"Simone Tiberti, Claudio Pilati, Astrid Bonaccorsi, Luigi G Rizzato, Michele Spinelli, Giulio Del Popolo, Gabriele Righi, Valentina Cicioni, Aquilina Colonna, Ilaria Rosso, Giuseppina Frasca, Luisa De Palma, Antonella Andreottola, Lucia Feltroni, Serena V Capobianco, Giorgio Scivoletto","doi":"10.1080/10790268.2024.2414147","DOIUrl":"https://doi.org/10.1080/10790268.2024.2414147","url":null,"abstract":"<p><strong>Study design: </strong>Observational prospective multicenter study.</p><p><strong>Objectives: </strong>The aim of this study is to evaluate the efficacy of bowel management and subjects' satisfaction by the Monitoring the Efficacy of Neurogenic Bowel Treatment On Response (MENTOR) tool and the impact of demographic and clinical factors on bowel management.</p><p><strong>Methods: </strong>Consecutive patients with SCI were recruited by nine Italian Spinal Units. The MENTOR tool is a three-dimensional questionnaire assessing objective bowel score measures, patient's subjective perceptions, and \"special attention symptoms\"; the combination of these results defines the allocation of each subject into one of three categories reflecting the possible therapeutic recommendations (red for \"recommend change\", yellow for \"further discussion\", and green for \"monitoring\").</p><p><strong>Results: </strong>We recruited 352 subjects with subacute or chronic SCI. The NBD average score was 11.7 ± 7.2 with 69.9% that expresses \"good\" or \"adequate\" satisfaction. 33.1% had one or more \"special attention symptoms (SAS)\". About the MENTOR tool color: 34.6% of the current treatment was adequate (green), 29.7% needed a revaluation (yellow), and 35% required a change (red). While in \"green\" patients the subjective perception coincided with the score, 24% of \"yellow\" patients and 34.4% of \"red\" patients answered they were well managed. None of the clinical or demographic characteristics was associated with patients' satisfaction or belonging to the three color zones.</p><p><strong>Conclusions: </strong>Effective bowel management in subjects with SCI did not correlate with patient characteristics or satisfaction. Many patients have inappropriate bowel management despite their satisfaction and the chronicity of the injury. This disparity calls for a periodic assessment with an objective tool such as MENTOR to identify the individual that requires intervention.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-10"},"PeriodicalIF":1.8,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improving current understanding of cognitive impairment in patients with a spinal cord injury: A UK-based clinician survey.","authors":"Hamish Patel, Daniel Blackburn, Ram Hariharan, Krishnan Padmakumari Sivaraman Nair, Simon M Bell","doi":"10.1080/10790268.2024.2426313","DOIUrl":"https://doi.org/10.1080/10790268.2024.2426313","url":null,"abstract":"<p><strong>Context: </strong>Emerging data suggests that patients with a spinal cord injury (SCI) have a higher risk of developing cognitive impairment. The true incidence of cognitive impairment in this group is unclear due to the difficulty in administering commonly used assessment tools, which are dependent on functional abilities e.g. drawing and writing.</p><p><strong>Methods: </strong>A 16-question online survey, that aims to understand current practices on the assessment of cognition and the limitations of currently available tools, was sent via a Research Network Group to British Association of Spinal Cord Injury Specialists (BASCIS) registered clinicians at each of the 12 Spinal Injuries Centers in the UK and Ireland.</p><p><strong>Results: </strong>41 responses from 11 different SCI centers, with most from clinicians who have worked with SCI patients for over 10 years. 68% felt that there was a higher incidence of cognitive impairment in those with an SCI. However, 15% reported not using tools to screen for cognitive impairment, primarily due to lack of time, lack of guidelines, and physical disabilities affecting the ability to complete tests. When used, the most commonly utilized tools were those that rely on intact hand function.</p><p><strong>Conclusions: </strong>Clinicians report a higher incidence of cognitive impairment in those with an SCI. However, currently used tools are not always appropriate, and patients with impaired hand function may be under-represented or undiagnosed. Further work is needed for a more standardized assessment tool to ensure that these patients receive appropriate diagnosis and management, particularly since cognitive impairment in this group can increase care needs and reduce engagement with rehabilitation.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-7"},"PeriodicalIF":1.8,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shelter-in-place during the COVID-19 pandemic: Impact on secondary health conditions, anxiety, loneliness, social isolation, social connectedness, and positive affect and well-being.","authors":"Melissa L Zahl, Jennifer A Piatt, Cedomir Stanojevic, Shu Cole, Harold D Green","doi":"10.1080/10790268.2024.2420430","DOIUrl":"https://doi.org/10.1080/10790268.2024.2420430","url":null,"abstract":"<p><strong>Context/objective: </strong>The objective of this study was to examine the implications of shelter-in-place (SIP) during the COVID-19 pandemic on secondary health conditions (SHC), loneliness, social isolation, social connectedness, anxiety, and positive affect and well-being (PAWB) among community-dwelling adults with spinal cord injury (SCI).</p><p><strong>Design: </strong>An online exploratory cross-sectional descriptive design.</p><p><strong>Participants: </strong>131 community-dwelling adults with SCI.</p><p><strong>Outcome measures: </strong>UCLA Loneliness Scale, SCI-QOL - Anxiety and PAWB.</p><p><strong>Results: </strong>Respondents were approximately 33 years old, mostly male and Caucasian. More than half reported being married, living with their spouse in a home with modifications, or living in a household of three or more people. More than half reported experiencing more pain during SIP but not experiencing more of any other SHC than before SIP. On average, participants experienced a moderate level of loneliness, severe anxiety, and higher levels of PAWB during SIP.</p><p><strong>Conclusion: </strong>Respondents reported that they experienced more pain, loneliness, and anxiety while at the same time reporting higher PAWB. Future research should focus on understanding the nuances of the seemingly counterintuitive relationship described here to develop better ways to support community-dwelling adults with SCI during public health emergencies and SIP.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-7"},"PeriodicalIF":1.8,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}