Journal of Spinal Cord Medicine最新文献

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The role of sclerostin in spinal cord injury: A scoping review. 硬化蛋白在脊髓损伤中的作用:范围综述。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-17 DOI: 10.1080/10790268.2026.2724661
Joshua Stoikos, Emma Tassinari, David J Allison, Dalton L Wolfe, Janelle Unger
{"title":"The role of sclerostin in spinal cord injury: A scoping review.","authors":"Joshua Stoikos, Emma Tassinari, David J Allison, Dalton L Wolfe, Janelle Unger","doi":"10.1080/10790268.2026.2724661","DOIUrl":"https://doi.org/10.1080/10790268.2026.2724661","url":null,"abstract":"<p><strong>Context: </strong>Sclerostin, an antagonist of the Wnt/β-catenin signaling pathway, serves as a negative regulator of bone formation by inhibiting osteoblast activity. Following spinal cord injury (SCI), disruption of mechanical loading and systemic physiological changes lead to dysregulated sclerostin expression. Despite its known importance, the evidence regarding sclerostin's utility as a predictive biomarker and its potential as a therapeutic target remains unmapped.</p><p><strong>Objective(s): </strong>This scoping review synthesizes the existing evidence on the role of sclerostin in SCI and its implications for bone health outcomes, providing a systematic overview of its associations and addressing an aspect of the existing knowledge gap in our understanding of the mechanisms underlying post-SCI bone loss.</p><p><strong>Methods: </strong>A literature search was conducted in EMBASE, SCOPUS, MEDLINE, and PUBMED. Data were independently extracted, capturing study details, sclerostin measures, and associations with bone health.</p><p><strong>Results: </strong>Cross-sectional studies showed a positive association between sclerostin and bone mineral density in chronic SCI but not in acute SCI. Sclerostin levels also appeared to increase with age. Animal studies indicated that antibody therapy might reduce SCI-related bone loss.</p><p><strong>Conclusions: </strong>The results were heterogeneous, preventing strong conclusions. A positive trend was noted in chronic SCI, but further research is needed, particularly in postmenopausal females and pediatric populations. Pharmacological inhibition of sclerostin shows promise but requires more investigation in human SCI.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-16"},"PeriodicalIF":1.3,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148992321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of kayak ergometer training on trunk control, independence, and cardiovascular fitness in individuals with a spinal cord injury. 皮艇测力训练对脊髓损伤患者躯干控制、独立性和心血管健康的影响。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-11 DOI: 10.1080/10790268.2026.2672832
Marlene A Rodríguez-Barragán, Fabiola M Palomino-Ramos, Wendy M Torres-Serrano, Aída Barrera-Ortíz, Ana V Aguirre-Güemez, Virginia Bueyes-Roiz, Ivett Quiñones-Urióstegui, Alberto I Perez-San Pablo, Paris Jo Velasco-Acosta, Gabriela García-Robledo, Verónica Enríquez-Vázquez, Cynthia E Calderón-Campos, Jimena Quinzaños-Fresnedo
{"title":"Effect of kayak ergometer training on trunk control, independence, and cardiovascular fitness in individuals with a spinal cord injury.","authors":"Marlene A Rodríguez-Barragán, Fabiola M Palomino-Ramos, Wendy M Torres-Serrano, Aída Barrera-Ortíz, Ana V Aguirre-Güemez, Virginia Bueyes-Roiz, Ivett Quiñones-Urióstegui, Alberto I Perez-San Pablo, Paris Jo Velasco-Acosta, Gabriela García-Robledo, Verónica Enríquez-Vázquez, Cynthia E Calderón-Campos, Jimena Quinzaños-Fresnedo","doi":"10.1080/10790268.2026.2672832","DOIUrl":"https://doi.org/10.1080/10790268.2026.2672832","url":null,"abstract":"<p><strong>Context: </strong>To determine the effect of kayak ergometer training on trunk control, cardiorespiratory condition, and independence in individuals with a SCI.</p><p><strong>Design: </strong>Randomized clinical trial.<b>Setting:</b> Third-level hospital.</p><p><strong>Participants: </strong>Individuals with SCI with a neurological level of C8 or below, and 3-12 months since injury.</p><p><strong>Intervention: </strong>A control group received conventional trunk training, and an experimental group received kayak ergometer training. Both groups received five weekly sessions over six weeks.</p><p><strong>Outcome measures: </strong>Neurological status (ISNCSCI), independence (SCIM-III), Trunk Control Test (TCT), life satisfaction (LISAT-9), and a stress test were performed before and after the training.</p><p><strong>Results: </strong>39 individuals were included and randomized to either a conventional trunk training group (n = 18) or an experimental group receiving kayak ergometer training (n = 21). In the experimental group, three participants were eliminated. Therefore, 36 participants completed the study and were included in the data analysis (control: 18; experimental: 18). The majority were men (>72%) with complete injuries, and the majority had lower thoracic injuries (58.4%). At the final measurements, all participants showed improvement in all outcomes following the intervention. We found significant improvements in SCIM-III (<i>p</i> = 0.047) and estimated VO2 (<i>p</i> = 0.045) in the kayak training group, findings that were not statistically significant after Bonferroni correction. Furthermore, compared with the group that received traditional trunk training, the kayak training group showed a trend toward faster, more effective improvement.</p><p><strong>Conclusions: </strong>Kayak ergometer training showed trends toward greater improvements in trunk control, functional independence, and cardiovascular fitness compared with conventional exercise, although differences were not statistically significant after Bonferroni correction.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.3,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148945898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the Spinal Cord Injury Secondary Conditions Scale (SCI-SCS): Comparing self-reports with clinician ratings obtained during routine annual follow-up appointments in a specialized SCI center. 脊髓损伤继发性疾病量表(SCI- scs)的验证:比较自我报告与在专业SCI中心例行年度随访预约中获得的临床医生评分。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-09 DOI: 10.1080/10790268.2026.2721820
Carolina Fellinghauer, Carla Sabariego, Jsabel Hodel, Yannick Rothacher, Inge Eriks Hoogland
{"title":"Validation of the Spinal Cord Injury Secondary Conditions Scale (SCI-SCS): Comparing self-reports with clinician ratings obtained during routine annual follow-up appointments in a specialized SCI center.","authors":"Carolina Fellinghauer, Carla Sabariego, Jsabel Hodel, Yannick Rothacher, Inge Eriks Hoogland","doi":"10.1080/10790268.2026.2721820","DOIUrl":"https://doi.org/10.1080/10790268.2026.2721820","url":null,"abstract":"<p><strong>Context: </strong>Secondary health conditions are highly prevalent among persons with spinal cord injury (SCI) and affect functioning, well-being, and survival. The SCI-Secondary Conditions Scale (SCI-SCS) is widely used to assess problems with secondary health conditions, yet its psychometric properties have not been evaluated, and validity of self-ratings against clinical assessments remains limited.</p><p><strong>Objective: </strong>To evaluate the psychometric properties of the SCI-SCS and validate patient self-reports against ratings of their treating medical doctor.</p><p><strong>Design: </strong>A monocentric study conducted at an SCI center in Switzerland.</p><p><strong>Setting: </strong>The SCI-SCS was completed by patients with SCI (<i>N</i> = 300) prior to routine annual follow-up consultations, while the medical doctor independently rated the same scale.</p><p><strong>Outcome measures: </strong>Psychometric properties of the SCI-SCS, including fit, dimensionality, and local item dependence (LID), were assessed with the Partial Credit Model (PCM). Interrater agreement was evaluated using root mean squared error, Wilcoxon signed-rank tests, differential item functioning, and correlations of Rasch-transformed scores.</p><p><strong>Results: </strong>After accounting for LID, the SCI-SCS demonstrated good fit and unidimensionality. Nine out of 15 items showed good interrater agreement with small effect sizes. However, notable discrepancies were observed for sexual dysfunction, sleep problems, contractures, bladder dysfunction, bowel dysfunction, and circulatory problems. Except for bladder dysfunction, patients tended to report higher problem severity than clinicians.</p><p><strong>Conclusion: </strong>The SCI-SCS is a psychometrically sound tool for assessing secondary conditions in people with SCI; however, self-reports may overestimate severity compared to physician ratings and should be interpreted with caution given differences between clinical judgement and patients' lived experience.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-11"},"PeriodicalIF":1.3,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric spinal cord injury in the Netherlands: Data from the Dutch Spinal Cord Injury Database 2015-2022. 荷兰儿童脊髓损伤:数据来自荷兰脊髓损伤数据库2015-2022。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2692266
Susan J G van Zeelst, Eline W M Scholten, Pauline J M Bernink, Sonja de Groot, Janneke M Stolwijk-Swüste
{"title":"Pediatric spinal cord injury in the Netherlands: Data from the Dutch Spinal Cord Injury Database 2015-2022.","authors":"Susan J G van Zeelst, Eline W M Scholten, Pauline J M Bernink, Sonja de Groot, Janneke M Stolwijk-Swüste","doi":"10.1080/10790268.2026.2692266","DOIUrl":"https://doi.org/10.1080/10790268.2026.2692266","url":null,"abstract":"<p><p><b>Context/Objective:</b> The Dutch Spinal Cord Injury Database (DSCID) collects nationwide data on patients with newly acquired spinal cord injury (SCI) undergoing inpatient rehabilitation in the Netherlands. Pediatric SCI is rare and underrepresented in research. This study aimed to describe the pediatric SCI population, examine differences between age groups (0-8 vs. 9-17 years) and etiology (traumatic (T-SCI) vs. non-traumatic (NT-SCI)), and evaluate the applicability of the DSCID for this population. Design Retrospective observational study using data from DSCID. Setting Dutch inpatient rehabilitation centers.<b>Participants:</b> Children aged 0-17 years with newly acquired SCI admitted between 2015 and 2022. Interventions Not applicable. Outcome Measures Demographics, SCI characteristics, and DSCID data completeness. Applicability assessed by data completeness (>90%) and comment review.<b>Results:</b> Admission data were available for 55 patients; discharge data for 45 (82%). Median age 15 years (IQR 13-17); 67% male; 51% NT-SCI; 44% AIS D; 29% T1-S3, 12% C5-C8, and 15% C1-C4 (All AIS A-C). Children aged 0-8 years had a significantly lower male-to-female ratio. T-SCI patients were significantly older and more often had a high cervical lesion. Admission data were nearly complete (>90%) for pain and skin, whereas sexual function had the lowest completion rate (0% for females).<b>Conclusion:</b> DSCID shows that the NT-SCI and T-SCI groups are equal of size in the Dutch pediatric population. While the DSCID provides useful insight, it is not fully applicable to pediatric SCI. A revised dataset could improve understanding and relevance for pediatric SCI.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-10"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Next steps for a program of research to co-design leisure participation interventions for people with spinal cord injury. A response with future directions. 为脊髓损伤患者共同设计休闲参与干预的下一步研究计划。一个有未来方向的回应。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2721068
Frederik Skovbjerg, Mette Nørtoft, Matthijs Ferdinand Wouda, Peter William Stubbs
{"title":"Next steps for a program of research to co-design leisure participation interventions for people with spinal cord injury. A response with future directions.","authors":"Frederik Skovbjerg, Mette Nørtoft, Matthijs Ferdinand Wouda, Peter William Stubbs","doi":"10.1080/10790268.2026.2721068","DOIUrl":"https://doi.org/10.1080/10790268.2026.2721068","url":null,"abstract":"","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-2"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic significance of the zone of partial preservation (ZPP) within 72 h after complete cervical spinal cord injury: A novel MRI-based approach. 完全性颈脊髓损伤后72小时内部分保存区(ZPP)的预后意义:一种基于mri的新方法。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2699545
Kazuhiro Murotani, Osamu Kawano, Momo Irie, Kazuhiro Hata, Kensuke Kubota, Muneaki Masuda, Takeshi Maeda
{"title":"Prognostic significance of the zone of partial preservation (ZPP) within 72 h after complete cervical spinal cord injury: A novel MRI-based approach.","authors":"Kazuhiro Murotani, Osamu Kawano, Momo Irie, Kazuhiro Hata, Kensuke Kubota, Muneaki Masuda, Takeshi Maeda","doi":"10.1080/10790268.2026.2699545","DOIUrl":"https://doi.org/10.1080/10790268.2026.2699545","url":null,"abstract":"<p><strong>Objectives: </strong>To investigate the prognostic value of the Zone of Partial Preservation (ZPP) within 72 h after cervical spinal cord injury (CSCI) with the American Spinal Injury Association Impairment Scale (AIS) A, and to examine the utility of combining magnetic resonance imaging (MRI) findings with ZPP assessment.</p><p><strong>Study design: </strong>A retrospective case series.</p><p><strong>Setting: </strong>Our institute.</p><p><strong>Participants/methods: </strong>The study participants were seventy patients with an initial diagnosis of complete CSCI within 72 h after injury. The impact of sensory or motor ZPP lengths on the rates of conversion to AIS B/C/D and sensory and motor score recovery at three months after injury was investigated. MRI-based sensory/motor ZPP length was defined as the number of segments between the sensory/motor ZPP and the presumptive primary injured segment of the spinal cord inferred from MRI, and its relevance was also investigated.</p><p><strong>Results: </strong>A total of 9 improved to AIS B, 6 to C, and 1 to D. Sensory ZPP length ≥ 12, and MRI-based sensory ZPP length ≥ 10 were predictive of conversion to AIS C/D with an odds ratio of 18.5 (95% CI, 2.2-154.0, <i>p</i> < 0.05). Significantly greater motor score gain was demonstrated in individuals with longer lengths of MRI-based sensory ZPP (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Long sensory ZPP length within 72 h after injury could be a prognostic factor of conversion to AIS C/D and motor score gain in individuals with sensorimotor complete CSCI. ZPPs could be more useful for predicting recovery potential when combined with MRI findings.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-8"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exercise-based interventions for pain management in individuals with spinal cord injury: A scoping review. 以运动为基础的干预措施对脊髓损伤患者的疼痛管理:范围综述。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2721065
Chittaranjan Mishra, Sivakumar Ramachandran, G Shankar Ganesh, Patitapaban Mohanty, Visvanathan Krishnaswamy, Sanghamitra Pati, Prakash Kumar Sahoo, Pramod Kumar Parida
{"title":"Exercise-based interventions for pain management in individuals with spinal cord injury: A scoping review.","authors":"Chittaranjan Mishra, Sivakumar Ramachandran, G Shankar Ganesh, Patitapaban Mohanty, Visvanathan Krishnaswamy, Sanghamitra Pati, Prakash Kumar Sahoo, Pramod Kumar Parida","doi":"10.1080/10790268.2026.2721065","DOIUrl":"https://doi.org/10.1080/10790268.2026.2721065","url":null,"abstract":"<p><strong>Context: </strong>spinal cord injury (SCI) can cause significant pain through its effects on nociceptive and neuropathic pathways, reducing quality of life. Various forms of exercise-based rehabilitation have been developed; however, findings from previous studies examining their effectiveness remain inconsistent across different pain types in individuals with SCI.</p><p><strong>Objective: </strong>The primary aim of this scoping review was to map the available evidence on exercise-based interventions used for pain management in individuals with SCI and identify existing research gaps.</p><p><strong>Methods: </strong>A literature search was conducted across MEDLINE, Embase, Scopus, and Web of Science for studies published from January 2000 to December 2025. Studies involving adults with SCI experiencing pain who participated in structured exercise programs were included. Data were extracted and descriptively synthesized by pain type and exercise modality.</p><p><strong>Results: </strong>Exercise therapies, including strengthening, aerobic training, functional electrical stimulation (FES), robotic or locomotor training, and mind-body approaches, were examined. Several studies reported favorable outcomes for movement-based interventions in reducing shoulder pain. However, findings related to aerobic exercise for general or neuropathic pain were mixed. Although emerging approaches such as virtual reality and mind-body therapies have been explored, the overall evidence remains limited and inconsistent, indicating that more rigorous research is necessary to determine their effectiveness in pain management.</p><p><strong>Conclusion: </strong>Current evidence indicates that exercise-based interventions have been most frequently investigated for musculoskeletal shoulder pain, while evidence addressing neuropathic pain remains limited. High-quality studies with standardized methodologies are needed.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-20"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of virtual reality technology on functional recovery and activities of daily living in patients with spinal cord injury: A meta-analysis of randomized controlled trials. 虚拟现实技术对脊髓损伤患者功能恢复和日常生活活动的影响:随机对照试验的荟萃分析。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2724660
Song Hu, Jiaju Zhu, Wenpeng Liu, Fengjiao Wang, Jia Liu, Xiaoxue Gao, Yong Zhi, Daehee Kim
{"title":"Effects of virtual reality technology on functional recovery and activities of daily living in patients with spinal cord injury: A meta-analysis of randomized controlled trials.","authors":"Song Hu, Jiaju Zhu, Wenpeng Liu, Fengjiao Wang, Jia Liu, Xiaoxue Gao, Yong Zhi, Daehee Kim","doi":"10.1080/10790268.2026.2724660","DOIUrl":"https://doi.org/10.1080/10790268.2026.2724660","url":null,"abstract":"<p><strong>Context: </strong>Virtual reality (VR) has been increasingly applied in neurorehabilitation, but its effectiveness in patients with spinal cord injury (SCI) remains unclear.</p><p><strong>Objective: </strong>To systematically review the effect of virtual reality (VR) on motor function and activities of daily living (ADL) in patients with spinal cord injury (SCI).</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) evaluating the effects of VR on motor function and activities of daily living (ADL) in patients with SCI were retrieved from PubMed, Embase, Cochrane Library, Web of Science, CNKI, CBM, WanFang, and VIP databases from the establishment of the database to January 2026. Meta-analysis was conducted using RevMan 5.3 software.</p><p><strong>Results: </strong>A total of 20 RCTs were included, comprising 5 immersive VR studies (25.0%), 2 semi-immersive VR studies (10.0%), and 13 non-immersive VR studies (65.0%), involving 662 patients with SCI, including 120 patients with complete SCI, 461 patients with incomplete SCI, and 81 patients from mixed complete/incomplete SCI samples. Meta-analysis showed that, compared with the control group, VR significantly improved lower-limb motor function (ASIA: MD = 5.62, 95% CI [1.93, 9.31], P = 0.003), walking function (FAC: MD = 0.85, 95% CI [0.69, 1.01], P < 0.001), balance function (BBS: MD = 5.47, 95% CI [4.34, 6.59], P < 0.001; mFRT: MD = 3.68, 95% CI [2.47, 4.89], P < 0.001), and ADL (BI: MD = 5.75, 95% CI [3.66, 7.84], P < 0.001). SCIM mobility showed a possible improvement (MD = 3.82, 95% CI [0.76, 6.89], P = 0.01), whereas the SCIM total score was not statistically significant. VR also shortened 10MWT completion time (MD = -3.14, 95% CI [-4.83, -1.45], P < 0.001) and TUGT completion time (MD = -3.56, 95% CI [-4.66, -2.47], P < 0.001). No significant differences were found in upper-limb motor function (FIM, MI, MB, and ARAT).</p><p><strong>Conclusion: </strong>Compared with conventional therapy, VR may improve lower-limb motor function, walking function, balance function, and ADL-related outcomes in patients with SCI. However, current evidence is insufficient to demonstrate the superiority of VR over conventional therapy for upper-limb rehabilitation in SCI.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-26"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of combined electrical muscle stimulation and blood flow restriction in individuals with spinal cord injury. 联合电肌肉刺激和血流限制对脊髓损伤个体的影响。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2719089
Tiffany L Adams, Lauren E Hopps, Abby R Fleming, Hayley V MacDonald, Brett C Bentley, Brent Hardin, Jacob A Mota, Lee J Winchester
{"title":"Effects of combined electrical muscle stimulation and blood flow restriction in individuals with spinal cord injury.","authors":"Tiffany L Adams, Lauren E Hopps, Abby R Fleming, Hayley V MacDonald, Brett C Bentley, Brent Hardin, Jacob A Mota, Lee J Winchester","doi":"10.1080/10790268.2026.2719089","DOIUrl":"https://doi.org/10.1080/10790268.2026.2719089","url":null,"abstract":"<p><strong>Context/objective: </strong>Electrical muscular stimulation (EMS) and blood flow restriction (BFR) individually show promise in spinal cord injury (SCI) rehabilitation, but their combined application in the lower extremities has not been systematically evaluated in an SCI population. This study evaluates the efficacy of combined EMS and BFR (EMS + BFR) in individuals with spinal cord injury (SCI) and characterizes acute hemodynamic responses.</p><p><strong>Design: </strong>Randomized, repeated-measures experimental design.</p><p><strong>Setting: </strong>University of Alabama Exercise Physiology Laboratory.</p><p><strong>Participants: </strong>Ten wheelchair users with SCI below T6.</p><p><strong>Interventions: </strong>Three counterbalanced 20-minute conditions were applied: BFR (40% arterial occlusion pressure [AOP]), EMS, and combined EMS + BFR.</p><p><strong>Outcome measures: </strong>Pre- and post-intervention assessments: heart rate (HR), blood pressure (BP), blood lactate ([La<sup>+</sup>]), posterior tibial artery blood flow and diameter, and vastus medialis cross-sectional area with continuous hemodynamic monitoring for autonomic dysreflexia (AD).</p><p><strong>Results: </strong>No adverse events occurred. EMS + BFR produced mild, manageable hemodynamic responses with a significant main effect of interaction for systolic BP and mean arterial pressure (P < 0.05), with differences between conditions for SBP (P < 0.05). Significant main effect of time for HR (P < 0.05) was found. Baseline milliamperage required to elicit rectus femoris contraction correlated negatively with SCI location (r = -0.715, P < 0.05).</p><p><strong>Conclusion: </strong>No significant pressor response occurred, and there was no significant vascular or muscle swelling; the intervention was well tolerated at 40% AOP. Findings support the safety and potential clinical utility of EMS + BFR in individuals with SCI below the T6 level and provide a foundation for future investigations at higher occlusion pressures.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-14"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Commentary on "Enhancing leisure participation in spinal cord injury rehabilitation: A co-design study": Opportunities for strengthening intervention development. 对“加强休闲参与脊髓损伤康复:一项共同设计研究”的评论:加强干预发展的机会。
IF 1.3 4区 医学
Journal of Spinal Cord Medicine Pub Date : 2026-09-08 DOI: 10.1080/10790268.2026.2721069
Etika Rana
{"title":"Commentary on \"Enhancing leisure participation in spinal cord injury rehabilitation: A co-design study\": Opportunities for strengthening intervention development.","authors":"Etika Rana","doi":"10.1080/10790268.2026.2721069","DOIUrl":"https://doi.org/10.1080/10790268.2026.2721069","url":null,"abstract":"","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"1-2"},"PeriodicalIF":1.3,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148913535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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