RETRACTED ARTICLE: Administration of methylprednisolone do not affect the spinal scar component of spinal cord injury.

IF 1.8 4区 医学 Q3 CLINICAL NEUROLOGY
Journal of Spinal Cord Medicine Pub Date : 2025-07-01 Epub Date: 2024-08-21 DOI:10.1080/10790268.2024.2352929
Xin Liu, Yang Xu, Yangyang Wang, Xia Peng, Jiao Jian, Xuefang Wang, Tinghua Wang
{"title":"RETRACTED ARTICLE: Administration of methylprednisolone do not affect the spinal scar component of spinal cord injury.","authors":"Xin Liu, Yang Xu, Yangyang Wang, Xia Peng, Jiao Jian, Xuefang Wang, Tinghua Wang","doi":"10.1080/10790268.2024.2352929","DOIUrl":null,"url":null,"abstract":"<p><p>We, the Editors and Publisher of the journal <i>The Journal of Spinal Cord Medicine</i>, have retracted the following article:Liu, X., Xu, Y., Wang, Y., Peng, X., Jian, J., Wang, X., & Wang, T. (2024). Administration of methylprednisolone do not affect the spinal scar component of spinal cord injury. <i>The Journal of Spinal Cord Medicine</i>, 1-10. https://doi.org/10.1080/10790268.2024.2352929Following publication, in November 2024, the authors notified the journal that they had identified areas in the article which required improvement, and requested retraction.Upon investigation by the journal, significant concerns were identified regarding the animal model and the integrity of Figure(s) 2 and 4.When approached for an explanation following their request to retract the article, the authors did not respond.As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed.We have been informed in our decision-making by our editorial policies and the COPE guidelines.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as 'Retracted'.</p>","PeriodicalId":50044,"journal":{"name":"Journal of Spinal Cord Medicine","volume":" ","pages":"745-754"},"PeriodicalIF":1.8000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Spinal Cord Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/10790268.2024.2352929","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/21 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

We, the Editors and Publisher of the journal The Journal of Spinal Cord Medicine, have retracted the following article:Liu, X., Xu, Y., Wang, Y., Peng, X., Jian, J., Wang, X., & Wang, T. (2024). Administration of methylprednisolone do not affect the spinal scar component of spinal cord injury. The Journal of Spinal Cord Medicine, 1-10. https://doi.org/10.1080/10790268.2024.2352929Following publication, in November 2024, the authors notified the journal that they had identified areas in the article which required improvement, and requested retraction.Upon investigation by the journal, significant concerns were identified regarding the animal model and the integrity of Figure(s) 2 and 4.When approached for an explanation following their request to retract the article, the authors did not respond.As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article. The corresponding author listed in this publication has been informed.We have been informed in our decision-making by our editorial policies and the COPE guidelines.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as 'Retracted'.

使用甲基强的松龙不会影响脊髓损伤的脊髓疤痕部分。
目的:本研究旨在评估甲基强的松龙(MP)对脊髓损伤(SCI)后瘢痕构成的影响:本研究旨在评估甲基强的松龙(MP)对脊髓损伤(SCI)后瘢痕构成的影响:设计:40 只成年 Sprague Dawley 大鼠接受脊髓右半切开术:干预措施:将大鼠随机分为两组:载体组和 MP 组。MP组大鼠连续7天腹腔注射30毫克/千克剂量的MP,而载体组大鼠腹腔注射生理盐水作为对照。每周使用巴索-巴蒂-布雷斯纳汉试验(BBB)评分和水平阶梯行走试验对大鼠模型的后肢表现进行评估。通过免疫荧光染色确定疤痕成分的变化,并采用轴突再生试验评估抑制条件下的再生情况:结果:与对照组相比,MP 组大鼠在损伤后 7 天的 BBB 评分明显提高,但这种提高并不一致。此外,MP 组大鼠的水平阶梯行走能力并没有逐步改善。值得注意的是,经 MP 治疗后,损伤区域的瘢痕成分含量没有发生明显变化,经 MP 治疗的神经元轴突长度与载体组相比也没有明显延长:我们的研究结果表明,服用 MP 并不能有效增强后肢运动功能,也不能促进 SCI 后瘢痕环境中神经元轴突的生长。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Journal of Spinal Cord Medicine
Journal of Spinal Cord Medicine 医学-临床神经学
CiteScore
4.20
自引率
5.90%
发文量
101
审稿时长
6-12 weeks
期刊介绍: For more than three decades, The Journal of Spinal Cord Medicine has reflected the evolution of the field of spinal cord medicine. From its inception as a newsletter for physicians striving to provide the best of care, JSCM has matured into an international journal that serves professionals from all disciplines—medicine, nursing, therapy, engineering, psychology and social work.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信