Alexandra L Clark, Anny Reyes, Jordana Breton, Melissa Petersen, Sid O'Bryant, Stephanie M Grasso
{"title":"Heterogeneity in cognitive profiles of monolingual and bilingual Hispanic/Latino older adults in HABS-HD.","authors":"Alexandra L Clark, Anny Reyes, Jordana Breton, Melissa Petersen, Sid O'Bryant, Stephanie M Grasso","doi":"10.1017/S1355617724000547","DOIUrl":"https://doi.org/10.1017/S1355617724000547","url":null,"abstract":"<p><strong>Objective: </strong>The present study characterized heterogeneity in the cognitive profiles of monolingual and bilingual Latino older adults enrolled in the HABS-HD.</p><p><strong>Methods: </strong>A total of 859 cognitively unimpaired older adults completed neuropsychological testing. Raw scores for cognitive tests were converted to <i>z</i>-scores adjusted for age, education, sex, and language of testing. A latent profile analysis (LPA) was conducted for monolingual and bilingual speaker groups. A series of 2-5 class solutions were examined, and the optimal model was selected based on fit indices, posterior probabilities, proportion of sample sizes, and pattern of scores. Identified classes were compared on sociodemographic, psychosocial, and health characteristics.</p><p><strong>Results: </strong>For the monolingual group (<i>n</i> = 365), a 3-class solution was optimal; this consisted of a <i>Low Average Memory</i> group with low average verbal memory performances on the SEVLT Total Learning and Delayed Recall trials, as well as an <i>Average Cognition</i> group and a <i>High Average Cognition</i> group. For the bilingual group (<i>n</i> = 494), a 3-class solution was observed to be optimal; this consisted of a <i>Low Average Memory</i> group, with low average verbal memory performances on the learning and delayed recall trials of Logical Memory; a <i>Low Average Executive</i> group, where performance on Trails A and B and Digit Substitution were the lowest; and a <i>High Average Cognition</i> group, where performance was generally in the high average range across most cognitive measures.</p><p><strong>Conclusions: </strong>Cognitive class solutions differed across monolingual and bilingual groups and illustrate the need to better understand cognitive variability in linguistically diverse samples of Latino older adults.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elke Butterbrod, Dominique M J van den Heuvel, Pia Zevenhoven, Lisa Waterink, Mardou van Leeuwenstijn, Roos J Jutten, Wiesje M van der Flier, Sietske A M Sikkes
{"title":"Tele-neuropsychology in memory clinic settings: Reliability and usability of videoconference-based neuropsychological testing.","authors":"Elke Butterbrod, Dominique M J van den Heuvel, Pia Zevenhoven, Lisa Waterink, Mardou van Leeuwenstijn, Roos J Jutten, Wiesje M van der Flier, Sietske A M Sikkes","doi":"10.1017/S1355617724000432","DOIUrl":"https://doi.org/10.1017/S1355617724000432","url":null,"abstract":"<p><strong>Objective: </strong>Neuropsychological assessment through VideoTeleConferencing (VTC) can help improve access to diagnostic and follow-up care in memory clinics. This study investigated the stability of performance on VTC assessment in relation to in-person assessment using a test-retest design and explored user experiences of VTC assessment.</p><p><strong>Materials and methods: </strong>Thirty-one patients (62 ± 6.7 years, 45% female, 58% Subjective Cognitive Decline, 42% Mild Cognitive Impairment/dementia diagnosis) were included from the Amsterdam Dementia Cohort between August 2020 and February 2021. Patients underwent a face-to-face neuropsychological assessment followed by a VTC assessment using the same test protocol within 4 months. Reliability coefficients were calculated using intraclass correlation coefficients (ICC). For each test, the proportion of clinically relevant differences in performances between assessment modalities was calculated. User experiences of patients and neuropsychologists were assessed with questionnaires (User Satisfaction and Ease of use [USE] questionnaire and System Usability Scale [SUS]). Neuropsychologists also participated in a focus group.</p><p><strong>Results: </strong>ICC values were moderate to excellent (0.63-0.93) for all test measures in the total sample. On all tests, most patients did not show clinically relevant performance differences between modalities. Patients and neuropsychologists reported overall positive VTC system usability, although neuropsychologists indicated in the focus group that patients without cognitive impairment required less training for the system and were more independent.</p><p><strong>Conclusion: </strong>VTC assessment showed adequate to excellent test-retest reliability for a broad range of neuropsychological tests commonly used in practice. Assessment through VTC may be a user friendly method in the memory clinic, especially to monitor individuals at risk for future cognitive decline.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julie Remaud, Jérémy Besnard, Sébastien Barbarot, Arnaud Roy
{"title":"Social cognition in adults with neurofibromatosis type 1.","authors":"Julie Remaud, Jérémy Besnard, Sébastien Barbarot, Arnaud Roy","doi":"10.1017/S1355617724000560","DOIUrl":"https://doi.org/10.1017/S1355617724000560","url":null,"abstract":"<p><strong>Objective: </strong>Adult patients with the genetic disease neurofibromatosis type 1 (NF1) frequently report social difficulties. To date, however, only two studies have explored whether these difficulties are caused by social cognition deficits, and these yielded contradictory data. The aim of the present study was to exhaustively assess social cognition abilities (emotion, theory of mind, moral reasoning, and social information processing) in adults with NF1, compared with a control group, and to explore links between social cognition and disease characteristics (mode of inheritance, severity, and visibility).</p><p><strong>Method: </strong>We administered a social cognition battery to 20 adults with NF1 (mean age = 26.5 years, <i>SD</i> = 7.4) and 20 healthy adults matched for sociodemographic variables.</p><p><strong>Results: </strong>Patients scored significantly lower than controls on emotion, theory of mind, moral reasoning, and social information processing tasks. No effects of disease characteristics were found.</p><p><strong>Conclusions: </strong>These results appear to confirm that adults with NF1 have a social cognition weaknesses that could explain, at least in part, their social difficulties, although social abilities are not all impaired to the same extent. Regarding the impact of the disease characteristics, the patient sample seemed slightly insufficient for the power analyses performed. Thus, this exploratory study should form the basis of further research, with the objective of replicating these results with larger and more appropriately matched samples.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Wechsler Adult Intelligence Scale - IV México versus U.S. versions in the assessment of Mexican Americans.","authors":"Gabriela Ontiveros, Philip Gerard Gasquoine","doi":"10.1017/S135561772400050X","DOIUrl":"https://doi.org/10.1017/S135561772400050X","url":null,"abstract":"<p><strong>Objective: </strong>To delineate score differences between the Wechsler Adult Intelligence Scale-IV (WAIS-IV) and the WAIS-IV México in the assessment of balanced bilingual Mexican Americans and to determine the efficacy of five hold measures in predicting summary scores in each version.</p><p><strong>Methods: </strong>Hold measures were WAIS-IV Information, Vocabulary, and Matrix Reasoning subtests, picture vocabulary, and the Test of Premorbid Function (English)/Word Accentuation Test (Spanish). Using a repeated measures design, 60 neurologically intact participants were tested in a counterbalanced order, with WAIS-IV version as the repeated measure (mean intertest interval = 5.68 days). To minimize practice effects, the five visual-perceptual subtests, which contain the same items in each version, were administered only once during the initial session.</p><p><strong>Results: </strong>All mean WAIS-IV México index/subtest scores were significantly higher than the U.S. equivalents (Full-Scale IQ by about .5 <i>SD</i>). Unexpectedly, most (83%) participants educated in the US to at least a high school level had numerically equal or higher scores on the U.S. version. Means on WAIS-IV language format indices/subtests were lower than those of visual-perceptual format indices/subtests within both versions (excepting Processing Speed Index/subtests in the U.S. version). All hold measures significantly predicted WAIS-IV summary scores for the U.S. version. Similarly for the México version, except for the Word Accentuation Test.</p><p><strong>Conclusions: </strong>When evaluating a balanced bilingual Mexican American, opting for the WAIS-IV México version will yield higher scores across the Full-Scale IQ, indices, and all core subtests unless the patient was educated in the US to at least a high school level.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan J Torres, Sylvia Mackala, Sharon Ahn, Erin E Michalak, Trisha Chakrabarty, Raymond W Lam, Kamyar Keramatian, Lakshmi N Yatham
{"title":"Relationship between subjective cognitive functioning and fluid and crystallized cognitive abilities in bipolar disorder.","authors":"Ivan J Torres, Sylvia Mackala, Sharon Ahn, Erin E Michalak, Trisha Chakrabarty, Raymond W Lam, Kamyar Keramatian, Lakshmi N Yatham","doi":"10.1017/S1355617724000559","DOIUrl":"https://doi.org/10.1017/S1355617724000559","url":null,"abstract":"<p><strong>Objective: </strong>People with bipolar disorder (BD) often show inaccurate subjective ratings of their objective cognitive function. However, it is unclear what information individuals use to formulate their subjective ratings. This study evaluated whether people with BD are likely using information about their crystallized cognitive abilities (which involve an accumulated store of verbal knowledge and skills and are typically preserved in BD) or their fluid cognitive abilities (which involve the capacity for new learning and information processing in novel situations and are typically impaired in BD) to formulate their subjective cognitive ratings.</p><p><strong>Method: </strong>Eighty participants diagnosed with BD and 55 control volunteers were administered cognitive tests assessing crystallized and fluid cognitive abilities. Subjective cognitive functioning was assessed with the Cognitive Failures Questionnaire (CFQ), daily functioning was rated using the Multidimensional Scale of Independent Functioning (MSIF) and the Global Assessment of Functioning Scale (GAF), and quality of life was assessed with the Quality of Life in Bipolar Disorder scale (QoL.BD).</p><p><strong>Results: </strong>The BD group exhibited considerably elevated subjective cognitive complaints relative to controls. Among participants with BD, CFQ scores were associated with fluid cognitive abilities including measures of memory and executive function, but not to crystallized abilities. After controlling for objective cognition and depression, higher cognitive complaints predicted poorer psychosocial outcomes.</p><p><strong>Conclusions: </strong>Cognitive self-reports in BD may represent a metacognitive difficulty whereby cognitive self-appraisals are distorted by a person's focus on their cognitive weaknesses rather than strengths. Moreover, negative cognitive self-assessments are associated with poorer daily functioning and diminished quality of life.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sam Humphrey, Kerryn E Pike, Brian Long, Henry Ma, Robert Bourke, Bradley J Wright, Dana Wong
{"title":"Neuropsychological outcomes following endovascular clot retrieval and intravenous thrombolysis in ischemic stroke.","authors":"Sam Humphrey, Kerryn E Pike, Brian Long, Henry Ma, Robert Bourke, Bradley J Wright, Dana Wong","doi":"10.1017/S1355617724000535","DOIUrl":"https://doi.org/10.1017/S1355617724000535","url":null,"abstract":"<p><strong>Objectives: </strong>Cognitive impairment, anxiety, depression, fatigue, and dependence in instrumental activities of daily living (ADL) are common after stroke; however, little is known about how these outcomes may differ following treatment with endovascular clot retrieval (ECR), intravenous tissue plasminogen activator (t-PA), or conservative management.</p><p><strong>Methods: </strong>Patients were recruited after acute treatment and invited to participate in an outcome assessment 90-120 days post-stroke. The assessment included a cognitive test battery and several questionnaires. The COVID-19 pandemic led to significant disruptions in recruitment and data collection, and the t-PA and conservative management groups were combined into a standard medical care (SMC) group.</p><p><strong>Results: </strong>Sixty-two participants were included in the study (ECR = 31, SMC = 31). Mean age was 66.5 (20-86) years, and 35 (56.5%) participants were male. Participants treated with ECR had significantly higher National Institutes of Health Stroke Scale scores at presentation and significantly lower education. After adjusting for stroke severity, premorbid intellectual ability, and age, treatment with ECR was associated with significantly better performances on measures of cognitive screening, visual working memory, and verbal learning and memory. Participants treated with ECR also experienced less fatigue and were more likely to achieve independence in basic and instrumental ADLs. Despite this, cognitive impairment and fatigue were still common among participants treated with ECR and anxiety and depression symptoms were experienced similarly by both groups.</p><p><strong>Conclusions: </strong>Cognitive impairment and fatigue were less common but still prevalent following treatment with ECR. This has important practical implications for stroke rehabilitation, and routine assessment of cognition, emotion, and fatigue is recommended for all stroke survivors regardless of stroke treatment and functional outcome.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adherence to high-frequency ecological momentary assessment in persons with moderate-to-severe traumatic brain injury.","authors":"Amanda R Rabinowitz, Tessa Hart","doi":"10.1017/S1355617724000493","DOIUrl":"https://doi.org/10.1017/S1355617724000493","url":null,"abstract":"<p><strong>Objective: </strong>Ecological momentary assessment (EMA) involves repeated collection of real-time self-report data, often multiple times per day, nearly always delivered electronically by smartphone. While EMA has shown promise for researching internal states, behaviors, and experiences in multiple populations, concerns remain regarding its feasibility in samples with cognitive impairments, like those associated with chronic moderate-to-severe traumatic brain injury (TBI).</p><p><strong>Methods: </strong>This study examines adherence to a 7-week high-frequency (5x daily) EMA protocol in individuals with moderate-to-severe TBI, considering changes in response rate over time, as well as individual participant characteristics (memory function, education, injury severity, and age).</p><p><strong>Results: </strong>In the sample of 39 participants, the average overall response rate was 65% (range: 5%-100%). Linear mixed-effects modeling revealed a small but statistically significant linear decay in response rate over 7 weeks of participation. Individual trajectories were variable, as evidenced by the significant effect of random slope. A better response rate was positively associated with greater educational attainment and better episodic memory function (statistical trend), whereas the effects of age and injury severity were not significant.</p><p><strong>Conclusions: </strong>These findings shed light on the potential of EMA in TBI studies but underscore the need for tailored strategies to address individual barriers to adherence.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karen Blackmon, Roberta Evans, Lauren Mohammed, Kemi S Burgen, Erin Ingraham, Bianca Punch, Rashida Isaac, Toni Murray, Jesma Noel, Cora Belmar-Roberts, Randall Waechter, Barbara Landon
{"title":"The Grenada Learning and Memory Scale: Psychometric features and normative data in Caribbean preschool children.","authors":"Karen Blackmon, Roberta Evans, Lauren Mohammed, Kemi S Burgen, Erin Ingraham, Bianca Punch, Rashida Isaac, Toni Murray, Jesma Noel, Cora Belmar-Roberts, Randall Waechter, Barbara Landon","doi":"10.1017/S1355617724000481","DOIUrl":"https://doi.org/10.1017/S1355617724000481","url":null,"abstract":"<p><strong>Objective: </strong>Neuropsychological assessment of preschool children is essential for early detection of delays and referral for intervention prior to school entry. This is especially pertinent in low- and middle-income countries (LMICs), which are disproportionately impacted by micronutrient deficiencies and teratogenic exposures. The Grenada Learning and Memory Scale (GLAMS) was created for use in limited resource settings and includes a shopping list and face-name association test. Here, we present psychometric and normative data for the GLAMS in a Grenadian preschool sample.</p><p><strong>Methods: </strong>Typically developing children between 36 and 72 months of age, primarily English speaking, were recruited from public preschools in Grenada. Trained Early Childhood Assessors administered the GLAMS and NEPSY-II in schools, homes, and clinics. GLAMS score distributions, reliability, and convergent/divergent validity against NEPSY-II were evaluated.</p><p><strong>Results: </strong>The sample consisted of 400 children (190 males, 210 females). GLAMS internal consistency, inter-rater agreement, and test-retest reliability were acceptable. Principal components analysis revealed two latent factors, aligned with expected verbal/visual memory constructs. A female advantage was observed in verbal memory. Moderate age effects were observed on list learning/recall and small age effects on face-name learning/recall. All GLAMS subtests were correlated with NEPSY-II Sentence Repetition, supporting convergent validity with a measure of verbal working memory.</p><p><strong>Conclusions: </strong>The GLAMS is a psychometrically sound measure of learning and memory in Grenadian preschool children. Further adaptation and scale-up to global LMICs are recommended.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun-Hsuan Kuo, Jinn-Rung Kuo, Tee-Tau Eric Nyam, Che-Chuan Wang, Bei-Yi Su
{"title":"Beyond brain injury: Examining the neuropsychological and psychosocial sequelae of post-traumatic epilepsy.","authors":"Yun-Hsuan Kuo, Jinn-Rung Kuo, Tee-Tau Eric Nyam, Che-Chuan Wang, Bei-Yi Su","doi":"10.1017/S1355617724000456","DOIUrl":"https://doi.org/10.1017/S1355617724000456","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates neuropsychological and psychosocial outcomes in patients with traumatic brain injury (TBI) and post-traumatic epilepsy (PTE) compared to a healthy control group.</p><p><strong>Method: </strong>Utilizing a quasi-experimental cross-sectional design, the research involved patients with TBI and PTE referred from a Taiwanese medical center. An age- and education-matched control group of healthy adults without traumatic injuries was also recruited. The study involved analyzing retrospective medical records and applying a comprehensive suite of neuropsychological tests and psychosocial questionnaires.</p><p><strong>Results: </strong>Executive function measures revealed significantly reduced performance in both the TBI and PTE groups compared to controls. Specifically, the MoCA scores were lowest in the PTE group, followed by the TBI group, and highest in the controls. Measures of subjective symptomatology showed comparably elevated levels in both the TBI and PTE groups relative to controls.</p><p><strong>Conclusion: </strong>The research suggests that PTE may intensify the difficulties faced by individuals with TBI, but its impact on overall recovery might not be significant, considering the trajectory of the brain injury itself. Notably, the MoCA results indicate that cognitive deficits are more pronounced in PTE patients compared to those with TBI, underscoring the necessity for targeted neuropsychological assessments. Further investigation is essential to explore PTE's broader neuropsychological and psychosocial impacts. These findings advocate for tailored care strategies that address both neuropsychological and psychosocial needs, ensuring comprehensive management of TBI and PTE.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louisa I Thompson, Alyssa N De Vito, Zachary J Kunicki, Sheina Emrani, Jennifer Strenger, Caroline Nester, Karra D Harrington, Nelson Roque, Masood Manoocheri, Stephen Salloway, Stephen Correia, Richard N Jones, Martin J Sliwinski
{"title":"Psychometric and adherence considerations for high-frequency, smartphone-based cognitive screening protocols in older adults.","authors":"Louisa I Thompson, Alyssa N De Vito, Zachary J Kunicki, Sheina Emrani, Jennifer Strenger, Caroline Nester, Karra D Harrington, Nelson Roque, Masood Manoocheri, Stephen Salloway, Stephen Correia, Richard N Jones, Martin J Sliwinski","doi":"10.1017/S1355617724000328","DOIUrl":"https://doi.org/10.1017/S1355617724000328","url":null,"abstract":"<p><strong>Objective: </strong>The psychometric rigor of unsupervised, smartphone-based assessments and factors that impact remote protocol engagement is critical to evaluate prior to the use of such methods in clinical contexts. We evaluated the validity of a high-frequency, smartphone-based cognitive assessment protocol, including examining convergence and divergence with standard cognitive tests, and investigating factors that may impact adherence and performance (i.e., time of day and anticipated receipt of feedback vs. no feedback).</p><p><strong>Methods: </strong>Cognitively unimpaired participants (N = 120, M<sub>age</sub> = 68.8, 68.3% female, 87% White, M<sub>education</sub> = 16.5 years) completed 8 consecutive days of the Mobile Monitoring of Cognitive Change (M2C2), a mobile app-based testing platform, with brief morning, afternoon, and evening sessions. Tasks included measures of working memory, processing speed, and episodic memory. Traditional neuropsychological assessments included measures from the Preclinical Alzheimer's Cognitive Composite battery.</p><p><strong>Results: </strong>Findings showed overall high compliance (89.3%) across M2C2 sessions. Average compliance by time of day ranged from 90.2% for morning sessions, to 77.9% for afternoon sessions, and 84.4% for evening sessions. There was evidence of faster reaction time and among participants who expected to receive performance feedback. We observed excellent convergent and divergent validity in our comparison of M2C2 tasks and traditional neuropsychological assessments.</p><p><strong>Conclusions: </strong>This study supports the validity and reliability of self-administered, high-frequency cognitive assessment via smartphones in older adults. Insights into factors affecting adherence, performance, and protocol implementation are discussed.</p>","PeriodicalId":49995,"journal":{"name":"Journal of the International Neuropsychological Society","volume":null,"pages":null},"PeriodicalIF":2.6,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}