Journal of Thoracic and Cardiovascular Surgery最新文献

{"title":"Surgery for lung cancer: Time waits for no one.","authors":"Xuhua Huang, Linhai Zhu, Jian Hu","doi":"10.1016/j.jtcvs.2025.01.003","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.003","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who can benefit from operating room extubation?","authors":"Marcin P Szczechowicz, Gábor Szabó, Gábor Veres, Angelo M Dell'Aquila","doi":"10.1016/j.jtcvs.2025.01.004","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.004","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrathoracic versus cervical anastomosis in esophagectomy: A further discussion.","authors":"Linghan Tian, Chao Ming, Ming Jiang, Jie Zhao","doi":"10.1016/j.jtcvs.2025.01.005","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.005","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical and Long-term Outcomes of Combined Organ Resection for Esophageal Cancer Invading Adjacent Organs: Experience of 90 Consecutive Cases.","authors":"Tomoki Makino, Makoto Yamasaki, Shigeto Nakai, Kota Momose, Kotaro Yamashita, Koji Tanaka, Kazuo Shimamura, Masaaki Motoori, Yukinori Kurokawa, Yutaka Kimura, Kiyokazu Nakajima, Shigeru Miyagawa, Hidetoshi Eguchi, Yuichiro Doki","doi":"10.1016/j.jtcvs.2025.01.017","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.017","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the feasibility of and long-term survival with combined organ resection for esophageal cancer (EC).</p><p><strong>Background: </strong>The optimal treatment strategy for EC that is invading adjacent organs is not established.</p><p><strong>Methods: </strong>Ninety patients with EC invading adjacent organs who underwent combined organ resection after induction treatments during 2003-2023 in our institute were eligible for the study. Short- and long-term outcomes were assessed, and survival analysis was performed to identify prognostic parameters in this cohort.</p><p><strong>Results: </strong>Most had primary tumors (78.9% vs. 21.1% with recurrent disease). The resected organs were the trachea/bronchus in 75.6%, large vessels in 24.4%, and both in 5.6%. All but one patient underwent chemotherapy or chemoradiotherapy as prior induction treatment and had R0 resection. The overall complication rate (Clavien-Dindo ≥ grade II) was 54.4%, and in-hospital mortality was 2.2% (30- and 90-day mortality: 0% and 2.2%, respectively). Of the deaths, 47 (87.0%) were attributed to EC and 7 (13.0%) to other causes. Median disease-free survival was 6.5 months, and overall survival (OS) was 18.9 months. The 2-year OS values were 47.2% with trachea/bronchus resection, 38.4% with large vessel involvement, and 37.5% if both were involved. Univariate analysis of OS demonstrated significant associations of operation time (HR=2.11, P=0.0080), blood loss (HR=2.85, P=0.0003), all-layer tracheal resection (HR=3.51, P=0.0045), ypT (HR=2.04, P=0.022), and pathological response (HR=2.77, P=0.0089).</p><p><strong>Conclusion: </strong>If patient selection is highly selected, combined organ resection may be a feasible and promising option as a part of the multidisciplinary treatment for EC invading an adjacent organ.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mixed reality for preoperative planning and intraoperative assistance of surgical correction of complex congenital heart defects.","authors":"Matteo Ponzoni, Francesco Bertelli, Shi-Joon Yoo, Brandon Peel, Hannah Seatle, Osami Honjo, Christoph Haller, David J Barron, Mike Seed, Christopher Z Lam, Aamir Jeewa, Encarnacion Gutierrez Carretero, Antonio Ordonez, Israel Valverde","doi":"10.1016/j.jtcvs.2024.12.034","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.12.034","url":null,"abstract":"<p><strong>Objectives: </strong>Mixed reality (MixR) is an innovative visualization tool that presents virtual elements in a real-world environment, enabling real-time interaction between the user and the combined digital/physical reality. We aimed to explore the feasibility of MixR in enhancing preoperative planning and intraoperative guidance for the correction of various complex congenital heart defects (CHDs).</p><p><strong>Methods: </strong>Patients underwent cardiac computed tomography or cardiac magnetic resonance and segmentation of digital imaging and communications in medicine (DICOM) images was performed. Three-dimensional models were then uploaded into a MixR headset (Microsoft HoloLens 2), displayed as holograms, and used for preoperative navigation of cardiac anatomy and intraoperative assistance of surgical steps.</p><p><strong>Results: </strong>We adopted MixR in 5 different clinical scenarios: minimally-invasive partial anomalous pulmonary venous connection repair of 5 anomalous veins; intra-extracardiac Fontan completion in right atrial isomerism and dextrocardia; arterial switch operation for transposition of the great arteries with abnormal coronary pattern in situs inversus; complete unifocalization of major aortopulmonary collateral arteries; total artificial heart implantation for failing Fontan. Preoperative MixR allowed a comprehensive understanding of complex anatomical relationships and spatial mapping, using immersive 3D navigation. As a result, the surgeon was able to simulate the surgical approach and plan the best surgical strategy. Intraoperatively, MixR provided a real-time virtual map by overlaying holograms onto the patient's anatomy.</p><p><strong>Conclusions: </strong>MixR represents a promising tool for preoperative planning and 3D visualization in complex CHDs, however, its systematic adoption in the intraoperative setting requires further implementation of current hardware technology and software versatility.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Treatment of Atrial Fibrillation in Coronary Artery Bypass Grafting.","authors":"Sarah Nisivaco, Taras Lysyy, Jane Kruse, James L Cox, S Chris Malaisrie","doi":"10.1016/j.jtcvs.2025.01.014","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.014","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Circulatory Arrest Recovery Ammonia Problem (CARAP) Hypothesis: a ¹H-MRS study of brain metabolism during neonatal cardiopulmonary bypass surgery.","authors":"Daniel Spielman, Meng Gu, Hunter Liu, Shie-Chau Liu, Ralph Hurd, Kirk Riemer, Kenichi Okamura, Masafumi Shibata, Paul Shuttleworth, Zachary Kleiman, Karla Epperson, Kevin Epperson, Frank Hanley","doi":"10.1016/j.jtcvs.2025.01.016","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.016","url":null,"abstract":"<p><strong>Objective: </strong>Congenital heart disease affects 1% of US births, with many babies requiring major cardiothoracic surgery under cardiopulmonary bypass (CPB), exposing the more critical patients to neurodevelopmental impairment. Optimal surgical parameters to minimize neuronal injury are unknown. We used ¹H MRS and blood ammonia assays in a neonatal pig model of CPB to compare two approaches, complete circulatory arrest (CA) versus antegrade cerebral perfusion (ACP).</p><p><strong>Methods: </strong>Two-week old piglets (N=17) were put on a CPB pump and placed in a 3T MRI to study brain metabolism during CPB. Dynamic single-voxel ¹H MRS brain data were acquired while animals underwent one of four CPB protocols: ∼50 min CA at 18ºC and 28ºC or ACP at 18ºC and 28ºC, followed by a ∼1-hr recovery period. Based on ¹H MRS findings suggesting the presence of brain ammonia upon reperfusion, a second cohort of piglets (N=22) underwent the same CPB conditions without MRS to allow regular venous blood sampling with ammonia assays.</p><p><strong>Results: </strong>All animals showed a transitory temperature-dependent rise in blood ammonia (p < .001) immediately following restart of whole-body perfusion . In contrast, metabolic processing of brain ammonia, as detected by an increased ¹H MRS glutamine/glutamate ratio, was also temperature dependent (p =.002) but only significantly observed in the CA studies (p =.009).</p><p><strong>Conclusions: </strong>Serial ¹H-MRS and blood ammonia assays in this preclinical CPB model identified a previously unreported build-up of ammonia, hypothesized to arise from gut bacterial production, following reperfusion, that may contribute to brain injury in these pediatric surgeries.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143043063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentator Discussion: Outcomes after hospital discharge in children requiring postcardiotomy extracorporeal membrane oxygenation: A binational retrospective cohort study.","authors":"","doi":"10.1016/j.jtcvs.2024.12.022","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.12.022","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentator Discussion: Initial balloon versus surgical valvuloplasty in children with isolated congenital aortic stenosis: Impact on timing of aortic valve replacement.","authors":"","doi":"10.1016/j.jtcvs.2024.12.023","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.12.023","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing innovative AI algorithms to assess echocardiographic videos for clinical modelling.","authors":"Sidrah Laldin, Cedrique Shum-Tim, Satya Prakash, Dominique Shum-Tim","doi":"10.1016/j.jtcvs.2025.01.008","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2025.01.008","url":null,"abstract":"<p><strong>Objective(s): </strong>We conduct a comparative study that employs the use of multiple dynamic deep learning algorithms to develop predictive models with video-based echocardiographic images using sample size determination as a key variable to assess optimal performance metrics.</p><p><strong>Methods: </strong>Our study compares performance of 3D convolutional neural networks, video vision transformers, and hybrid convolutional neural networks and Long Short-Term Memory models within both supervised and semi-supervised domains using variable sample sizes.</p><p><strong>Results: </strong>For supervised learning, the ResNet3D model achieved the lowest Mean Absolute Error (MAE) and Root Mean Square Error (RMSE) across all training set sizes (200, 400, and 800-video datasets), with the best performance observed on the 800-video training set (MAE: 7.409, RMSE: 10.216). In the semi-supervised setting, both ResNet3D and ResNet+LSTM models benefited from the inclusion of unlabelled data, particularly at larger dataset sizes.</p><p><strong>Conclusions: </strong>Because semi-supervised models use both labelled and unlabelled data sets, our findings are significant in showing that performance of certain predictive models using mixtures of unlabelled and labelled data is comparable to those using only labelled data with similar sample sizes, thus obviating the need for large sample sizes of labelled data.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}