R Taylor Ripley, Prasad S Adusumilli, Adam J Bograd, Servet Bölükbas, Raphael Bueno, Robert B Cameron, Marc de Perrot, Raja M Flores, Shawn G Groth, Loïc Lang-Lazdunski, David H Harpole, Harvey I Pass, Meera Patel, Isabelle Schmitt-Opitz, Paula Antonia Ugalde Figueroa, Andrea S Wolf
{"title":"Going to MARS May Shorten Our Patient's Survival.","authors":"R Taylor Ripley, Prasad S Adusumilli, Adam J Bograd, Servet Bölükbas, Raphael Bueno, Robert B Cameron, Marc de Perrot, Raja M Flores, Shawn G Groth, Loïc Lang-Lazdunski, David H Harpole, Harvey I Pass, Meera Patel, Isabelle Schmitt-Opitz, Paula Antonia Ugalde Figueroa, Andrea S Wolf","doi":"10.1016/j.jtcvs.2024.12.006","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.12.006","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142829972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily June Zolfaghari, Oluwaseun Ayoade, Mara B Antonoff
{"title":"Barriers to fitness: Disparities in preoperative exercise access for patients with lung cancer.","authors":"Emily June Zolfaghari, Oluwaseun Ayoade, Mara B Antonoff","doi":"10.1016/j.jtcvs.2024.11.023","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.11.023","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malhar J Parikh, Louis F Chai, Manuel Garcia Russo, Anastasiia K Tompkins, Omowunmi Akinade, Cherie P Erkmen
{"title":"Dismal Adherence to Lung Cancer Screening in a Diverse Urban Population.","authors":"Malhar J Parikh, Louis F Chai, Manuel Garcia Russo, Anastasiia K Tompkins, Omowunmi Akinade, Cherie P Erkmen","doi":"10.1016/j.jtcvs.2024.12.007","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.12.007","url":null,"abstract":"<p><strong>Objectives: </strong>High-risk populations for lung cancer, including Black males and lower socioeconomic status, experience worse outcomes when treated. The mortality benefit of lung cancer screening (LCS) cannot be realized without adherence to annual screening. Our study aims to understand annual adherence to LCS in a populations traditionally experiencing health disparities, thus identifying LCS' impact on lung cancer disparities.</p><p><strong>Methods: </strong>A 10-year retrospective review of patients obtaining initial LCS (T<sub>0</sub>) at a safety-net institution was performed. Adherence was defined as LCS completed 12-15 months from prior screening (one annual=T<sub>1</sub>, two annual=T<sub>2</sub>, three annual=T<sub>3</sub>). Extended adherence was defined as LCS completed 12-18 months from prior screening. Data was stratified demographically for comparative analysis.</p><p><strong>Results: </strong>6,983 patients received LCS over 10 years. Only 8.13% adhered to T<sub>1</sub>, 3.68% at T<sub>2</sub>, and 1.35% at T<sub>3</sub>. Extending the adherence criteria showed minimal improvement: T<sub>1</sub> 10.54%, T<sub>2</sub> 4.64%, and T<sub>3</sub> 3.47%. At all intervals, males (vs. female; T<sub>1</sub>: 7.37 % vs. 9.04%, T<sub>2</sub>: 3.39% vs 4.11%, T<sub>3</sub>: 2.06% vs. 2.33%) and Hispanics (vs. Black and White; T<sub>1:</sub> 7.82% vs. 8.53% vs. 9.47%, T<sub>2</sub>: 2.12% vs. 3.42% vs. 5.12%, T<sub>3</sub>: 1.02% vs. 1.69% vs. 3.30%) had worse adherence. A small cohort presented early (1-11 months), a form of adherence not previously reported.</p><p><strong>Conclusions: </strong>In a safety-net institution with a diverse population traditionally experiencing disparities, adherence to annual LCS was low (8.13%) and declining each subsequent year, especially among male and Hispanic patients. Targeted education regarding importance of annual LCS is needed to realize the lifesaving potential of LCS.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142830658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haley I Tupper, Varada Sarovar, Kian C Banks, Julie A Schmittdiel, Diana S Hsu, Simon K Ashiku, Ashish R Patel, Lori C Sakoda, Jeffrey B Velotta
{"title":"Time to Surgery in Early-Stage Non-Small Cell Lung Cancer (NSCLC): Defining the Optimal Diagnosis-to-Resection Interval to Reduce Mortality.","authors":"Haley I Tupper, Varada Sarovar, Kian C Banks, Julie A Schmittdiel, Diana S Hsu, Simon K Ashiku, Ashish R Patel, Lori C Sakoda, Jeffrey B Velotta","doi":"10.1016/j.jtcvs.2024.11.040","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.11.040","url":null,"abstract":"<p><strong>Objective: </strong>Most patient variables that impact cancer case complexity and outcomes are not modifiable pre-operatively. However, the time from diagnosis to surgical resection is fluid. This retrospective study sought to identify the optimal time from NSCLC diagnosis to surgery to reduce mortality.</p><p><strong>Methods: </strong>We evaluated adult patients with early-stage NSCLC who underwent upfront surgical resection between 2009-2019 using institutional data. Diagnosis date was uniformly defined as the date of computed tomography (CT) that prompted diagnostic workup. We evaluated time to surgery in 2-week intervals. Using Cox regression analysis with adjustment for key patient sociodemographic, clinical and cancer characteristics, we examined time to surgery associations with recurrent/new lung cancer and overall mortality at 1 and 5-years post-surgery.</p><p><strong>Results: </strong>Among 2567 early-stage patients, median time to surgery was 57.0 [IQR: 41.0-79.0] days. Five-year mortality was elevated for surgeries performed >8 (vs. <8) weeks (aHR [adjusted hazard ratio] 1.19 (95% CI: 1.06-1.33)) and >12 (vs. <12) weeks (aHR 1.31 (95% CI: 1.10-1.55)) post-diagnosis. One-year recurrence was also elevated for surgeries delayed >8 (vs. <8) (aHR: 1.25 (95% CI 0.98-1.60)) and >12 (vs. <12) weeks (aHR 1.62 (95% CI: 1.12-2.36)).</p><p><strong>Conclusions: </strong>Although NSCLC aggressiveness varies, quality metrics for time to surgery are needed to optimize outcomes. This will be increasingly important as more early-stage, resectable NSCLC is identified. Our results suggest that performing surgery within 8 weeks of CT-based clinical diagnosis may be an important heath system target for early-stage NSCLC patients.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: The next horizon in the surgical management of single ventricle patients.","authors":"David S Winlaw","doi":"10.1016/j.jtcvs.2024.10.061","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.10.061","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: Reoperative aortic root replacement - further evidence of feasibility….. and expertise still matters.","authors":"Afshin Ehsan","doi":"10.1016/j.jtcvs.2024.10.060","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.10.060","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayhan Muduroglu, Mustafa Selçuk Atasoy, Serdar Badem, Ahmet Yuksel, Yusuf Velioglu
{"title":"Routine one-third arch replacement in type 1 acute aortic dissection surgery.","authors":"Ayhan Muduroglu, Mustafa Selçuk Atasoy, Serdar Badem, Ahmet Yuksel, Yusuf Velioglu","doi":"10.1016/j.jtcvs.2024.11.011","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.11.011","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Doug A Gouchoe, Divyaam Satija, Ervin Y Cui, Jacob N Schroder, Carmelo A Milano, Muath Bishawi, Ammu V Alvarez, Kukbin Choi, Matthew C Henn, Brent C Lampert, Nahush A Mokadam, Bryan A Whitson, Asvin M Ganapathi
{"title":"Rise of the Machines - Normothermic Regional Perfusion Use in Heart Transplantation in the United States.","authors":"Doug A Gouchoe, Divyaam Satija, Ervin Y Cui, Jacob N Schroder, Carmelo A Milano, Muath Bishawi, Ammu V Alvarez, Kukbin Choi, Matthew C Henn, Brent C Lampert, Nahush A Mokadam, Bryan A Whitson, Asvin M Ganapathi","doi":"10.1016/j.jtcvs.2024.12.001","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.12.001","url":null,"abstract":"<p><strong>Objective: </strong>Recently, normothermic regional perfusion (NRP) and direct procurement and perfusion (DPP) have allowed for heart transplantation following donation after circulatory death (DCD). This study aimed to characterize utilization and variation of NRP and DPP in the United States.</p><p><strong>Methods: </strong>Heart transplants from 12/1/19-3/31/24 were identified from the United Network for Organ Sharing Database. DPP and NRP procurements were classified based on previously published methods. The groups were compared, and survival was assessed using Kaplan-Meier methods. Geographic and center variability was categorized using encrypted data.</p><p><strong>Results: </strong>There were 595 NRP transplants and 625 DPP transplants. Distance traveled and out of body time were significantly less for the NRP group (p<0.01 for both). There were no significant differences in post-operative dialysis, stroke or 1-year survival between groups, however post-operative pacemaker placement was higher with NRP (p<0.05). From 2019 to 2024, 54/61 centers (88.5%) used NRP, 50/61 centers (82%) used DPP, and 43/61 centers (70.5%) used both procurement techniques, with NRP currently being the most popular DCD procurement technique. Geographically, recipients from regions 2, 5 and 8 used NRP with greatest frequency, while those in regions 1, 3 and 10 used DPP with greatest frequency.</p><p><strong>Conclusion: </strong>NRP use is rising within the United States, with tremendous growth since its inception a few years ago. Significant variation still exists regarding utilization of NRP and DPP and further determination of the impact of each procurement and preservation strategy on transplantation outcomes is necessary.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentator Discussion: Early outcomes in heart transplantation using donation after circulatory death donors in patients bridged with durable left ventricular assist devices.","authors":"","doi":"10.1016/j.jtcvs.2024.11.001","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.11.001","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurélien Bobiet, Jamil Hajj-Chahine, Christophe Jayle, Pierre Corbi
{"title":"Don't forget the frozen elephant trunk.","authors":"Aurélien Bobiet, Jamil Hajj-Chahine, Christophe Jayle, Pierre Corbi","doi":"10.1016/j.jtcvs.2024.11.010","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.11.010","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142803048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}