{"title":"Commentary: Is it really that hard?","authors":"Brendon M. Stiles MD, Marc Vimolratana MD","doi":"10.1016/j.jtcvs.2025.05.007","DOIUrl":"10.1016/j.jtcvs.2025.05.007","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 924-925"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: Cum grano salis","authors":"Gaetano Rocco MD","doi":"10.1016/j.jtcvs.2025.06.010","DOIUrl":"10.1016/j.jtcvs.2025.06.010","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 943-944"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144327584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Congenital Articles in AATS Journals","authors":"","doi":"10.1016/S0022-5223(25)00731-7","DOIUrl":"10.1016/S0022-5223(25)00731-7","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Page e98"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mario O'Connor MD , Maria E. Hoyos MD , Lee M. Fuentes MD , Hugo R. Martinez MD , Charles D. Fraser Jr. MD , Andrew Well MD
{"title":"Surgical trends and outcomes of neonatal Ebstein's anomaly: Multi-institutional study","authors":"Mario O'Connor MD , Maria E. Hoyos MD , Lee M. Fuentes MD , Hugo R. Martinez MD , Charles D. Fraser Jr. MD , Andrew Well MD","doi":"10.1016/j.jtcvs.2025.05.018","DOIUrl":"10.1016/j.jtcvs.2025.05.018","url":null,"abstract":"<div><h3>Objective</h3><div>Ebstein's anomaly is a rare condition that can be diagnosed at any age. Symptomatic neonatal Ebstein's anomaly represents a challenging clinical entity with high morbidity and mortality. This study aims to describe treatment modalities and outcomes in neonatal Ebstein's anomaly.</div></div><div><h3>Methods</h3><div>We performed a review of the Pediatric<span> Health Information System from 2004 to 2023. Patients with an Ebstein's anomaly diagnosis who were admitted within the first 2 days of life and who underwent a surgical intervention during that admission were included.</span></div></div><div><h3>Results</h3><div><span>A total of 330 patients were identified; 181 (55%) were female, 155 (47%) were non-Hispanic White, the median age at the initial Ebstein's anomaly surgery was 6 (interquartile range, 3-12) days, and the median birth weight was 2.9 (interquartile range, 2.5-3.2) kg. Median follow-up time was 1.8 (interquartile range, 0.1-6.8) years. Overall, 186 patients (56%) underwent isolated aortopulmonary shunt<span><span>, 81 patients (25%) received the Starnes procedure, 58 patients (18%) received tricuspid valve repairs, and 5 patients (2%) received </span>tricuspid valve replacements. Median length of stay was 38 (interquartile range, 24-74) days with no difference across procedures (</span></span><em>P = .</em>137). In-hospital mortality was 25% (n = 81), with tricuspid valve replacements (n = 4, 80%) having the highest. In multivariable Cox analysis, Black race (hazard ratio [HR], 2.7; 95% CI, 1.43-5.19; <em>P = .</em>002) and tricuspid valve replacements (HR, 8.2; 95% CI, 2.6-25.4; <em>P</em> < .001) had increased risk of mortality; older age at surgery (HR, 0.98; 95% CI, 0.97-0.99; <em>P = .</em>044) and higher birth weight (HR, 0.99; 95% CI, 0.99-0.99; <em>P = .</em>005) had a decreased risk for mortality. Overall survival at 10 years was 71% (95% CI, 66.0-76.3), and freedom from any cardiac reintervention at 10 years was 18% (95% CI, 12.7-25.8).</div></div><div><h3>Conclusions</h3><div>In a large multicenter dataset, surgery for neonatal Ebstein's anomaly is associated with significant mortality. Older age at surgery and higher birth weight are associated with decreased mortality. The initial approach does not dictate the need for a single ventricle pathway. These data can help counsel patients/families and help guide surveillance protocols and long-term management in this population.</div></div>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 1161-1169.e4"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical innovation: Does it truly improve long-term survival?","authors":"Xin Yan NP , Xian Gong MD , Zhang Yang MD","doi":"10.1016/j.jtcvs.2025.04.006","DOIUrl":"10.1016/j.jtcvs.2025.04.006","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Page e84"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Berk Aykut MD , Hiba Ghandour MD , Michael Mensah-Mamfo BS , Smith M. Ngeve BA , Tatum Baldwin BS , Cathlyn K. Medina BA , John A. Kucera MD , Seth E. Wolf MD , Tariq M. Omer MS , John K. Cook BS , Sydney E. Jeffs BS , Lauren E. Parker BS , Amy Evans MS , Stephen G. Miller MD , Joseph W. Turek MD, PhD, MBA , Douglas M. Overbey MD, MPH
{"title":"Partial heart transplant valves demonstrate growth in piglets despite prolonged cold storage","authors":"Berk Aykut MD , Hiba Ghandour MD , Michael Mensah-Mamfo BS , Smith M. Ngeve BA , Tatum Baldwin BS , Cathlyn K. Medina BA , John A. Kucera MD , Seth E. Wolf MD , Tariq M. Omer MS , John K. Cook BS , Sydney E. Jeffs BS , Lauren E. Parker BS , Amy Evans MS , Stephen G. Miller MD , Joseph W. Turek MD, PhD, MBA , Douglas M. Overbey MD, MPH","doi":"10.1016/j.jtcvs.2025.03.018","DOIUrl":"10.1016/j.jtcvs.2025.03.018","url":null,"abstract":"<div><h3>Background</h3><div><span>Traditional heart valve replacement options lack growth potential, limiting their long-term effectiveness in pediatric patients. Partial heart transplantation is an emerging approach that offers growth-capable valves by transplanting only the valve-containing segment of the heart. We report on the effects of extended </span>cold storage on the viability and growth potential of partial heart transplantation grafts.</div></div><div><h3>Methods</h3><div><span><span>Pulmonary and aortic conduits were harvested from piglets and human donors and stored at 4°C in cold-storage solution, with some samples supplemented with apoptosis inhibitors, </span>membrane stabilizers, and antibiotics to optimize </span>cellular viability<span>. Viability was assessed in vitro over 7 days using the MTS assay<span>. A piglet model of pulmonary valve replacement was used to assess in vivo growth potential after 1 week of cold storage.</span></span></div></div><div><h3>Results</h3><div><span><span>In vitro analysis showed a gradual decline in metabolic activity over 7 days, with approximately 50% viability retained in both porcine and human valves. Supplementation with apoptosis inhibitors and </span>membrane stabilizers did not significantly enhance viability. In vivo, transplanted conduits demonstrated robust leaflet and annular growth without significant </span>stenosis or regurgitation, confirming the maintenance of growth potential despite reduced viability.</div></div><div><h3>Conclusions</h3><div>Partial heart transplantation grafts can be preserved in cold storage for up to 1 week without significantly compromising in vivo growth potential. These findings support the feasibility of partial heart transplantation as a viable growth-capable valve replacement option for children and suggest that optimized cold storage protocols could facilitate broader access to this technique.</div></div>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 1119-1124.e1"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuan Xue MD , Yeting Lou MD , Shipan Wang MD , Yazhe Zhang MD , Xiaomeng Wang MD , Xuehuan Zhang MD , Yue Shi MD , Youjin Li MD , Haiping Yang MD , Hongli Li MD , Gang Liu MD , Minjia Zhu MD , Jian Huang MD , Qingwu Zhao MD , Jihong Liu MD , Haibo Wu MD , Duanduan Chen PhD , Wenjian Jiang MD , Hongjia Zhang MD , Haiyang Li MD
{"title":"Optimal circulatory arrest temperature for total aortic arch replacement: Outcomes of neurological complications","authors":"Yuan Xue MD , Yeting Lou MD , Shipan Wang MD , Yazhe Zhang MD , Xiaomeng Wang MD , Xuehuan Zhang MD , Yue Shi MD , Youjin Li MD , Haiping Yang MD , Hongli Li MD , Gang Liu MD , Minjia Zhu MD , Jian Huang MD , Qingwu Zhao MD , Jihong Liu MD , Haibo Wu MD , Duanduan Chen PhD , Wenjian Jiang MD , Hongjia Zhang MD , Haiyang Li MD","doi":"10.1016/j.jtcvs.2024.11.034","DOIUrl":"10.1016/j.jtcvs.2024.11.034","url":null,"abstract":"<div><h3>Objective</h3><div>The optimal hypothermic circulatory arrest temperature during total arch replacement and the impact of hypothermic circulatory arrest temperature on postoperative neurological complications are still uncertain. The aim of this study is to explore the impact of hypothermic circulatory arrest temperature on short-term postoperative outcomes, especially neurological complications, for patients who undergo total arch replacement.</div></div><div><h3>Methods</h3><div>We retrospectively analyzed data of 2351 patients who underwent total arch replacement at 1 of 7 selected aortic centers from January 2016 to June 2023. Restricted cubic splines and subgroup analyses were performed to determine the relation between temperature and outcomes under different cerebral perfusion<span> methods, cannulation strategies, diagnoses, and surgical timings.</span></div></div><div><h3>Results</h3><div>The overall in-hospital mortality was 6.2% (n = 146). The incidence of stroke, paraplegia, and total-arch composite outcome was 6.0% (n = 142), 2.8% (n = 65), and 21.0% (n = 494), respectively. The average hypothermic circulatory arrest temperature was 25.9 °C ± 1.9 °C, and the median circulatory arrest time was 23 minutes (Q1, Q3: 18, 30). Adjusted restricted cubic splines showed the lowest incidence of stroke, paraplegia, and total-arch composite outcome at temperatures of 26.6 °C, 27.4 °C, and 26.8 °C, respectively, but without statistical significance. In subgroup analysis, the unilateral antegrade cerebral perfusion group revealed a significant nonlinear relation between the hypothermic circulatory arrest temperature and the risk of stroke, and the lowest risk was at 26.5 °C. Other subgroup analyses did not reveal a significant nonlinear relation between temperature and outcomes.</div></div><div><h3>Conclusions</h3><div>For patients undergoing total arch replacement with unilateral antegrade cerebral perfusion, cooling to a temperature of 26 °C to 27 °C was associated with the lowest incidence of stroke.</div></div>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 1006-1016.e9"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical and long-term outcomes of combined organ resection for esophageal cancer invading adjacent organs: Experience of 90 consecutive cases","authors":"Tomoki Makino MD, PhD , Makoto Yamasaki MD, PhD , Shigeto Nakai MD, PhD , Kota Momose MD, PhD , Kotaro Yamashita MD, PhD , Koji Tanaka MD, PhD , Kazuo Shimamura MD, PhD , Masaaki Motoori MD, PhD , Yukinori Kurokawa MD, PhD , Yutaka Kimura MD, PhD , Kiyokazu Nakajima MD, PhD , Shigeru Miyagawa MD, PhD , Hidetoshi Eguchi MD, PhD , Yuichiro Doki MD, PhD","doi":"10.1016/j.jtcvs.2025.01.017","DOIUrl":"10.1016/j.jtcvs.2025.01.017","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the feasibility of and long-term survival with combined organ resection for esophageal cancer (EC). The optimal treatment strategy for EC that is invading adjacent organs is not established.</div></div><div><h3>Methods</h3><div>Ninety patients with EC invading adjacent organs who underwent combined organ resection after induction treatments during the time period 2003-2023 in our institute were eligible for the study. Short- and long-term outcomes were assessed, and survival analysis was performed to identify prognostic parameters in this cohort.</div></div><div><h3>Results</h3><div>Most patients had primary tumors (78.9% vs 21.1% with recurrent disease). The resected organs were the trachea/bronchus in 75.6%, large vessels in 24.4%, and both in 5.6%. All but 1 patient underwent chemotherapy or chemoradiotherapy as prior induction treatment, and had R0 resection. The overall complication rate (Clavien-Dindo grade II or greater) was 54.4%, and in-hospital mortality was 2.2% (30- and 90-day mortality: 0% and 2.2%, respectively). Of the deaths, 47 (87.0%) were attributed to EC and 7 (13.0%) to other causes. Median disease-free survival was 6.5 months, and overall survival (OS) was 18.9 months. The 2-year OS values were 47.2% with trachea/bronchus resection, 38.4% with large-vessel involvement, and 37.5% if both were involved. Univariate analysis of OS demonstrated significant associations of operation time (hazard ratio [HR], 2.11; <em>P</em> = .0080), blood loss (HR, 2.85; <em>P</em> = .0003), all-layer tracheal resection (HR, 3.51; <em>P</em> = .0045), ypT (HR, 2.04; <em>P</em> = .022), and pathologic response (HR, 2.77; <em>P</em> = .0089).</div></div><div><h3>Conclusions</h3><div>If patient selection is highly selected, combined organ resection may be a feasible and promising option as a part of the multidisciplinary treatment for EC invading an adjacent organ.</div></div>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 957-968"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J'undra N. Pegues MD, MS , Chiang-Hua Chang PhD , Raed M. Alnajjar MD , Shiwei Zhou MD , Robert B. Hawkins MD, MSc , Alphonse DeLucia III MD , Charles F. Schwartz MD , Michael P. Thompson PhD , Thomas M. Braun PhD , Geoffrey D. Barnes MD, MSc , Eric N. Hammond PhD , Francis D. Pagani MD, PhD , Donald S. Likosky PhD , Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative and the Michigan Value Collaborative
{"title":"Disparities in 180-day infection rates following coronary artery bypass grafting and aortic valve replacement","authors":"J'undra N. Pegues MD, MS , Chiang-Hua Chang PhD , Raed M. Alnajjar MD , Shiwei Zhou MD , Robert B. Hawkins MD, MSc , Alphonse DeLucia III MD , Charles F. Schwartz MD , Michael P. Thompson PhD , Thomas M. Braun PhD , Geoffrey D. Barnes MD, MSc , Eric N. Hammond PhD , Francis D. Pagani MD, PhD , Donald S. Likosky PhD , Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative and the Michigan Value Collaborative","doi":"10.1016/j.jtcvs.2024.12.033","DOIUrl":"10.1016/j.jtcvs.2024.12.033","url":null,"abstract":"<div><h3>Objective</h3><div>The study objective was to compare sex and racial differences in 180-day infection rates after coronary artery bypass grafting<span> and aortic valve replacement.</span></div></div><div><h3>Methods</h3><div>A statewide Society of Thoracic Surgeons Adult Cardiac Surgery Database was linked to Medicare claims data to identify 8887 beneficiaries undergoing coronary artery bypass grafting and aortic valve replacement (surgical or transcatheter) between 2017 and 2021. The primary outcome was the incidence of 180-day infection. Secondary outcomes included 10 infection subtypes. Multivariable logistic regression<span> was used to evaluate the relationship between sex and race (Black vs non-Black) and infections. Two secondary analyses were conducted: (1) robustness of the primary analysis after excluding urinary tract infections given established sex-related differences and (2) testing a sex∗race interaction.</span></div></div><div><h3>Results</h3><div>The mean (SD) age of the cohort was 74.5 (8.9) years, with 36.9% female and 4.2% Black. The infection rate was 19.6%, although this varied by patient sex (female vs male: 23.7% vs 17.1%) and race (Black vs non-Black: 28.0% vs 19.2%), both <em>P</em> less than .0001. Differences in infection rates for female patients were driven by urinary tract infections and pneumonia for Black patients. Risk-adjusted odds of infection were 1.6-fold significantly higher among female patients but nonsignificant for Black patients. A sex∗race interaction was present, with non-Black female patients versus non-Black male patients having a 1.63 higher odds of infection.</div></div><div><h3>Conclusions</h3><div>This multicenter study identified a 1.6-fold higher odds of infection among female patients. Non-Black female versus male patients had a 63% higher odds of infection. Transdisciplinary collaborative learning interventions should be considered to address these known disparities in infection rates.</div></div>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 1098-1108.e5"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriele M. Iacona MD , Jules J. Bakhos MD, MSc , Penny L. Houghtaling MS , Aaron E. Tipton MD , Richard Ramsingh MD , Nicholas G. Smedira MD , Marc Gillinov MD , Kenneth R. McCurry MD , Edward G. Soltesz MD , Eric E. Roselli MD , Michael Z. Tong MD , Shinya G. Unai MD , Haytham J. Elgharably MD , Marijan J. Koprivanac MD , Lars G. Svensson MD, PhD , Eugene H. Blackstone MD , Faisal G. Bakaeen MD
{"title":"Multiarterial grafting in redo coronary artery bypass grafting: Type of arterial conduit and patient sex determine benefit","authors":"Gabriele M. Iacona MD , Jules J. Bakhos MD, MSc , Penny L. Houghtaling MS , Aaron E. Tipton MD , Richard Ramsingh MD , Nicholas G. Smedira MD , Marc Gillinov MD , Kenneth R. McCurry MD , Edward G. Soltesz MD , Eric E. Roselli MD , Michael Z. Tong MD , Shinya G. Unai MD , Haytham J. Elgharably MD , Marijan J. Koprivanac MD , Lars G. Svensson MD, PhD , Eugene H. Blackstone MD , Faisal G. Bakaeen MD","doi":"10.1016/j.jtcvs.2024.10.018","DOIUrl":"10.1016/j.jtcvs.2024.10.018","url":null,"abstract":"<div><h3>Objective</h3><div><span>To evaluate whether multiarterial grafting provides an incremental benefit above single arterial grafting in isolated redo </span>coronary artery bypass grafting (CABG).</div></div><div><h3>Methods</h3><div>From January 1980 to July 2020, 6559 adults underwent a total of 6693 isolated CABG reoperations<span><span>. Patients undergoing multiarterial grafting were propensity score–matched with those undergoing single arterial grafting with or without additional vein grafts, yielding 2005 well-matched pairs. Endpoints were in-hospital </span>postoperative complications, hospital mortality, and long-term mortality. The median follow-up was 10 years, with 25% of patients followed for >17 years. Multivariable multiphase hazard models and nonparametric random survival forest models for survival were used to identify patients for whom multiarterial grafting was most beneficial.</span></div></div><div><h3>Results</h3><div><span>Among propensity score–matched patients, postoperative complications in multiarterial versus single arterial grafting included any reoperation (50 [2.5%] vs 65 [3.2%]); renal failure (73 [3.6%] vs 55 [2.7%]), stroke (44 [2.2%] vs 38 [1.9%]), and deep sternal infection (36 [1.8%] vs 25 [1.2%]). In-hospital mortality was 1.7% (n = 35) in multiarterial grafting versus 2.8% (n = 56) in single arterial grafting (</span><em>P</em><span> = .03). Comparing multiarterial to single arterial grafting, overall survival<span> was 95% versus 94% at 1 year, 92% versus 88% at 3 years, 87% versus 82% at 5 years, 49% versus 42% at 15 years, and 31% versus 25% at 20 years. Better survival after multiarterial grafting was confined to males with 2 patent internal thoracic artery grafts (</span></span><em>P</em> < .0001).</div></div><div><h3>Conclusions</h3><div>Redo CABG with multiarterial grafting can be performed with lower in-hospital mortality and similar major morbidity to single arterial grafting. It is associated with better long-term survival, particularly in males when 2 internal thoracic artery grafts are used.</div></div>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":"170 4","pages":"Pages 1079-1086.e6"},"PeriodicalIF":4.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}