Journal of Thoracic and Cardiovascular Surgery最新文献

{"title":"Lung cancer invading the chest wall: The role of site of chest wall invasion.","authors":"Geraud Galvaing, Gabrielle Drevet, Jeremy Tricard, Jocelyn Gregoire, Anne-Sophie Laliberte, Serge Simard, Jean Deslauriers, François Bertin, François Tronc, Massimo Conti","doi":"10.1016/j.jtcvs.2024.08.053","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.08.053","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Multicenter Study of Operating Room Extubation and Extubation Timing following Cardiac Surgery.","authors":"Eric W Etchill, Xiaoting Wu, Diane Alejo, Clifford E Fonner, Carol Ling, Neil Worrall, Eric Lehr, Francis Pagani, Terri Haber, Patty Theurer, Jeannie Collins-Brandon, Ravi Hira, James Brevig, Erika Mallory, Charles Maynard, Donald S Likosky, Glenn J R Whitman","doi":"10.1016/j.jtcvs.2024.09.057","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.09.057","url":null,"abstract":"<p><strong>Background: </strong>In an effort to enhance recovery after cardiac surgery, intraoperative extubation has been targeted as possibly beneficial. This multi-center cohort study aimed to assess this by evaluating the outcomes of OR extubation versus extubation within six hours of intensive care unit arrival (early ICU extubation). Furthermore, we assessed time to ICU extubation and mortality and morbidity.</p><p><strong>Methods: </strong>Patients undergoing on-pump cardiac surgery across 79 hospitals between 2011-2020 were included to 1) compare outcomes among OR extubation and early ICU extubation patients, and 2) assess time to overall ICU extubation and outcomes.</p><p><strong>Results: </strong>The overall study cohort comprised 163,982 patients, including 95,982 patients [ [ OR extubation : n= 2,529 (2.6%)and early ICU extubation : n= 93,453 (97.4%)] who underwent comparison of OR with early ICU extubation. Following overlap weighting, OR extubation patients had longer OR times (5.6 vs. 5.1 hours, p < 0.0001), and higher rates of reintubation (5.2% vs 2.9%, p=0.003), prolonged ventilation (3% vs 2%, p = 0.021), reoperation for bleeding (1.5% vs 0.7%, p < 0,01), pneumonia (1.9% vs. 1.1% , p < 0.006), and greater in-hospital mortality on multivariable regression (OR 1.34, p < 0.001). OR extubation patients at centers with low OR extubation rates (< 10%, N=60) had higher mortality (odds ratio 1.6, p = 0.001). Beyond 22 hours of postoperative ICU ventilation, the risk of morbidity and mortality increased significantly .</p><p><strong>Conclusions: </strong>Few cardiac surgery patients are extubated in the OR, which is associated with no clinical benefit and with increased morbidity. Cardiac surgery programs should reconsider OR extubation following cardiopulmonary bypass. Additionally, increased intubation time, in particular > 22 hours, is associated with an increase in adverse outcomes.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The treatment of type A aortic dissection is not done once and for all: Time to focus on residual aortic dissection.","authors":"Chaojie Wang, Ge Wang, Songtao Tan, Xiaoping Fan","doi":"10.1016/j.jtcvs.2024.09.025","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.09.025","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: Is precision for septation achieved by mapping or morphology?","authors":"Robert H Anderson","doi":"10.1016/j.jtcvs.2024.10.016","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.10.016","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: With Valve-Sparing Root Replacement, a Beautiful Reconstruction is Key to Achieving a Durable Valve.","authors":"Christopher Lau","doi":"10.1016/j.jtcvs.2024.10.009","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.10.009","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Initial Cannulation Strategy Impacts Perioperative Outcomes of Acute Type A Dissection in High Volume Centers.","authors":"Malak Elbatarny, Fadi Hage, Areeba Zubair, Kevin Lachapelle, Maral Ouzounian, Jennifer Cy Chung, Francois Dagenais, Munir Boodhwani, Michael Moon, John Bozinovski, Bindu Bittira, Rony Atoui, Jonathan Hong, Michael Chu, Mark D Peterson","doi":"10.1016/j.jtcvs.2024.09.056","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.09.056","url":null,"abstract":"<p><strong>Objective: </strong>We performed an intention to treat analysis of initial cannulation strategy to assess impact on perioperative outcomes in acute type A dissection using multicenter data.</p><p><strong>Methods: </strong>All patients undergoing surgical repair of acute type A dissection from a multicenter national registry of 9 high-volume aortic centers were analyzed. Cannulation strategies included in the analysis were: Axillary, Femoral, Direct Aortic, and Innominate. Among 950 patients, we excluded those with chronic, type B dissections, and unknown initial cannulation strategy. Patients with multiple cannulation strategies were included if the sequence in which strategies were initiated was known. The final cohort consisted of 936 patients. Primary outcomes were stroke and death. Multivariable logistic regression was performed to adjust for baseline differences. P values represent Tukey's post hoc comparisons.</p><p><strong>Results: </strong>Among 936 patients, cannulation strategies in descending order included: Axillary (n=502, 53%), Femoral (n=268, 29%), Aortic (n=104, 11%), and Innominate (n=59, 6%). Of these 46 (5%) had a change in the initial cannulation strategy prior to initiating circulatory arrest, mainly for poor axillary flow or initial femoral cannulation for hemodynamic instability followed by axillary. Femoral patients were younger (61.3±13.8) than Aortic patients (66.4±12.52, p=0.01) and more likely to present with malperfusion (n=123, 45.9%) compared to Aortic, Axillary, or Innominate patients (p <0.01). Femoral patients also had the longest duration of cerebral ischemia (Femoral: 16.9±16min, Aortic: 11.5±11.8min; Axillary: 4.41±10.3min; Innominate: 2.53±6min, p<0.01 for all vs Femoral). Unadjusted risk of death, stroke, and prolonged ventilation was lowest among Axillary and Innominate patients (Figure 1A). Length of stay was also reduced among Innominate patients. Multivariable regression demonstrated Axillary [OR 0.52 (0.36-0.75), p=0.004] and Innominate [OR 0.19 (0.07-0.54), p=0.009] cannulation to be associated with significantly reduced risk of stroke (Figure 1C). A non-significant signal of reduced death in Axillary patients remained [OR 0.66 (0.45-0.96), p=0.07].</p><p><strong>Conclusions: </strong>In high volume aortic centers, an initial cannulation strategy using Axillary access is associated with reduced risk of stroke compared to Femoral. Axillary cannulation should be the preferred strategy in experienced centers if anatomy and stability allow.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early clinical outcomes in men and women undergoing proximal thoracic aortic surgery - A Swedish population-based cohort study.","authors":"Erik Braatz, Christian Olsson, Magnus Dalén, Susanne J Nielsen, Anders Jeppsson, Malin Stenman","doi":"10.1016/j.jtcvs.2024.10.008","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.10.008","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the association between female sex and 30-day mortality and postoperative complications in patients undergoing scheduled proximal thoracic aortic surgery in Sweden.</p><p><strong>Methods: </strong>In a nationwide population-based cohort study, all patients who underwent scheduled proximal thoracic aortic surgery in Sweden between 2016 and 2020 were included. The primary outcome measure was 30-day mortality. Secondary outcome measure included a combined endpoint including 30-day all-cause mortality, postoperative new onset dialysis, perioperative stroke or a prolonged need of postoperative ventilation (>48 hours). Logistic regression models and propensity score matching were used to estimate the association between female sex and primary and secondary outcomes adjusted for differences in baseline characteristics.</p><p><strong>Results: </strong>2000 patients (29% women) were analyzed. The crude 30-day all-cause mortality rate was higher in women compared to men (3.1 vs. 1.4%, p<0.001). Women were older at time of surgery (65.6 vs. 60.2 years, p<0.001), had more comorbidities and a larger maximum indexed aortic diameter (cm/m body height) at time of surgery (3.4 ± 0.56 vs. 3.0 ± 0.48, p<0.001). The adjusted risk for 30-day mortality for women compared to men was not significant (OR 1.41 CI 95% (0.70-2.83)), neither was the secondary composite endpoint (OR 0.89 CI 95% (0.62-1.27)). The propensity score matched analysis showed similar results.</p><p><strong>Conclusions: </strong>Women who underwent proximal thoracic aortic surgery had a two-fold higher unadjusted 30-day mortality risk, but the mortality risk was not significantly higher when age and comorbidities was taken into consideration.</p>","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Getting patients to adjuvant therapy after lung cancer resection: ERAS protocols and return to intended oncologic therapy.","authors":"Emily P Rabinovich, Linda W Martin","doi":"10.1016/j.jtcvs.2024.10.007","DOIUrl":"10.1016/j.jtcvs.2024.10.007","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentator Discussion: Metabolomic studies reveal an organ-protective hibernation state in donor lungs preserved at 10 °C.","authors":"","doi":"10.1016/j.jtcvs.2024.09.010","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.09.010","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentator Discussion: The cone repair allows right ventricle rehabilitation with excellent tricuspid valve function following the Starnes procedure.","authors":"","doi":"10.1016/j.jtcvs.2024.09.009","DOIUrl":"https://doi.org/10.1016/j.jtcvs.2024.09.009","url":null,"abstract":"","PeriodicalId":49975,"journal":{"name":"Journal of Thoracic and Cardiovascular Surgery","volume":null,"pages":null},"PeriodicalIF":4.9,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}