Nishita Kothary, C Matthew Hawkins, Ashley Maleki, Wafa Q Khan, Danny R Hughes
{"title":"Quantifying the Role of Interventional Radiology in Managing Patients with Hepatobiliary Cancers.","authors":"Nishita Kothary, C Matthew Hawkins, Ashley Maleki, Wafa Q Khan, Danny R Hughes","doi":"10.1016/j.jvir.2026.109090","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109090","url":null,"abstract":"<p><strong>Purpose: </strong>To quantify the role of interventional radiology (IR) in managing primary and secondary hepatobiliary cancers.</p><p><strong>Materials and methods: </strong>This retrospective study analyzed administrative data from the Centers for Medicare & Medicaid Services (CMS) using final action claims for Medicare Fee-for-Service beneficiaries from 2016 to 2021. Patients aged ≥65 years with hepatobiliary cancer were identified using International Classification of Diseases (ICD), 10th Revision, codes. Services and associated work Relative Value Units (wRVUs) provided by IR, medical oncology, radiation oncology, and surgical oncology were identified using CMS physician specialty codes. IR procedures were classified as therapeutic or supportive.</p><p><strong>Results: </strong>From 2016 to 2021, the Medicare hepatobiliary cancer cohort included 108,317-111,761 patients annually (mean age, 75 years; male, 53%). Medical oncologists treated 70% of patients, followed by interventional radiologists with 51%, radiation oncologists with 13%, and surgical oncologists with 5%. Physician service volumes and wRVU remained stable, with medical oncologists providing the largest share (69% of services and 13.7% of wRVUs), followed by interventional radiologists (2.9% and 11.7%, respectively), radiation oncologists (1.3% and 4.5%, respectively), and surgical oncologists (0.1% and 2.2%, respectively). Interventional radiologists performed 75,785 therapeutic procedures, primarily for hepatocellular carcinoma (59%). Before pandemic, IR volumes increased 57%, driven by liver ablations (+25%) and supportive services (+63%), whereas transarterial therapies declined slightly (-6%). Despite the drop in volume during the pandemic, IR saw the highest compound annual growth rate (4%) among the specialties analyzed.</p><p><strong>Conclusions: </strong>IR provides a substantial share of services for patients with hepatobiliary cancers, with rising use of therapeutic and supportive services, delivering similar wRVUs at lower costs, underscoring its growing role in cancer care.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109090"},"PeriodicalIF":3.1,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clément Marcelin, Théo Bedague, Jean David Maes, Rim Maaloum, Ludovic Minvielle, Gladys Valenzuela, Yann Le Bras, Eva Fourage
{"title":"Automated Detection of Endoleaks in CT Angiography Using a Single Deep Learning Model.","authors":"Clément Marcelin, Théo Bedague, Jean David Maes, Rim Maaloum, Ludovic Minvielle, Gladys Valenzuela, Yann Le Bras, Eva Fourage","doi":"10.1016/j.jvir.2026.109137","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109137","url":null,"abstract":"<p><strong>Aim: </strong>Detecting endoleaks on post-EVAR CT scans, especially in the presence of artifacts caused by embolic agents like Onyx, is a challenging but critical task. In this study, we propose a deep learning-based method for endoleak detection using a single object detection model.</p><p><strong>Materials and methods: </strong>A retrospective dataset comprising 249 CT scans was used, divided into training (129 scans) and test (120 scans) datasets. Ground truth annotations were obtained through 3D manual segmentation, and a preprocessing pipeline was applied. The model was trained on slices extracted from the training dataset and validated using standard metrics, including sensitivity, specificity, and AUC.</p><p><strong>Results: </strong>The model achieved high performance at both the per-slice and per-series levels. Per-slice detection yielded a ROC AUC of 96%, with a sensitivity of 91%, specificity of 93%, PPV of 55%, and NPV of 99%. At the per-series level, sensitivity and specificity were 93% and 95%, respectively. Notably, our method introduces a per-slice detection metric, which was not reported in previous studies, and uses a single model, making it computationally efficient and easy to train.</p><p><strong>Conclusion: </strong>This study demonstrates the feasibility of using deep learning for endoleak detection, offering a robust and efficient tool for clinical practice. Future work could focus on expanding the dataset and integrating additional predictive capabilities, such as endoleak classification and localization.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109137"},"PeriodicalIF":3.1,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brandon T Gaston, Varun Singh, Anil Kharga, Thomas J An, Kevin Deng, Kang Mi Lee, Ji Lei, James Markmann, Marc D Succi
{"title":"In Vitro Development and Evaluation of an Endovascular Islet Cell Stent for Type 1 Diabetes Mellitus.","authors":"Brandon T Gaston, Varun Singh, Anil Kharga, Thomas J An, Kevin Deng, Kang Mi Lee, Ji Lei, James Markmann, Marc D Succi","doi":"10.1016/j.jvir.2026.109140","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109140","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the in vitro development and benchtop evaluation of the IsletStent, an endovascular biologic stent-graft incorporating expanded polytetrafluoroethylene (ePTFE) semipermeable membranes, designed for portal venous delivery of pancreatic islets as a treatment for type 1 diabetes mellitus.</p><p><strong>Materials and methods: </strong>Prototypes with a 0.22 μm pore ePTFE membrane were seeded with murine (approximately 5,000-6,000 islet equivalents [IEQ]) or human (approximately 10,000 IEQ) islets. A benchtop normothermic perfusion circuit simulated intravascular deployment. Glucose-stimulated insulin secretion (GSIS) was assessed in a repeated-measures design (n = 4 devices per experiment); murine islet-seeded devices were perfused under zero (0 mM), low (2.8 mM), and high (28 mM) glucose, and human islet-seeded devices under low and high glucose only, with insulin quantified by ELISA. Computational fluid dynamics (CFD) modeling under idealized, non-physiologic single-fluid conditions evaluated candidate device geometries.</p><p><strong>Results: </strong>Murine islet-seeded devices demonstrated glucose-responsive insulin secretion: 3-hour insulin concentrations were 83 ± 8 vs. 145 ± 20 μIU/mL under low vs. high glucose (p = 0.02), and secretion rates were 5,344 ± 144 vs. 6,795 ± 503 μIU/hr (p = 0.008). Human islet-seeded devices responded concordantly, with 3-hour insulin concentrations of 229 ± 13 vs. 300 ± 17 μIU/mL (p = 0.014).</p><p><strong>Conclusion: </strong>In this benchtop perfusion model, islets housed within an ePTFE-based endovascular stent-graft retained glucose-responsive insulin secretion. In vivo evaluation of islet viability, direct immunoisolation, hemodynamic impact, and long-term function is required before clinical translation.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109140"},"PeriodicalIF":3.1,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ashton Peasley, John Nikitas, Bianca Villegas, Grace Hyun Kim, Eshan Walia, Megumi Yokomizo, Scott Genshaft, Robert Suh, Fereidoun Abtin
{"title":"Five-Year Survival and Durable Local Control After Image-Guided Thermal Ablation for Stage IA Non-Small Cell Lung Cancer.","authors":"Ashton Peasley, John Nikitas, Bianca Villegas, Grace Hyun Kim, Eshan Walia, Megumi Yokomizo, Scott Genshaft, Robert Suh, Fereidoun Abtin","doi":"10.1016/j.jvir.2026.109136","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109136","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate five-year overall survival, cancer-specific survival, local tumor progression-free survival, local recurrence, and durable local control after repeat ablation in patients with Stage IA non-small cell lung cancer treated with image-guided thermal ablation.</p><p><strong>Materials and methods: </strong>This HIPAA-compliant, institutional review board-approved retrospective cohort study included 85 patients with Stage IA non-small cell lung cancer treated with image-guided thermal ablation between 2011 and 2018. Patients had a single target tumor: 16 T1a, 45 T1b, and 24 T1c tumors. Outcomes included technical success, five-year overall survival (OS), cancer-specific survival (CSS), local tumor progression-free survival (LTPFS), local recurrence, durable local control (no further local recurrence after repeat ablation during follow-up), and adverse events. Kaplan-Meier analysis estimated survival outcomes.</p><p><strong>Results: </strong>Median follow-up was 55.6 months. Ablation modalities included microwave ablation in 41 patients, cryoablation in 37, and radiofrequency ablation in 7. Technical success was 100%. Grade 2 or higher adverse events within 90 days occurred in 8 patients (9.4%), all pneumothoraces requiring chest tubes. Five-year OS was 68.2%, 77.4%, and 68.2%; CSS was 100%, 87.2%, and 100%; and LTPFS was 100%, 77.8%, and 100% for T1a, T1b, and T1c tumors, respectively. Overall five-year LTPFS was 92.6%. Local recurrence occurred in 8 patients (9.4%). Six underwent repeat ablation without subsequent recurrence, yielding durable local control in 97.6%.</p><p><strong>Conclusion: </strong>Image-guided thermal ablation provided favorable five-year survival and high durable local control for Stage IA non-small cell lung cancer, supporting ablation as a repeatable and effective treatment option.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109136"},"PeriodicalIF":3.1,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul Soliman, Luke Jones, Mary Serpe, Meaghan Dendy Case, Nicholas Voutsinas
{"title":"Trends in Retraction of Vascular and Interventional Radiology Research.","authors":"Paul Soliman, Luke Jones, Mary Serpe, Meaghan Dendy Case, Nicholas Voutsinas","doi":"10.1016/j.jvir.2026.109134","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109134","url":null,"abstract":"<p><p>Retractions play an important role in maintaining the integrity of vascular and interventional radiology (VIR) literature, yet their causes and trends remain uncharacterized. A search of PubMed, Embase, and the Retraction Watch Database in April 2026 identified 142 retracted VIR articles published since 2000. The leading reasons for retraction were peer-review manipulation (21.1%), intrinsic study errors (14.8%), and submission duplication (11.3%), although 40% of notices did not specify a reason. Most articles originated from China (69%) and addressed interventional oncology (35.2%). Retractions rose sharply in recent years, with 64.7% occurring between 2023 and 2026. The median time from publication to retraction was 14.8 months, and most articles were retracted within two years. Journal impact factor ranged widely (0.60-78.50) and was not associated with time to retraction. These findings highlight peer-review manipulation as a prominent mechanism of misconduct and reaffirm the importance of rigorous peer review and editorial screening.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109134"},"PeriodicalIF":3.1,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149149526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amy R Deipolyi, Michael V Korona, Ashraf Ahmad, Adam Belcher
{"title":"Adaptation and Initial Psychometric Validation of the Clinician Satisfaction with Sedation Instrument (CSSI) for Interventional Radiology.","authors":"Amy R Deipolyi, Michael V Korona, Ashraf Ahmad, Adam Belcher","doi":"10.1016/j.jvir.2026.109131","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109131","url":null,"abstract":"<p><strong>Purpose: </strong>To adapt and psychometrically validate the Clinician Satisfaction with Sedation Instrument (CSSI) for use in interventional radiology (IR), including assessment of reliability and validity.</p><p><strong>Materials and methods: </strong>In this prospective observational study, clinician responses were collected following adult IR procedures performed with IR-administered procedural sedation. The original 21-item CSSI was adapted for IR using face validity assessment and pilot testing, resulting in a 13-item instrument. Internal consistency, exploratory factor analysis, inter-rater reliability, criterion validity, construct validity, and convergent validity were evaluated. A secondary cohort assessed physician-physician agreement.</p><p><strong>Results: </strong>One hundred one procedures generated 272 completed surveys from 12 clinicians (10 nurses, 2 physicians). The adapted CSSI demonstrated excellent internal consistency (Cronbach α = 0.968) and a unidimensional factor structure accounting for 73.1% of variance. Inter-rater reliability was moderate between physicians and nurses (ICC = 0.547) and good among nurses (ICC = 0.763). Physician-physician reliability demonstrated good consistency (ICC = 0.688). CSSI scores increased with patient vocalization severity (P < .001), patient movement (P = .041), sedation-related complications (P < .001), multiple procedures (P < .001), and differed across procedure types (P = .030) and sedation regimens (P < .001). CSSI scores also correlated with deepest procedural sedation level (Spearman r = 0.491, P = .028).</p><p><strong>Conclusion: </strong>The adapted 13-item CSSI demonstrated excellent internal consistency and initial evidence of reliability and validity for measuring clinician satisfaction with procedural sedation in interventional radiology. The instrument shows potential as a standardized clinician-reported outcome measure for future comparative sedation studies.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109131"},"PeriodicalIF":3.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment Response after Radiofrequency Ablation Alone versus Combined Ethanol Ablation and Radiofrequency Ablation in Predominantly Cystic Thyroid Nodules.","authors":"Jiexin Wang, Honglian Zhou, Yuping Yang, Lijuan Liu, Xiaohong Xu, Shixing Zheng, Qiang Huang, Xin Liang","doi":"10.1016/j.jvir.2026.109130","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109130","url":null,"abstract":"<p><strong>Purpose: </strong>To compare longitudinal changes in nodule volume after radiofrequency ablation (RFA) alone versus combined ethanol ablation (EA) and RFA in predominantly cystic thyroid nodules (PCTNs), and to estimate the adjusted treatment effect on achieving a volume reduction rate (VRR) ≥85% at 12 months.</p><p><strong>Materials and methods: </strong>This retrospective single-center study included 184 PCTNs in 176 patients treated with RFA alone (81 nodules) or combined EA and RFA (103 nodules). Nodule volume was assessed at baseline and at 3, 6, and 12 months. Longitudinal volume changes were analyzed using an inverse probability of treatment-weighted mixed-effects model, and 12-month VRR ≥85% using multivariable-adjusted and weighted logistic regression.</p><p><strong>Results: </strong>A VRR ≥85% was more frequent after combined treatment at 3, 6, and 12 months (32.0% vs 13.6%, 61.2% vs 40.7%, and 89.3% vs 70.4%, respectively; all P ≤ .006). In the weighted mixed-effects analysis, mean nodule volume was lower with combined treatment at 6 months (difference, -0.81 mL; 95% CI, -1.47 to -0.15; P = .016) and 12 months (difference, -0.86 mL; 95% CI, -1.43 to -0.30; P = .003), whereas the time-by-treatment interaction was not significant (P = .088). Combined treatment was associated with achieving a VRR ≥85% at 12 months in both multivariable analysis (adjusted OR, 4.17; 95% CI, 1.61-11.70; P = .004) and weighted analysis (OR, 2.56; 95% CI, 1.11-5.90; P = .028).</p><p><strong>Conclusion: </strong>After confounder adjustment, combined EA and RFA was associated with higher odds of achieving a VRR ≥85% at 12 months than RFA alone.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109130"},"PeriodicalIF":3.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endovascular Venous Stenting for Chronic Iliofemoral Venous Obstruction in Post-Thrombotic Syndrome and Non-Thrombotic Iliac Vein Lesion: A Systematic Review and Meta-Analysis of Randomized Controlled Trials and Prospective Single-Arm Clinical Trials.","authors":"Aarushi Batra, Bhumesh Tyagi, Ashok Kumar, Archana Sood","doi":"10.1016/j.jvir.2026.109128","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109128","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate pooled patency, symptomatic, and safety outcomes following dedicated nitinol venous stent placement for symptomatic chronic iliofemoral venous obstruction (CIVO), and to compare outcomes between post-thrombotic syndrome (PTS) and non-thrombotic iliac vein lesion (NIVL) etiologies.</p><p><strong>Methods: </strong>PubMed, Scopus, CENTRAL, and ClinicalTrials.gov were searched from inception to May 2026 for randomized controlled trials and prospective registered single-arm studies evaluating venous stents in symptomatic CIVO. Proportional meta-analysis was conducted using Stata(v19.5). Risk of bias was judged with RoB-2 and ROBINS-I. Certainty of evidence was evaluated with GRADE.</p><p><strong>Results: </strong>13 studies (21 arms; n=1450) were included. Pooled 12-month primary patency was 93% (95% CI 90-97; I<sup>2</sup>=83.17%), declining to 90% and 89% at 24 and 36-months, respectively. Primary patency at 12-months was significantly greater in NIVL (98%; 95% CI 96-99%; I<sup>2</sup>=59.05%) than PTS (84%; 95% CI 81-87%; I<sup>2</sup>=0.0%). A mean reduction of 4.76 points in Venous Clinical Severity Score (VCSS) (0-30 scale; higher score indicates greater severity) and 6.40 points in Villalta score (0-33 scale; ≥5 indicates PTS) was observed. Stent thrombosis occurred more frequently in PTS than NIVL. Exploratory analysis of three RCTs demonstrated reduction in VCSS for stent placement versus standard of care (2.24; 95% CI -3.34 to -1.14; I<sup>2</sup>=0%).</p><p><strong>Conclusion: </strong>Prospective evidence suggests favorable patency and symptom improvement following venous stent placement for symptomatic CIVO, although substantial heterogeneity and low-to-very-low certainty of evidence warrant cautious interpretation. Outcomes differ significantly between PTS and NIVL, reflecting an association between etiology and long-term stent performance.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109128"},"PeriodicalIF":3.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Bravo R, Angie Ostolaza V, María Alejandra Delgado C, Camila Yáñez A, Leonardo Alvarez A, Claudia Moya O
{"title":"Combined Portal and Hepatic Vein Embolization to Enhance the Future Liver Remnant in Pediatric Hepatoblastoma.","authors":"Eduardo Bravo R, Angie Ostolaza V, María Alejandra Delgado C, Camila Yáñez A, Leonardo Alvarez A, Claudia Moya O","doi":"10.1016/j.jvir.2026.109132","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109132","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109132"},"PeriodicalIF":3.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emergency Uterine Artery Embolization for Postpartum Hemorrhage: Hemostatic Outcomes According to Embolic Material and Shock Index, with Subsequent Pregnancy Outcomes.","authors":"Hiroe Ito, Motoki Nakai, Masanori Ishida, Toru Saguchi, Takehiro Kobayashi, Mika Yasutomi, Ryoji Kawai, Ikuto Tatehara, Shuji Bando, Eiji Sugihara, Yukinori Okada, Kazuhiro Saito","doi":"10.1016/j.jvir.2026.109129","DOIUrl":"https://doi.org/10.1016/j.jvir.2026.109129","url":null,"abstract":"<p><strong>Purpose: </strong>To compare hemostatic efficacy and subsequent pregnancy outcomes of gelatin sponge (GS) and n-butyl-2-cyanoacrylate (NBCA) in emergency uterine artery embolization (UAE) for postpartum hemorrhage (PPH), with Shock Index (SI) as an indicator of bleeding severity.</p><p><strong>Materials and methods: </strong>We retrospectively reviewed 51 patients who underwent emergency UAE for uncontrolled PPH between January 2012 and December 2024. Hemostatic outcomes were evaluated in all patients. Forty-eight patients with SI data were stratified into three groups: SI <1.0 (n=19), 1.0≤SI<1.5 (n=18), and SI≥1.5 (n=11). Pregnancy outcomes were assessed in 46 patients with uterine preservation and available SI data.</p><p><strong>Results: </strong>Initial embolization used GS in 44 patients (86.3%) and NBCA in 7 (13.7%). The DIC score was higher in the initial NBCA group than in the initial GS group (median, 9 vs. 7; p = 0.017). Initial embolization succeeded in 41 patients (80.4%), including 34/44 (77.3%) with GS and 7/7 (100%) with NBCA (p=0.320). Of 10 initial GS failures, 8 were converted to NBCA and 2 underwent hysterectomy. Final hemostatic success was achieved in 49 patients (96.1%), including all 8 converted cases. Among 46 patients with uterine preservation and available SI data, 9 achieved pregnancy: 6/31 (19.4%) after GS alone and 3/15 (20.0%) after NBCA, including GS-to-NBCA conversion (p=1.000).</p><p><strong>Conclusion: </strong>NBCA was effective for hemostasis in emergency UAE for PPH, including after conversion from GS. Subsequent pregnancy rates were comparable between GS alone and NBCA through April 30, 2026.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":"109129"},"PeriodicalIF":3.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149139160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}