{"title":"Changes in the American Interventional Radiology literature over a ten-year period (2011-2013 versus 2021-2023).","authors":"Wint T, Ray Ce","doi":"10.1016/j.jvir.2025.07.014","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.014","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark W Little, Sankalp Agarwal, Ibrohim M Khikmatovich, Joan McCabe, Masum Pandey, Andrew L Lewis, Liam Farrissey, Sherzod A Iskhakov
{"title":"First-in-Human Evaluation of a New Resorbable Microspherical Embolic Agent for Genicular Artery Embolization to Treat Pain Secondary to Knee Osteroarthritis.","authors":"Mark W Little, Sankalp Agarwal, Ibrohim M Khikmatovich, Joan McCabe, Masum Pandey, Andrew L Lewis, Liam Farrissey, Sherzod A Iskhakov","doi":"10.1016/j.jvir.2025.07.010","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.010","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the safety and efficacy of Genicular Artery Embolization (GAE) using resorbable microspherical embolic agent to treat pain secondary to knee osteoarthritis.</p><p><strong>Materials and methods: </strong>This prospective, single-arm, unblinded, first-in-human study was performed in 15 patients (12 women, mean age 62.8). GAE was performed with 200 ± 75mm resorbable alginate microspheres (SakuraBead; Crannmed, Galway, Ireland). Primary endpoint was safety, with efficacy evaluated as a secondary endpint using the pain Visual Analogue Scale (VAS) and the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) at baseline, 1, 3, and, 6 months. Adverse events were recorded at all timepoints.</p><p><strong>Results: </strong>GAE was technically successful in all patients. There were six adverse events recorded in six different patients, all were minor and self-limiting (Grade 1). The percentage reduction in VAS, WOMAC Total and WOMAC Pain scores was calculated for individual patients. This showed there was a statistically significant reduction (p<0.001) in the mean VAS score of 76% , 77% and 63% at 1, 3 and 6 months respectively. There was a 78% reduction in WOMAC Total Score at both 1 and 3 months and 76% reduction at 6 months (P<0.01); this was accompanied by a reduction in WOMAC pain of 78%, 81% and 78% at 1, 3 and 6 months respectively (p<0.01).</p><p><strong>Conclusions: </strong>In this limited pilot study, GAE using alginate resorbable microspheres was safe and produced significant improvement in pain and function in patients with KOA maintained to 6-month follow-up.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marwan Moussa, Omar Hamam, Ahmad Maaly, Mohammed Elkholy, Mohamed Farghaly, Godwin Abiola, Salomao Faintuch, Barry Sacks, Anand Vaidya, Muneeb Ahmed, Ammar Sarwar
{"title":"The Aldosteronoma Resolution Score as a Predictive Metric for Outcomes after Radiofrequency Ablation for Primary Aldosteronism.","authors":"Marwan Moussa, Omar Hamam, Ahmad Maaly, Mohammed Elkholy, Mohamed Farghaly, Godwin Abiola, Salomao Faintuch, Barry Sacks, Anand Vaidya, Muneeb Ahmed, Ammar Sarwar","doi":"10.1016/j.jvir.2025.07.011","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.011","url":null,"abstract":"<p><strong>Purpose: </strong>Radiofrequency ablation (RFA) is an emerging treatment for treatment primary aldosteronism (PA). The Aldosteronoma Resolution Score (ARS) is a validated metric for prognostication of complete clinical response after adrenalectomy. The purpose of this study is to validate ARS as a prognosticator for outcomes post-RFA.</p><p><strong>Material and methods: </strong>After IRB approval, patients treated with RFA for a unilateral aldosteronoma between 2007-2023 were retrospectively reviewed. Clinical and biochemical data were collected, including pre- and post-procedural potassium, aldosterone, plasma renin activity levels, blood pressure, number and doses of antihypertensives. Analysis included descriptive analysis and AUC- ROC tests assessing the relation between ARS and outcomes post-RFA. ARS were defined as \"high likelihood of clinical response\" (4-5), \"medium likelihood of clinical response\" (2-3)and \"low likelihood of clinical response\" (0-1). Outcome definitions were complete clinical response (BP< 140/90 mmHg, without antihypertensives), partial clinical response (BP<140/90, requiring less antihypertensives pre-RFA) and absent clinical response (BP<140/90 mmHg, requiring unchanged antihypertensives pre-RFA). ARS correlation with post-RFA biochemical data was performed as an exploratory endpoint.</p><p><strong>Results: </strong>In 59 patients (M 71%) with a mean age 54.4±10.3 years, 15% achieved complete clinical response while 8% had high ARS Score. 46% had partial response while 46% had medium ARS score. 39% had absent clinical response corresponding to 46% who had low ARS score. AUC = 0.891 (95% CI: 0.795-0.987) P<0.001, for predicting complete clinical response.</p><p><strong>Conclusion: </strong>Preliminary evidence demonstrates that ARS can be used for predicting clinical outcomes in PA post-RFA.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Henry Ruhl, Felipe M Berg, Amir A Rahnemai-Azar, Salim Abboud, Agata A Exner
{"title":"Foam Fortification: The Effect of Perfluorocarbon Gases on the Stability of Sclerosing Agent Foams.","authors":"Henry Ruhl, Felipe M Berg, Amir A Rahnemai-Azar, Salim Abboud, Agata A Exner","doi":"10.1016/j.jvir.2025.07.009","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.009","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the impact of incorporating perfluorocarbons (PFCs), specifically C<sub>3</sub>F<sub>8</sub> and C<sub>4</sub>F<sub>10</sub>, on the stability of STS-based foams.</p><p><strong>Materials and methods: </strong>Tessari's method was employed to generate foams. C<sub>3</sub>F<sub>8</sub> and C<sub>4</sub>F<sub>10</sub> were compared with room air due to their known characteristic as gas vesicle stabilizers. Each trial set encompassed ratios of 1:1.5, 2, 3, and 4 mL of STS-to-gas. Foam decay (1 minus percent foam remaining in syringe) was monitored using a 4K camera over 1 hour, followed by hourly snapshots for 3 hours. All trials were repeated in triplicate. Statistical analysis was carried out via one-way ANOVA and, where appropriate, Student's T-test.</p><p><strong>Results: </strong>PFC-stabilized foams exhibited greater stability than room air-stabilized foams, with C<sub>4</sub>F<sub>10</sub> demonstrating the highest stability. Air-stabilized foams fully decayed within 30 minutes, whereas PFCs maintained over 70% foam volume for up to 45 minutes. Notably, a significant decrease in foam stability was observed in the 1:4 ratio of C<sub>3</sub>F<sub>8</sub> between 60 to 180 minutes, a decline not seen in C<sub>4</sub>F<sub>10</sub> foams (p < 0.001). While increasing the STS-to-room air ratio diminished foam stability, it enhanced stability in PFC-stabilized foams. Specifically, the 1:4 STS-to-PFC ratio sustained approximately 15% more foam than the 1:1.5 ratio over 180 minutes, aside from the substantial decrease in C<sub>3</sub>F<sub>8</sub> foams. These findings suggest PFCs may improve the stability of sclerosing foams.</p><p><strong>Conclusion: </strong>C<sub>3</sub>F<sub>8</sub> and C<sub>4</sub>F<sub>10</sub> showed greater stability with STS compared to room air, and C<sub>4</sub>F<sub>10</sub> exhibited better stability over time than C<sub>3</sub>F<sub>8</sub>.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Tilt and Retrieval Challenges with Inferior Vena Cava Filters: Comparison of Original and Anti-Tilting Models of the ALN Filter.","authors":"Sylvain Grange, Pierre Cixous, Géraldine Poenou, Geoffroy Guillaubey, Elie Ayoub, Claire Boutet, Laurent Bertoletti, Rémi Grange","doi":"10.1016/j.jvir.2025.07.005","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.005","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the tilt of the classical ALN® inferior vena cava filter (IVCF) with that of the new Optional Anti-Tilting Filter (OATF) in a single-center retrospective study.</p><p><strong>Materials and methods: </strong>This retrospective study analyzed fluoroscopic images from 539 patients who received an IVCF between April 2012 and March 2023. The primary outcome was the frontal view tilt angle of the IVCF within the IVC at insertion between the ALN classical filter (ACF) and the new OATF. Secondary outcomes included a comparison of tilt between these two filters at retrieval, as well as a correlation between tilt and fluoroscopy time. Imaging and clinical data were collected from hospital databases, and statistical analysis was conducted using regression models.</p><p><strong>Results: </strong>At placement, in the frontal plane, median tilt was significantly lower in the OATF group (5° [2°-10°]) than in the ACF group (10° [6°-15°]) (p<0.01). At retrieval, median frontal plane tilt was significantly lower in the OATF group (3.5° [1°-10°]) than in the ACF group (11° [5°-16.5°]) (p<0.01). Median lateral plane tilt at retrieval was also significantly lower in the OATF group (3° [1°-6.5°]) than in the ACF group (8° [4°-13°]) (p < 0.001). At retrieval, front plane tilt was correlated with fluoroscopy time (Spearman correlation coefficient: 0.165; n=184) (p=0.033).</p><p><strong>Discussion: </strong>These findings indicate that the OATF is associated with reduced tilt compared to the classical model.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christin Fürnstahl, Elif Can, Simone Hammer, Michael Doppler, Niklas Verloh, Birgit Knoppke, Dirk Grothues, Michael Melter, Stefan M Brunner, Hans Jürgen Schlitt, Wibke Uller
{"title":"Improved Outcomes from Prolonged Percutaneous Biliary Drainage in Pediatric Patients with Biliary Stenosis after Liver Transplantation.","authors":"Christin Fürnstahl, Elif Can, Simone Hammer, Michael Doppler, Niklas Verloh, Birgit Knoppke, Dirk Grothues, Michael Melter, Stefan M Brunner, Hans Jürgen Schlitt, Wibke Uller","doi":"10.1016/j.jvir.2025.07.006","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.006","url":null,"abstract":"<p><strong>Purpose: </strong>Biliary complications affect 15-40% of pediatric liver transplants (pLT), with biliary strictures (BS) occurring in 5-23%. Roux-en-Y hepaticojejunostomy is the primary reconstructive technique. This study evaluates patency rates, outcomes of percutaneous transhepatic biliary drainage (PTBD), and predictors of stenosis recurrence.</p><p><strong>Methods: </strong>A retrospective analysis of 47 PTBDs in 40 pediatric patients post-pLT (2009-2019) was performed. Six patients underwent repeated PTBD for recurrent BS. Kaplan-Meier, log-rank, and Cox regression analyses evaluated patency and influencing factors. Management followed institutional protocols with drain upsizing every 6-8 weeks. Median age was 1.8 years (IQR: 0.8-8.2), weight 9.9 kg (IQR: 7.5-19.6).</p><p><strong>Results: </strong>The median interval from pLT to PTBD was 122 days (IQR 55-626). Primary patency was 89.4 % at 1 year and 86.3 % at 5 years, with 15 % restenosis after a median of 8.5 months. Repeat PTBD achieved patency rates of 100 % at 1 year and 83.3 % at 5 years (exploratory). Patency declined with dwell times < 5 months (p = 0.015), biliary leaks limited to the period before or during PTBD (post-PTBD leaks showed no association); hepaticojejunostomy revision, complex portal-vein reconstruction; and low- to moderate-grade hepatic-artery stenosis. Longer dwell time reduced recurrence risk (HR 0.52, 95 % CI 0.30-0.89). Elevated alkaline phosphatase, bilirubin, GGT, and AST were predictive of recurrence (p < 0.05).</p><p><strong>Conclusion: </strong>PTBD ≥5 months improves biliary patency and reduces restenosis risk. Shorter durations increase recurrence risk. Outcomes depend on PTBD duration, vascular status, bile leaks, and surgical complexity. Laboratory changes during and after therapy may indicate recurrent stenosis.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isa Cam, Damla Köksalan, Almotasem O I Shatat, Berrin Cetinarslan, Zeynep Canturk, Ercüment Çiftçi
{"title":"Complete Response to Bland Embolization and Targeted Therapy of an Unresectable, Hemorrhagic, Recurrent Papillary Thyroid Carcinoma.","authors":"Isa Cam, Damla Köksalan, Almotasem O I Shatat, Berrin Cetinarslan, Zeynep Canturk, Ercüment Çiftçi","doi":"10.1016/j.jvir.2025.07.008","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.07.008","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alain Silvestre, Pierre-Francois Lintingre, Nicolas Bouguennec, Benjamin Dallaudiere
{"title":"Bone Marrow Concentrate Intra-Articular Injections for Knee Osteoarthritis: Updated 5-Year Clinical Outcomes in 71 Patients.","authors":"Alain Silvestre, Pierre-Francois Lintingre, Nicolas Bouguennec, Benjamin Dallaudiere","doi":"10.1016/j.jvir.2025.06.026","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.06.026","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmet Günkan, Alperen Elek, Victor Arthur Ohannesian, Lucas Lima Mendes, Umur Anil Pehlivan, Mohamed E M Fouad, Murtaja Satea Shafeea, Romaric Loffroy, Jack Hannallah, Gregory Woodhead, Shamar Young
{"title":"Safety and Effectiveness of Image-Guided Therapies for Giant Hepatic Hemangiomas: A Systematic Review and Meta-Analysis of 2617 Patients.","authors":"Ahmet Günkan, Alperen Elek, Victor Arthur Ohannesian, Lucas Lima Mendes, Umur Anil Pehlivan, Mohamed E M Fouad, Murtaja Satea Shafeea, Romaric Loffroy, Jack Hannallah, Gregory Woodhead, Shamar Young","doi":"10.1016/j.jvir.2025.06.025","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.06.025","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the safety and efficacy of image-guided therapies-including transarterial chemoembolization (TACE), radiofrequency ablation (RFA), microwave ablation (MWA), and percutaneous sclerotherapy (PS)-for the treatment of giant hepatic hemangiomas (GHHs).</p><p><strong>Materials and methods: </strong>A comprehensive search was performed across PubMed, Scopus, and Web of Science, including studies with ≥5 patients reporting image-guided treatment of GHHs. Primary outcomes included technical success, adverse events (AE; classified according to the Society of Interventional Radiology system), clinical success (symptom relief without additional intervention), and radiologic success (≥50% size reduction and/or lack of enhancement on follow-up imaging). A subgroup analysis was performed for GHHs ≥10 cm. Outcomes were analyzed using a random-effects meta-analysis.</p><p><strong>Results: </strong>Twenty-eight studies (2,617 patients; 32.5% men; mean age: 46.1 ± 3.2 years) with 2,996 GHHs, ranging from 4 cm to 30 cm, were included. Of these, 22 were non-comparative, and 6 compared either two image-guided therapies or surgery, reporting outcomes for TACE (n = 13), RFA (n = 7), MWA (n = 6), and PS (n = 4). The pooled technical success rate was 99.9%. Grade 2-4 AEs occurred in 1.64%, with TACE having the lowest rate (0.2%) and RFA the highest (2.1%). Clinical success at final follow-up was 99.9%, while radiological success was 85.7%. Grade 2-4 AEs were significantly higher in the GHHs ≥10 cm subanalysis (10.6%; p < .001), despite similar technical success, radiological, and clinical outcomes.</p><p><strong>Conclusion: </strong>Image-guided therapies are safe and effective for GHHs, achieving high technical, clinical, and radiological success with minimal grade 2-4 AEs. However, for GHHs ≥10 cm, AE rates were higher.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Megan Worthington, Timothy Carlon, David Bamshad, Ricki Gottlieb, Aaron Fischman
{"title":"Anomalous Origins of the Prostatic Artery from the Inferior Mesenteric Artery Identified during Prostatic Artery Embolization.","authors":"Megan Worthington, Timothy Carlon, David Bamshad, Ricki Gottlieb, Aaron Fischman","doi":"10.1016/j.jvir.2025.06.024","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.06.024","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}