Journal of Vascular and Interventional Radiology最新文献

{"title":"Embolization before Ablation of T1b Renal Cell Carcinoma (EMBARC)","authors":"Andrew J. Gunn MD , Kevin Anton MD, PhD , Nishita Kothary MD , Grant D. Schmit MD , S. William Stavropoulos MD , Joshua Richman MD, PhD , Jan O. Jansen MBBS, PhD","doi":"10.1016/j.jvir.2024.10.015","DOIUrl":"10.1016/j.jvir.2024.10.015","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 318-319"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-Stent Restenosis after Carotid Artery Stent Placement Comparing Maximum Plaque Predilation and Postdilation","authors":"Leone Nicola MD,&nbsp;Baresi Giovanni Francesco MD,&nbsp;Covic Tea MD,&nbsp;Pizzarelli Ginevra MD,&nbsp;Lauricella Antonio MD,&nbsp;Silingardi Roberto MD,&nbsp;Gennai Stefano MD","doi":"10.1016/j.jvir.2024.10.026","DOIUrl":"10.1016/j.jvir.2024.10.026","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the incidence of in-stent restenosis (ISR) and ipsilateral neurologic symptoms in patients treated with maximum plaque dilation before stent deployment (max-pre-D) and stent placement followed by angioplasty (post-D) technical variants of carotid artery stent placement at midterm follow-up.</div></div><div><h3>Materials and Methods</h3><div>This was a single-center, real-world, retrospective comparative study of 307 patients treated in a single vascular surgery unit between 2014 and 2018. The follow-up protocol consisted of Doppler US performed at 1, 6, and 12 months and annually thereafter. The primary outcome was to compare the incidence of ISR ≥70% in patients treated with post-D and max-pre-D. Secondary outcomes included between-group comparison of the following: (<em>a</em>) symptomatic ISR, (<em>b</em>) reinterventions, and (<em>c</em>) ipsilateral neurologic events.</div></div><div><h3>Results</h3><div>A total of 270 patients (121 in the max-pre-D group and 149 in the post-D group) fulfilling the inclusion criteria were included in the statistical analysis. Mean follow-up was 30.5 months (SD ± 25.6). The ISR rate was 4.1% (n = 5) in the max-pre-D group and 2.7% (n = 4) in the post-D group, with no significant difference in the survival analysis (log-rank <em>P</em> = .664). Symptomatic ISR and retreatment occurred in 3 patients (33.3% of the total ISR for each outcome). Twenty-one ipsilateral neurologic events occurred, 7 in the max-pre-D group (5.8%) and 14 in the post-D group (9.9%), with no statistically significant difference in survival analysis (log-rank <em>P</em> = .315).</div></div><div><h3>Conclusions</h3><div>ISR and major neurologic events did not differ significantly between the max-pre-D and post-D groups. Max-pre-D seemed to be as effective as post-D technique in midterm follow-up.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 301-309"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Orifice Transluminal Ablation for Head and Neck Tumors","authors":"Daniel Yuxuan Ong MBBS, MMed ,&nbsp;Ming Yann Lim MBBS, MMed ,&nbsp;Hao Li MBBS, MMed, MCI ,&nbsp;Hau Wei Khoo MD, MMed ,&nbsp;Amit Karandikar MBBS ,&nbsp;Uei Pua MBBS, MMed","doi":"10.1016/j.jvir.2024.10.031","DOIUrl":"10.1016/j.jvir.2024.10.031","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 359-362.e1"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microwave Ablation of Refractory Oligometastatic Non–Small Cell Lung Cancer in the Liver","authors":"Ruben Geevarghese MBBS ,&nbsp;Henry Kunin BS ,&nbsp;Elena N. Petre MD ,&nbsp;Rebecca Deng MPH ,&nbsp;Samagra Jain BS ,&nbsp;Vlasios S. Sotirchos MD ,&nbsp;Ken Zhao MD ,&nbsp;Constantinos T. Sofocleous MD, PhD ,&nbsp;Stephen B. Solomon MD ,&nbsp;Etay Ziv MD, PhD ,&nbsp;Erica Alexander MD","doi":"10.1016/j.jvir.2024.10.017","DOIUrl":"10.1016/j.jvir.2024.10.017","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate safety and effectiveness of microwave ablation (MWA) in the treatment of liver metastases (LMs) secondary to non–small cell lung cancer (NSCLC).</div></div><div><h3>Materials and Methods</h3><div>This retrospective study included patients with NSCLC who underwent MWA of LM from March 2015 to July 2022. Local tumor progression-free survival (LTPFS) and overall survival (OS) were estimated using competing risk analysis and the Kaplan-Meier method. Postprocedural adverse events were recorded according to the Common Terminology Criteria for Adverse Events (CTCAE) v5.0.</div></div><div><h3>Results</h3><div>Twenty-three patients with 32 LMs were treated in 27 MWA sessions. The mean dimension of the largest index tumor was 1.96 cm (SD ± 0.75). Technical success was 100%. Technical effectiveness was achieved in 26 (81.3%) of 32 tumors. The median length of follow-up was 37.7 months (interquartile range, 20.5–54.5 months). The median LTPFS was 16.3 months (95% confidence interval [CI], 7.87–44.10 months). The median OS was 31.7 months (95% CI, 11.1–65.8 months). Ablation margin was a significant factor for LTPFS, with tumors ablated without a measurable margin being more likely to progress than those with measurable margins (subdistribution hazard ratios [HRs], 0.008–0.024; <em>P</em> &lt; .001). Older age (HR, 1.18; 95% CI, 1.09–1.28; <em>P</em> &lt; .001) and presence of synchronous lung metastases (HR, 14.73; 95% CI, 1.86–116.95; <em>P</em> = .011) were significant predictors of OS. Serious adverse events (CTCAE Grade ≥3) within 30 days occurred in 2 (7.4%) of 27 sessions, including pulmonary embolus and severe abdominal pain.</div></div><div><h3>Conclusions</h3><div>Percutaneous MWA was a safe treatment for NSCLC LM, with longer survival noted in younger patients and those without synchronous lung tumors.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 266-273"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embolization of diffuse idiopathic pulmonary neuroendocrine cell hyperplasia","authors":"Ryan Kohlbrenner MD,&nbsp;Oskar Kizhner MD","doi":"10.1016/j.jvir.2024.10.029","DOIUrl":"10.1016/j.jvir.2024.10.029","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Page 371"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crossword Puzzle","authors":"","doi":"10.1016/j.jvir.2024.11.010","DOIUrl":"10.1016/j.jvir.2024.11.010","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Page 370"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143170497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transarterial Embolization Using an Inorganic Phosphate Binder Modulates Immunity- and Angiogenesis-Related Factors in a Rat Model of Liver Cancer","authors":"Rong-Guang Luo MD ,&nbsp;Yang-Feng Lv PhD ,&nbsp;Jian-Jun Tang MD ,&nbsp;Ren-Feng Shan MD ,&nbsp;Xiao-Yong Wei MD ,&nbsp;Yan-Shu Li MS ,&nbsp;Chuan-Sheng Xie MS ,&nbsp;Zi-Qiang Liao MS ,&nbsp;Yu-Long Ji BS ,&nbsp;Mei-Diao Kang BS ,&nbsp;Qun Tang PhD","doi":"10.1016/j.jvir.2024.10.010","DOIUrl":"10.1016/j.jvir.2024.10.010","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine how low inorganic phosphate stress (LIPS) induced by sevelamer particle transarterial embolization (S-TAE) affects immune regulation and angiogenesis in hepatocellular carcinoma.</div></div><div><h3>Material and Methods</h3><div>Transcatheter arterial embolization (TAE) using conventional ethiodized oil plus polyvinyl alcohol microspheres and S-TAE, which depletes intratumoral inorganic phosphate, were conducted on a McA-RH7777 orthotopic liver tumor model in rats, followed by the assessment of alterations in immunity-related and angiogenesis-related factors. The cells were cultured under hypoxic conditions and stimulated with LIPS to analyze the modulation of programmed cell death 1 ligand (PD-L1), vascular endothelial growth factor (VEGF)-α, and transforming growth factor-β1 expression using western blotting, quantitative real-time polymerase chain reaction, and immunofluorescence assays. Cell migratory capacity and angiogenesis were also evaluated.</div></div><div><h3>Results</h3><div>TAE increased the expression of neoplastic PD-L1 and VEGF-α, and S-TAE downregulated the expression of PD-L1, VEGF-α, and transforming growth factor TGF-β1 and augmented the infiltration of CD8⁺ T cells, and thereby inhibited angiogenesis and activated anticancer immunity. In vitro, the study demonstrated that LIPS inhibited hypoxia-induced upregulation of PD-L1 expression and the hypoxia-inducible factor-1α/VEGF-α axis. Moreover, LIPS inhibited the tube formation ability of human umbilical vein endothelial cells and the migration ability and epithelial–mesenchymal transition process of cancer cells under hypoxic conditions.</div></div><div><h3>Conclusions</h3><div>S-TAE inhibited the expression of PD-L1 and VEGF-α, thereby activating antitumor immunity and suppressing tumor angiogenesis. The biology of tumors under LIPS suggests the potential therapeutic value of phosphate depletion using sevelamer for S-TAE.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 320-331.e9"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Porcine Model of Arteriovenous Fistula Venous Stenosis Treated with Percutaneous Transluminal Angioplasty","authors":"Prabh G. Singh MBBS ,&nbsp;Sreenivasulu Kilari PhD ,&nbsp;Ahmed S. Negm MBBS ,&nbsp;Joanne M. Pedersen AAS ,&nbsp;Dan R. Montonye DVM ,&nbsp;Kiaran P. McGee PhD ,&nbsp;Jeremy D. Collins MD ,&nbsp;Sanjay Misra MD","doi":"10.1016/j.jvir.2024.10.020","DOIUrl":"10.1016/j.jvir.2024.10.020","url":null,"abstract":"<div><h3>Purpose</h3><div>To develop a porcine model for arteriovenous fistula (AVF) venous stenosis (VS) treated with percutaneous transluminal angioplasty (PTA), and to compare outcomes of plain ordinary balloon angioplasty (POBA) to paclitaxel drug-coated balloon (DCB) angioplasty.</div></div><div><h3>Materials and Methods</h3><div>Twelve castrated male Yorkshire pigs (4–5 months, 35–45 kg) underwent renal artery embolization to induce chronic kidney disease (CKD). Twenty-eight days later, AVF was created by anastomosing the left external jugular vein to left common carotid artery. The pigs were divided into a pilot group (n = 6) for optimizing the AVF technique (euthanized at Day 4) and a definitive group (n = 6) for validating PTA outcomes (euthanized at Day 42). Stenosis developed at juxta-anastomosis 28 days later and was treated with POBA (pilot group, n = 6; definitive group, n = 3) or DCB (definitive group only, n = 3). The definitive group underwent biweekly 4-dimensional flow magnetic resonance (MR) imaging.</div></div><div><h3>Results</h3><div>All animals developed CKD, with significant increases in the levels of blood urea nitrogen (increase of median from 2.6 to 3.2 mmol/L; <em>P</em> &lt; .001) and creatinine (increase of median from 10 to 187 μmol/L, <em>P</em> &lt; .001). In the pilot group, 1 animal had an infected fistula, and AVF patency was 1/5. In the definitive group, the patency was 5/6 because the AVF technique was modified by resecting the sternomastoid muscle and increasing the spatulation. At Day 42 after PTA, the DCB-treated AVF outflow vein showed increasing but statistically insignificant blood flow compared with POBA (DCB, 209.8 mm² ± 64.4, vs POBA, 170.9 mm² ± 95.5; <em>P</em> = .934).</div></div><div><h3>Conclusions</h3><div>A porcine model of AVF VS treated with PTA was developed, with blood flow trends favoring DCB over POBA.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 332-339.e10"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation Pneumonitis—Why Are We Still Guessing?","authors":"Sandra Gad MSc ,&nbsp;Michael Mohansky MBS ,&nbsp;Alex Villalobos MD ,&nbsp;Lourens Du Pisanie MD ,&nbsp;Nima Kokabi MD","doi":"10.1016/j.jvir.2024.10.014","DOIUrl":"10.1016/j.jvir.2024.10.014","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"36 2","pages":"Pages 219-220"},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Embolotherapy for pulmonary arteriovenous malformations in the pediatric population with hereditary hemorrhagic telangiectasias - a retrospective case series.","authors":"Haseeb Mukhtar, Vivek Iyer, Nadir Demirel, Emily C Bendel, Haraldur Bjarnason, Sanjay Misra","doi":"10.1016/j.jvir.2025.01.047","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.01.047","url":null,"abstract":"<p><strong>Purpose: </strong>To document the outcomes of embolotherapy for pulmonary arteriovenous malformation (pAVM) management, and investigate factors associated with pAVM persistence after embolotherapy in pediatric patients with hereditary hemorrhagic telangiectasia (HHT).</p><p><strong>Materials and methods: </strong>Pediatric patients with HHT who received embolotherapy for pAVMs at the institute were retrospectively identified from January 1^st, 1999, to January 31^st, 2024. Cases with adequate clinical and imaging follow-up and without prior pAVM treatment at another institute were included. Demographic, clinical, and procedural data were obtained from the electronic health record. Univariate Cox proportional hazard models were used to determine factors associated with primary pAVM persistence (re-establishment of an arteriovenous connection in a pAVM after the first embolotherapy).</p><p><strong>Results: </strong>Twenty-one patients (median age=15 years; range:3-19 years) underwent embolotherapy for 65 different pAVMs (Median follow-up time=7.56 years; range:0.13-24.4 years). In total, 3 procedural adverse events occurred. Primary persistence occurred in 23.1% of the treated pAVMs with recanalization only being the most common cause of (73.3%) followed by untreated feeders (20.0%) and recanalization along with formation of new collaterals to the pAVM (6.67%). Age less than the median cutoff of 15 years (p=0.044) and greater maximum diameter of the plugs/coils (p=0.011) were significantly associated with primary persistence on univariate analysis.</p><p><strong>Conclusion: </strong>Embolotherapy of pAVMs in pediatric patients with HHT is safe, with a high rate of persistence when predominantly coils are used. The risk of primary persistence was associated with age less than 15 years, and the use of larger diameter plugs/coils.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}