Journal of Vascular and Interventional Radiology最新文献

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Transarterial Embolization Using Imipenem/Cilastatin for Chronic Painful Achilles Tendinopathy Refractory to Conservative Management. 亚胺培南/西司他汀经动脉栓塞治疗顽固性慢性疼痛性跟腱病。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-15 DOI: 10.1016/j.jvir.2025.10.009
Neeraj Kumar, Niraj Nirmal Pandey, Sanjeev Kumar, Aprateem Mukherjee, Vikrant Manhas, Priya Jagia
{"title":"Transarterial Embolization Using Imipenem/Cilastatin for Chronic Painful Achilles Tendinopathy Refractory to Conservative Management.","authors":"Neeraj Kumar, Niraj Nirmal Pandey, Sanjeev Kumar, Aprateem Mukherjee, Vikrant Manhas, Priya Jagia","doi":"10.1016/j.jvir.2025.10.009","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.009","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility, safety, and efficacy of transarterial embolization (TAE) for painful chronic Achilles tendinopathy (AT) refractory to conservative management.</p><p><strong>Materials and methods: </strong>This prospective study included 20 limbs in 18 patients (7 males, mean age: 45.89 ± 9.97 years) with painful chronic AT, not responding to conservative management for ≥3 months. Superselective cannulation of branches from the posterior tibial artery or the peroneal artery supplying the point of maximal pain in the Achilles tendon was performed. Branches showing hypervascular staining were embolized using a suspension of 500mg of imipenem/ cilastatin sodium in 5mL of iodinated contrast agent. Visual analogue scale (VAS) and Victorian Institute of Sports Assessment-Achilles questionnaire (VISA-A) scores were used to assess pain and function at baseline, 1 day, 1 week, 1 month, 3 months, 6 months, 9 months, and 12 months post-procedure.</p><p><strong>Results: </strong>Hypervascular staining at the point of maximal pain was seen in all patients. Branches from the posterior tibial artery or the peroneal artery supplying the area of hypervascular staining could be superselectively embolized in 18/20 limbs, indicating 90% technical success. Significant decrease in VAS score (Median (IQR): 7(7-8) vs. 1(1-2); p<0.0001) and significant increase in VISA-A score (Median (IQR): 29.5(24-33) vs. 68(56-76); p=0.0001) were noted on day 1 post-procedure which persisted through one year of follow-up. Clinical success, defined as a >50% reduction in VAS score, was achieved in 94.44% (17/18) of procedures.</p><p><strong>Conclusions: </strong>TAE is a feasible, safe and effective treatment for alleviating pain associated with chronic AT refractory to conservative management, with a low risk of adverse events.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145314042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous Cryoablation of Small Pancreatic Tumors: An Underestimated Option? 经皮胰腺小肿瘤冷冻消融:一个被低估的选择?
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-15 DOI: 10.1016/j.jvir.2025.10.010
Claudio Sallemi, Flavio Cesare Bodini, Silvia Noventa, Marco Garatti
{"title":"Percutaneous Cryoablation of Small Pancreatic Tumors: An Underestimated Option?","authors":"Claudio Sallemi, Flavio Cesare Bodini, Silvia Noventa, Marco Garatti","doi":"10.1016/j.jvir.2025.10.010","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.010","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145314095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genicular embolization as a therapeutic alternative in tenosynovial giant cell tumour: a case report". 膝关节栓塞作为腱鞘巨细胞瘤的一种治疗选择:1例报告。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-13 DOI: 10.1016/j.jvir.2025.10.006
Leonardo Guedes Moreira Valle, Priscila Mina Falsarella, Jessica Proenca Derze, Breno Boueri Affonso, Francisco Leonardo Galastri, Felipe Nasser
{"title":"Genicular embolization as a therapeutic alternative in tenosynovial giant cell tumour: a case report\".","authors":"Leonardo Guedes Moreira Valle, Priscila Mina Falsarella, Jessica Proenca Derze, Breno Boueri Affonso, Francisco Leonardo Galastri, Felipe Nasser","doi":"10.1016/j.jvir.2025.10.006","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.006","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Direct stent placement vs percutaneous mechanical thrombectomy in selected patients with acute lower limb ischemia: short and long-term outcomes. 急性下肢缺血患者的直接支架置入与经皮机械取栓:短期和长期结果
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-13 DOI: 10.1016/j.jvir.2025.10.007
Nikolaos Galanakis, Angeliki Vouidaski, Nikolaos Kontopodis, Michail E Klontzas, Christos V Ioannou, Elias Kehagias
{"title":"Direct stent placement vs percutaneous mechanical thrombectomy in selected patients with acute lower limb ischemia: short and long-term outcomes.","authors":"Nikolaos Galanakis, Angeliki Vouidaski, Nikolaos Kontopodis, Michail E Klontzas, Christos V Ioannou, Elias Kehagias","doi":"10.1016/j.jvir.2025.10.007","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.007","url":null,"abstract":"<p><strong>Purpose: </strong>Percutaneous mechanical thrombectomy (PMT) has an evolving role in the treatment of acute lower limb ischemia (ALI). However, PMT devices are not always available. This study compares the safety and effectiveness of direct stent placement (DS) technique versus PMT in patients with ALI.</p><p><strong>Materials and methods: </strong>This 10-year retrospective study included 50 selected patients out of 465 patients presented with ALI (SVS/ISCVS IIa: n=24, SVS/ISCVS IIb: n=26). The underlying causes included in-situ thrombosis (n=41) and embolism (n=9). Patients were treated either with DS technique (n=20) involving deployment of self-expanding stents across acute arterial occlusions, or with PMT (n=30) using Angiojet device.</p><p><strong>Results: </strong>Technical success was achieved in all cases. Access-site adverse events (hematoma, dissection, pseudoaneurysm) occurred in 2 patients in DS and 4 patients in PMT group. No cases of reperfusion injury and one case of distal embolization in PMT group was reported. During follow-up, 2 minor and 2 major amputations were performed in DS group and 3 major and 3 minor amputations in PMT group. Primary patency rates for DS and PMT group were 90% vs 78.6% at 1 year, 84.7% vs 74.2% at 2 years and 69.3% vs 69.6% at 3 years, respectively (p=0.789). Amputation-free survival rates for DS and PMT group were 85% vs 86.7% at 1 year, 72.9% vs 77.5% at 3 years and 65% vs 77.5% at 4 years, respectively (p=0.635).</p><p><strong>Conclusion: </strong>DS seems to be a safe and effective bailout treatment option for ALI, when PMT is unavailable, demonstrating comparable outcomes with PMT.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protein-Losing Enteropathy Treated by Endoscopic Embolization of Lymphatic Leakage in Duodenum. 内镜下十二指肠淋巴渗漏栓塞治疗蛋白质丢失性肠病。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-13 DOI: 10.1016/j.jvir.2025.10.005
Deborah Rabinowitz, Gabriele Meyer, Fernando Del Rosario, Maxim Itkin
{"title":"Protein-Losing Enteropathy Treated by Endoscopic Embolization of Lymphatic Leakage in Duodenum.","authors":"Deborah Rabinowitz, Gabriele Meyer, Fernando Del Rosario, Maxim Itkin","doi":"10.1016/j.jvir.2025.10.005","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.005","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145304306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Strategies to Optimize Success in Breast Cancer Cryoablation. 优化乳腺癌冷冻消融成功率的策略。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-11 DOI: 10.1016/j.jvir.2025.09.039
Nikiforos Vasiniotis Kamarinos, Peter J Littrup, Constantinos T Sofocleous, Stephen B Solomon, Robert C Ward
{"title":"Strategies to Optimize Success in Breast Cancer Cryoablation.","authors":"Nikiforos Vasiniotis Kamarinos, Peter J Littrup, Constantinos T Sofocleous, Stephen B Solomon, Robert C Ward","doi":"10.1016/j.jvir.2025.09.039","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.09.039","url":null,"abstract":"<p><p>Breast cryoablation is a minimally invasive procedure that has demonstrated feasibility, tolerability, and effectiveness in eradicating small breast cancers. The integration of multimodal imaging systems is crucial for optimal patient selection, precise tumor targeting, and complete tumor eradication. Expanding the use of cryoablation to larger tumors may be feasible by leveraging established ablation techniques, such as ablation margin confirmation and post-ablation biopsy.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145287562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cryoablation Protocols for Primary and Metastatic Lung Tumors: A Systematic Review and Meta-analysis Evaluating Effectiveness and Safety of Percutaneous Cryoablation of Pulmonary Tumors. 原发性和转移性肺肿瘤的冷冻消融方案:一项评估经皮肺肿瘤冷冻消融有效性和安全性的系统综述和荟萃分析。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-09 DOI: 10.1016/j.jvir.2025.10.004
Arman Sarshoghi, Arash Sarshoghi, Maxime Tetu, Calvin S H Ng, Lonny Yarmus, Patrick Bourgouin, Stephen B Solomon, Felix Herth, Robert P Liddell, Moishe Liberman
{"title":"Cryoablation Protocols for Primary and Metastatic Lung Tumors: A Systematic Review and Meta-analysis Evaluating Effectiveness and Safety of Percutaneous Cryoablation of Pulmonary Tumors.","authors":"Arman Sarshoghi, Arash Sarshoghi, Maxime Tetu, Calvin S H Ng, Lonny Yarmus, Patrick Bourgouin, Stephen B Solomon, Felix Herth, Robert P Liddell, Moishe Liberman","doi":"10.1016/j.jvir.2025.10.004","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.004","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review and meta-analysis aimed to evaluate 1-year local tumor control (LTC) after percutaneous cryoablation for lung tumors, and to identify procedural protocol and patient/tumor characteristics associated with improved outcomes.</p><p><strong>Methods: </strong>A systematic search of PubMed, EMBASE and Web of Science was conducted. The primary outcome was LTC at 1 year. Secondary outcomes included the identification of factors associated with LTC and pooled adverse event rates, such as freezing lengths, number of cycles, tumor characteristics, and more. Data were pooled using a random-effects model, and meta-regression was used to analyze factors affecting LTC.</p><p><strong>Results: </strong>Nineteen studies (786 patients, 1048 tumors) yielded a pooled 1-year LTC of 90.5% (95% CI, 85.1%-94.1%). Multivariable meta-regression showed that smaller tumor size was significantly associated with improved LTC. Univariable analysis also identified that superior LTC was associated with a triple freeze-thaw protocols (vs. double), a shorter first freeze duration, a longer final freeze duration, and ending the procedure with a thaw cycle. The incidence of adverse events (CTCAE Grade ≥3) was 4.9% (95% CI: 2.9%-6.9%), with pneumothorax most common (28% of cases).</p><p><strong>Conclusion: </strong>Percutaneous cryoablation demonstrates high effectiveness for lung tumor control. Superior 1-year LTC is associated with smaller tumor size and a triple freeze-thaw protocol characterized by a short initial freeze followed by longer subsequent freezes. These findings provide a data-driven basis for standardizing cryoablation techniques.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Marked clinical improvement of hepatopulmonary syndrome in an adult following coil embolization of a portosystemic shunt. 成人门系统分流线圈栓塞后肝肺综合征的显著临床改善。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-09 DOI: 10.1016/j.jvir.2025.10.001
Akira Yamamoto, Atsushi Jogo, Ken Kageyama, Shohei Harada, Shigeaki Higashiyama, Yukio Miki
{"title":"Marked clinical improvement of hepatopulmonary syndrome in an adult following coil embolization of a portosystemic shunt.","authors":"Akira Yamamoto, Atsushi Jogo, Ken Kageyama, Shohei Harada, Shigeaki Higashiyama, Yukio Miki","doi":"10.1016/j.jvir.2025.10.001","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.10.001","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and Efficacy of Transarterial Chemoembolization for Caudate Lobe Hepatocellular Carcinoma: Long-Term Clinical Outcomes. 经动脉化疗栓塞治疗尾状叶肝癌的安全性和有效性:长期临床结果。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-09 DOI: 10.1016/j.jvir.2025.09.038
Eunbyeol Ko, Jin Hyoung Kim, Jihoon Kim, Gun Ha Kim, Heung-Kyu Ko, Hee Ho Chu, Ji Hoon Shin, Dong Il Gwon, Byung Soo Im, Gi-Young Ko
{"title":"Safety and Efficacy of Transarterial Chemoembolization for Caudate Lobe Hepatocellular Carcinoma: Long-Term Clinical Outcomes.","authors":"Eunbyeol Ko, Jin Hyoung Kim, Jihoon Kim, Gun Ha Kim, Heung-Kyu Ko, Hee Ho Chu, Ji Hoon Shin, Dong Il Gwon, Byung Soo Im, Gi-Young Ko","doi":"10.1016/j.jvir.2025.09.038","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.09.038","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the safety and effectiveness of transarterial chemoembolization (TACE) as first-line treatment for single caudate lobe hepatocellular carcinoma (HCC).</p><p><strong>Materials and methods: </strong>107 treatment-naive patients who received TACE between 2006 and 2023 as first-line treatment for single caudate lobe HCC were retrospectively evaluated. Adverse events, radiologic tumor response, progression-free survival (PFS), and overall survival (OS) following TACE were investigated. Periprocedural variables related to complete response (CR) and OS were investigated using multivariable regression analyses.</p><p><strong>Results: </strong>Complete TACE (cisplatin, ethiodized oil and gelatin foam particles) through all tumor-feeding caudate arteries was possible in 73% of the study patients. The severe adverse event rate was 2.8%. A CR at 1 month after TACE was achieved in 67% of the study patients and multivariable analysis showed that complete TACE (P < .001; odds ratio [OR], 42.86) and a single tumor-feeding artery (P = .002; OR, 8.04) were significant predictors of a CR. The median PFS after TACE was 29 months. After TACE, the 3-, 5-, and 10-year OS rates were 62%, 46%, and 33%, respectively, and the median OS was 53 months. Multivariable analysis revealed four significant periprocedural risk factors: incomplete TACE (P = .004; hazard ratio [HR], 2.69), multiple tumor-feeding arteries (P = .04; HR, 2.02), Child-Pugh class B (P = .003; HR, 2.91), and advanced stage HCC (P = .02; HR, 3.43).</p><p><strong>Conclusions: </strong>TACE appears to be a safe and potentially effective first-line treatment option, with long PFS, for patients with single HCC located in the caudate lobe.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Catheter-Directed Thrombolysis Device Type and Dosing on Treatment Outcomes in Intermediate-Risk Pulmonary Embolism: A Randomized Controlled Trial Post Hoc Analysis. 评价导管导向溶栓装置类型和剂量对中危肺栓塞治疗结果的影响:一项随机对照试验事后分析。
IF 2.6 3区 医学
Journal of Vascular and Interventional Radiology Pub Date : 2025-10-08 DOI: 10.1016/j.jvir.2025.09.037
Carin F Gonsalves, Stefan Stortecky, Samuel Horr, Orestis Pappas, Ripal T Gandhi, Keith Pereira, Jay Giri, Sameer J Khandhar, Ezana M Azene, Fakhir Elmasri, Jonathan Lindquist, Wissam A Jaber
{"title":"Evaluation of Catheter-Directed Thrombolysis Device Type and Dosing on Treatment Outcomes in Intermediate-Risk Pulmonary Embolism: A Randomized Controlled Trial Post Hoc Analysis.","authors":"Carin F Gonsalves, Stefan Stortecky, Samuel Horr, Orestis Pappas, Ripal T Gandhi, Keith Pereira, Jay Giri, Sameer J Khandhar, Ezana M Azene, Fakhir Elmasri, Jonathan Lindquist, Wissam A Jaber","doi":"10.1016/j.jvir.2025.09.037","DOIUrl":"https://doi.org/10.1016/j.jvir.2025.09.037","url":null,"abstract":"<p><strong>Purpose: </strong>To assess if catheter-directed thrombolysis (CDT) treatment heterogeneity in the multicenter [REDACTED] RCT is associated with differences in pulmonary embolism (PE) clinical outcomes.</p><p><strong>Materials and methods: </strong>All [REDACTED] CDT arm patients were eligible for post hoc analysis, excluding those treated with multiple CDT device types (n=8), non-tPA thrombolytics (n=10), or pharmacomechanical CDT (n=12). Patients were grouped by treatment: ultrasound-accelerated CDT (USAT) or standard CDT (SCDT). Treatment protocols were assessed, and clinical, safety, and quality-of-life outcomes were compared at discharge/7 days, 24 hours, and/or 30 days.</p><p><strong>Results: </strong>159 USAT and 87 SCDT patients were included. Longer mean treatment duration (12.4 vs 20.8 hours, p<0.001), higher mean thrombolytic dose (17.2 vs 23.4mg tPA, p<0.001), and more ICU stays >24 hours (57.4% vs 80.5%, p<0.001) were identified in the SCDT group. However, in-hospital outcomes were not different, including all-cause mortality (0.0% vs 1.1%, p=0.35), intracranial hemorrhage (0.6% vs 0.0%, p=1.00), major bleeding (5.7% vs 10.3%, p=0.20), and clinical deterioration and/or bailout (5.0% vs 5.7%, p=0.77). RV/LV ratio reduction (19.9% vs 23.1%, p=0.10) and respirations per minute (20.0 vs 19.9, p=0.62) were not statistically different at the 24-hour visit. PEmb-QoL (18.5 vs 23.0, p=0.18) and EQ-5D-5L (0.84 vs 0.81, p=0.85) were also not different at the 30-day visit.</p><p><strong>Conclusion: </strong>Treatment duration and tPA dose were significantly lower in patients treated with USAT; however, clinical outcomes did not differ significantly between USAT and SCDT. This suggests that the primary analysis of [REDACTED] may be generalizable to tPA-based CDT treatment protocols currently in use.</p>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145276524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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