Journal of Vestibular Research-Equilibrium & Orientation最新文献

{"title":"Exploring the preventive effect of sodium valproate on benign recurrent vertigo: A case series and literature review.","authors":"Jun Cao, Liuliu Xiong, Runtao Zhang, Ruiqi Jia, Juanjuan Zhang, Yajuan Hu, Le Wu, Jingye Wang","doi":"10.1177/09574271261473595","DOIUrl":"https://doi.org/10.1177/09574271261473595","url":null,"abstract":"<p><p>BackgroundBenign recurrent vertigo (BRV) accounts for a high proportion of episodic vestibular syndrome (EVS) patients. To date, randomized controlled trials and guidelines are lacking, and preventive treatment has not been established.ObjectiveIn clinical practice, we have found that sodium valproate has excellent effect on reducing vertigo attacks in BRV patients. Herein, these cases were collected and analyzed to share our clinical experience.MethodsIn this retrospective case series, we evaluated 84 patients with BRV or vestibular migraine (VM) who received prophylactic treatment with sodium valproate (400-500 mg/day) between April 2022 and July 2024. The primary clinical outcomes were the proportion of patients achieving a ≥50% reduction in monthly vertigo days (50% reduction rate) and the complete remission rate. Patients who achieved complete symptom resolution and subsequently discontinued medication were monitored to assess post-withdrawal recurrence rates.ResultsA total of 84 patients were enrolled, including 43 in the BRV group and 41 in the VM group. After 3 months of prophylactic treatment with sodium valproate, 91.1% of patients had a 50% reduction rate in monthly vertigo days and 71.4% had complete remission. There was no significant difference in preventive efficacy between the VM group and BRV group (<i>p</i> = 0.348). There was no significant difference in the cumulative recurrence rates between different preventive treatment courses (<6 and ≥6 months) (<i>p</i> = 0.907). The cumulative recurrence rate after discontinuing medication was 38.2% at 3 months, and this rate after 6 months was 70.0%. Among the 25 patients who experienced recurrence, 44.0% needed to undergo prophylactic treatment again.ConclusionLow-dose sodium valproate showed a good preventive effect in patients with BRV, comparable to that in patients with VM.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261473595"},"PeriodicalIF":1.2,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High beta activity tracks disease state in persistent postural-perceptual dizziness: A longitudinal quantitative EEG study.","authors":"Suk Jae Kim, Chi-Hun Kim, Sookyung Ryoo, Jaechun Hwang, Jae-Hyun Park, Jung Min Seo, Sangil Byun, Kyungjin Yang, Woon-Hong Yeo","doi":"10.1177/09574271261471781","DOIUrl":"https://doi.org/10.1177/09574271261471781","url":null,"abstract":"<p><p>BackgroundPersistent postural-perceptual dizziness (PPPD) is a chronic vestibular disorder lacking objective tools for monitoring disease activity. Quantitative electroencephalography (qEEG) has identified cortical hyperexcitability in migraine, but whether analogous patterns exist in PPPD and reverse with treatment is unknown. We investigated high beta (25-30 Hz) activity as a state-dependent biomarker for PPPD.MethodsThis retrospective longitudinal study analyzed 19-channel resting-state qEEG from 163 unmedicated PPPD patients, 86 healthy controls (HC), and 67 vestibular migraine (VM) patients as a dizzy control group at a specialized neurology clinic. Absolute power was z-score normalized against an age-adjusted reference database. The primary outcome was the number of electrodes with high beta absolute power z-score > +1.96; the continuous mean high beta z-score served as a confirmatory outcome. Patients were followed through pharmacotherapy, with qEEG repeated at follow-up (<i>n</i> = 107) and at relapse after discontinuation (<i>n</i> = 23).ResultsHigh beta electrode counts were graded across groups and highest in PPPD (median: HC 2 [IQR 0-4], VM 7 [3-13], PPPD 16 [12-18]; all pairwise <i>p</i> < 0.001), discriminating PPPD from HC with an AUC of 0.956 (OR = 1.53 per electrode; 95% CI 1.38-1.69); the continuous mean z-score yielded a comparable AUC (0.948). Within PPPD, high beta count was not confounded by age, sex, comorbid migraine, or anxiety (all <i>p</i> > 0.30). Marked responders (n = 76) showed near-normalization of high beta electrode count (17 → 2.5; Cohen's d = 2.58), whereas partial responders (<i>n</i> = 31) showed smaller reductions (15 → 11; <i>p</i> < 0.001). Clinical improvement correlated with reduction in high beta electrode count (ρ = 0.509; <i>p</i> < 0.001). Relapse after discontinuation produced a V-shaped trajectory (<i>n</i> = 23; 15 → 2 → 13).ConclusionsOn qEEG, high beta-trans-diagnostic but most pronounced in PPPD-represents a promising state-dependent biomarker. Its cross-sectional elevation versus controls establishes it as a valid marker, while its differential reduction with treatment and V-shaped relapse trajectory support its potential as a clinically accessible metric for within-subject monitoring of disease activity in PPPD. These findings warrant multicenter, prospective validation.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261471781"},"PeriodicalIF":1.2,"publicationDate":"2026-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral vestibular hypofunction: Are the Barany Society criteria too strict?","authors":"Nicole A Ritter, Danielle M Cassels, David Kayekjian, John F Mills, Shaun A Nguyen, Habib G Rizk","doi":"10.1177/09574271261471102","DOIUrl":"https://doi.org/10.1177/09574271261471102","url":null,"abstract":"<p><p>BackgroundBilateral vestibular hypofunction (BVH) is a debilitating condition presenting acutely or progressively with oscillopsia, floating sensation, imbalance, and disequilibrium.ObjectiveThis study aims to identify the sensitivity of the Barany Society criteria for definitive diagnosis of patients with symptoms of BVH but not meeting the strict criteria and to explore the dissociation of objective testing and subjective patient experience.MethodsRetrospective case study of patients (<i>n</i> = 71) diagnosed at a tertiary vestibular clinic between 2015 and 2021. Diagnostic vestibular testing included caloric testing, rotary chair, and video head impulse testing (vHIT) to quantify vestibular function for definitive diagnosis. Subjective data was collected by means of questionnaires.ResultsThe sensitivity of Barany Society criteria for definite BVH in any vestibular test was 49% (<i>n</i> = 35). The highest sensitivity for an individual test was vHIT (51%). Those meeting Barany Society criteria had a mean Dizziness Handicap Inventory (DHI) score of 59.5 in comparison to 66.7 in those meeting expansive criteria.ConclusionsBarany Society criteria show poor sensitivity (49%). When comparing this criterion with the more widely used expansive criteria, about 50% of patients in our population will be excluded from a BVH diagnosis. This is compounded with the fact that those meeting Barany Society criteria and expansive criteria were at large not significantly different in terms of symptoms types, chronicity, postural stability, and subjective disability. It should be considered that the definite BVH category may need to be renamed \"vestibular areflexia\" since patients with less severe dysfunction on reflexive testing may still have similar disability from symptoms and can be characterized as having BVH.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261471102"},"PeriodicalIF":1.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148563583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuroticism and functional burden in chronic dizziness: A clinical cross-sectional observational study using the Eysenck Model and Dizziness Handicap Inventory.","authors":"Alida Naudé, Amisha Kanji","doi":"10.1177/09574271261465715","DOIUrl":"10.1177/09574271261465715","url":null,"abstract":"<p><p>BackgroundChronic dizziness is a multidimensional condition often influenced by psychological factors. Among these, personality traits such as neuroticism have been linked to heightened symptom perception and disability. However, few studies have systematically examined the relationship between neuroticism, functional burden, and diagnostic characteristics in a population with clinical dizziness.ObjectiveTo investigate the relationship between perceived dizziness-related handicap and neuroticism as a personality trait among patients referred to a multidisciplinary dizziness and balance clinic.MethodsThis observational study included 247 adult patients with persistent dizziness referred to a specialist clinic. Patients completed the Eysenck Personality Questionnaire (EPQ) and the Dizziness Handicap Inventory (DHI). Clinical data included diagnosis category, duration of symptoms, fall history, comorbidities, and consultation history. Statistical analyses included Spearman correlations, ANOVA, chi-square tests, cluster analysis, and multivariate linear regression.ResultsNeuroticism was significantly correlated with higher DHI scores (ρ = 0.39, <i>p</i> < 0.001) and a greater number of healthcare consultations (ρ = 0.19, <i>p</i> = 0.003). It was not associated with duration of symptoms or fall history. A chi-square test indicated a significant association between the neuroticism category and diagnosis category (χ² = 32.02, <i>p</i> = 0.043), with higher neuroticism observed in functional and central disorders. Cluster analysis revealed three psychological-clinical subgroups varying in emotional burden, functional disability, and comorbidity profiles. In regression modelling, neuroticism was the only significant predictor of DHI score (<i>p</i> < 0.001), independent of diagnosis or symptom duration.ConclusionPersonality domains, especially neuroticism, are strong predictors of perceived functional burden in patients with chronic dizziness. These findings underscore the importance of incorporating psychological assessment into the clinical evaluation to further facilitate tailored interventions for the management of dizziness. Personality profiling may help identify high-burden subgroups and guide individualized, multidisciplinary care strategies.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261465715"},"PeriodicalIF":1.2,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation and cultural adaptation of the subscales vestibular activities and participation questionnaire (SVAP) into Puerto Rican Spanish.","authors":"Melanie Méndez Malpica, Sofía Ortiz Quiñones, Aurelis Rodríguez Collazo, Eduin Hernández Canaca, Kristian Pamias Velázquez","doi":"10.1177/09574271261454951","DOIUrl":"https://doi.org/10.1177/09574271261454951","url":null,"abstract":"<p><p>BackgroundThe Subscales Vestibular Activities and Participation Measure Questionnaire (SVAP) measures limitations in activities and restrictions in participation in patients with vestibular conditions. This questionnaire has undergone a translation and cultural adaptation process from English to several languages.ObjectivesThe objectives of the study were to translate and culturally adapt the SVAP from English to Puerto Rican Spanish and to administer the translated instrument to a sample of patients with vestibular disorders in Puerto Rico to determine its reliability.MethodA quantitative methodological study was conducted to translate and culturally adapt the SVAP to a Spanish version following a 7-stage process, obtaining as a result a translated questionnaire into Spanish (SVAP-E). The psychometric evaluation was carried out through internal consistency, where 30 participants of both sexes, from 21 to 85 years old, with vestibular disorders were recruited.ResultsA Cronbach's alpha coefficient of 0.90 was obtained for the SVAP-E. Subscale A analysis showed a Cronbach's alpha coefficient of 0.81 and 0.84 for subscale B.ConclusionThis study supports the Puerto Rican Spanish version of the SVAP as a questionnaire with excellent reliability that could be used to identify activity limitations and restrictions in participation of patients with vestibular conditions.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"9574271261454951"},"PeriodicalIF":1.2,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148399825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Objective and subjective investigation of the cervical component in patients with peripheral vestibulopathy.","authors":"Lucas Resende Lucinda Mangia, Debora Emi Shibukawa, Letícia Leahy, Rafaela de Almeida Lara, Vinícius Monteiro de Oliveira, Rita de Cássia Cassou Guimarães","doi":"10.1177/09574271251393644","DOIUrl":"10.1177/09574271251393644","url":null,"abstract":"<p><p>BackgroundDespite the role attributed to cervical proprioception in balance control, the impact of cervical dysfunction on patients with dizziness remains largely elusive.ObjectiveTo investigate the effects of cervical abnormalities on the quality of life and balance control of patients with unilateral peripheral vestibulopathy.MethodsThis was an observational cross-sectional study. Sixty-one patients with dizziness of peripheral origin were enrolled. They filled out clinical questionnaires, the Dizziness Handicap Inventory (DHI), and the Neck Disability Index (NDI). Twenty-four individuals without vestibular or neck complaints were used as controls. The participants underwent the Cervical Joint Position Error Test (CJPT) and a static posturography.ResultsPatients with dizziness showed worse CJPT results (p = 0.0003). During conditions 1 and 3 of posturography, patients with cervical symptoms performed particularly worse compared to those without them. Also, their mean DHI was higher (<i>p</i> = 0.014). DHI and the CJPT results correlated in the case group (r = 0.32; p = 0.012). In the subgroup with cervical complaints, the NDI and DHI scores showed a moderate correlation (r = 0.540; <i>p</i> = 0.0001).ConclusionCervical proprioception correlated with the DHI scores in patients with dizziness. Patients with vestibular disorders with cervical complaints showed poorer results in balance control. Among them, the scores of self-perceived handicap of cervical complaints and dizziness correlated.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"253-262"},"PeriodicalIF":3.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional neuroimaging features for predicting the transition from benign paroxysmal positional vertigo to persistent postural-perceptual dizziness.","authors":"Wei Fu, Ya Bai, Feng He, Yacheng Lu, Junliang Han, Xiaoming Wang","doi":"10.1177/09574271251407403","DOIUrl":"10.1177/09574271251407403","url":null,"abstract":"<p><p>ObjectivesBenign paroxysmal positional vertigo (BPPV) is a prevalent triggers of persistent postural-perceptual dizziness (PPPD). The maladaptation of brain function may be one of the pathophysiology in PPPD. This study aims to identify brain functional neuroimaging features and establish prediction models to predict PPPD after BPPV.MethodsThe diagnosis of BPPV and PPPD was based on the criteria established by the Bárány Society. Patients with posterior semicircular canal BPPV were treated using the Epley maneuver. Patients with geotropic lateral canal BPPV were treated with the barbecue rotation maneuver, while those with apogeotropic lateral canal BPPV were treated using the Gufoni maneuver. After successful canalith repositioning maneuver treatment, the patient underwent resting-state functional magnetic resonance imaging (fMRI) scan. Using feature selection and extraction techniques, six machine learning algorithms were implemented to predict PPPD. The models were trained with 5-fold cross-validation, and performance was evaluated using the receiver operating characteristic curve (AUC), accuracy, precision, recall, and F1 score (F1).ResultsA total of 101 patients were included in the final analysis, comprising 64 patients without PPPD (non-PPPD) and 37 patients with PPPD (PPPD). A total of 22 functional neuroimaging features were identified to be closely associated with PPPD after BPPV. Among the six machine learning algorithms, the Multilayer Perceptron model exhibited superior performance, with an AUC of 0.93, a recall of 0.82, a precision of 0.83, an accuracy of 0.82, and an F1 score of 0.82. SHAP analysis identified the most influential resting-state fMRI features in this model. For the top 10 important resting-state fMRI features, 3 features overlapped in all six machine learning algorithms. These features include FC between the vermis 3 and the superior frontal gyrus, orbital part, DC in the cerebellum 7b, left, and FC between the Heschl gyrus, left, and the caudate, right.ConclusionsThese findings provide brain functional neuroimaging features which may be closely associated with the transition from BPPV to PPPD, thereby offering a valuable tool for the early detection of PPPD.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"220-231"},"PeriodicalIF":3.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145851509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of otolith dysfunction on postural stability and quality of life: A prospective, case-control study.","authors":"Courtney D Hall, Mark E Dula, Faith W Akin","doi":"10.1177/09574271251391631","DOIUrl":"10.1177/09574271251391631","url":null,"abstract":"<p><p>BackgroundVestibular evoked myogenic potentials (VEMPs) are widely used to assess the otolith organs; however, the clinical significance of otolith organ dysfunction is unclear.ObjectiveThe primary purpose was to determine the functional consequences of otolith dysfunction on postural stability and quality of life in U.S. Veterans.MethodsA prospective case-control design was used, and 124 participants (21-84 years) were grouped based on comprehensive vestibular testing. Caloric and vertical canal video head impulse testing were used to determine semicircular canal function. Cervical and ocular VEMP testing determined otolith organ function. Three vestibular site-of-lesion groups (Otolith Only, Otolith + Canal, and Canal Only) and two control groups (Dizzy Control and Non-Dizzy Control) completed measures of quality of life and multiple measures of postural control.ResultsANCOVAs indicated significant group differences for measures of quality of life and postural stability. All vestibular groups (Otolith Only, Otolith + Canal, and Canal Only) reported significantly worse quality of life than Non-Dizzy Controls. The Otolith + Canal group performed significantly worse than the Otolith Only group and both control groups on the functional gait assessment and preferred gait speed.ConclusionsSimilar to isolated semicircular canal dysfunction, isolated otolith dysfunction may negatively impact quality of life, and in conjunction with semicircular canal dysfunction, may also negatively impact postural stability.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"239-252"},"PeriodicalIF":3.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived sense of direction in persons with dizziness and balance disorders.","authors":"Fai A Alradady, Pamela M Dunlap, Patrick J Sparto, Brooke N Klatt, Joseph M Furman, Susan L Whitney","doi":"10.1177/09574271251389499","DOIUrl":"10.1177/09574271251389499","url":null,"abstract":"<p><p>BackgroundSense of direction (SOD) can be affected in patients with vestibular dysfunction.ObjectiveTo record differences in self-perceived sense of direction using the Santa Barbara Sense of Direction scale (SBSOD) in persons with dizziness and balance disorders over time. To determine relationships between self-perceived sense of direction and the Dizziness Handicap Inventory (DHI), Activities-specific Balance Confidence (ABC) scale, and Gait Disorientation Test (GDT).MethodsIn this prospective cohort study, 56 participants completed the SBSOD at three time points: self-recalled SOD before dizziness onset (pre-dizziness), SOD at initial evaluation (SBSOD-Eval), and SOD 3 months post-evaluation (SBSOD-3M). Participants completed DHI, ABC, and GDT at baseline. Repeated measures ANOVA and Spearman's correlation were used for analysis.ResultsMean SBSOD scores were 4.8 (SD ± 1.1) pre-dizziness; 4.6 (SD ± 1.1) at evaluation; and 4.5 (SD ± 1.2) at 3 months. Significant differences were found between pre-dizziness versus evaluation (<i>p</i> = .03) and pre-dizziness versus three months (<i>p</i> = .02). SBSOD-Eval had significant negative correlation with DHI total score (r = -0.3, <i>p</i> = .019), significant positive correlation with ABC score (r = 0.4, <i>p</i> < .001), and no correlation with GDT.ConclusionsOn average, participants reported that their sense of direction was worse after the onset of dizziness. A better SBSOD was significantly correlated with higher disability levels and better balance confidence.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"232-238"},"PeriodicalIF":3.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145402602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Individual-difference factors in visually induced motion sickness and vection: Findings from multiple studies on field dependence, age, and biological sex.","authors":"Behrang Keshavarz, Polina Andrievskaia, Stefan Berti","doi":"10.1177/09574271251388971","DOIUrl":"10.1177/09574271251388971","url":null,"abstract":"<p><p>The illusion of self-motion provoked by dynamic visual stimulation is known as vection and is a common phenomenon when using visual displays such as virtual reality, video games, or movie theatres. Vection has been historically linked to visually induced motion sickness (VIMS), a phenomenon similar to traditional motion sickness characterized by various symptoms including nausea, fatigue, or eyestrain. Many factors are associated with an individual's susceptibility to VIMS and vection, but their impact is not well understood. Here, we investigated how field dependence, biological sex, and age are linked to the occurrence of VIMS and vection. To achieve this, we combined the datasets from four independent experimental studies with a pooled sample size of N = 336, including 237 younger and 99 older adults. Our results demonstrated that younger adults experienced significantly more VIMS compared to older adults and that women reported more VIMS than men (although this effect was rather weak). Additionally, field dependence was positively correlated with vection in younger adults, but no relationship between field dependence and VIMS was found. Overall, the findings from this study suggest that field dependence is not a relevant factor related to VIMS. Interestingly, older adults seem to be at lower risk of experiencing VIMS, which is encouraging considering that many novel applications are tailored towards an ageing population for rehabilitation or training purposes.</p>","PeriodicalId":49960,"journal":{"name":"Journal of Vestibular Research-Equilibrium & Orientation","volume":" ","pages":"193-206"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13216572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145379584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}