Journal of Veterinary Internal Medicine最新文献

{"title":"Effects of an Iso-Osmotic Chloride-Free Solution With High Strong Ion Difference vs. Ringer's Lactate on Non-Lactate Metabolic Acidosis in Dogs","authors":"Roberto Rabozzi,&nbsp;Stefano Oricco","doi":"10.1111/jvim.70099","DOIUrl":"https://doi.org/10.1111/jvim.70099","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Metabolic acidosis is a common acid–base disorder in critically ill dogs, with fluid therapy being a key but debated treatment. Sodium bicarbonate's risks have spurred interest in safer alternatives such as sodium lactate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To compare the efficacy of a chloride-free, high strong ion difference solution (H-SID) to Ringer's lactate (RL) for treating metabolic acidosis, hypothesizing the superiority of the H-SID solution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Forty-six dogs with metabolic acidosis from two veterinary hospitals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Prospective randomized multicenter study. Dogs were randomly assigned to receive either RL or H-SID at infusion rates of 4 or 10 mL/kg/h for 4 h, based on their volume status. H-SID was compounded with sodium (145 mmol/L), lactate (145 mmol/L), potassium (10 mmol/L), and aspartate (10 mmol/L) in sterile water for injection.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The H-SID group showed a significant increase in BE-ecf (mmol/L) at infusion rates of 4 mL/kg/h (<i>p</i> &lt; 0.001) and 10 mL/kg/h (<i>p</i> &lt; 0.001) when compared to the RL group. At the lower infusion rate, the median increase was 4.1 mmol/L (95% CI: 3.37, 6.71), whereas the RL group exhibited a variation of −0.1 (95% CI: −0.75, 2.2). At the higher infusion rate, the median increase was 11 mmol/L (95% CI: 8.16, 12.52) compared to the RL group variation of 1.3 (95% CI: 0.01, 2.96).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Clinical Importance</h3>\u0000 \u0000 <p>Our results indicate a significant alkalizing effect of the H-SID solution in dogs with non-lactic metabolic acidosis, demonstrating a superior effect compared to the RL solution without notable adverse effects.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143835872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Owner Personality and Other Owner-, Cat- and Treatment-Related Factors on the Perception of Quality of Life in Cats With Hyperthyroidism","authors":"Sofie Muthmann,&nbsp;Imogen Schofield,&nbsp;Martin Kersting,&nbsp;Fabienne Blunschi,&nbsp;Joana Léonie Tiefenbrunner,&nbsp;Natali Betina Bauer,&nbsp;Katarina Hazuchova","doi":"10.1111/jvim.70091","DOIUrl":"https://doi.org/10.1111/jvim.70091","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Assessment of quality-of-life (QoL) is becoming increasingly important in veterinary medicine. In human medicine, it is known that the assessor's personality might affect QoL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the impact of owner personality and other owner, cat, and treatment-related factors on the health-related QoL (HRQoL) of hyperthyroid cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Five hundred hyperthyroid cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective, cross-sectional, questionnaire-based study, conducted between April 2023 and February 2024. Owners completed the HyperthyroidismQoL-cat and the Big Five Inventory-2 to assess the cat's HRQoL and owner's five personality domains, respectively. Additional information about owner-, cat-, and treatment-related factors was collected. Univariable and multivariable linear regression modeling was used to assess associations between owner personality, other factors, and the cat's HRQoL. Significance was <i>p</i> &lt; 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In multivariable analysis, radioiodine treatment (RAIT; <i>p</i> = 0.001) and having a comorbidity (<i>p</i> ≤ 0.001) resulted in better HRQoL, whereas negative owner emotionality (<i>p</i> ≤ 0.001), having children ≤ 18 years of age (<i>p</i> = 0.04), treatment using a low iodine diet (LID; <i>p</i> = 0.023), no treatment (<i>p</i> = 0.03) and being hyperthyroid (<i>p</i> ≤ 0.001), hypothyroid (<i>p</i> = 0.004) or unknown thyroid status (<i>p</i> = 0.001) resulted in worse HRQoL.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion and Clinical Importance</h3>\u0000 \u0000 <p>When interpreting HRQoL data, the potential impact of the personality domain negative emotionality (tendency to experience anxiety, fear, negative emotions) should be considered. Based on HRQoL, RAIT is the treatment of choice, whereas LID or no treatment are the least favored options. These findings should be considered when counseling owners about their cats' hyperthyroidism and its management.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143830994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Evaluation of Hematological Ratios in Dogs With Nonassociative Immune-Mediated Hemolytic Anemia: 206 Cases","authors":"Antoine A. Duclos,&nbsp;Luke O'Sullivan,&nbsp;Ciara McPhedran,&nbsp;Samuel Hocker,&nbsp;Kevin Le Boedec,&nbsp;Shauna Blois,&nbsp;Benoît Cuq","doi":"10.1111/jvim.70101","DOIUrl":"https://doi.org/10.1111/jvim.70101","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The utility of hematological ratios in immune-mediated hemolytic anemia (IMHA) in dogs has seldom been investigated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Hypothesis</h3>\u0000 \u0000 <p>Hematological ratios are associated with disease severity and outcome in dogs with IMHA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Two hundred and six client-owned dogs with non-associative IMHA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Retrospective multicenter study. Medical records were reviewed to identify dogs with non-associative IMHA. The neutrophil-to-lymphocyte (NLR), neutrophil-to-monocyte (NMR), band neutrophil-to-segmented neutrophil (BNR), platelet-to-lymphocyte (PLR), monocyte-to-lymphocyte (MLR), neutrophil-to-platelet (NPR) and red blood cell distribution width-to-platelet (RDWPR) ratios were retrospectively calculated. Their association with hematological variables, number of blood transfusions, and survival at discharge, 1 month, and 6 months was evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 206 dogs included, 164 (80%, 95% confidence interval [CI]: 74–85), 144 (70%, 95% CI: 64–76), and 114 (55%; 95% CI: 48–62) were alive at discharge, one month, and six months, respectively. The hematological ratios were not associated with survival at any time point, regardless of treatment before referral. Only the RDWPR was associated with blood product requirement (odds ratio [OR], 0.70; 95% CI: 0.54–0.91; <i>p</i> &lt; 0.01). Dogs that had received glucocorticoids before referral had a higher 1-month mortality rate compared with glucocorticoid-naïve dogs (73% and 67%, respectively; OR, 2.2; 95% CI: 1.1–4.5; <i>p</i> = 0.03).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Clinical Importance</h3>\u0000 \u0000 <p>Hematological ratios had limited value in predicting outcome or disease severity in a large population of dogs with non-associative IMHA. Glucocorticoid treatment before referral was independently associated with decreased survival, likely reflecting selection bias toward dogs with more severe disease.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143831027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Seasonality of Serum Insulin Concentrations in Equids and the Association With Breed, Age, and Sex","authors":"Ana Lopes,&nbsp;Laura Huber,&nbsp;Andy E. Durham","doi":"10.1111/jvim.70089","DOIUrl":"https://doi.org/10.1111/jvim.70089","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Current laboratory reference values for serum insulin concentrations do not account for seasonal fluctuations and differences associated with breed, sex, and age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Hypothesis</h3>\u0000 \u0000 <p>We hypothesized that serum insulin concentrations would differ with the season, breed, sex, and age.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Laboratory records from 21 236 cases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Cases were included where basal serum insulin concentration (INS) or serum insulin concentration after administration of Karo light syrup (INS_pk) was measured, along with plasma glucose, breed, age, and sex. Multivariate analysis was used to investigate a seasonal effect on serum insulin concentrations, alongside the effect of breed, age, and sex.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Basal serum insulin concentration in winter was significantly higher than in the other seasons (<i>p</i> &lt; 0.001). Serum insulin concentration following administration of Karo light syrup in winter was significantly higher than in summer and fall (<i>p</i> &lt; 0.001). The breed effect was assessed in the 9 most prevalent breeds and the donkey. Shetland ponies had significantly higher INS and INS_pk than all breeds except Welsh ponies(<i>p</i> &lt; 0.01). Welsh ponies had significantly higher INS than all other breeds except Shetland ponies (<i>p</i> &lt; 0.01). Welsh ponies had significantly higher INS_pk than all breeds (all <i>p</i> &lt; 0.001), except Arabians, New Forest ponies, and Shetland ponies. Females had significantly higher INS than males (<i>p</i> &lt; 0.001) and there was a positive and significant association between age and INS (est = 0.02; SE = 0.002, <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Insulin concentrations are influenced by season, breed, age, and sex. This information is essential for better understanding and management of insulin dysregulation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143822219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective Estimation of the Prevalence of Thromboembolism in Dogs With Inflammatory Protein-Losing Enteropathy","authors":"Nene Oishi,&nbsp;Hiroshi Ohta,&nbsp;Masahiro Tamura,&nbsp;Kiwamu Hanazono,&nbsp;Kenjiro Miyoshi,&nbsp;Nozomu Yokoyama,&nbsp;Genya Shinbo","doi":"10.1111/jvim.70098","DOIUrl":"https://doi.org/10.1111/jvim.70098","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Inflammatory protein-losing enteropathy (iPLE) is thought to be associated with a hypercoagulable state and may predispose dogs to thromboembolism (TE). However, little information is available regarding the prevalence of TE in dogs with iPLE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Estimate the prevalence of TE in dogs with iPLE and collect clinical and clinicopathologic data from dogs with iPLE with and without TE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Twenty-two client-owned dogs with iPLE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Prospective, descriptive study. Dogs definitively diagnosed with iPLE based on standard diagnostic criteria and histopathology were recruited between January 2019 and February 2024. At the time of gastrointestinal endoscopic examination, dogs with iPLE underwent thoracic and abdominal computed tomography angiography to detect TE. Clinical (e.g., clinical severity, use of corticosteroids) and clinicopathologic (e.g., albumin concentration, coagulation parameters) data were collected from dogs with iPLE with and without TE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thromboembolism was found in 3/22 dogs (13.6%, 95% confidence interval: 2.9–34.9) with iPLE. The three dogs with iPLE and TE had thrombi in the left external iliac artery, pulmonary artery of the right caudal lobe, and main portal vein, respectively. The dogs with thrombi in the left external iliac artery or pulmonary artery did not show any clinical signs associated with TE, whereas the dog with portal vein thrombosis had transudative peritoneal effusion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion and Clinical Importance</h3>\u0000 \u0000 <p>We estimated the prevalence of TE in dogs with iPLE. In dogs with iPLE, TE could be underestimated because some affected dogs have subclinical TE.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143824636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of Brain Magnetic Resonance Imaging Lesions in Dogs Treated for Meningoencephalomyelitis of Unknown Origin Between Initial Diagnosis and Relapse","authors":"Carole Soulé,&nbsp;Laurent Blond,&nbsp;Robin Cavalerie,&nbsp;Stéphanie Piazza,&nbsp;Clément Baudin-Tréhiou","doi":"10.1111/jvim.70086","DOIUrl":"https://doi.org/10.1111/jvim.70086","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The response of meningoencephalitis of unknown origin (MUO) in dogs to immunosuppressive treatment is unpredictable, and relapses frequently occur.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Our aim was to describe the evolution of brain magnetic resonance imaging (MRI) lesions in dogs treated for MUO from diagnosis to relapse and to define the diagnostic and clinical value of repeat MRI at relapse.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Eighteen dogs treated for MUO that experienced relapse and underwent MRI both at disease onset and relapse.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Retrospective, descriptive, longitudinal, case series study. Dogs were identified from medical records between 2015 and 2024. The MR images were reviewed by radiologists for lesion number, location, size, pre- and post-contrast signal aspect, meningeal enhancement, mass effect, perilesional edema, and evidence of intracranial hypertension.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Median interval between MRIs was 259 days (range, 31–876 days). In dogs with relapse delay &lt; 157 days, lesion number tended to decrease. Residual lesions tended to enlarge and exhibit contrast enhancement and perilesional edema (suggesting an active pathologic process), but without development of new lesions. After 233 days, all dogs had developed new lesions. Half exhibited enlarged active residual lesions, whereas the others showed either remission or smaller inactive lesions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Before a clinical relapse at approximately 6 months, remission of the initial pathologic process and development of new lesions appear unlikely. Beyond this period, new lesions may occur with or without remission of the initial pathologic process, and repeat MRI is of high diagnostic and clinical value in detecting new lesions and characterizing the underlying pathologic process.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70086","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for “Risk Factors and Long-Term Outcomes in Horses After the 2021 Outbreak of Equine Herpesvirus 1 Myeloencephalopathy, Valencia, Spain”","authors":"","doi":"10.1111/jvim.70084","DOIUrl":"https://doi.org/10.1111/jvim.70084","url":null,"abstract":"<p>\u0000 <span>M. de la Cuesta-Torrado</span>, <span>A. V. Alvarez</span>, <span>I. Santiago-Llorente</span>, et al., “ <span>Risk Factors and Long-Term Outcomes in Horses After the 2021 Outbreak of Equine Herpesvirus 1 Myeloencephalopathy, Valencia, Spain</span>,” <i>Journal of Veterinary Internal Medicine</i> <span>39</span> (<span>2025</span>): e70040.\u0000 </p><p>In the above mentioned article, there is an error in the Abstract Results paragraph, last sentence. The sentence should be as follows.</p><p>“Rt was initially 4.2 and decreased to &lt; 1 within 2 weeks of the outbreak.”</p><p>Also, Reference 29 is incomplete. Reference 29 should be as follows.</p><p>“Robert Koch Institud, “Robert Koch Institud [Internet]. Epidemiologisches. Bulletin,” 2020. [cited 2024 Mar 10]. Available from: https://www.rki.de/DE/Aktuelles/Publikationen/Epidemiologisches-Bulletin/2020/17_20.pdf?__blob=publicationFile&amp;v=1. Accessed: 28 May 2021.”</p><p>We apologize for the errors.</p>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum for “Accuracy of the Freestyle Libre 3 Continuous Glucose Monitoring System in Hypo- and Euglycemic Cats”","authors":"","doi":"10.1111/jvim.70085","DOIUrl":"https://doi.org/10.1111/jvim.70085","url":null,"abstract":"<p>\u0000 <span>A. M. Tardo</span>, <span>C. Crews</span>, <span>J. Mott</span>, <span>L. T. Porter</span>, <span>C. Adin</span>, and <span>C. Gilor</span>, “ <span>Accuracy of the Freestyle Libre 3 Continuous Glucose Monitoring System in Hypo- and Euglycemic Cats</span>,” <i>Journal of Veterinary Internal Medicine</i> <span>39</span> (<span>2025</span>): e70048.\u0000 </p><p>In the above mentioned article, Reference 14 is incorrect. The correct Reference 14 should be as follows.</p><p>“A. S. Berg, C. D. Crews, C. Adin, et al., “Assessment of the FreeStyle Libre 2 interstitial glucose monitor in hypo- and euglycemic cats,” <i>J Vet Intern Med</i>. 2023: 37(5):1703–1709. https://doi:10.1111/jvim.16820.”</p><p>We apologize for this error.</p>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of a Novel Immunogenic Feline Erythrocyte Antigen (FEA 6) and Expression Patterns Between FEAs","authors":"Félix Bajon,&nbsp;Julie Arsenault,&nbsp;Marie Claude Blais","doi":"10.1111/jvim.70094","DOIUrl":"https://doi.org/10.1111/jvim.70094","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>After the identification of five novel feline erythrocyte antigens (FEAs) and evidence establishing FEA 1's immunogenicity, attempts to sensitize a cat to FEA 4 unexpectedly resulted in the production of alloantibodies directed against an unknown antigen, named FEA 6.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To estimate the prevalence of FEA 6 as a presumably new antigen, identify corresponding naturally occurring alloantibodies (NOAb), and investigate the associations between known FEAs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Two hundread and seven cats.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Prospective blood typing for FEAs 1–6 was conducted in Type A cats (<i>n</i> = 193), followed by serial crossmatching in groups of 3–7 cats to detect NOAb and identify their target FEA. Agreement between FEA 6 blood typing and other FEAs was assessed. Associations between FEAs were evaluated to identify expression patterns.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 193 Type A cats, 67% were FEA 6-positive. Agreement analyses were supportive of FEA 6 being distinct from FEAs 1–5. NOAb were detected in 11 cats (5.7%), none of which were anti-FEA 6. Only FEA 1-negative status was significantly associated with the presence of NOAb (OR = 6.6, 95% CI, 1.9–23.1; <i>p</i> &lt; 0.001). Significant associations were observed between the expressions of FEAs 1 and 4 (<i>χ</i>² = 25.7, <i>p</i> &lt; 0.001), and FEAs 3 and 5 (Fisher's exact test, <i>p</i> &lt; 0.001), respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Clinical Importance</h3>\u0000 \u0000 <p>The immunogenicity and prevalence of the newly discovered FEA 6 raise concerns regarding its clinical relevance and role in posttransfusion sensitization. FEA 1/FEA 4 and FEA 3/FEA 5 pairs might belong to distinct antigenic systems.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Utility of F-Waves in Paraplegic Dogs With Absent Pain Perception Secondary to Intervertebral Disc Extrusion","authors":"Go Togawa,&nbsp;Melissa J. Lewis,&nbsp;Stephen R. Were,&nbsp;R. Timothy Bentley,&nbsp;Stephanie A. Thomovsky","doi":"10.1111/jvim.70092","DOIUrl":"https://doi.org/10.1111/jvim.70092","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Approximately 50%–60% of paraplegic deep pain negative (DPN) dogs secondary to thoracolumbar intervertebral disc extrusion (TL-IVDE) recover ambulation after surgery. Mean F-wave duration has been associated with injury severity in TL-IVDE in dogs, but the relationship to outcome is unknown.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Evaluate the prognostic utility of F-waves in DPN dogs secondary to TL-IVDE treated surgically.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Thirty client-owned, acutely paraplegic DPN dogs secondary to TL-IVDE were managed surgically.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Multi-center prospective and observational study. F-waves were performed at baseline (within 24 h post-operatively), 2–4 weeks and 3 months post-operatively. Outcome was categorized as successful or unsuccessful, with success defined as independent ambulation at 3 months post-operatively. F-wave variables were compared between dogs with a successful or unsuccessful outcome and over time using generalized estimating equations. Receiver-operating characteristic curves were generated for baseline F-wave variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>F-waves were well-tolerated in all dogs. Of 30 enrolled dogs, 12 dogs had a successful outcome, 10 dogs were unsuccessful, and 8 dogs were removed from outcome analysis (3 progressive myelomalacia, 1 severe spinal shock, 2 technical error, and 2 unknown outcome). Baseline mean F-wave duration (displayed as median (range)) was longer in unsuccessful dogs (31.7 (11.4–60.8) ms) versus successful dogs (19.6 (10.8–27.3) ms), <i>p</i> = 0.003. Mean F-wave duration &gt; 28.5 ms was 70% sensitive (95% confidence interval (CI): 40%–100%) and 100% specific (95% CI: 100%–100%) in predicting an unsuccessful outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and Clinical Importance</h3>\u0000 \u0000 <p>F-waves performed shortly post-operatively could aid in predicting outcomes in DPN dogs secondary to TL-IVDE treated surgically.</p>\u0000 </section>\u0000 </div>","PeriodicalId":49958,"journal":{"name":"Journal of Veterinary Internal Medicine","volume":"39 3","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/jvim.70092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}