Journal of Voice最新文献

{"title":"World Voice Day 2025.","authors":"Robert T Sataloff","doi":"10.1016/j.jvoice.2025.02.011","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.011","url":null,"abstract":"","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From a Health and Safety Lens: Voice-Related Concerns of Sporting, Fitness, and Wellness Leaders.","authors":"Victoria Reynolds, Ashley FitzSimmons-Olsen, Noël Nocciolo, Dominic Reynolds","doi":"10.1016/j.jvoice.2025.02.006","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.006","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to survey conditions, behaviors, and beliefs surrounding occupational voice use in fitness professionals, including the exploration of workplace factors that could be modified following principles of risk mitigation.</p><p><strong>Methods: </strong>Individuals who instructed or led others in physical activity were eligible for this study. Recruitment was conducted through professional networks and social media. 69 participants responded to an anonymous online questionnaire consisting of items addressing demographics, type and frequency of fitness instruction, behavioral and environmental factors, symptoms of dysphonia, voice education, protective equipment, and level of concern regarding their voice. Responses were then included in statistical and thematic analyses.</p><p><strong>Results: </strong>Statistical analysis revealed no significant relationship between the presence of voice or throat symptoms and the presence of voice concerns in participants. 87.93% of respondents reported that they were not concerned about their voice; however, 72.7% of respondents reported experiencing a change in their voice, such as changes in pitch or vocal quality. Voice concerns were more likely to be noted in respondents who had participated in voice education. Thematic analysis identified global themes of a) knowledge, thoughts, and beliefs, and b) modifications to work, practices, behaviors, and conditions among the reasons for the lack of concern reported by participants. Furthermore, participants appeared to be largely aware of the potential for work-related voice issues to arise. However, whether or not they related these issues to their workplace presence and practices was less clear.</p><p><strong>Conclusion: </strong>Sporting, fitness, and wellness leaders experience a high rate of voice and throat symptoms, yet display relatively low levels of concern about their voices in the workplace. Further investigation is needed to explore methods for altering or supplementing vocal delivery in fitness instruction to increase vocoergonomics and decrease the risk of vocal damage within this population.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of Wavelet Analysis and Paraconsistent Feature Extraction in the Classification of Voice Pathologies.","authors":"Gabriel José Pellisser Dalalana, Rodrigo Capobianco Guido, Eduardo Sperle Honorato, Ivan Nunes da Silva","doi":"10.1016/j.jvoice.2025.01.021","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.01.021","url":null,"abstract":"<p><strong>Objectives: </strong>This study explores the application of wavelet analysis and paraconsistent logic for the classification of voice pathologies. The primary objective is to develop a methodology combining signal decomposition techniques and intelligent classification to distinguish between healthy and pathological voice samples.</p><p><strong>Methods: </strong>Voice signals from the Saarbruecken Voice Database were preprocessed and decomposed using the discrete-time wavelet packet transform across multiple levels. Features such as energy, entropy, and zero-crossing rate (ZCR) were extracted for classification using support vector machines. Additionally, a paraconsistent logic framework was implemented to handle uncertainty and class overlap, enhancing classification. Six wavelet families were analyzed, including Haar, Daubechies, Symlets, Coiflets, Beylkin, and Vaidyanathan, to identify the most suitable filters for each pathology.</p><p><strong>Results: </strong>The proposed method achieved high classification accuracy, surpassing several state-of-the-art approaches. The best-performing filters varied by pathology, with Sym32, Beylkin18, and Vaidyanathan24 excelling for dysphonia, Daub4, Daub12, Sym8, and Coif6 for Reinke's edema, and Haar, Sym32, and Coif6 for recurrent laryngeal nerve paralysis. Energy and ZCR proved particularly effective as features, while entropy exhibited limited performance in this context.</p><p><strong>Conclusions: </strong>The integration of wavelet-based signal analysis and paraconsistent logic offers a powerful approach for voice pathology classification. This methodology not only improves classification accuracy but also provides a computationally efficient framework suitable for clinical applications. Future work will focus on expanding datasets and developing real-time diagnostic tools.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143477017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MAGEA9 Expression in Vocal Fold Leukoplakia and Its Enhancement of Vocal Fold Leukoplakia Epithelial Cell Proliferation, Migration, and Invasion Through the NF-kB-MMP-2/9 Pathway.","authors":"Yong-Cai Liu, Chun-Hai Yu, Qin-Ying Wang, Jiang-Tao Zhong, Yang-Yang Bao, Zi-Ming Fu, Zhe Chen, Heng-Chao Chen, Zai-Zai Cao, Shui-Hong Zhou","doi":"10.1016/j.jvoice.2025.02.001","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.001","url":null,"abstract":"<p><strong>Purpose: </strong>The expression of MAGE-A9 in vocal fold leukoplakia (VFL) tissues and the mechanism underlying its role in the malignant transformation of VFL remain unclear. This study investigated the role of MAGE-A9 in the proliferation, migration, and invasion of VFL epithelial cells as well as the underlying regulatory mechanism.</p><p><strong>Methods: </strong>MAGE-A9 expression in VFL tissues was detected by immunohistochemistry. The CCK-8 assay, flow cytometry, and transwell assays were performed to determine the viability, cell cycle distribution and apoptosis, as well as migration and invasion, respectively, of primary cultured VFL epithelial cells. Ki67, cell cycle proteins, and proteins in the NF-kB-MMP-2/9 pathway were assessed by Western blotting.</p><p><strong>Results: </strong>MAGE-A9 expression was detected in 54.5% (18/33) of vocal fold polyps, 48.9% (44/90) of VFLs, and 84.8% (28/33) of laryngeal cancers. Significantly higher levels of expression were found in laryngeal cancer than in vocal fold polyps and VFL tissues (P < 0.001). The expression of MAGE-A9 tended to increase with the severity of VFL dysplasia. In VFL epithelial cells, the overexpression of MAGE-A9 significantly increased the viability, proliferation, migration, and invasion of the cells and reduced the level of apoptosis. The cell cycle effects of MAGE-A9 overexpression included an increased proportion of cells in the G2 and S phases and a decreased proportion of those in the G1 phase (P = 0.002), leading to an altered G1/S phase transition. MAGE-A9 overexpression also significantly increased p-IKBα, p-p65, MMP2, and MMP9 levels while decreasing those of IKBα. All of the effects of MAGE-A9 were inhibited by treating the cells with the IκBα phosphorylation inhibitor BAY 11-7082.</p><p><strong>Conclusion: </strong>MAGE-A9 expression tended to increase with the severity of dysplasia in VFL and was significantly higher in laryngeal cancer than in VFL. MAGE-A9 was shown to promote the proliferation, migration, and invasion of VFL epithelial cells via the NF-kB pathway and downstream targets such as MMP-2/9.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Cultural Adaptation and Validation of the Voice Handicap Index Into Estonian.","authors":"Aune Ello, Linda Sõber, Merje Viigand, Lagle Lehes","doi":"10.1016/j.jvoice.2025.01.017","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.01.017","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to validate the Voice Handicap Index (VHI-30) for the Estonian language and determine its psychometric properties.</p><p><strong>Study design: </strong>Cross-sectional and comparative study, combining subjective and objective methods.</p><p><strong>Methods: </strong>The objective data included voice recordings analyzed using the PRAAT software, which calculates the Acoustic Voice Quality Index (AVQI) to assess voice quality. Subjective data were gathered using the VHI-30 (Estonian version) (VHI-30-EST) to evaluate voice-related quality of life, and videolaryngostroboscopy was performed to examine vocal fold function in patients with dysphonia. Ten percent of the participants completed the VHI again after 2-4 weeks to assess test-retest reliability. The questionnaire's internal consistency, test-retest reliability, and clinical validity were evaluated.</p><p><strong>Results: </strong>The VHI-30-EST demonstrated excellent internal consistency, with a Cronbach's α of 0.977 in the test group and 0.893 in the control group. The test-retest reliability was strong, with an intraclass correlation coefficient of 0.968 for the total score. Validity analysis showed significant differences between the test and control groups for both VHI-30-EST and AVQI scores. Receiver operating characteristic curve analysis identified effective cut-off scores of 15.5 for VHI-30-EST and 2.8 for AVQI, with high sensitivity for both. Moderate correlations were found between VHI-30-EST scores and AVQI in the test group.</p><p><strong>Conclusions: </strong>The VHI-30-EST demonstrated strong internal consistency, excellent test-retest reliability, and solid clinical validity. Significant differences were observed between the test and control groups for both VHI-30-EST and AVQI scores, with moderate correlations between them. Effective cut-off scores were identified for both VHI-30-EST and AVQI, showing high sensitivity in distinguishing voice disorders. These results confirm the reliability and validity of VHI-30-EST in assessing voice-related quality of life in Estonian-speaking individuals.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of Auditory and Auditory-Visual Voice Quality Perception by Speech Language Pathologists and Ear, Nose, and Throat Specialists.","authors":"Michael Yeshayahu Finkelstein, Karen Banai, Oshrat Sella Weiss","doi":"10.1016/j.jvoice.2025.01.030","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.01.030","url":null,"abstract":"<p><p>Voice quality is evaluated by speech and language pathologists (SLPs) and ear, nose, and throat (ENT) specialists. They often use either auditory-perceptual assessment or laryngoscopy, which provides visualization of the larynx or both (auditory-visual assessment). This study compared the accuracy of auditory-perceptual voice quality assessment between auditory and auditory-visual assessments, and between SLPs and ENTs. Thirty SLPs and 30 ENTs listened to recordings that represent six voice qualities (high pitch, whisper, strained whisper, vocal fry, strained, and wet voice) realized with the sustained vowel /i/, presented auditorily and auditorily-visually (by laryngoscopy video). They characterized the voice qualities and rated the degree of dominance. The following factors predicted identification accuracy: condition (with/without visual information), voice quality, profession, and the interactions between condition and profession, and between voice quality and profession. SLPs identified whispers, strained whispers, and vocal fries more reliably than ENTs in both conditions. ENTs but not SLPs recognized auditory-visual presentations less accurately than auditory ones. This may be due to different emphases during voice evaluation: SLPs perform a primarily functional voice evaluation that requires sensitivity to various voice qualities, while evaluation by ENTs is mainly anatomical, focusing on laryngeal visualization. The results suggest that visual information from the larynx can impair the accuracy of voice quality perception.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Respiratory Muscle Training and Quadriceps Exercises on Voice, Respiratory Function in Community-Dwelling Older Adults.","authors":"Benjamas Prathanee, Netra Buakanok, Tawitree Pumnum, Nantiya Ooppanasak, Nichanun Panyaek","doi":"10.1016/j.jvoice.2024.12.006","DOIUrl":"https://doi.org/10.1016/j.jvoice.2024.12.006","url":null,"abstract":"<p><strong>Objective: </strong>This present study aimed to explore normative data and compare voice characteristics and respiratory function (Maximum counting duration: MCD peak expiratory flow rate: PEFR), Maximum inspiratory pressure: MIP), Maximum expiratory pressure: MEP), and quadriceps muscle strengthening before and after breathing with quadriceps exercises.</p><p><strong>Study design: </strong>A one-group quasi-experiment design.</p><p><strong>Setting: </strong>Community-dwelling healthy elderly in Health Promoting Hospital.</p><p><strong>Method: </strong>Thirty community-dwelling healthy elderly aged 60-70 years old were enrolled the study for normative data, and twenty-three were in complete study for comparison the outcomes. Participants were assessed voice characteristics via computer speech lab (CSL), respiratory function by peak flow meter, micro respiratory pressure meter, quadricep exercises by leg strength dynamometer and five times sit to stand. Program of breathing with quadriceps exercises were implemented twice a day in sitting, standing position, and walking for 7 weeks.</p><p><strong>Result: </strong>Voice characteristics were presented normative data, and comparison between preseven-week and postseven-week program of program intervention revealed significant increasing percentage of Maximum phonation time (MPT) or Tsam (time of sample) of /a/, /u/, /i/ ranged 39.30%-55.46%; MCD 40.99%, Maximum inspiration pressure 20.59%, MEP 16.22% and PEFR 84.21%, after program function.</p><p><strong>Conclusion: </strong>Program of breathing with quadriceps exercises could significantly increase MPT, MCD, MIP, MEP, and PEFR in community-dwelling healthy elderly within 7. These were guideline for prevention voice disorders and aspiration in older adult.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermography Analysis of Low-Level Laser Therapy Effect on the Swine Larynx.","authors":"Ana Carolina Nascimento Fernandes, Lucieny Martins Serra, Eduardo Magalhães da Silva, André Luiz Lopes Sampaio, Selma Aparecida Souza Kückelhaus","doi":"10.1016/j.jvoice.2025.02.003","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.003","url":null,"abstract":"<p><strong>Introduction: </strong>The vocal folds are intrinsically associated with the thyroarytenoid muscle. During phonation, microlesions and inflammations can occur due to excessive voice use, which can hinder the correct vibration of the mucosa and alter the voice quality. In addition to vocal hygiene and exercises to reduce phonatory effort, resources such as low-level laser therapy (LLLT) are being used in clinical settings. LLLT has been reported to have a biomodulatory action that can reduce pain and edema in the larynx by accelerating the inflammatory process through temperature variation. This study aimed to evaluate the temperature before and after the application of single or multiple doses of red (RL) and infrared (IRL) in the laryngeal tissues of swine.</p><p><strong>Materials and methods: </strong>This descriptive and comparative study was conducted at NuPMIA-FM/UnB and at Granja Miunça, located in the rural region of Brasília. The animals were randomly divided into 13 groups (n = 5) to evaluate the temperature of the larynx before and after LLLT treatment using photothermographic analysis.</p><p><strong>Results: </strong>The study showed the thermoregulatory effect of the laser as an acute response to 1 and 8 doses of LLLT in the swine larynx. One dose of RL increased the temperature of the young animals (P = 0.0318); multiple doses of IRL increased the laryngeal temperature of the adult group by 2.1%, with differences between the applications (paired t test, P = 0.0208). In the combination of lasers (RL + IRL), the laryngeal temperature in the group of adult animals increased by 0.9%, between the minimum and maximum temperature before application, and between the minimum and maximum temperature after LLLT. There was a difference between the mean temperatures before (P = 0.0010) and after the combined (RL + IRL) (P = 0.0025). Also, the results showed that young animals with no LLLT treatment had 12% higher temperature (35.7 ± 1.7 ºC) than adult animals with no treatment (31.2 ± 1.9).</p><p><strong>Interpretation: </strong>The results demonstrated that there is an increase and decrease in laryngeal temperature after different low-level laser therapy application protocols and at different doses. These findings could provide a clinical guide for the use of LLLT in humans.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Characteristics and Voice Handicap Index Assessment of Common Benign Vocal Fold Lesions: A Case-Control Study From a Referral Center.","authors":"Sina Azadnajafabad, Esmaeil Mohammadi, Sina Afzal, Hanye Sohrabi, Payman Dabirmoghaddam, Kayvan Aghazadeh","doi":"10.1016/j.jvoice.2025.01.019","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.01.019","url":null,"abstract":"<p><strong>Objectives: </strong>Benign vocal fold lesions (BVFL) significantly impact patients' quality of life. This study aimed to investigate the characteristics, risk factors, and voice-related impacts among BVFL patients compared with healthy controls and to propose new Voice Handicap Index (VHI) cutoffs for better diagnosis.</p><p><strong>Study design: </strong>Prospective case-control observational study.</p><p><strong>Methods: </strong>This study was conducted during 2022-2023. The case group included patients aged 18-65 years with dysphonia or related symptoms diagnosed with BVFL via videostroboscopy. The control group comprised individuals without voice disorders. Data collection included demographics, clinical history, and voice-related factors using the VHI questionnaire. Statistical analyses involved summary statistics and statistical tests for categorical and continuous variables, and logistic regression to identify predictors of BVFL. Receiver operating characteristic curve analysis was used to determine the optimal VHI cutoffs.</p><p><strong>Results: </strong>The study included 120 participants (60 BVFL patients, 60 controls), with overall median of age of 44 (Q1-Q3: 36.0, 52.0), and a male dominancy (61.7%). Polyps were the most common BVFL diagnosis (50.0%), followed by nodules (30.0%), cysts (15.0%), and granulomas (5.0%). BVFL patients had significantly higher total VHI scores (median 47, 35.8-59.0) compared with controls (median 11, Q1-Q3: 8.0-13.3). Multivariable logistic regression identified laryngopharyngeal reflux (LPR) (adjusted OR: 2.83, 95% CI: 1.20-6.89), severe talkativeness (adjusted OR: 3.99, 95% CI: 1.34-12.79), and high voice loudness (adjusted OR: 3.60, 95% CI: 1.11-12.77) as significant predictors. The optimal VHI cutoff to differentiate BVFL patients from controls was 17.5, with 96.7% sensitivity and 98.3% specificity.</p><p><strong>Conclusions: </strong>The study identifies key clinical and lifestyle factors associated with BVFL, emphasizing the importance of addressing modifiable risk factors like LPR, talkativeness, and voice loudness. The proposed VHI cutoffs improve diagnostic accuracy, facilitating better clinical assessment and management of BVFL patients, while considering it as complementary to clinical factors and assessments.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous Bed Side Evaluation of Dysphagia and Dysphonia in Patients Under Acute Treatment for Central Nervous System Disorders.","authors":"Yumi Nakagawa, Mami Kaneko, Yoichiro Sugiyama, Kumiko Nonaka, Shigeyuki Mukudai, Shigeru Hirano","doi":"10.1016/j.jvoice.2025.01.037","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.01.037","url":null,"abstract":"<p><strong>Objective: </strong>Hoarseness is often observed in patients with acute central nervous system (CNS) impairment. However, the vocal function is not routinely assessed. The purpose of this prospective study was to reveal the severity of dysphagia and dysphonia simultaneously during a bed side swallowing assessment in patients with CNS disorders.</p><p><strong>Study design: </strong>Prospective observational cohort study.</p><p><strong>Methods: </strong>The bed side evaluation of swallowing and vocal function was performed in 24 patients (aged 22-96 years; 14 male, 10 female) who were admitted to the Center for Neurology and Medical Science of out institute. They were suspected to have aspiration by a routine screening examination and required a bed side swallowing endoscopic assessment. The swallowing functions were evaluated by videoendoscopic swallowing test and Food Intake Level Scale (FILS). Vocal function was evaluated by bed side stroboscopic examinations with the measurement of vocal fold vibratory amplitude (VFVA) and Bowing Index (BI). Grade Roughness Breathiness Asthenia and Strain scale, aerodynamic and acoustic analyses were also completed. In addition, grip strength, tongue pressure measurements, geriatric nutritional risk index (GNRI), and the respiratory function tests were evaluated.</p><p><strong>Results: </strong>Swallowing and vocal function were impaired in all patients. An overall FILS average was level 4-6 that required alternative nutrition. Vocal fold atrophy was observed in 19 patients with reduced values in both VFVA and BI. Inspiratory function and muscle strength were decreased compared to the average of the healthy elderly, and the overall average of nutrition fell into the category of moderate nutritional impairment.</p><p><strong>Conclusions: </strong>The current study revealed that both swallowing and vocal function were impaired in the patients under acute treatment of CNS disorders. It was suggested that several factors can affect swallowing and vocal disorder in CNS disorder patients, including vocal fold atrophy, poor respiratory function, reduced muscle strength, and poor nutritional status, which should be kept in mind during the treatment or rehabilitation for CNS disorders.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}