Journal of Voice最新文献

{"title":"Blue Light Laser in Laryngology: Emerging Practice Patterns and Treatment Paradigms in North America.","authors":"Stephanie E Teng, Lauren E Schlegel, Alexa J Kacin, Pavan S Mallur","doi":"10.1016/j.jvoice.2025.06.037","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.06.037","url":null,"abstract":"<p><strong>Objectives: </strong>The 445 nm blue light laser (BL) was introduced to provide photoangiolytic, ablative, and cutting capabilities for laryngological applications. Since U.S. Food and Drug Administration approval in 2021, limited data exist examining usage in the United States. Here we characterize early practice patterns of BL use by laryngologists in North America.</p><p><strong>Methods: </strong>A fifteen-item survey queried for pathologies treated with BL and associated laser parameters, fiber-to-tissue modality, and intended tissue effect. Respondents were asked to categorize common end-tissue effects as perceived strengths or weaknesses of BL.</p><p><strong>Results: </strong>There were 21 respondents utilizing BL in clinical practice, with 22 total respondents out of 48 recipients identified as owning/renting the laser. The majority practiced in an academic setting (n = 17), both in office (n = 15) and operating room (n = 19) locations. Laser settings for wattage, pulse width, and pulse pause varied widely. The laser was most frequently used for papilloma (n = 17), leukoplakia (n = 15), and Reinke's edema (n = 11). Treatment paradigms most often involved both contact/non-contact mode (n = 15) for tissue ablation (n = 14) with papilloma, non-contact (n = 8) for tissue ablation (n = 10) with leukoplakia, and non-contact (n = 9) for epithelial blanching (n = 7) with Reinke's edema. The majority of respondents found tissue ablation (n = 15) and angiolysis (n = 11) to be strengths and cutting capability (n = 12) to be a weakness.</p><p><strong>Conclusions: </strong>Survey for BL use in North American laryngology practice reveals pathology-specific treatment paradigms. The most common usage was for papilloma, leukoplakia, and Reinke's edema, consistent with the perceived strength in ablative and angiolytic properties. Laser parameters varied widely and is one avenue for future systematic investigation. However, when attempting to using the laser in a cutting modality, there was a trend towards using higher wattages (>6 W) and in a \"contact\" modality.</p><p><strong>Level of evidence: 3: </strong></p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Anxiety, Depression, and Self-Perceived Hoarseness: A Systematic Review of the Literature.","authors":"Abdul-Latif Hamdan, Christophe Abi Zeid Daou, Zeina Maria Semaan, Lana Ghzayel, Randa Al Barazi, Jerome R Lechien","doi":"10.1016/j.jvoice.2025.06.007","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.06.007","url":null,"abstract":"<p><strong>Objective: </strong>This review aims to evaluate the correlation between anxiety, depression, and self-perceived hoarseness in patients with dysphonia.</p><p><strong>Study design: </strong>Systematic review.</p><p><strong>Methods: </strong>A systematic search of Medline, PubMed, and Cochrane databases was performed. Studies focusing on the relationship between anxiety, depression, and self-reported voice measures in dysphonic patients were included, while duplicates, incomplete data, animal studies, and reviews were excluded, following Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines.</p><p><strong>Results: </strong>Of the 416 articles identified, 24 papers were reviewed. Eleven studies met the inclusion criteria and were included. Most studies used the Voice Handicap Index (VHI), VHI-10, and the Hospital Anxiety and Depression Scale as assessment tools. The studies demonstrated a positive correlation of varying degrees between anxiety, depression, and self-perceived hoarseness, except for patients with spasmodic dysphonia in one study.</p><p><strong>Conclusion: </strong>This review highlights significant positive correlation between anxiety, depression, and self-perceived hoarseness, emphasizing the importance of early identification and treatment of mental health issues to improve patient outcomes.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association Between Cervical Spine Alignment and Voice Symptoms in Patients With Voice Disorders: A Prospective Cohort Study.","authors":"Su Il Kim, In-Seok Son, Je Ho Bang, Young-Gyu Eun, Su Jin Kim, XiongJie Li, Sung-Min Kim, Yong-Chan Kim, Young Chan Lee","doi":"10.1016/j.jvoice.2025.07.001","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.07.001","url":null,"abstract":"<p><strong>Objectives: </strong>Although neck posture can influence voice and phonation by affecting laryngeal positioning, muscle tension, and respiratory dynamics, there is a lack of studies evaluating cervical spine status in patients with voice disorders. This study aimed to assess the association between cervical spine alignment, measured using radiographic parameters, and voice assessment in patients with voice disorders.</p><p><strong>Methods: </strong>Patients with voice disorders who visited an otolaryngology clinic were prospectively enrolled. Patients were divided into hyperfunctional and nonhyperfunctional voice disorder groups. Voice quality was evaluated using the Voice Handicap Index-10 (VHI-10), and Grade, Roughness, Breathiness, Asthenia, Strain (GRBAS) scale, acoustic analysis, and aerodynamic study. Cervical spine alignment was evaluated via lateral cervical radiography, measuring C2-7 lordosis, C2-7 sagittal vertical axis (SVA), and chin-brow vertical angle. Correlations between the cervical spine alignment parameters and voice assessments within each group were analyzed using Spearman's rank correlation.</p><p><strong>Results: </strong>Seventy patients with voice disorders were enrolled in this study, 35 patients with hyperfunctional voice disorders and 35 patients with nonhyperfunctional voice disorders. The hyperfunctional group showed significantly less C2-7 lordosis than the nonhyperfunctional group (P = 0.011), indicating a more forward-flexed neck posture. In the hyperfunctional group, C2-7 lordosis showed significant positive correlation with the total VHI-10 score (P = 0.047), and with physical (P17), functional (F22), and emotional (E23) VHI items. Breathiness and Strain components of the GRBAS scale also showed significant correlation with C2-7 lordosis (P = 0.040 and 0.026, respectively). No meaningful correlations were found in the nonhyperfunctional group.</p><p><strong>Conclusions: </strong>C2-7 lordosis, a measure of cervical alignment, was significantly associated with voice symptoms in patients with hyperfunctional voice disorders. These findings suggest that cervical posture may influence voice quality and should be considered in the assessment and management of voice disorders, particularly in patients with hyperfunctional patterns.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection and Patterns of Pharyngeal Reflux Events With Two Ambulatory Pharyngeal Impedance-pH Monitoring Systems: A Comparative Study.","authors":"Jérôme R Lechien","doi":"10.1016/j.jvoice.2025.07.003","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.07.003","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the detection and patterns of pharyngeal reflux events in laryngopharyngeal reflux disease (LPRD) patients according to the type of ambulatory hypopharyngeal-esophageal multichannel intraluminal impedance-pH monitoring (HEMII-pH) system used and assessed whether potential HEMII-pH differences impact the pretreatment to post treatment findings.</p><p><strong>Methods: </strong>Patients with laryngopharyngeal symptoms and findings and an objective LPRD diagnosis were prospectively recruited from the European Reflux Clinic from January 2017 to December 2024. The objective diagnosis was supported by two different HEMII-pH systems (Medtronic and Sandhill). The profiles of LPRD on the objective testing devices (acid, weakly acid, and alkaline LPRD) of patients from the same clinic were prospectively compared. Reflux symptom scores (RSS) and reflux sign assessment (RSA) were used to document prepersonalized to postpersonalized treatment symptoms and findings. A study of the correlation between HEMII-pH features, symptoms, and signs was conducted.</p><p><strong>Results: </strong>The study included gender- and age-matched 101 patients with a Sandhill HEMII-pH and 102 patients with a Medtronic HEMII-pH. Both systems detected distal esophageal reflux events similarly, but Medtronic detected significantly more pharyngeal reflux events. The Sandhill group showed higher proportions of acid and weakly acid LPRD, while Medtronic patients predominantly had alkaline reflux. Patients of both groups demonstrated significant RSS reduction after treatment (P = 0.001), with a trend toward higher response rates in the Sandhill group (P = 0.067). Symptom scores were better correlated to the Sandhill pharyngeal reflux event features than the Medtronic one.</p><p><strong>Conclusion: </strong>The patterns of LPRD can substantially vary according to the type and catheter configuration of ambulatory HEMII-pH systems used. The differences between HEMII-pH devices support the need for revising consensus statements defining the thresholds of pharyngeal reflux events for confirming the LPRD diagnosis.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Development of an Anaerobic Vocal Fitness Task: Exploring the Relationship Between Lower Body Anaerobic Power and Vocal Function Measures.","authors":"Mariah E Morton-Jones, Mary J Sandage","doi":"10.1016/j.jvoice.2025.06.029","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.06.029","url":null,"abstract":"<p><strong>Purpose: </strong>This exploratory study aimed to determine the physiological correlation between lower body anaerobic power and vocal anaerobic power via vocal function measures derived from the vocal capacity anaerobic task (VCAT⁶⁰).</p><p><strong>Methods: </strong>Forty-four individuals were prospectively consented for participation (age 19-40) and completed the following measures: The VCAT⁶⁰, body composition analysis, aerodynamic assessment to determine forced vital capacity (FVC), and the Wingate Test, the most recognized anaerobic fitness assessment in exercise science.</p><p><strong>Results: </strong>Linear regression identified lower-body anaerobic power was a predictor of VCAT number of breaths (β = -0.004, P = 0.03) with a moderate effect size (R = 0.31). Spearman's correlation analysis revealed a positive linear relationship between a faster VCAT rate per second (rps) and higher mean lower-body anaerobic power (ρ(rho) = 0.34, P = 0.02). Linear regression identified lower-body anaerobic power as a significant predictor of VCAT rps (β = 0.05, P =< 0.001). The interaction of FVC and mean lower body anaerobic power suggests a moderating relationship (β = -0.0026, P = 0.016), in which the effect of mean anaerobic power on VCAT rps was dependent on FVC.</p><p><strong>Conclusions: </strong>This interdisciplinary study established preliminary evidence of validity for the VCAT⁶⁰, supporting the task as a physiologically sound and potentially useful anaerobic vocal fitness task to assess human anaerobic vocal muscle power in vivo.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Role of Adding Platelet-Rich Plasma to Autologous Fat Injection for Unilateral Vocal Fold Immobility: A Comparative Study.","authors":"Mohamed Fawaz, Islam Mohamed Hassan, Amr Roshdy Elbadrawy, Heba Ashour Mostafa, Ramez Reda, Ahmed Ali Abdelmonem","doi":"10.1016/j.jvoice.2025.06.038","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.06.038","url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed the efficacy and safety of vocal fold injection using autologous fat combined with platelet-rich plasma (PRP) compared with autologous fat alone in patients with unilateral vocal fold immobility (UVFI).</p><p><strong>Study design: </strong>A randomized controlled trial included 50 patients with dysphonia due to UVFI. Group A (25 patients) received an injection of autologous fat combined with PRP, while Group B (25 patients) received autologous fat only.</p><p><strong>Methods: </strong>Patients were evaluated using the modified GRBAS scale, telescopic laryngeal examination, the Arabic version of the Voice Handicap Index (VHI), computerized speech lab (CSL), and maximum phonation time (MPT). Assessments were conducted preinjection and at 1 and 12 months postinjection.</p><p><strong>Results: </strong>Group A showed significantly better outcomes in dysphonia grade, breathiness, and glottal gap at 1 month, but differences diminished by 12 months. Both groups improved similarly over time in jitter, shimmer, noise-to-harmonic ratio (NHR), MPT, and VHI, with no significant between-group differences. No postoperative complications were observed in either group, and none required reinjection 12 months after injection.</p><p><strong>Conclusion: </strong>Injection laryngoplasty using a combination of autologous fat and PRP is a safe and effective method for managing UVFI. While early subjective voice improvement was noted at 1 month in the PRP group, these differences were not sustained at 12 months. Thus, the addition of PRP to fat injection may provide transient early benefits but does not demonstrate clinically significant long-term superiority. Further studies with extended follow-up and more advanced instrumental assessment tools are still recommended for better management of UVFI.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anthropological Unfoldings of the Human Voice: The Formation of Humanity Through Voice.","authors":"Rubens Costa Güths","doi":"10.1016/j.jvoice.2025.06.026","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.06.026","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to describe six stages in which the voice plays a central role in the cultural and anthropological formation of humankind. These stages are referred to in this study as the Stages of Liberation of the Human Voice.</p><p><strong>Methods: </strong>Using a bibliographic approach, the history of the human voice is examined as a phenomenon rather than as an object of study within a specific field such as medicine or the arts.</p><p><strong>Results: </strong>The study first introduces four earlier stages, termed the Stages of Human Voice Imprisonment (SHVI). These stages encompass various historical events that have shaped human culture and, in some way, have directly or indirectly influenced vocal production-whether in theoretical, practical, or both forms. However, these stages should not be viewed as negative developments in the evolution of voice studies, but rather as necessary processes. Following this, the six Stages of Liberation of the Human Voice (SHVL) are presented. These stages represent the emancipation from implicit or explicit pre established premises concerning the phenomenon of voice and its various manifestations-such as speech, singing, poetry, ventriloquism, and vocal therapy. This liberation occurs in relation to constraints imposed by societal norms, the available knowledge and technology of a given historical period, prevailing beliefs about vocal production and its applications, and, in some cases, the inherent organic nature of the voice itself.</p><p><strong>Final considerations: </strong>Finally, the study concludes with a discussion on the significance of both the SHVI and the (SHVL) in contemporary vocal sciences, particularly in addressing the fundamental question: What is voice?</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Virtual Reality as a Tool in Gender-Affirming Voice Training: A Pilot Study.","authors":"Clara Leyns, Lien Bosschem, Tine Papeleu, Lode Sabbe, Gareth Walkom, Evelien D'haeseleer","doi":"10.1016/j.jvoice.2025.06.034","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.06.034","url":null,"abstract":"<p><strong>Objectives: </strong>The pilot study aimed to explore the potential of virtual reality (VR) speaking situations in generalizing elevated pitch to spontaneous speech and reducing speaking anxiety in trans women, as part of a voice feminization training program.</p><p><strong>Study design: </strong>A randomized controlled trial design was used, with an experimental group exposed to VR training (VRT) and a control group receiving traditional training without VR (TT).</p><p><strong>Methods: </strong>Eleven trans women were included, of which five were randomly assigned to the control group and six to the experimental group. All participants received four weekly 30-minute one-on-one training sessions. A Meta Quest 2 VR headset was used, in combination with the Therapy withVR web app. Outcome measures before and after training included the Trans Woman Voice Questionnaire (TWVQ), Willingness to Communicate (WTC), and median fundamental frequency (f_o) during reading and spontaneous speech. Descriptive analyses and figures were conducted in RStudio.</p><p><strong>Results: </strong>The TWVQ total scores showed a slight decrease for both groups, indicating minimal improvement in voice-related quality of life. In the VRT group, WTC scores increased across contexts, particularly in interactions with strangers and public speaking, while TT scores remained stable. For f_o, both groups demonstrated increased pitch. However, individual results show high variability between participants across the questionnaires.</p><p><strong>Conclusions: </strong>This pilot study suggests that VRT might potentially increase pitch and WTC among trans women, particularly in interactions with strangers. However, improvements in voice-related quality of life were modest. Larger, mixed-methods, and long-term studies are needed to better understand VR's potential as a supportive tool for gender-affirming voice training in the transgender and gender diverse population.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teachers' Self-Perception of Voice Before and After a Voice Awareness Program.","authors":"Gabriella Lucena Feitosa Rufino, Eduardo Lucas de Sousa Enéas, Bárbara Tayná Santos Eugênio da Silva Dantas, Maurícia Sousa Bernardo, Gleicy Nieskier Souza Ventura E Alencar, Marylia Albuquerque Andrade Ramos, Maria Fabiana Bonfim de Lima-Silva","doi":"10.1016/j.jvoice.2025.05.019","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.05.019","url":null,"abstract":"<p><strong>Purpose: </strong>To assess teachers' voice self-perception before and after participating in a voice awareness program.</p><p><strong>Material and methods: </strong>This interventional, descriptive, quantitative study, approved by the Human Research Ethics Committee under CAAE: 10719513.5.0000.5188, included 33 elementary and middle school teachers of both sexes from municipal schools in northeastern Brazil. The intervention had three stages, applying the Vocal Health and Hygiene Questionnaire (VHHQ) and the Voice-Related Quality-of-Life (V-RQOL) in the first one; conducting four vocal health workshops with theoretical and practical content in the second; and reapplying the VHHQ and V-RQOL in the third stage to compare results before and after the intervention.</p><p><strong>Results: </strong>Most participants were females, whose mean age neared the end of the vocal efficiency period. The protocols indicated that the voice awareness program positively impacted the study participants, with better voice perception and greater knowledge about factors harmful to vocal health.</p><p><strong>Conclusions: </strong>The research demonstrated the importance of informative programs on vocal health by exchanging knowledge, improving voice-related quality of life, and preventing vocal disorders.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144660916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a Python-Based Graphical User Interface for Calculation of Relative Fundamental Frequency.","authors":"Mara R Kapsner-Smith, Aideen Gill, Abigail Muzila, Tamara Polyakova, Austeja Rubeski, Joshua Kline, Cara E Stepp, Jenny Vojtech","doi":"10.1016/j.jvoice.2025.06.031","DOIUrl":"10.1016/j.jvoice.2025.06.031","url":null,"abstract":"<p><strong>Objectives: </strong>The purpose of this study was to validate PyRFF, a semi-automated software for calculating relative fundamental frequency (RFF). PyRFF was developed in Python, a widely used open source programming language, making it freely accessible and broadly applicable for researchers and clinicians. By providing an accessible tool for RFF extraction, PyRFF has the potential to facilitate wider adoption of RFF measures in both research and clinical settings.</p><p><strong>Study design: </strong>Validation study.</p><p><strong>Methods: </strong>To assess the accuracy of PyRFF, RFF measures were extracted using both PyRFF and a previously validated, semi-automated algorithm implemented in MATLAB. The outputs from the two programs were then compared using statistical measures of error, including root mean square error (RMSE) and mean bias error (MBE).</p><p><strong>Results: </strong>The results demonstrated near-identical outputs between PyRFF and the MATLAB-based algorithm. RMSE and MBE values were close to zero for all comparisons, indicating minimal discrepancy between the two methods.</p><p><strong>Conclusions: </strong>PyRFF offers a valid, freely available software platform for extracting RFF measures, ensuring accessibility for a broad user base of researchers, clinicians, and students. The availability of free, user-friendly software is essential for advancing research and clinical application of RFF in voice assessment. By providing an alternative to MATLAB-based methods, PyRFF lowers financial and technical barriers, promoting further exploration of RFF as a potential tool in voice disorder assessment and treatment.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144668829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}