LaeknabladidPub Date : 2023-09-01DOI: 10.17992/lbl.2023.09.757
Inga Thorsdottir, Birna Thorisdottir, Alfons Ramel, Thorhallur Halldorsson
{"title":"[Evidence and lifestyle - New nordic recommendations about nutrition and diet - emphasis on sustainability].","authors":"Inga Thorsdottir, Birna Thorisdottir, Alfons Ramel, Thorhallur Halldorsson","doi":"10.17992/lbl.2023.09.757","DOIUrl":"https://doi.org/10.17992/lbl.2023.09.757","url":null,"abstract":"Evaluation of research as basis for recommendations about lifestyle is discussed and especially recommendations about nutrition. Nordic recommendations on nutrients and diet with emphasis on sustainability are published 2023. Randomized trials, the strongest background for evidence based knowledge, are sometimes not possible to use when studying the influence of lifestyle on health. A tool applied in the Nordic recommendations 2023 evaluates the strength of relation between exposures (nutrients and food groups) and outcomes (health and environment), where research methods are observed and an organized quality control applied. The Interngovernmental Panel on Climate Change (IPCC) estimates the share of food systems in global anthropogenic GHG emissions is 31% (23%-42%). Nations now work on cutting GHG emissions from food systems by strengthening food based dietary guidelines and including sustainability, which benefits both health and environment. The recommendations about nutrients 2023 use harmonized methods and new data on body size in the Nordics. The food based dietary guidelines 2023 meet people's requirements for nutrients and are healthy for the environment. Physicians and other health professions will have the possibility to stimulate people´s interest to adhere to the recommendations about nutrition and diet built on a stronger and broader basis than before.","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 9","pages":"395-399"},"PeriodicalIF":0.4,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10483858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2023-09-01DOI: 10.17992/lbl.2023.09.756
Armey Valdemarsdottir, Anna Bryndis Blondal, Hjalti Kristinsson
{"title":"[Unlicensed drugs in Iceland in the years 2020 and 2021 with comparison to Sweden in 2020].","authors":"Armey Valdemarsdottir, Anna Bryndis Blondal, Hjalti Kristinsson","doi":"10.17992/lbl.2023.09.756","DOIUrl":"https://doi.org/10.17992/lbl.2023.09.756","url":null,"abstract":"<p><strong>Introduction: </strong>Prescriptions of unlicensed drugs along with public discussion have increased in recent years. The cause of this increase is unclear.</p><p><strong>Material and methods: </strong>This is a retrospective descriptive study of applications of unlicensed drugs in Iceland in the years 2020 and 2021, as well as applications in Sweden for the year 2020. Information was collected on unlicensed prescription applications, registered drugs and stock-out time. Information was analyzed and categorized to describe the scope of unlicensed prescriptions in the two countries during the study time.</p><p><strong>Results: </strong>In Iceland, 49.161 applications were approved in 2020 and 46.581 in 2021. The most common reason for using unlicensed products was that no registered drug was on the market with the same ATC-number (Anatomical Therapeutic Chemical code) and formulation. Shortage of drug was the reason for unlicensed prescription in 8.8% of cases in 2020 and 7.6% in 2021. The list of the 50 most prescribed drugs included the same drugs in 70% of the cases in both years. The five most prescribed drugs were the same in both years. In Sweden, 38.458 applications were approved in 2020. Of the most prescribed unlicensed drug, 46% were as no registered drug with same ATC-number and dosage form was marketed.</p><p><strong>Conclusion: </strong>Many unlicensed drugs, prescribed in Iceland, are the same year after year. Only a small part of the applications approved were due to shortage of drug. The use of drugs without marketing license in Iceland in 2020 was higher than in Sweden when adjusted for the size of the market and population. Getting the five most prescribed unlicensed drugs licensed in Iceland could reduce largely, the total of prescription of unlicensed drugs in Iceland.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 9","pages":"387-394"},"PeriodicalIF":0.4,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10483855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2023-09-01DOI: 10.17992/lbl.2023.09.758
Elin Ola Klemenzdottir, Arna Yr Karelsdottir, Valtyr Stefansson Thors
{"title":"[The many faces of Group A Streptococcal infections, case-series of invasive infections in children in Iceland].","authors":"Elin Ola Klemenzdottir, Arna Yr Karelsdottir, Valtyr Stefansson Thors","doi":"10.17992/lbl.2023.09.758","DOIUrl":"https://doi.org/10.17992/lbl.2023.09.758","url":null,"abstract":"<p><p>In recent months the incedence of invasive group A streptococcal infections (Streptococcus pyogenes) has increased worldwide. In the Children's Hospital Iceland 20 such cases were admitted during a four month period, until which time the avarage was one or two children admitted with an invasive GAS infection per year. To demonstrate the variability in the presentation of these invasive infections four cases were chosen for discussion in this case-series. Empyema with toxic shock syndrome, meningitis, orbital abscess and fascitis of the leg are reviewed.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 9","pages":"400-405"},"PeriodicalIF":0.4,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10483864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2023-07-01DOI: 10.17992/lbl.2023.0708.750
Gudjon Kristjansson
{"title":"[To cause no harm. Use and misuse of proton pump inhibitors].","authors":"Gudjon Kristjansson","doi":"10.17992/lbl.2023.0708.750","DOIUrl":"https://doi.org/10.17992/lbl.2023.0708.750","url":null,"abstract":"","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 708","pages":"329"},"PeriodicalIF":0.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Methylphenidate-induced psychosis in a young adult with newly diagnosed ADHD: A case report].","authors":"Ragna Kristin Gudbrandsdottir, Engilbert Sigurdsson, Oddur Ingimarsson","doi":"10.17992/lbl.2023.0708.753","DOIUrl":"https://doi.org/10.17992/lbl.2023.0708.753","url":null,"abstract":"<p><p>In view of the ongoing rise of ADHD prescriptions among adults in Iceland, it is important that doctors are aware that psychosis is a rare but at times a serious adverse reaction to such treatment. In 2022 5% of adults were prescribed medication to treat ADHD in Iceland. In this case report we present a case of methylphenidate-induced psychosis in a young man with no previous history of psychotic episodes who required admission to the psychiatric intensive care unit.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 708","pages":"346-349"},"PeriodicalIF":0.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2023-07-01DOI: 10.17992/lbl.2023.0708.749
Steindor Ellertsson
{"title":"[How can Artificial Intelligence be of use in the Healthcare System?]","authors":"Steindor Ellertsson","doi":"10.17992/lbl.2023.0708.749","DOIUrl":"https://doi.org/10.17992/lbl.2023.0708.749","url":null,"abstract":"","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 708","pages":"327"},"PeriodicalIF":0.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9696321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
LaeknabladidPub Date : 2023-07-01DOI: 10.17992/lbl.2023.0708.751
Karen Sol Saevarsdottir, Emma M Swift, Kristjana Einarsdottir, Johanna Gunnarsdottir
{"title":"[Postpartum hemorrhage in singleton births in Iceland 2013 - 2018, incidence proportion and risk factors].","authors":"Karen Sol Saevarsdottir, Emma M Swift, Kristjana Einarsdottir, Johanna Gunnarsdottir","doi":"10.17992/lbl.2023.0708.751","DOIUrl":"https://doi.org/10.17992/lbl.2023.0708.751","url":null,"abstract":"<p><strong>Introduction: </strong>Many countries have reported an increased incidence proportion of postpartum hemorrhage (PPH). The proportion might also have increased at the National University Hospital of Iceland, based on the registration of the ICD-10 code O72. This study aimed to assess the incidence proportion and risk factors for ≥1000 ml PPH in singleton births in Iceland 2013-2018.</p><p><strong>Methods: </strong>This population-based cohort study included data from the Icelandic Birth register on 21.110 singleton births in 2013-2018. Incidence proportion of PPH was assessed based on three definitions: PPH >500 ml, PPH ≥1000 ml, and O72. Binomial regression was used to assess both the change in the proportion of ≥1000 ml PPH over time, stratified by maternal BMI, and risk factors for ≥1000 ml PPH.</p><p><strong>Results: </strong>There was an inconsistency in the proportion of PPH when defined by blood loss >500 ml and O72. In obese women, PPH ≥1000 ml was more than twice as likely in those delivering in 2018 compared with 2013 (OR 2.23; CI 1.35-3.81). The strongest risk factors were emergency cesarean (OR 2.68; CI 2.22-3.22) and instrumental delivery (OR 2.18; CI 1.80-2.64), but macrosomia, primiparity and BMI ≥30 were also independent risk factors.</p><p><strong>Conclusion: </strong>The incidence proportion of ≥1000 ml PPH has increased among obese women. The detrimental health effects of obesity and the increased prevalence of interventions among these women could explain these results. It is necessary to use registered blood loss in milliliters in the Icelandic Birth Register because of the under-registration of the diagnostic code O72.</p>","PeriodicalId":49924,"journal":{"name":"Laeknabladid","volume":"109 708","pages":"331-337"},"PeriodicalIF":0.4,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9689668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}