[Perioperative stroke after aortic valve replacement for aortic stenosis - incidence, risk factors and short-term outcome].

IF 0.4 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Elin Metta Jensen, Katrin Juniana Larusdottir, Erla Liu Ting Gunnarsdottir, Sunna Lu Xi Gunnarsdottir, Anders Jeppsson, Tomas Gudbjartsson
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引用次数: 0

Abstract

Introduction: One of the most serious complications of surgical aortic valve replacement (SAVR) is stroke that can result in increased rates of complications, morbidity and mortality postoperatively. The aim of this study was to investigate incidence, risk factors and short-term outcome in a well defined cohort of SAVR-patients.

Materials and method: A retrospective study on 740 consecutive aortic stenosis patients who underwent SAVR in Iceland 2002-2019. Patients with stroke were compared with non-stroke patients; including preoperative risk factors of cardiovascular disease, echocardiogram-results, rate of early postoperative complications other than stroke and 30 day mortality.

Results: Mean age was 71 yrs (34% females) with 57% of the patients receiving stented bioprosthesis, 31% a stentless Freestyle®-valve and 12% a mechanical valve. Mean EuroSCORE-II was 3.6, with a maximum preop-gradient of 70 mmHg and an estimated valvular area of 0.73 cm2. Thirteen (1.8%) patients were diagnosed with stroke where hemiplegia (n=9), loss of consciousness (n=3) and/or aphasia (n=4) were the most common presenting symptoms. In 70% of cases the neurological symptoms resolved or disappeared in the first weeks and months after surgery. Only one patient out of 13 died within 30-days (7.7%). Stroke-patients had significantly lower BMI than non-stroke patients, but other risk factors of cardiovascular diseases, intraoperative factors or the rate of other severe postoperative complications than stroke were similar between groups. Total length of stay was 14 days vs. 10 days median, including 2 vs. 1 days in the ICU, in the stroke and non-stroke-groups, respectively.

Conclusions: The rate of stroke after SAVR was low (1.8%) and in line with other similar studies. Although a severe complication, most patients with perioperative stroke survived 30 days postoperatively and in majority of cases neurological symptoms recovered.

[主动脉瓣狭窄主动脉瓣置换术后围手术期中风--发生率、风险因素和短期疗效]。
导言:手术主动脉瓣置换术(SAVR)最严重的并发症之一是中风,可导致术后并发症、发病率和死亡率增加。本研究旨在调查一组明确定义的 SAVR 患者的发病率、风险因素和短期疗效:对 2002-2019 年在冰岛接受 SAVR 的 740 名连续主动脉瓣狭窄患者进行回顾性研究。将中风患者与非中风患者进行比较,包括术前心血管疾病风险因素、超声心动图结果、除中风外的术后早期并发症发生率和 30 天死亡率:平均年龄为71岁(34%为女性),57%的患者接受了支架生物瓣膜,31%接受了无支架Freestyle®瓣膜,12%接受了机械瓣膜。EuroSCORE-II平均值为3.6,术前最大坡度为70毫米汞柱,估计瓣膜面积为0.73平方厘米。13例(1.8%)患者被诊断为中风,偏瘫(9例)、意识丧失(3例)和/或失语(4例)是最常见的症状。在 70% 的病例中,神经症状在术后数周或数月内缓解或消失。13名患者中只有一名在30天内死亡(7.7%)。中风患者的体重指数(BMI)明显低于非中风患者,但两组患者的其他心血管疾病风险因素、术中因素或除中风以外的其他严重术后并发症发生率相似。中风组和非中风组的总住院时间中位数分别为14天和10天,其中重症监护室住院时间分别为2天和1天:结论:SAVR术后中风发生率较低(1.8%),与其他类似研究结果一致。结论:SAVR术后脑卒中发生率较低(1.8%),与其他类似研究结果一致。虽然脑卒中是一种严重并发症,但大多数围手术期脑卒中患者都能在术后30天内存活,而且大部分患者的神经症状都已恢复。
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来源期刊
Laeknabladid
Laeknabladid MEDICINE, GENERAL & INTERNAL-
CiteScore
0.50
自引率
25.00%
发文量
63
审稿时长
>12 weeks
期刊介绍: Læknablaðið er fræðirit sem birtir vísinda og yfirlitsgreinar og annað efni sem byggir á rannsóknum innan læknisfræði eða skyldra greina. Læknablaðið er gefið út af Læknafélagi Íslands. Blaðið er sent til allra félagsmanna. Það var fyrst gefið út árið 1904 en hefur komið samfellt út frá árinu 1915. Blaðið kemur út 11 sinnum á ári og er prentað í 2000 eintökum. Allt efni Læknablaðsins frá árinu 2000 er aðgengilegt á heimasíðu blaðsins á laeknabladid.is og er aðgangur endurgjaldslaus og öllum opinn.
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